Title: Book the Best Panama Canal Zone SPA Resorts - Spa Hotels in Panama Canal Zone | Expedia.ca [Panama Canal Zone Travel Guide](https://expedia.ca/Panama-Canal-Zone.dx6222968)[Hotels in Panama Canal Zone](https://expedia.ca/Panama-Canal-Zone-Hotels.d6222968.Travel-Guide-Hotels)[Vacation Rentals in Panama Canal Zone](https://expedia.ca/Panama-Canal-Zone-Vacation-Rentals.d6222968.Travel-Guide-VacationRentals)[Flights to Panama Canal Zone](https://expedia.ca/Cheap-Flights-To-Panama-Canal-Zone.d6222968.Travel-Guide-Flights)[Panama Canal Zone Car Rentals](https://expedia.ca/Car-Rentals-In-Panama-Canal-Zone.d6222968.Car-Rental-Guide)[Panama Canal Zone Vacation Packages](https://expedia.ca/Panama-Canal-Zone.d6222968.Destination-Travel-Guides) ![Colon showing building ruins and a garden](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/267000/267275-Colon.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Panama Canal Zone - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Panama Canal Zone Spa Hotels Tonight [Oct 31 - Nov 1](https://www.expedia.ca/Hotel-Search?regionId=6222968&startDate=2025-10-31&endDate=2025-11-01&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 1 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6222968&startDate=2025-11-01&endDate=2025-11-02&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6222968&startDate=2025-10-31&endDate=2025-11-02&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6222968&startDate=2025-11-07&endDate=2025-11-09&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Panama Canal Zone Spa Hotels ![Couples treatment rooms, Turkish bath, body treatments](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/46a37de3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/b883cd02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 6 AM to 8 PM, sun loungers](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/de56591c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/e77a4c37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Colon 2,000 Hotel & Casino Barrio Sur 8.2/10 Very good (799) "Everything was great good service and everything clean " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Zulema CA $123 CA $135 total includes taxes & fees Nov 15 - Nov 16 [](https://www.expedia.ca/Colon-Hotels-Radisson-Colon-2.h2147349.Hotel-Information) ![Sports massages, massages](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/4d4be0f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sundeck](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/f1edb578.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/ac5d93a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/4502bc4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SAND DIAMOND HOTEL Colon 8.4/10 Very good (198) "Great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert LahMar CA $166 CA $183 total includes taxes & fees Nov 6 - Nov 7 [](https://www.expedia.ca/Colon-Hotels-SAND-DIAMOND-HOTEL.h66722954.Hotel-Information) ![Couples treatment rooms, steam room, Turkish bath, body treatments](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/ff18df89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking, Golf View (Terrace)](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/d80494b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/2a51fa85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/1e4d9048.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City Juan Diaz 9.6/10 Exceptional (621) "great service" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gianluca CA $288 CA $317 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) ![Couples treatment rooms, sauna, steam room, body treatments](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/da95ec78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, 2 poolside bars, swim-up bar](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/a12fa485.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private beach, sun loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/e679a1c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/6d441b5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Playa Bonita Panama Veracruz 8.0/10 Very good (1006) "Had a great stay! The room was clean, comfortable, and exactly what we needed. The staff was super friendly and helpful, and the location was perfect. Everything went smoothly from check-in to check-out — would definitely stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Olsaris CA $245 CA $269 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information) ![Couples treatment rooms, sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/9086aeb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Preferred Club Junior Suite King Ocean View](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/247796e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast served, local and international cuisine](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/818dd731.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/f13ec34b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dreams Playa Bonita Panama - All Inclusive Veracruz 7.4/10 Good (1001) "It is a nice place for family time" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julián Andrés CA $381 CA $381 total includes taxes & fees Dec 2 - Dec 3 [](https://www.expedia.ca/Panama-City-Hotels-Dreams-Playa-Bonita-Panama.h12445554.Hotel-Information) ![Outdoor pool, open 7:00 AM to 10:30 PM, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/b7e843b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, down comforters, in-room safe](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/533cc611.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/ea26a97c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/d73825f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Riande Aeropuerto Hotel & Casino Tocumen 8.6/10 Excellent (1889) "Property location is great for the airport" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Amber CA $241 CA $265 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Tocumen-Hotels-Riande-Aeropuerto-Hotel-Casino.h26240.Hotel-Information) ![Hot tub, body treatments, aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/c754d1cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/a7b599bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; French cuisine](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/246e2668.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waldorf Astoria Panama Bella Vista 9.0/10 Wonderful (1000) "Great experience overall! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Reginald CA $250 CA $274 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ![Couples treatment rooms, sauna, hot tub, steam room, Turkish bath](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/59f34bde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4e8feb51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/bc945d5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Megapolis Hotel Panamá San Francisco 8.4/10 Very good (1164) "Great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark CA $159 CA $175 total includes taxes & fees Nov 10 - Nov 11 [](https://www.expedia.ca/Panama-City-Hotels-Megapolis-Hotel-Panama.h91995575.Hotel-Information) ![Couples treatment rooms, sauna, hot tub, steam room, Turkish bath](https://images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/d24ed1b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/c59b4539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room, 2 Double Beds, Sea View](https://images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/40a2c17a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/067e7d25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Decapolis Hotel Panama City San Francisco 8.6/10 Excellent (1384) "Very nice Hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marcos CA $119 CA $130 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Panama-City-Hotels-Decapolis-Hotel-Panama-City.h1082793.Hotel-Information) ![Couples treatment rooms, sauna, hot tub, Turkish bath, body treatments](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/57cdf539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/1f8c9ffe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/25adc131.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, sauna, hot tub, Turkish bath, body treatments](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/19f9d9c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sheraton Grand Panama San Francisco 8.6/10 Excellent (971) "Centrally located and friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julio CA $188 CA $206 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-15&endDate=2025-11-16®ionId=6222968&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Panama Canal Zone ### Top Panama Canal Zone attractions for a relaxing vacation The Panama Canal Zone offers a unique blend of adventure and relaxation, making it an excellent choice for travellers seeking spa hotels. Begin your journey with a visit to the Miraflores Locks, where you can witness the impressive engineering of the Panama Canal while enjoying the serene views of the waterway. For nature enthusiasts, the nearby Soberanía National Park provides a lush escape with opportunities for birdwatching and hiking through its verdant trails. If you're in the mood for some local culture, the Biomuseo showcases the biodiversity of Panama and offers engaging exhibits that are perfect for families. The vibrant Amador Causeway is ideal for leisurely walks or cycling, with stunning views of the Pacific Ocean and the city skyline. To unwind after a day of exploration, retreat to one of the luxurious hotels in the area, such as the elegant Westin Playa Bonita, which features a world-class spa offering rejuvenating treatments and stunning ocean views. Here, attentive service and plush amenities ensure a pampered experience, allowing you to fully relax and recharge. ## Top Panama Canal Zone Hotel Reviews ![Central Hotel Panama Casco Viejo](//images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg) ### Central Hotel Panama Casco Viejo 10/10 Excellent "Staffs were wonderful." [](https://expedia.ca/Panama-City-Hotels-Central-Hotel-Panama-Casco-Viejo.h15683502.Hotel-Information) ![The Westin Playa Bonita Panama](//images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/f767a768_y.jpg) ### The Westin Playa Bonita Panama 10/10 Excellent "We had an amazing family vacation. Especial mention for very exceptional people such as Franklin who is the best taxi driver and tour guy that you can get and Maria, who provides a personalized customer service in the buffet. They made our vacation unforgettable. They definitely upgrade any experience. " [](https://expedia.ca/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information) ![Hotel Riu Plaza Panama](//images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "The place was clean n always fresh , definitely my place to go whenever I come back to Panama. Love every bit of my stay " [](https://expedia.ca/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![JW Marriott Panama](//images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg) ### JW Marriott Panama 10/10 Excellent "The rooms were amazing " [](https://expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Radisson Hotel Panama Canal](//images.trvl-media.com/lodging/1000000/810000/809200/809149/23e8ad44_y.jpg) ### Radisson Hotel Panama Canal 10/10 Excellent "Superb customer service Ivonne Carrasco " [](https://expedia.ca/Amador-Hotels-Radisson-Hotel-Panama-Canal.h809149.Hotel-Information) ![Waldorf Astoria Panama](//images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e_y.jpg) ### Waldorf Astoria Panama 10/10 Excellent "Upon arrival to the Waldorf, Edgar was right there to assist us with our luggage to the room. It was at that moment I knew the W.A. hospitality was about to be extraordinary. " [](https://expedia.ca/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ![Dreams Playa Bonita Panama - All Inclusive](//images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg) ### Dreams Playa Bonita Panama - All Inclusive 10/10 Excellent "Staff was nice but not in any hurry" [](https://expedia.ca/Panama-City-Hotels-Dreams-Playa-Bonita-Panama.h12445554.Hotel-Information) ![Sheraton Grand Panama](//images.trvl-media.com/lodging/1000000/10000/1200/1161/179e52b4_y.jpg) ### Sheraton Grand Panama 10/10 Excellent "Relaxing but close by to everything " [](https://expedia.ca/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information)