Title: Best Hotels Near Wilkes Regional, Winston-Salem from CA $87 | Expedia.ca [Vacation Rentals in Winston-Salem](https://expedia.ca/Winston-Salem-Vacation-Rentals.d1605.Travel-Guide-VacationRentals)[Flights to Winston-Salem](https://expedia.ca/Cheap-Flights-To-Winston-Salem.d1605.Travel-Guide-Flights)[Things to do in Winston-Salem](https://expedia.ca/Things-To-Do-In-Winston-Salem.d1605.Travel-Guide-Activities)[Wilkes Regional Car Rentals](https://expedia.ca/Car-Rentals-In-Wilkes-Regional.d624548826147786752.Car-Rental-Guide)[Wilkes Regional Vacations](https://expedia.ca/Wilkes-Regional-Winston-Salem.d624548826147786752.Vacation-Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels near Wilkes Regional, Winston-Salem from CA $87 ### Change your mind Book hotels with free cancellation ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 7 - Oct 8](https://www.expedia.ca/Hotel-Search?regionId=624548826147786752&startDate=2025-10-07&endDate=2025-10-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 8 - Oct 9](https://www.expedia.ca/Hotel-Search?regionId=624548826147786752&startDate=2025-10-08&endDate=2025-10-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=624548826147786752&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=624548826147786752&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Top Hotels Close to Wilkes Regional ![Free continental breakfast](https://images.trvl-media.com/lodging/1000000/10000/5600/5561/c46a044c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, 1 King Bed](https://images.trvl-media.com/lodging/1000000/10000/5600/5561/80a523e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5600/5561/2d111cfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/5600/5561/0b44c388.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Winston-Salem Hanes Mall 1 km from Wilkes Regional 9.2/10 Wonderful (1001) "Great location" CA $153 CA $173 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Winston-Salem-Hotels-Hampton-Inn-Winston-Salem-Hanes-Mall.h5561.Hotel-Information) ![Standard Room, 1 King Bed with Sofa bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/210000/200700/200636/1519d557.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/210000/200700/200636/8d32a7db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/200700/200636/0c53a045.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/210000/200700/200636/9faf156f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Hanes Mall 0.7 km from Wilkes Regional 8.8/10 Excellent (1001) "Perfect place for our visit " CA $129 CA $149 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Winston-Salem-Hotels-Comfort-Suites-Hanes-Mall.h200636.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/120000/118500/118463/b8d76f7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/120000/118500/118463/w3995h2667x0y0-f1afb341.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/120000/118500/118463/ff23f9ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/120000/118500/118463/e4168366.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Winston-Salem Hanes Mall 1.3 km from Wilkes Regional 9.0/10 Wonderful (647) "Staff was friendly- especially Jeanette in the dining room! Beds are super comfy with lots of pillow options. Bathrooms are well appointed and clean." CA $153 CA $173 total includes taxes & fees Oct 14 - Oct 15 [](https://www.expedia.ca/Winston-Salem-Hotels-Fairfield-Inn-Suites-By-Marriott-Winston-Salem-Hanes-Mall.h118463.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/23000000/22170000/22168500/22168452/d4e5e580.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/23000000/22170000/22168500/22168452/5b9de55f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/23000000/22170000/22168500/22168452/458d22bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/23000000/22170000/22168500/22168452/c3a88797.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Winston-Salem Hanes Mall 1.8 km from Wilkes Regional 9.2/10 Wonderful (464) "The staff was very welcoming and continued to check in with us throughout our stay. The room was a great size and comfortable. " CA $159 CA $180 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Winston-Salem-Hotels-Home2-Suites-By-Hilton-Winston-Salem-Hanes-Mall.h22168452.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2780000/2774700/2774641/12e4c384.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2780000/2774700/2774641/c306df28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![42-inch LCD TV with cable channels, TV, Netflix](https://images.trvl-media.com/lodging/3000000/2780000/2774700/2774641/31804569.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2780000/2774700/2774641/72ab3d34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Springhill Suites by Marriott Winston-Salem Hanes Mall 2 km from Wilkes Regional 9.0/10 Wonderful (1006) "Like every Springhill suites I’ve stayed at, this one was wonderful. Clean, open design, excellent breakfast. " CA $149 CA $169 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Winston-Salem-Hotels-Springhill-Suites-By-Marriott-Winston-Salem-Hanes-Mall.h2774641.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/130000/129400/129363/d9aab144.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/130000/129400/129363/a6e74288.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/130000/129400/129363/5cd2d3b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/130000/129400/129363/70d96695.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Winston-Salem Hanes Mall 1.3 km from Wilkes Regional 8.4/10 Very good (698) "Hotel was clean, spacious and a good price." CA $139 CA $158 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/Winston-Salem-Hotels-Courtyard-By-Marriott-Winston-Salem-Hanes-Mall.h129363.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1950000/1942600/1942582/bdb026db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1950000/1942600/1942582/06260714.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1950000/1942600/1942582/77f809e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1950000/1942600/1942582/f23941a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Winston-Salem/Hanes Mall 2.4 km from Wilkes Regional 8.8/10 Excellent (703) "Clean and affordable " CA $173 CA $195 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Winston-Salem-Hotels-Hilton-Garden-Inn-Winston-SalemHanes-Mall.h1942582.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/18000000/17270000/17262400/17262315/441733c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17270000/17262400/17262315/923e30d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17262400/17262315/66465857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/18000000/17270000/17262400/17262315/d4d1d196.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Winston-Salem Hanes Mall 2.4 km from Wilkes Regional 8.6/10 Excellent (373) "my room couldve been cleaner" CA $174 CA $197 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Winston-Salem-Hotels-Residence-Inn-By-Marriott-Winston-Salem-Hanes-Mall.h17262315.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/1000000/160000/151400/151327/a043f81d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/160000/151400/151327/6528a440.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/160000/151400/151327/988445a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/160000/151400/151327/9c0be25c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn Hanes Mall Williamsburg Square, 0.9 km from Wilkes Regional 7.8/10 Good (1002) "Beautiful place " CA $94 CA $109 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Winston-Salem-Hotels-Sleep-Inn-Hanes-Mall.h151327.Hotel-Information) ![Queen Suite Two Queen Beds Accessible](https://images.trvl-media.com/lodging/105000000/104010000/104006400/104006376/80291a00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/105000000/104010000/104006400/104006376/e4e31f27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/105000000/104010000/104006400/104006376/b780d1d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, pillowtop beds, individually decorated](https://images.trvl-media.com/lodging/105000000/104010000/104006400/104006376/89064e85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### WoodSpring Suites Winston-Salem near Hanes Mall 2 km from Wilkes Regional 7.8/10 Good (236) "We checked out early. But we did get refunded. It is NOT A HOTEL. " CA $117 CA $132 total includes taxes & fees Oct 8 - Oct 9 [](https://www.expedia.ca/Winston-Salem-Hotels-Woodspring-Suites.h104006376.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12000/11901/7de40e3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/12000/11901/33380a1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/20000/12000/11901/f8428b82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking, Jetted Tub](https://images.trvl-media.com/lodging/1000000/20000/12000/11901/bb66c0f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Hanes Mall Hotel 2 km from Wilkes Regional 7.6/10 Good (1002) "Great stay " CA $108 CA $122 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Winston-Salem-Hotels-Best-Western-Plus-Hanes-Mall-Hotel.h11901.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/95000000/94800000/94799100/94799002/05eb08e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/95000000/94800000/94799100/94799002/217468c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/95000000/94800000/94799100/94799002/aaa5eb2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/95000000/94800000/94799100/94799002/bb04b6ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Suburban Studios Winston-Salem near Hanes Mall Williamsburg Square, 0.8 km from Wilkes Regional 7.2/10 Good (192) "I was staying alone, say 7 stars thought it would be safe. As soon as I get there a man tells me he’s gonna come to my room later then about midnight I hear loud knocking on the door. " CA $77 CA $87 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Winston-Salem-Hotels-Suburban-Studios.h94799002.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/290000/287500/287478/8634b3e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/290000/287500/287478/c8f50ee3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/290000/287500/287478/69a86446.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/290000/287500/287478/f1271a61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Winston-Salem 0.7 km from Wilkes Regional 7.0/10 Good (1002) "Staff was friendly, breakfast was nice." CA $104 CA $118 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Winston-Salem-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Winston-Salem.h287478.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/520000/520000/519916/09c40e3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/1000000/520000/520000/519916/ec0c3c59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/1000000/520000/520000/519916/430981f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/520000/519916/d784a632.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Hanes Mall 2.4 km from Wilkes Regional 6.8/10 (1006) "Outstanding accommodations. Reasonably priced, but without sacrificing any fundamental element. Front desk staff is exceptional, made me really feel welcome." CA $91 CA $103 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Winston-Salem-Hotels-Quality-Inn-Suites-Hanes-Mall.h519916.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/210000/200700/200637/f3fb4ebd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/210000/200700/200637/b8bde1c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/200700/200637/297403a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/210000/200700/200637/851941f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Winston-Salem 0.7 km from Wilkes Regional 5.2/10 (380) "The bathroom and the women and nice employees " CA $102 CA $115 total includes taxes & fees Oct 8 - Oct 9 [](https://www.expedia.ca/Winston-Salem-Hotels-Microtel-Inn-By-Wyndham-Winston-Salem.h200637.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/97000000/96550000/96547900/96547859/w2800h1865x0y2-9ea01da8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Alspaugh King Room](https://images.trvl-media.com/lodging/97000000/96550000/96547900/96547859/f7129d23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/97000000/96550000/96547900/96547859/ad9e5826.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/97000000/96550000/96547900/96547859/eb80b2eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Summit Street Inns 6.2 km from Wilkes Regional 9.8/10 Exceptional (209) "Absolutely perfect! " CA $183 CA $207 total includes taxes & fees Oct 9 - Oct 10 [](https://www.expedia.ca/Winston-Salem-Hotels-Summit-Street-Inns.h96547859.Hotel-Information) ![Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/26500/26487/98220637.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26500/26487/623cdcf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/30000/26500/26487/468ec72a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gift shop](https://images.trvl-media.com/lodging/1000000/30000/26500/26487/e8cc7313.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Historic Brookstown Inn, Trademark Collection by Wyndham 6.4 km from Wilkes Regional 9.6/10 Exceptional (1005) "Great place to stay and relax." CA $187 CA $211 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Winston-Salem-Hotels-The-Historic-Brookstown-Inn.h26487.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/20000000/19930000/19926500/19926432/5c4d4865.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/20000000/19930000/19926500/19926432/519f3444.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/20000000/19930000/19926500/19926432/2056bb37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/20000000/19930000/19926500/19926432/25540574.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Zevely Inn 6.4 km from Wilkes Regional 9.6/10 Exceptional (128) "Lovely traditional inn with a great breakfast." CA $240 CA $271 total includes taxes & fees Oct 8 - Oct 9 [](https://www.expedia.ca/Winston-Salem-Hotels-The-Zevely-Inn.h19926432.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/1000000/810000/802600/802537/182391e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/810000/802600/802537/0c37bff2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/810000/802600/802537/185fd23f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/810000/802600/802537/f5f15af9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Exp Winston Salem by IHG 4.1 km from Wilkes Regional 8.4/10 Very good (833) "Property and staff were great. Surrounding area had many shopping options" CA $121 CA $137 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Winston-Salem-Hotels-Holiday-Inn-Exp-Winston-Salem.h802537.Hotel-Information) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/10000/8600/8533/97b1f25b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8600/8533/w7360h4908x0y0-ceb51a06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9 AM to 9 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/8600/8533/4cd1ef05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/8600/8533/2026b213.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Winston-Salem Medical Center Area by IHG 4.8 km from Wilkes Regional 8.4/10 Very good (975) "Comfy beds, good breakfast, close to other places. This was my 2nd time staying here. Its very safe too, especially as woman traveling solo." CA $141 CA $159 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Winston-Salem-Hotels-Holiday-Inn-Express-Winston-Salem-Downtown-West.h8533.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-21&endDate=2025-10-22®ionId=624548826147786752&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top Wilkes Regional Hotel Reviews ![Fairfield Inn & Suites by Marriott Winston-Salem Hanes Mall](//images.trvl-media.com/lodging/1000000/120000/118500/118463/b8d76f7e_y.jpg) ### Fairfield Inn & Suites by Marriott Winston-Salem Hanes Mall 10/10 Excellent "What a nice girl checking me in! Great!" [](https://expedia.ca/Winston-Salem-Hotels-Fairfield-Inn-Suites-By-Marriott-Winston-Salem-Hanes-Mall.h118463.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Winston-Salem](//images.trvl-media.com/lodging/1000000/290000/287500/287478/8634b3e9_y.jpg) ### La Quinta Inn & Suites by Wyndham Winston-Salem 10/10 Excellent "Staff was friendly, breakfast was nice." [](https://expedia.ca/Winston-Salem-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Winston-Salem.h287478.Hotel-Information) ![Suburban Studios Winston-Salem near Hanes Mall](//images.trvl-media.com/lodging/95000000/94800000/94799100/94799002/05eb08e3_y.jpg) ### Suburban Studios Winston-Salem near Hanes Mall 10/10 Excellent "Great place to lodge " [](https://expedia.ca/Winston-Salem-Hotels-Suburban-Studios.h94799002.Hotel-Information) ![Hampton Inn Winston-Salem Hanes Mall](//images.trvl-media.com/lodging/1000000/10000/5600/5561/c46a044c_y.jpg) ### Hampton Inn Winston-Salem Hanes Mall 10/10 Excellent "V" [](https://expedia.ca/Winston-Salem-Hotels-Hampton-Inn-Winston-Salem-Hanes-Mall.h5561.Hotel-Information) ![Comfort Suites Hanes Mall](//images.trvl-media.com/lodging/1000000/210000/200700/200636/1519d557_y.jpg) ### Comfort Suites Hanes Mall 10/10 Excellent "Friendly staff and very clean rooms. Very clean hotel and a good breakfast in the morning. I really enjoyed my stay here. I’m traveling with my sprinter van business and I booked room here after the load was delivered. The next day my dispatch company was not ready for me another load by checking out. I explained my situation to the manager and he allowed me to sit in the lobby until I got my next load or get another room . That was very important to me. If I’m ever in this area again, I’ve found a good place to stay. Thank you for your hospitality." [](https://expedia.ca/Winston-Salem-Hotels-Comfort-Suites-Hanes-Mall.h200636.Hotel-Information) ![Sleep Inn Hanes Mall](//images.trvl-media.com/lodging/1000000/160000/151400/151327/a043f81d_y.jpg) ### Sleep Inn Hanes Mall 10/10 Excellent "Staff was great! Clean and Quiet" [](https://expedia.ca/Winston-Salem-Hotels-Sleep-Inn-Hanes-Mall.h151327.Hotel-Information) ![Springhill Suites by Marriott Winston-Salem Hanes Mall](//images.trvl-media.com/lodging/3000000/2780000/2774700/2774641/12e4c384_y.jpg) ### Springhill Suites by Marriott Winston-Salem Hanes Mall 10/10 Excellent "Overall it was great. " [](https://expedia.ca/Winston-Salem-Hotels-Springhill-Suites-By-Marriott-Winston-Salem-Hanes-Mall.h2774641.Hotel-Information) ![Home2 Suites by Hilton Winston-Salem Hanes Mall](//images.trvl-media.com/lodging/23000000/22170000/22168500/22168452/d4e5e580_y.jpg) ### Home2 Suites by Hilton Winston-Salem Hanes Mall 10/10 Excellent "Yes" [](https://expedia.ca/Winston-Salem-Hotels-Home2-Suites-By-Hilton-Winston-Salem-Hanes-Mall.h22168452.Hotel-Information) ![WoodSpring Suites Winston-Salem near Hanes Mall](//images.trvl-media.com/lodging/105000000/104010000/104006400/104006376/b75227cb_y.jpg) ### WoodSpring Suites Winston-Salem near Hanes Mall 10/10 Excellent "friendly staff it was great" [](https://expedia.ca/Winston-Salem-Hotels-Woodspring-Suites.h104006376.Hotel-Information) ### Hotels near Other Winston-Salem Attractions [](https://expedia.ca/Old-Salem-Hotels.0-l6066207-0.Travel-Guide-Filter-Hotels) ![Old Salem](https://mediaim.expedia.com/destination/2/a710ebbd3d82eea32a8cefc476b33d9f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Old Salem 4/5(4 reviews) You can spend time exploring the galleries in Old Salem during your trip to Winston-Salem. Amble around this family-friendly area's lush forest or attend a sporting event. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6066207) [](https://expedia.ca/Hanes-Mall-Hotels.0-l6066211-0.Travel-Guide-Filter-Hotels) #### Hanes Mall 3.5/5(2 reviews) You can do some window-shopping at Hanes Mall during your stay in Winston-Salem. Attend a sporting event or simply enjoy the local cheese shops while you're in the area. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6066211) [](https://expedia.ca/Novant-Health-Forsyth-Medical-Center-Hotels.0-l633990821891592192-0.Travel-Guide-Filter-Hotels) #### Novant Health Forsyth Medical Center Though Novant Health Forsyth Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of Winston-Salem while you are here. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=633990821891592192) [](https://expedia.ca/Wake-Forest-University-Baptist-Medical-Center-Hotels.0-l6066217-0.Travel-Guide-Filter-Hotels) #### Wake Forest University Baptist Medical Center Though Wake Forest University Baptist Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of Winston-Salem while you are here. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6066217) [](https://expedia.ca/Gods-Acre-Hotels.0-l553248621532657542-0.Travel-Guide-Filter-Hotels) #### God's Acre Enjoy a stop at God's Acre, a landmark worth seeing in Winston-Salem. Amble around this family-friendly area's lush forest or attend a sporting event. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532657542) [](https://expedia.ca/Truist-Stadium-Hotels.0-l6173806-0.Travel-Guide-Filter-Hotels) #### Truist Stadium Catch an event at Truist Stadium during your trip to Winston-Salem. Amble around this romantic area's lush forest or attend a sporting event. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6173806) ## Frequently asked questions ### What's the area like around Wilkes Regional? > Wilkes Regional is located in Winston-Salem. This family-friendly area is known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 19 hotels and other accommodations you'll find within a mile. ### What's the best hotel to stay close to Wilkes Regional? > [Comfort Suites Hanes Mall](https://www.expedia.ca/Winston-Salem-Hotels-Comfort-Suites-Hanes-Mall.h200636.Hotel-Information) is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located just a short 0.5 mi (0.7 km) from Wilkes Regional. Other good choices within a short distance include [Sleep Inn Hanes Mall](https://www.expedia.ca/Winston-Salem-Hotels-Sleep-Inn-Hanes-Mall.h151327.Hotel-Information) and [La Quinta Inn & Suites by Wyndham Winston-Salem](https://www.expedia.ca/Winston-Salem-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Winston-Salem.h287478.Hotel-Information). ### How many hotels should I expect to find close to Wilkes Regional? > Expedia has 19 hotels and other accommodations within a mile from Wilkes Regional. ### If I need to cancel the hotel reservation for my stay near Wilkes Regional, will I receive a refund? > Yes, most hotel reservations are refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to view the best deals near Wilkes Regional. ### What can I see and do near Wilkes Regional? > Study the collections at Old Salem, Southeastern Center for Contemporary Art, or Reynolda House Museum of American Art. You might spend a leisurely day outdoors at Reynolda Gardens and Hobby Park. Attractions like Theatre Alliance and Frank L. Horton Museum Center highlight the local culture.