Title: Hotels by Omni in Ohio River Valley from CA $299 | Expedia.ca [Ohio River Valley Travel Guide](https://expedia.ca/Ohio-River-Valley.dx6233674)[Hotels in Ohio River Valley](https://expedia.ca/Ohio-River-Valley-Hotels.d6233674.Travel-Guide-Hotels)[Vacation Rentals in Ohio River Valley](https://expedia.ca/Ohio-River-Valley-Vacation-Rentals.d6233674.Travel-Guide-VacationRentals)[Flights to Ohio River Valley](https://expedia.ca/Cheap-Flights-To-Ohio-River-Valley.d6233674.Travel-Guide-Flights)[Ohio River Valley Car Rentals](https://expedia.ca/Car-Rentals-In-Ohio-River-Valley.d6233674.Car-Rental-Guide)[Ohio River Valley Vacation Packages](https://expedia.ca/Ohio-River-Valley.d6233674.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/9/d8d7cee1461f7acfeb618115e5af115c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Omni in Ohio River Valley from CA $299 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Sep 25 - Sep 26](https://www.expedia.ca/Hotel-Search?regionId=6233674&startDate=2025-09-25&endDate=2025-09-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 26 - Sep 27](https://www.expedia.ca/Hotel-Search?regionId=6233674&startDate=2025-09-26&endDate=2025-09-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=6233674&startDate=2025-09-26&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6233674&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Ohio River Valley Omni Hotels ## Our top choices for Ohio River Valley Omni ![Sauna, body treatments, aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/4c7c479b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast served](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/w5757h3840x3y0-b0a2f211.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, cocktail bar, lobby lounge](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/547de83e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/e108d0ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omni Louisville Hotel Downtown Louisville 9.2/10 Wonderful (1623) "Great start and nice place for a relaxing stay " CA $277 CA $326 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information) ![Ballroom](https://images.trvl-media.com/lodging/1000000/20000/17700/17640/3e6b70fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/17700/17640/f225f86e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Loft, 1 King Bed with Sofa bed](https://images.trvl-media.com/lodging/1000000/20000/17700/17640/09be3a51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Accessible (Plaza Suite)](https://images.trvl-media.com/lodging/1000000/20000/17700/17640/29735869.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omni Severin Hotel Downtown Indianapolis 9.4/10 Exceptional (626) "Amazing stay" CA $255 CA $299 total includes taxes & fees Oct 9 - Oct 10 [](https://www.expedia.ca/Indianapolis-Hotels-Omni-Severin-Hotel.h17640.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-09&endDate=2025-10-10®ionId=6233674&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FOhio-River-Valley-Hotels-Omni.0-0-d6233674--bOmni.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FOhio-River-Valley-Hotels-Omni.0-0-d6233674--bOmni.Travel-Guide-Filter-Hotels) ## Top Ohio River Valley Hotel Reviews ![voco The Clair Cincinnati Downtown by IHG](//images.trvl-media.com/lodging/16000000/15400000/15399700/15399685/28577935_y.jpg) ### voco The Clair Cincinnati Downtown by IHG 10/10 Excellent "Best sleep I ever had away from home! After our concert ended, we were starving. We were so happy to see a very nice variety of frozen meals/snacks, available to purchase in the lobby, that filled us up immediately, since it was after midnight on a Thursday. Be sure to purchase parking when you make your reservation, since it is limited. The staff were all very helpful and knowledgeable. Everything was exceptionally clean." [](https://expedia.ca/Cincinnati-Hotels-Holiday-Inn-Hotel-Suites-Cincinnati-Downtown.h15399685.Hotel-Information) ![Sonesta Columbus Downtown](//images.trvl-media.com/lodging/1000000/30000/26900/26870/d5b1e434_y.jpg) ### Sonesta Columbus Downtown 10/10 Excellent "We were not aware of all the construction that was being done" [](https://expedia.ca/Columbus-Hotels-Sonesta-Columbus.h26870.Hotel-Information) ![Hilton Cincinnati Netherland Plaza](//images.trvl-media.com/lodging/1000000/10000/5900/5818/3a03c8ac_y.jpg) ### Hilton Cincinnati Netherland Plaza 10/10 Excellent "I stayed at this hotel for a conference and loved the historic character of the building. I appreciated having key access to the business center and the location was ideal." [](https://expedia.ca/Cincinnati-Hotels-Hilton-Cincinnati-Netherland-Plaza.h5818.Hotel-Information) ![Ironworks Hotel Indy](//images.trvl-media.com/lodging/20000000/19300000/19294100/19294032/02753ebe_y.jpg) ### Ironworks Hotel Indy 10/10 Excellent "Beautiful design and interestingly appointed rooms. The restaurants in and near the hotel are excellent. Cozy atmosphere." [](https://expedia.ca/Indianapolis-Hotels-Ironworks-Hotel-Indy.h19294032.Hotel-Information) ![I Hotel And Illinois Conference Center](//images.trvl-media.com/lodging/2000000/1900000/1897400/1897350/b24d7833_y.jpg) ### I Hotel And Illinois Conference Center 10/10 Excellent "Very nice and flexible staff when needing room changes!" [](https://expedia.ca/Champaign-Hotels-I-Hotel-And-Conference-Center.h1897350.Hotel-Information) ![Holiday Inn Express & Suites Cincinnati Riverfront by IHG](//images.trvl-media.com/lodging/1000000/50000/42500/42480/a153a670_y.jpg) ### Holiday Inn Express & Suites Cincinnati Riverfront by IHG 10/10 Excellent "Absolutely exceptional staff! We were immediately impressed with the kindness and friendliness of the great crew working there. From the front desk check in to the room cleaning associates and the ladies preparing the breakfast service, which was very good and had a great selection of items. Fresh ground coffee was available all day and the rooms were quiet, very clean and well furnished. I’ll definitely stay here again on my next trip." [](https://expedia.ca/Cincinnati-Hotels-Holiday-Inn-Express-Suites-Cincinnati-Riverfront.h42480.Hotel-Information) ![Omni Severin Hotel](//images.trvl-media.com/lodging/1000000/20000/17700/17640/3e6b70fc_y.jpg) ### Omni Severin Hotel 10/10 Excellent "always love to stay at the Omni. Right in the center of all the activity. From valet to bar to the breakfast, all perfect!" [](https://expedia.ca/Indianapolis-Hotels-Omni-Severin-Hotel.h17640.Hotel-Information) ![Hyatt Place Indianapolis Downtown](//images.trvl-media.com/lodging/34000000/33800000/33790100/33790005/c09b8e4c_y.jpg) ### Hyatt Place Indianapolis Downtown 10/10 Excellent "Great service easy to find and park and just an all around great place!!!" [](https://expedia.ca/Indianapolis-Hotels-Hyatt-Place-Indianapolis-Downtown.h33790005.Hotel-Information) ![Galt House Hotel Trademark Collection by Wyndham](//images.trvl-media.com/lodging/1000000/200000/191500/191434/b5c46c3f_y.jpg) ### Galt House Hotel Trademark Collection by Wyndham 10/10 Excellent "Fastest and easiest check in! Very clean, quiet, and beautiful!" [](https://expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [1 Star Hotels in Historic Route 66](https://www.expedia.ca/1Star-Historic-Route-66-Hotels.s10-0-d702654640613646336.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Historic Route 66](https://www.expedia.ca/2Star-Historic-Route-66-Hotels.s20-0-d702654640613646336.Travel-Guide-Filter-Hotels) - [B&B in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Bed-And-Breakfast.d702654640613646336-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cabin Rentals in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Cabins.d702654640613646336-aaCabins.Travel-Guide-Accommodation) - [Condo Rentals in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Condos.d702654640613646336-aaCondos.Travel-Guide-Accommodation) - [Cottages in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Cottages.d702654640613646336-aaCottages.Travel-Guide-Accommodation) - 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