Title: Book the Best Ohio River Valley LUXURY Hotels - Upscale Hotels in Ohio River Valley | Expedia.ca [Ohio River Valley Travel Guide](https://expedia.ca/Ohio-River-Valley.dx6233674)[Hotels in Ohio River Valley](https://expedia.ca/Ohio-River-Valley-Hotels.d6233674.Travel-Guide-Hotels)[Vacation Rentals in Ohio River Valley](https://expedia.ca/Ohio-River-Valley-Vacation-Rentals.d6233674.Travel-Guide-VacationRentals)[Flights to Ohio River Valley](https://expedia.ca/Cheap-Flights-To-Ohio-River-Valley.d6233674.Travel-Guide-Flights)[Ohio River Valley Car Rentals](https://expedia.ca/Car-Rentals-In-Ohio-River-Valley.d6233674.Car-Rental-Guide)[Ohio River Valley Vacation Packages](https://expedia.ca/Ohio-River-Valley.d6233674.Destination-Travel-Guides) ![Indianapolis featuring autumn leaves and a cemetery](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/25000/25344-Indianapolis.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Ohio River Valley ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Ohio River Valley Luxury Hotels Tonight [Oct 10 - Oct 11](https://www.expedia.ca/Hotel-Search?regionId=6233674&startDate=2025-10-10&endDate=2025-10-11&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 11 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6233674&startDate=2025-10-11&endDate=2025-10-12&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6233674&startDate=2025-10-10&endDate=2025-10-12&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6233674&startDate=2025-10-17&endDate=2025-10-19&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Ohio River Valley Luxury Hotels ![Meeting facility](https://images.trvl-media.com/lodging/2000000/1290000/1287500/1287480/w3822h2860x18y0-dc47fc22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/2000000/1290000/1287500/1287480/9b21e16f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/2000000/1290000/1287500/1287480/3cf8c2c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/2000000/1290000/1287500/1287480/w2558h3836x3y4-7244cc45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Conrad Indianapolis Downtown Indianapolis 9.2/10 Wonderful (1007) "Stayed in the Modern Suite. Very nice room! Close to restaurants and walking distance to Lucas Oil Stadium. Would definitely stay here again. " CA $302 CA $357 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Indianapolis-Hotels-Conrad-Indianapolis.h1287480.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/a9b7038a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (Asleep in the Cyclone)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/fdd94051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/22b7d23e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/cef338e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 21c Museum Hotel Louisville Downtown Louisville 9.4/10 Exceptional (1004) "Great stay overall. " CA $226 CA $273 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1750000/1745100/1745075/220feee7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![15 restaurants, breakfast served](https://images.trvl-media.com/lodging/2000000/1750000/1745100/1745075/95e75b78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/2000000/1750000/1745100/1745075/14a6fe74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves lunch and dinner](https://images.trvl-media.com/lodging/2000000/1750000/1745100/1745075/97ea6860.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### West Baden Springs Hotel West Baden Springs 9.6/10 Exceptional (310) [](https://www.expedia.ca/West-Baden-Springs-Hotels-West-Baden-Springs-Hotel.h1745075.Hotel-Information) ![1 bedroom, Egyptian cotton sheets, premium bedding, in-room safe](https://images.trvl-media.com/lodging/6000000/5290000/5287100/5287002/e40ec4ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/6000000/5290000/5287100/5287002/5b64e900.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dinner and brunch served](https://images.trvl-media.com/lodging/6000000/5290000/5287100/5287002/17dd1cba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/6000000/5290000/5287100/5287002/083528eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 21c Museum Hotel Cincinnati Downtown Cincinnati 8.8/10 Excellent (1004) "Great location and atmosphere" CA $225 CA $276 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Cincinnati-Hotels-21c-Museum-Hotel-Cincinnati.h5287002.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/20000/12500/12411/90dd12e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/12500/12411/fdaa6912.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/12500/12411/05efa2e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gift shop](https://images.trvl-media.com/lodging/1000000/20000/12500/12411/f0cc451d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Cincinnatian Hotel Curio Collection by Hilton Downtown Cincinnati 7.6/10 Good (1005) "Nice Hotel to spend the nights in a very accessible location. Great staff." CA $206 CA $246 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Cincinnati-Hotels-The-Cincinnatian-Hotel-Curio-Collection-By-Hilton.h12411.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/840e31de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/f0221042.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/4fd8456f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/2a2a7fb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Brown Hotel Downtown Louisville 9.4/10 Exceptional (1085) "The hotel and the staff were great." CA $213 CA $251 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information) ![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/b5c46c3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/9c82234b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/ab0af7cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/23521baa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Galt House Hotel Trademark Collection by Wyndham Downtown Louisville 9.0/10 Wonderful (3671) "Th Galt House is a beautiful place to stay. " CA $194 CA $228 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/16000000/15110000/15108500/15108459/53b2e008.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Loft, 1 King Bed, Kitchenette | Living area](https://images.trvl-media.com/lodging/16000000/15110000/15108500/15108459/e8eba286.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/16000000/15110000/15108500/15108459/c391327c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room, 1 King Bed, Kitchenette](https://images.trvl-media.com/lodging/16000000/15110000/15108500/15108459/c26bf422.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Covington Cincinnati Riverfront Covington 9.6/10 Exceptional (1012) "Very nice and trendy hotel. Large clean rooms with great design" CA $276 CA $311 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Cincinnati-Hotels-Hotel-Covington-Cincinnati-Riverfront.h15108459.Hotel-Information) ![Dinner served](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/e02820b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/c4d1fb67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/f30004bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/5bea9d61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites Louisville Downtown Downtown Louisville 9.0/10 Wonderful (1022) "Nice room and great breakfast!! " CA $194 CA $229 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/690000/687800/687701/574acdfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/690000/687800/687701/2b30ef66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, individually furnished, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/690000/687800/687701/a7fe0148.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/1000000/690000/687800/687701/1802b8f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Olentangy Motor Inn Grandview Heights 9.0/10 Wonderful (1223) "Always a great experience, when I stay quarterly. Quiet, immaculate room, and always great front desk staff." CA $139 CA $164 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Columbus-Hotels-Olentangy-Motor-Inn.h687701.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-24&endDate=2025-10-25®ionId=6233674&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top Ohio River Valley Hotel Reviews ![Clarion Pointe Louisville East](//images.trvl-media.com/lodging/1000000/20000/17000/16984/dc3641e7_y.jpg) ### Clarion Pointe Louisville East 10/10 Excellent "Was welcome to buy a very nice employee, I saw her often during the week I was there and she was always greeting and friendly I had a good experience also with another gentleman when I locked myself out of my room. Exception employees, except for the nighttime one which you could not see because I found he was stretched out on a couch on his phone more than one night. I thought it was a registered guest until he started speaking to a guest who walked up to pay for a pop. Shocked. think there’d be cameras in the company would not find this appropriate. considering you can tell this company takes pride in their hotel. Other than that, it is a hotel that you do not hear a lot of road noise. Comfy beds and large rooms. The location is excellent and the warm breakfast was much appreciated every morning. It kept it fully stocked, unlike many other hotels who stop filling 30 minutes or so before the end of the meal. Definitely made a note that I will stay here again next time when I come through again." [](https://expedia.ca/Louisville-Hotels-Quality-Inn-Louisville-East.h16984.Hotel-Information) ![Galt House Hotel Trademark Collection by Wyndham](//images.trvl-media.com/lodging/1000000/200000/191500/191434/b5c46c3f_y.jpg) ### Galt House Hotel Trademark Collection by Wyndham 10/10 Excellent "Wi-Fi connection was good. Room was a suite, which was awesome. I would only suggest more bright lighting in the living area, and some kind of lighting in closets. " [](https://expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) ![Radisson Hotel Cincinnati Riverfront](//images.trvl-media.com/lodging/1000000/10000/2800/2755/68cff2fd_y.jpg) ### Radisson Hotel Cincinnati Riverfront 10/10 Excellent "Yes" [](https://expedia.ca/Cincinnati-Hotels-Radisson-Hotel-Cincinnati-Riverfront.h2755.Hotel-Information) ![Crowne Plaza Louisville Airport Expo Ctr by IHG](//images.trvl-media.com/lodging/1000000/20000/11400/11386/a43a56f2_y.jpg) ### Crowne Plaza Louisville Airport Expo Ctr by IHG 10/10 Excellent "Every thing " [](https://expedia.ca/Louisville-Hotels-Crowne-Plaza-Louisville-Airport-Expo-Center.h11386.Hotel-Information) ![Drury Inn & Suites Louisville North](//images.trvl-media.com/lodging/13000000/12070000/12067900/12067887/cd166214_y.jpg) ### Drury Inn & Suites Louisville North 10/10 Excellent "Everyone was friendly and welcoming " [](https://expedia.ca/Louisville-Hotels-Drury-Inn-Suites-Louisville-North.h12067887.Hotel-Information) ![Embassy Suites Louisville Downtown](//images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/e02820b0_y.jpg) ### Embassy Suites Louisville Downtown 10/10 Excellent "Rooms and location was fantastic. Close to 4th street live and whiskey row. " [](https://expedia.ca/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information) ![Hyatt Place Louisville East](//images.trvl-media.com/lodging/1000000/30000/22000/21946/e70dcaa7_y.jpg) ### Hyatt Place Louisville East 10/10 Excellent "Clean room and convenience in location. " [](https://expedia.ca/Louisville-Hotels-Hyatt-Place-Louisville-East.h21946.Hotel-Information) ![Drury Inn & Suites Louisville East](//images.trvl-media.com/lodging/1000000/800000/793000/792962/d2587f53_y.jpg) ### Drury Inn & Suites Louisville East 10/10 Excellent "Very good staff and property were great! " [](https://expedia.ca/Louisville-Hotels-Drury-Inn-Suites-Louisville-East.h792962.Hotel-Information) ![The Brown Hotel](//images.trvl-media.com/lodging/1000000/10000/9900/9861/840e31de_y.jpg) ### The Brown Hotel 10/10 Excellent "Beautiful Hotel Staff professional and Friendly Rooms clean and nice Nice bathroom Walkable to restaurants and bars The Brown Hotel has a excellent restaurant and bar " [](https://expedia.ca/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [1 Star Hotels in Historic Route 66](https://www.expedia.ca/1Star-Historic-Route-66-Hotels.s10-0-d702654640613646336.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Historic Route 66](https://www.expedia.ca/2Star-Historic-Route-66-Hotels.s20-0-d702654640613646336.Travel-Guide-Filter-Hotels) - [B&B in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Bed-And-Breakfast.d702654640613646336-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cabin Rentals in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Cabins.d702654640613646336-aaCabins.Travel-Guide-Accommodation) - [Chalets in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Chalets.d702654640613646336-aaChalets.Travel-Guide-Accommodation) - [Condo Rentals in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Condos.d702654640613646336-aaCondos.Travel-Guide-Accommodation) - [Cottages in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Cottages.d702654640613646336-aaCottages.Travel-Guide-Accommodation) - [Hostels in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Hostels.d702654640613646336-aaHostels.Travel-Guide-Accommodation) - [Cheap Hotels in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Hotels-Cheap-Hotels.0-0-d702654640613646336-tCheapHotels.Travel-Guide-Filter-Hotels) - [Club Quarters Hotels in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Hotels-Club-Quarters.0-0-d702654640613646336--bClubQuarters.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Hotels-Luxury-Hotel.0-0-d702654640613646336-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Motel 6 Hotels in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Hotels-Motel-6.0-0-d702654640613646336--bMotel6.Travel-Guide-Filter-Hotels) - [Red Roof Inn Hotels in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Hotels-Red-Roof-Inn.0-0-d702654640613646336--bRedRoofInn.Travel-Guide-Filter-Hotels) - [Sonesta Hotel in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Hotels-Sonesta-Hotel.0-0-d702654640613646336--bSonestaHotel.Travel-Guide-Filter-Hotels) - [Wyndham Extra Holidays Hotels in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Hotels-Wyndham-Extra-Holidays.0-0-d702654640613646336--bWyndhamExtraHolidays.Travel-Guide-Filter-Hotels) - [Historic Route 66 Hotels](https://www.expedia.ca/Historic-Route-66-Hotels.d702654640613646336.Travel-Guide-Hotels) - [Inns in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Inns.d702654640613646336-aaInns.Travel-Guide-Accommodation) - [Lodges in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Lodges.d702654640613646336-aaLodges.Travel-Guide-Accommodation) - [Motels in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Motels.d702654640613646336-aaMotels.Travel-Guide-Accommodation) - [Resorts in Historic Route 66](https://www.expedia.ca/Historic-Route-66-Resort-Hotels.d702654640613646336-aaResortHotels.Travel-Guide-Accommodation) - [Hotels near Ohio River](https://www.expedia.ca/Ohio-River-Hotels.0-l681940626945888256-0.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Southeastern Indiana](https://www.expedia.ca/Southeastern-Indiana-Hotels-Boutique-Hotel.0-0-d6233889-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Casino Hotels in Southeastern Indiana](https://www.expedia.ca/Southeastern-Indiana-Hotels-Casino-Hotel.0-0-d6233889-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in Southeastern Indiana](https://www.expedia.ca/Southeastern-Indiana-Hotels-Couples-Resorts-Hotels.0-0-d6233889-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Hotels with smoking rooms in Southeastern Indiana](https://www.expedia.ca/Southeastern-Indiana-Hotels-Hotels-With-Smoking-Rooms.0-0-d6233889-tHotelswithsmokingrooms.Travel-Guide-Filter-Hotels) - [Red Roof Inn Hotels in Southeastern Indiana](https://www.expedia.ca/Southeastern-Indiana-Hotels-Red-Roof-Inn.0-0-d6233889--bRedRoofInn.Travel-Guide-Filter-Hotels) - [Waterpark Hotels in Southeastern Indiana](https://www.expedia.ca/Southeastern-Indiana-Hotels-Waterpark-Hotels.0-0-d6233889-tWaterparkHotels.Travel-Guide-Filter-Hotels) - [Southeastern Indiana Hotels](https://www.expedia.ca/Southeastern-Indiana-Hotels.d6233889.Travel-Guide-Hotels) - [Motels in Southeastern Indiana](https://www.expedia.ca/Southeastern-Indiana-Motels.d6233889-aaMotels.Travel-Guide-Accommodation) - [B&B in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Bed-And-Breakfast.d6059635-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cabin Rentals in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Cabins.d6059635-aaCabins.Travel-Guide-Accommodation) - [Chalets in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Chalets.d6059635-aaChalets.Travel-Guide-Accommodation) - [Hostels in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hostels.d6059635-aaHostels.Travel-Guide-Accommodation) - [Beach Hotel Hotels in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Beach-Hotel.0-0-d6059635-tBeachHotel.Travel-Guide-Filter-Hotels) - [Casino Hotels in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Casino-Hotel.0-0-d6059635-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Cheap-Hotels.0-0-d6059635-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hilton Hotels in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Hilton-Hotels.0-0-d6059635--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Hotels with Free Parking in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Hotels-With-Free-Parking.0-0-d6059635-tHotelswithFreeParking.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Hotels-With-Hot-Tubs.0-0-d6059635-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Hotels with Tennis Courts in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Hotels-With-Tennis-Courts.0-0-d6059635-tHotelswithTennisCourts.Travel-Guide-Filter-Hotels) - [La Quinta Inn & Suites Hotels in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-La-Quinta-Inn-Suites.0-0-d6059635--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Luxury-Hotel.0-0-d6059635-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Marriott Hotels & Resorts in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Marriott-Hotels-Resorts.0-0-d6059635--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) - [Omni Hotels in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Omni.0-0-d6059635--bOmni.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Pet-Friendly-Hotel.0-0-d6059635-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Red Roof Inn Hotels in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Red-Roof-Inn.0-0-d6059635--bRedRoofInn.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Romantic-Hotel.0-0-d6059635-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Waterpark Hotels in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Hotels-Waterpark-Hotels.0-0-d6059635-tWaterparkHotels.Travel-Guide-Filter-Hotels) - [Southern Indiana Hotels](https://www.expedia.ca/Southern-Indiana-Hotels.d6059635.Travel-Guide-Hotels) - [Motels in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Motels.d6059635-aaMotels.Travel-Guide-Accommodation) - [Resorts in Southern Indiana](https://www.expedia.ca/Southern-Indiana-Resort-Hotels.d6059635-aaResortHotels.Travel-Guide-Accommodation) - [Cheap Hotels in Southwestern Indiana](https://www.expedia.ca/Southwestern-Indiana-Hotels-Cheap-Hotels.0-0-d6233876-tCheapHotels.Travel-Guide-Filter-Hotels) - [Historic Hotels in Southwestern Indiana](https://www.expedia.ca/Southwestern-Indiana-Hotels-Historic-Hotel.0-0-d6233876-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Southwestern Indiana](https://www.expedia.ca/Southwestern-Indiana-Hotels-Hotels-With-Hot-Tubs.0-0-d6233876-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Southwestern Indiana](https://www.expedia.ca/Southwestern-Indiana-Hotels-Pet-Friendly-Hotel.0-0-d6233876-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Red Roof Inn Hotels in Southwestern Indiana](https://www.expedia.ca/Southwestern-Indiana-Hotels-Red-Roof-Inn.0-0-d6233876--bRedRoofInn.Travel-Guide-Filter-Hotels) - [Southwestern Indiana Hotels](https://www.expedia.ca/Southwestern-Indiana-Hotels.d6233876.Travel-Guide-Hotels) - [Resorts in Southwestern Indiana](https://www.expedia.ca/Southwestern-Indiana-Resort-Hotels.d6233876-aaResortHotels.Travel-Guide-Accommodation) - [Flights to Historic Route 66](https://www.expedia.ca/Cheap-Flights-To-Historic-Route-66.d702654640613646336.Travel-Guide-Flights) - [Flights to Southern Indiana](https://www.expedia.ca/Cheap-Flights-To-Southern-Indiana.d6059635.Travel-Guide-Flights) - [Flights to Southwestern Indiana](https://www.expedia.ca/Cheap-Flights-To-Southwestern-Indiana.d6233876.Travel-Guide-Flights) - [Flights from Atlanta to Southern Indiana](https://www.expedia.ca/lp/flights/178232/6059635/atlanta-to-southern-indiana) - [Flights from Philadelphia to Southern Indiana](https://www.expedia.ca/lp/flights/178297/6059635/philadelphia-to-southern-indiana) - [Flights from Phoenix to Historic Route 66](https://www.expedia.ca/lp/flights/178298/702654640613646336/phoenix-to-historic-route-66) - [Flights from Seattle to Southern Indiana](https://www.expedia.ca/lp/flights/178307/6059635/seattle-to-southern-indiana) - [Flights from Buffalo to Southern Indiana](https://www.expedia.ca/lp/flights/602674/6059635/buffalo-to-southern-indiana) - [Historic Route 66 Vacations](https://www.expedia.ca/Historic-Route-66.d702654640613646336.Destination-Travel-Guides) - [Southern Indiana Vacations](https://www.expedia.ca/Southern-Indiana.d6059635.Destination-Travel-Guides) - [Visit Southern Indiana](https://www.expedia.ca/Southern-Indiana.dx6059635) - [Visit Southwestern Indiana](https://www.expedia.ca/Southwestern-Indiana.dx6233876) - [Ada Rental Cars in Historic Route 66](https://www.expedia.ca/ADA-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1109.Car-Rental-Guide-Suppliers) - [Airport Van Rental Rental Cars in Historic Route 66](https://www.expedia.ca/Airport-Van-Rental-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1092.Car-Rental-Guide-Suppliers) - [Amigo Autos Rental Cars in Historic Route 66](https://www.expedia.ca/Amigo-Autos-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1128.Car-Rental-Guide-Suppliers) - [Avis Rental Cars in Historic Route 66](https://www.expedia.ca/Avis-Car-Rentals-In-Historic-Route-66.d702654640613646336-c41.Car-Rental-Guide-Suppliers) - [Car rentals near Historic Route 66](https://www.expedia.ca/Car-Rentals-In-Historic-Route-66.d702654640613646336.Car-Rental-Guide) - [Click & Rent Rental Cars in Historic Route 66](https://www.expedia.ca/Click-Rent-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1089.Car-Rental-Guide-Suppliers) - [Convertible Car Rentals in Historic Route 66](https://www.expedia.ca/Convertible-Car-Rentals-In-Historic-Route-66.d702654640613646336-tConvertible.Car-Rental-Guide-Class) - [Drive-A-Matic Rental Cars in Historic Route 66](https://www.expedia.ca/Drive-A-Matic-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1082.Car-Rental-Guide-Suppliers) - [Drive on Holidays Rental Cars in Historic Route 66](https://www.expedia.ca/Drive-On-Holidays-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1050.Car-Rental-Guide-Suppliers) - [Firefly Rental Cars in Historic Route 66](https://www.expedia.ca/Firefly-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1040.Car-Rental-Guide-Suppliers) - [Firefly Portugal Rental Cars in Historic Route 66](https://www.expedia.ca/Firefly-Portugal-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1071.Car-Rental-Guide-Suppliers) - [First Car Rental Rental Cars in Historic Route 66](https://www.expedia.ca/First-Car-Rental-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1107.Car-Rental-Guide-Suppliers) - [Hertz Rental Cars in Historic Route 66](https://www.expedia.ca/Hertz-Car-Rentals-In-Historic-Route-66.d702654640613646336-c40.Car-Rental-Guide-Suppliers) - [Jumbo Car Rental Cars in Historic Route 66](https://www.expedia.ca/Jumbo-Car-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1067.Car-Rental-Guide-Suppliers) - [Luxury Car Rentals in Historic Route 66](https://www.expedia.ca/Luxury-Car-Rentals-In-Historic-Route-66.d702654640613646336-tLuxury.Car-Rental-Guide-Class) - [Midway Car Rental Rental Cars in Historic Route 66](https://www.expedia.ca/Midway-Car-Rental-Car-Rentals-In-Historic-Route-66.d702654640613646336-c27.Car-Rental-Guide-Suppliers) - [National Car Rental Rental Cars in Historic Route 66](https://www.expedia.ca/National-Car-Rental-Car-Rentals-In-Historic-Route-66.d702654640613646336-c42.Car-Rental-Guide-Suppliers) - [Offer Car Hire Rental Cars in Historic Route 66](https://www.expedia.ca/Offer-Car-Hire-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1141.Car-Rental-Guide-Suppliers) - [Orlando Rental Cars in Historic Route 66](https://www.expedia.ca/Orlando-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1047.Car-Rental-Guide-Suppliers) - [Pickup Car Rentals in Historic Route 66](https://www.expedia.ca/Pickup-Car-Rentals-In-Historic-Route-66.d702654640613646336-tPickup.Car-Rental-Guide-Class) - [Priceless Car Rental Rental Cars in Historic Route 66](https://www.expedia.ca/Priceless-Car-Rental-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1060.Car-Rental-Guide-Suppliers) - [Rent A Wreck Rental Cars in Historic Route 66](https://www.expedia.ca/Rent-A-Wreck-Car-Rentals-In-Historic-Route-66.d702654640613646336-c33.Car-Rental-Guide-Suppliers) - [Rent A Wreck Rental Cars in Southern Indiana](https://www.expedia.ca/Rent-A-Wreck-Car-Rentals-In-Southern-Indiana.d6059635-c33.Car-Rental-Guide-Suppliers) - [Routes Rental Cars in Historic Route 66](https://www.expedia.ca/Routes-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1101.Car-Rental-Guide-Suppliers) - [Thai Cars Rental Cars in Historic Route 66](https://www.expedia.ca/Thai-Cars-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1027.Car-Rental-Guide-Suppliers) - [Thrifty Car Rental Rental Cars in Historic Route 66](https://www.expedia.ca/Thrifty-Car-Rental-Car-Rentals-In-Historic-Route-66.d702654640613646336-c45.Car-Rental-Guide-Suppliers) - [Van Car Rentals in Historic Route 66](https://www.expedia.ca/Van-Car-Rentals-In-Historic-Route-66.d702654640613646336-tVan.Car-Rental-Guide-Class) - [Wiber Rental Cars in Historic Route 66](https://www.expedia.ca/WIber-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1127.Car-Rental-Guide-Suppliers) - [Historic Route 66 Vacation Rentals](https://www.expedia.ca/Historic-Route-66-Vacation-Rentals.d702654640613646336.Travel-Guide-VacationRentals) - [Things to do in Southern Indiana](https://www.expedia.ca/Things-To-Do-In-Southern-Indiana.d6059635.Travel-Guide-Activities) - [Book Luxury Hotels in Ohio River Valley on Expedia.com](https://www.expedia.com/Ohio-River-Valley-Hotels-Luxury-Hotel.0-0-d6233674-tLuxuryHotel.Travel-Guide-Filter-Hotels)