Title: Book the Best Twain LUXURY Hotels - Upscale Hotels in Twain, Iowa City | Expedia.ca [Vacation Rentals in Iowa City](https://expedia.ca/Iowa-City-Vacation-Rentals.d10426.Travel-Guide-VacationRentals)[Flights to Iowa City](https://expedia.ca/Cheap-Flights-To-Iowa-City.d10426.Travel-Guide-Flights)[Things to do in Iowa City](https://expedia.ca/Things-To-Do-In-Iowa-City.d10426.Travel-Guide-Activities)[Twain Car Rentals](https://expedia.ca/Car-Rentals-In-Twain.d553248635976481162.Car-Rental-Guide)[Twain Vacations](https://expedia.ca/Twain.d553248635976481162.Destination-Travel-Guides) ![The City Of Cedar Rapids](https://images.trvl-media.com/place/553248635976481162/9de55ec9-c220-4332-933c-829d106fa4ec.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Luxury Hotels in Twain, Iowa City - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Twain Luxury Hotels Tonight [Dec 19 - Dec 20](https://www.expedia.ca/Hotel-Search?regionId=553248635976481162&startDate=2025-12-19&endDate=2025-12-20&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Dec 20 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=553248635976481162&startDate=2025-12-20&endDate=2025-12-21&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=553248635976481162&startDate=2025-12-19&endDate=2025-12-21&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248635976481162&startDate=2025-12-26&endDate=2025-12-28&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Our top choices for Twain luxury hotels ![Hypo-allergenic bedding, pillowtop beds, individually decorated, desk](https://images.trvl-media.com/lodging/1000000/10000/400/388/149388ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, pillowtop beds, individually decorated, desk](https://images.trvl-media.com/lodging/1000000/10000/400/388/adda1b9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, pillowtop beds, individually decorated, desk](https://images.trvl-media.com/lodging/1000000/10000/400/388/43470dc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/400/388/e7c033ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Highlander Hotel Iowa City, an Ascend Collection Hotel [](https://www.expedia.ca/Iowa-City-Hotels-The-Highlander-Hotel.h388.Hotel-Information) Iowa City 8.8/10 Excellent (950) "Great hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lilia CA $172 CA $193 total includes taxes & fees Jan 7 - Jan 8, 2026 [](https://www.expedia.ca/Iowa-City-Hotels-The-Highlander-Hotel.h388.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1400000/1394100/1394020/2907f6a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1400000/1394100/1394020/cbb59bc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1400000/1394100/1394020/d03fe654.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1400000/1394100/1394020/1c085740.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Coralville Hotel & Conference Center [](https://www.expedia.ca/Coralville-Hotels-Hyatt-Regency-Coralville-Hotel-Conference-Center.h1394020.Hotel-Information) Iowa River Landing 9.2/10 Wonderful (1000) "Beautiful, clean, great rooms and great location!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brad CA $163 CA $185 total includes taxes & fees Dec 25 - Dec 26 [](https://www.expedia.ca/Coralville-Hotels-Hyatt-Regency-Coralville-Hotel-Conference-Center.h1394020.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/22000/21977/425543f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast served](https://images.trvl-media.com/lodging/1000000/30000/22000/21977/1718bcd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/22000/21977/eae92aef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22000/21977/e464b985.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Graduate by Hilton Iowa City [](https://www.expedia.ca/Iowa-City-Hotels-Graduate-Iowa-City.h21977.Hotel-Information) Downtown 9.2/10 Wonderful (1022) "Great hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark CA $134 CA $151 total includes taxes & fees Dec 26 - Dec 27 [](https://www.expedia.ca/Iowa-City-Hotels-Graduate-Iowa-City.h21977.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-02&endDate=2026-01-03®ionId=553248635976481162&adults=2&sort=LUXURY&star=40,50&openPlayBack=true) ## Top Twain Hotel Reviews ![Heartland Inn](https://images.trvl-media.com/lodging/1000000/60000/50200/50147/076a79cf_y.jpg) ### Heartland Inn 10/10 Excellent "The room was great, clean and spacious!" [](https://expedia.ca/Coralville-Hotels-Heartland-Inn.h50147.Hotel-Information) ![Country Inn & Suites by Radisson, Coralville, IA](https://images.trvl-media.com/lodging/2000000/1100000/1093000/1092916/88ed9224_y.jpg) ### Country Inn & Suites by Radisson, Coralville, IA 10/10 Excellent "Yes" [](https://expedia.ca/Coralville-Hotels-Country-Inn-Suites-By-Radisson.h1092916.Hotel-Information) ![AmericInn by Wyndham Coralville](https://images.trvl-media.com/lodging/1000000/570000/565100/565097/2cd8bd80_y.jpg) ### AmericInn by Wyndham Coralville 10/10 Excellent "Staff was excellent " [](https://expedia.ca/Coralville-Hotels-AmericInn-By-Wyndham-Coralville.h565097.Hotel-Information) ![Hyatt Regency Coralville Hotel & Conference Center](https://images.trvl-media.com/lodging/2000000/1400000/1394100/1394020/2907f6a2_y.jpg) ### Hyatt Regency Coralville Hotel & Conference Center 10/10 Excellent "Clean, staff is very friendly and professional " [](https://expedia.ca/Coralville-Hotels-Hyatt-Regency-Coralville-Hotel-Conference-Center.h1394020.Hotel-Information) ![Travelodge by Wyndham Iowa City](https://images.trvl-media.com/lodging/1000000/20000/11600/11583/a9e29e5b_y.jpg) ### Travelodge by Wyndham Iowa City 10/10 Excellent "Clean and comfy rooms" [](https://expedia.ca/Iowa-City-Hotels-Travelodge-By-Wyndham-Iowa-City.h11583.Hotel-Information) ![Super 8 by Wyndham Iowa City/Coralville](https://images.trvl-media.com/lodging/1000000/60000/50200/50146/f407260a_y.jpg) ### Super 8 by Wyndham Iowa City/Coralville 10/10 Excellent "No hassle with check in or check out. Very friendly" [](https://expedia.ca/Coralville-Hotels-Super-8-By-Wyndham-Iowa-CityCoralville.h50146.Hotel-Information) ![SureStay Plus Hotel by Best Western Coralville Iowa City](https://images.trvl-media.com/lodging/1000000/560000/554800/554716/acd52f26_y.jpg) ### SureStay Plus Hotel by Best Western Coralville Iowa City 10/10 Excellent "Great place for the price , they offer free breakfast as well. " [](https://expedia.ca/Coralville-Hotels-SureStay-Plus-Hotel-By-Best-Western-Coralville-Iowa-City.h554716.Hotel-Information) ## Frequently asked questions ### Are you searching for a great accommodation for your luxury trip to Twain? ### What's there to see and do in Twain? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [4 Star Hotels in East Central Iowa ](https://www.expedia.ca/4Star-East-Central-Iowa-Hotels.s40-0-d6234147.Travel-Guide-Filter-Hotels) - [5 Star Hotels in East Central Iowa ](https://www.expedia.ca/5Star-East-Central-Iowa-Hotels.s50-0-d6234147.Travel-Guide-Filter-Hotels) - [5 Star Hotels in North Liberty ](https://www.expedia.ca/5Star-North-Liberty-Hotels.s50-0-d6057135.Travel-Guide-Filter-Hotels) - [Hotels near Carver-Hawkeye Arena ](https://www.expedia.ca/Carver-Hawkeye-Arena-Hotels.0-l6202621-0.Travel-Guide-Filter-Hotels) - [Hotels near Coral Ridge Mall ](https://www.expedia.ca/Coral-Ridge-Mall-Hotels.0-l6209331-0.Travel-Guide-Filter-Hotels) - 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