Title: Book the Best BOUTIQUE Hotels in Southwest Ohio in 2025 | Expedia.ca

  

[Southwest Ohio Travel Guide](https://expedia.ca/Southwest-Ohio.dx6059286)[Hotels in Southwest Ohio](https://expedia.ca/Southwest-Ohio-Hotels.d6059286.Travel-Guide-Hotels)[Vacation Rentals in Southwest Ohio](https://expedia.ca/Southwest-Ohio-Vacation-Rentals.d6059286.Travel-Guide-VacationRentals)[Flights to Southwest Ohio](https://expedia.ca/Cheap-Flights-To-Southwest-Ohio.d6059286.Travel-Guide-Flights)[Things to do in Southwest Ohio](https://expedia.ca/Things-To-Do-In-Southwest-Ohio.d6059286.Travel-Guide-Activities)[Southwest Ohio Car Rentals](https://expedia.ca/Car-Rentals-In-Southwest-Ohio.d6059286.Car-Rental-Guide)[Southwest Ohio Vacation Packages](https://expedia.ca/Southwest-Ohio.d6059286.Destination-Travel-Guides)

![Music Hall](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/197000/197206-Cincinnati.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Find Boutique Hotels in Southwest Ohio, OH

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## Check availability on Southwest Ohio Boutique Hotels

Tonight

[Oct 15 - Oct 16](https://www.expedia.ca/Hotel-Search?regionId=6059286&startDate=2025-10-15&endDate=2025-10-16&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Oct 16 - Oct 17](https://www.expedia.ca/Hotel-Search?regionId=6059286&startDate=2025-10-16&endDate=2025-10-17&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6059286&startDate=2025-10-17&endDate=2025-10-19&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6059286&startDate=2025-10-24&endDate=2025-10-26&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Top Southwest Ohio Boutique Hotels

![1 bedroom, Egyptian cotton sheets, premium bedding, in-room safe](https://images.trvl-media.com/lodging/6000000/5290000/5287100/5287002/e40ec4ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dinner and brunch served](https://images.trvl-media.com/lodging/6000000/5290000/5287100/5287002/17dd1cba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/6000000/5290000/5287100/5287002/5b64e900.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/6000000/5290000/5287100/5287002/25619903.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 21c Museum Hotel Cincinnati

Downtown Cincinnati

8.8/10

Excellent

(1007)

"Great location and atmosphere"

CA $226

CA $269 total

includes taxes & fees

Nov 9 - Nov 10

[](https://www.expedia.ca/Cincinnati-Hotels-21c-Museum-Hotel-Cincinnati.h5287002.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-29&endDate=2025-10-30&regionId=6059286&adults=2&specialized_stays_group_explore=boutique_property&sort=RECOMMENDED&openPlayBack=true)

## Top Southwest Ohio Hotel Reviews

![The Cincinnatian Hotel Curio Collection by Hilton](//images.trvl-media.com/lodging/1000000/20000/12500/12411/90dd12e1_y.jpg)

### The Cincinnatian Hotel Curio Collection by Hilton

10/10 Excellent

"Great experience "

[](https://expedia.ca/Cincinnati-Hotels-The-Cincinnatian-Hotel-Curio-Collection-By-Hilton.h12411.Hotel-Information)

![Renaissance Cincinnati Downtown Hotel](//images.trvl-media.com/lodging/8000000/7320000/7316500/7316480/8f1dcd04_y.jpg)

### Renaissance Cincinnati Downtown Hotel

10/10 Excellent

"Clean Room. Great Staff "

[](https://expedia.ca/Cincinnati-Hotels-Renaissance-Cincinnati-Downtown-Hotel.h7316480.Hotel-Information)

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