Title: Book the Best BOUTIQUE Hotels in Southwest Ohio in 2025 | Expedia.ca [Southwest Ohio Travel Guide](https://expedia.ca/Southwest-Ohio.dx6059286)[Hotels in Southwest Ohio](https://expedia.ca/Southwest-Ohio-Hotels.d6059286.Travel-Guide-Hotels)[Vacation Rentals in Southwest Ohio](https://expedia.ca/Southwest-Ohio-Vacation-Rentals.d6059286.Travel-Guide-VacationRentals)[Flights to Southwest Ohio](https://expedia.ca/Cheap-Flights-To-Southwest-Ohio.d6059286.Travel-Guide-Flights)[Things to do in Southwest Ohio](https://expedia.ca/Things-To-Do-In-Southwest-Ohio.d6059286.Travel-Guide-Activities)[Southwest Ohio Car Rentals](https://expedia.ca/Car-Rentals-In-Southwest-Ohio.d6059286.Car-Rental-Guide)[Southwest Ohio Vacation Packages](https://expedia.ca/Southwest-Ohio.d6059286.Destination-Travel-Guides) ![Music Hall](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/197000/197206-Cincinnati.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Boutique Hotels in Southwest Ohio, OH ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southwest Ohio Boutique Hotels Tonight [Sep 29 - Sep 30](https://www.expedia.ca/Hotel-Search?regionId=6059286&startDate=2025-09-29&endDate=2025-09-30&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 30 - Oct 1](https://www.expedia.ca/Hotel-Search?regionId=6059286&startDate=2025-09-30&endDate=2025-10-01&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6059286&startDate=2025-10-03&endDate=2025-10-05&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6059286&startDate=2025-10-10&endDate=2025-10-12&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Southwest Ohio Boutique Hotels ![1 bedroom, Egyptian cotton sheets, premium bedding, in-room safe](https://images.trvl-media.com/lodging/6000000/5290000/5287100/5287002/e40ec4ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dinner and brunch served](https://images.trvl-media.com/lodging/6000000/5290000/5287100/5287002/17dd1cba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/6000000/5290000/5287100/5287002/25619903.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/6000000/5290000/5287100/5287002/5b64e900.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 21c Museum Hotel Cincinnati Downtown Cincinnati 8.8/10 Excellent (1015) "Very upbeat, friendly hotel." CA $250 CA $305 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Cincinnati-Hotels-21c-Museum-Hotel-Cincinnati.h5287002.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-13&endDate=2025-10-14®ionId=6059286&adults=2&specialized_stays_group_explore=boutique_property&sort=RECOMMENDED&openPlayBack=true) ## Top Southwest Ohio Hotel Reviews ![The Cincinnatian Hotel Curio Collection by Hilton](//images.trvl-media.com/lodging/1000000/20000/12500/12411/90dd12e1_y.jpg) ### The Cincinnatian Hotel Curio Collection by Hilton 10/10 Excellent "Nice Hotel to spend the nights in a very accessible location. Great staff." [](https://expedia.ca/Cincinnati-Hotels-The-Cincinnatian-Hotel-Curio-Collection-By-Hilton.h12411.Hotel-Information) ![Renaissance Cincinnati Downtown Hotel](//images.trvl-media.com/lodging/8000000/7320000/7316500/7316480/8f1dcd04_y.jpg) ### Renaissance Cincinnati Downtown Hotel 10/10 Excellent "Within walking distance to the ballpark. Beautiful downtown hotel." 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