Title: Book the Best BOUTIQUE Hotels in Southwest Ohio in 2025 | Expedia.ca

  

[Southwest Ohio Travel Guide](https://expedia.ca/Southwest-Ohio.dx6059286)[Hotels in Southwest Ohio](https://expedia.ca/Southwest-Ohio-Hotels.d6059286.Travel-Guide-Hotels)[Vacation Rentals in Southwest Ohio](https://expedia.ca/Southwest-Ohio-Vacation-Rentals.d6059286.Travel-Guide-VacationRentals)[Flights to Southwest Ohio](https://expedia.ca/Cheap-Flights-To-Southwest-Ohio.d6059286.Travel-Guide-Flights)[Things to do in Southwest Ohio](https://expedia.ca/Things-To-Do-In-Southwest-Ohio.d6059286.Travel-Guide-Activities)[Southwest Ohio Car Rentals](https://expedia.ca/Car-Rentals-In-Southwest-Ohio.d6059286.Car-Rental-Guide)[Southwest Ohio Vacation Packages](https://expedia.ca/Southwest-Ohio.d6059286.Destination-Travel-Guides)

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# Find Boutique Hotels in Southwest Ohio, OH

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## Check availability on Southwest Ohio Boutique Hotels

Tonight

[Sep 29 - Sep 30](https://www.expedia.ca/Hotel-Search?regionId=6059286&startDate=2025-09-29&endDate=2025-09-30&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Sep 30 - Oct 1](https://www.expedia.ca/Hotel-Search?regionId=6059286&startDate=2025-09-30&endDate=2025-10-01&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6059286&startDate=2025-10-03&endDate=2025-10-05&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6059286&startDate=2025-10-10&endDate=2025-10-12&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Top Southwest Ohio Boutique Hotels

![1 bedroom, Egyptian cotton sheets, premium bedding, in-room safe](https://images.trvl-media.com/lodging/6000000/5290000/5287100/5287002/e40ec4ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dinner and brunch served](https://images.trvl-media.com/lodging/6000000/5290000/5287100/5287002/17dd1cba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/6000000/5290000/5287100/5287002/25619903.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/6000000/5290000/5287100/5287002/5b64e900.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 21c Museum Hotel Cincinnati

Downtown Cincinnati

8.8/10

Excellent

(1015)

"Very upbeat, friendly hotel."

CA $250

CA $305 total

includes taxes & fees

Oct 12 - Oct 13

[](https://www.expedia.ca/Cincinnati-Hotels-21c-Museum-Hotel-Cincinnati.h5287002.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-13&endDate=2025-10-14&regionId=6059286&adults=2&specialized_stays_group_explore=boutique_property&sort=RECOMMENDED&openPlayBack=true)

## Top Southwest Ohio Hotel Reviews

![The Cincinnatian Hotel Curio Collection by Hilton](//images.trvl-media.com/lodging/1000000/20000/12500/12411/90dd12e1_y.jpg)

### The Cincinnatian Hotel Curio Collection by Hilton

10/10 Excellent

"Nice Hotel to spend the nights in a very accessible location. Great staff."

[](https://expedia.ca/Cincinnati-Hotels-The-Cincinnatian-Hotel-Curio-Collection-By-Hilton.h12411.Hotel-Information)

![Renaissance Cincinnati Downtown Hotel](//images.trvl-media.com/lodging/8000000/7320000/7316500/7316480/8f1dcd04_y.jpg)

### Renaissance Cincinnati Downtown Hotel

10/10 Excellent

"Within walking distance to the ballpark. Beautiful downtown hotel."

[](https://expedia.ca/Cincinnati-Hotels-Renaissance-Cincinnati-Downtown-Hotel.h7316480.Hotel-Information)

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