Title: Book the Best ADVENTURE Hotels in Southeast Missouri in 2025 | Expedia.ca [Southeast Missouri Travel Guide](https://expedia.ca/Southeast-Missouri.dx6058763)[Hotels in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels)[Vacation Rentals in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Vacation-Rentals.d6058763.Travel-Guide-VacationRentals)[Flights to Southeast Missouri](https://expedia.ca/Cheap-Flights-To-Southeast-Missouri.d6058763.Travel-Guide-Flights)[Things to do in Southeast Missouri](https://expedia.ca/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities)[Southeast Missouri Car Rentals](https://expedia.ca/Car-Rentals-In-Southeast-Missouri.d6058763.Car-Rental-Guide)[Southeast Missouri Vacation Packages](https://expedia.ca/Southeast-Missouri.d6058763.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/9/6538ce9b088c58039b33a5fe701e7a1f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels & Resorts for Couples in Southeast Missouri, MO - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southeast Missouri Hotels & Resorts for Couples Tonight [Oct 31 - Nov 1](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-10-31&endDate=2025-11-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 1 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-11-01&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Southeast Missouri Hotels & Resorts for Couples ![Front of property](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/4071c448.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/0c1d1e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/136440e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children's play area - outdoor](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/104061b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Echo Bluff State Park Eminence 9.4/10 Exceptional (211) "Beautiful location & very friendly staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Becky CA $197 CA $209 total includes taxes & fees Nov 12 - Nov 13 [](https://www.expedia.ca/Rolla-Hotels-Echo-Bluff-State-Park.h15487684.Hotel-Information) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/d2862bfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/cde4423c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/94d9e92f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/074a1dfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Charleston - Sikeston Charleston 6.8/10 (406) "I consistently choose to stay there due to positive past encounters." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) IMTIAZ CA $92 CA $102 total includes taxes & fees Nov 12 - Nov 13 [](https://www.expedia.ca/Sikeston-Hotels-Quality-Inn-Charleston-I-57.h20594.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/5600/5523/219ce8d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/10000/5600/5523/e3ed601e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/5600/5523/3c01baef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, pillowtop beds, desk](https://images.trvl-media.com/lodging/1000000/10000/5600/5523/08dfd54e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Festus Festus 6.8/10 (905) "Room dirty, mirror cracked all the way down, shelf for towels hanging by one arm so no place for towels, stinky, pool to cold to get in and dirty." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amanda CA $113 CA $129 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Festus-Hotels-Baymont-By-Wyndham-Festus.h5523.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/109000000/108970000/108967900/108967867/0846a92b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/109000000/108970000/108967900/108967867/70c9d97e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/109000000/108970000/108967900/108967867/e24e89df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/109000000/108970000/108967900/108967867/c530a526.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 2-bedroom house with AC, WiFi in serene Van Buren Van Buren 9.0/10 Wonderful (15) "It was such a cute little hidden gem! So close to everything but tucked away! Loved sitting on the back porch visiting with the owner’s chickens and sweet dogs. Would definitely stay here again! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Trina P. CA $98 CA $234 total includes taxes & fees Nov 10 - Nov 11 [](https://www.expedia.ca/Van-Buren-Hotels-Charming-2-Bedroom-House-With-AC.h108967867.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/89000000/88620000/88611700/88611645/69561cb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/89000000/88620000/88611700/88611645/78bb621e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/89000000/88620000/88611700/88611645/90-cbee2cba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/89000000/88620000/88611700/88611645/afc944e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cute and comfy bedroom with 1 queen bed/private bath Eminence 9.4/10 Exceptional (21) "Very nice, my only complaint is the shower is very small, but otherwise an affordable location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Zachary R. CA $132 CA $173 total includes taxes & fees Nov 1 - Nov 2 [](https://www.expedia.ca/Eminence-Hotels-Cute-And-Comfy-1-Bedroom-With-1-Queen-Bedprivate-Bath.h88611645.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/74000000/73280000/73274700/73274691/664fb1e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/74000000/73280000/73274700/73274691/af94ed61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/74000000/73280000/73274700/73274691/c0dd14ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/74000000/73280000/73274700/73274691/d9341c45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 82 Acre Hobby Farm with Lincoln Log Cabin De Soto 10/10 Exceptional (40) "Me an my wife visited for a staycation was very happy with the listing." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paden H. CA $199 CA $372 total includes taxes & fees Nov 1 - Nov 2 [](https://www.expedia.ca/De-Soto-Hotels-82-Acre-Hobby-Farm-With-Lincoln-Log-Cabin.h73274691.Hotel-Information) ![1 bedroom, iron/ironing board, bed sheets](https://images.trvl-media.com/lodging/24000000/23140000/23139500/23139432/86d734a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/24000000/23140000/23139500/23139432/81907571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/24000000/23140000/23139500/23139432/f03e39eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, DVD player, video library](https://images.trvl-media.com/lodging/24000000/23140000/23139500/23139432/17e1434d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beautiful Modern Loft In Wine Country! Ste. Genevieve 10/10 Exceptional (268) "The perfect escape from the city! Gorgeous views of the country while enjoying our morning coffee. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melissa L. CA $207 CA $253 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Ste-Genevieve-Hotels-Beautiful-Modern-Loft-In-Wine-Country.h23139432.Hotel-Information) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/113000000/112020000/112017900/112017805/71c262d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/113000000/112020000/112017900/112017805/055f4f65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/113000000/112020000/112017900/112017805/w2098h1398x2y0-ee5ff79b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/113000000/112020000/112017900/112017805/a7c4cf22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Johnson's Shut-ins State Park Middle Brook CA $390 CA $413 total includes taxes & fees Nov 13 - Nov 14 [](https://www.expedia.ca/Johnsons-Shut-Ins-State-Park.h112017805.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/105000000/104080000/104070800/104070754/dc9898b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/105000000/104080000/104070800/104070754/4b615244.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/105000000/104080000/104070800/104070754/0b6b722c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/105000000/104080000/104070800/104070754/2c7671ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Morning Glory - Country Cottage Piggott 10/10 Exceptional (2) "Great stay. Home was just as advertised. Great communication with owner. Will visit again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scott C. CA $179 CA $335 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/The-Morning-Glory-Country-Cottage.h104070754.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/119000000/118210000/118202500/118202492/d475c4d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/119000000/118210000/118202500/118202492/db6e85dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/119000000/118210000/118202500/118202492/fb53c0b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/119000000/118210000/118202500/118202492/84b74ee3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilltop House #2 Van Buren 9.0/10 Wonderful (2) "Very clean and nice. Not far from the river and places to eat. Would 100% stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) McKenzie W. CA $220 CA $349 total includes taxes & fees Nov 6 - Nov 7 [](https://www.expedia.ca/Van-Buren-Hotels-Hilltop-House-2.h118202492.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-14&endDate=2025-11-15®ionId=6058763&adults=2&nearby_group=recreation&sort=RECOMMENDED&openPlayBack=true) ## Top Southeast Missouri Hotel Reviews ![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](//images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG 10/10 Excellent "We had a great overnight stay to see SEMO play TSU! The hotel was great! No issues whatsoever." [](https://expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Baymont by Wyndham Festus](//images.trvl-media.com/lodging/1000000/10000/5600/5523/5f8a3296_y.jpg) ### Baymont by Wyndham Festus 10/10 Excellent "Great place to stay " [](https://expedia.ca/Festus-Hotels-Baymont-By-Wyndham-Festus.h5523.Hotel-Information) ## Frequently asked questions ### How much do hotels for couples in Southeast Missouri cost? > Hotels for couples in Southeast Missouri range between and per night. This gives you quality time with your sweetheart at a price that doesn't break the bank. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply. ### How many hotels for couples are there in Southeast Missouri? > There are hotels for couples in Southeast Missouri. Whether you're on the lookout for somewhere affordable to spend a weekend together or a luxurious romantic getaway, you'll find the perfect stay with Expedia in a few easy clicks. ### What are the best cheap hotels for couples in Southeast Missouri? > Save on your romantic Southeast Missouri getaway by reserving hotels for couples starting from per night. Preparing to discover the sights and sounds of Cape Girardeau? Unpack your bags at [Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel](https://www.expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information), a cheap option with a swimming pool and pillow top mattresses. If you're headed to Sikeston, [Pear Tree Inn Sikeston](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Sikeston.h19205.Hotel-Information) is a superb choice. Take advantage of amenities like a swimming pool and blackout curtains, and enjoy that all-important alone time together. Like to do some sightseeing in Southeast Missouri without breaking your budget? Add some major free attractions to your to-do list, like [Hunter Valley Winery](https://www.expedia.ca/Hunter-Valley-Winery-Cape-Girardeau.d553248621532655783.Vacation-Attraction) in Cape Girardeau. Sikeston also has many things to do that won't cost a penny, including [Sikeston Depot Museum](https://www.expedia.ca/Sikeston-Depot-Museum-Sikeston.d6305602.Vacation-Attraction). This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply. ### Why book your hotel for couples in Southeast Missouri with Expedia? > Expedia has some superb hotels for couples, so go ahead and indulge yourselves in Southeast Missouri. If you need to stick to a budget, select how much you'd like to spend and your preferred hotel star rating. Whatever your vacay looks like, we'll help you find a property that'll please both your pocket and partner! ### How can I find cheap hotels for couples in Southeast Missouri? > With Expedia's useful filter tool, scoring cheap hotels for couples in Southeast Missouri couldn't be simpler. To find accommodations that'll make your pocket and partner smile, refine your search by budget, star rating and amenities. ### What is there to do in Southeast Missouri near my hotel for couples? > Whether you're passionate about shopping, sightseeing, relaxation or adventure, Southeast Missouri promises something for everyone! The popular city of Cape Girardeau has lots of activities and attractions, including [Isle Casino Cape Girardeau](https://www.expedia.ca/Isle-Casino-Cape-Girardeau-Cape-Girardeau.d553248621532655780.Vacation-Attraction), [Cape Rock Park](https://www.expedia.ca/Cape-Rock-Park-Cape-Girardeau.d553248621532655781.Vacation-Attraction) and [Fort D Historic Site](https://www.expedia.ca/Fort-D-Historic-Site-Cape-Girardeau.d553248621532655775.Vacation-Attraction). If you're escaping to Ste Genevieve, [Sainte Genevieve Winery](https://www.expedia.ca/Sainte-Genevieve-Winery-Ste-Genevieve.d553248621532648574.Vacation-Attraction), [Bolduc House Museum](https://www.expedia.ca/Bolduc-House-Museum-Ste-Genevieve.d553248621532648575.Vacation-Attraction) and [Felix Valle House State Historic Site](https://www.expedia.ca/Felix-Valle-House-State-Historic-Site-Ste-Genevieve.d553248621532648573.Vacation-Attraction) are must-do's. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [Cheap Hotels in Advance](https://www.expedia.ca/Advance-Hotels-Cheap-Hotels.0-0-d553248634983475122-tCheapHotels.Travel-Guide-Filter-Hotels) - [B&B in Annapolis](https://www.expedia.ca/Annapolis-Bed-And-Breakfast.d6282465-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Hotels with Balconies in Annapolis](https://www.expedia.ca/Annapolis-Hotels-Hotels-With-Balconies.0-0-d6282465-tHotelswithBalconies.Travel-Guide-Filter-Hotels) - 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