Find Historic Hotels in Southeast Missouri, MO

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Southeast Missouri Historic Hotels

Top Southeast Missouri Historic Hotels

⚜️Rivertown Retreat⚜️ Lewis & Clark: King Bed Sleeps 4
Fridge, microwave, oven, stovetop

⚜️Rivertown Retreat⚜️ Lewis & Clark: King Bed Sleeps 4

2.0 star property
9.8 out of 10, Exceptional, (8)
"Amazing property super quiet and chill."
The price is CA $167
CA $298 total
includes taxes & fees
Aug 13 - Aug 14
⚜️Rivertown Retreat⚜️ Lewis & Clark: King Bed Sleeps 4
Beautiful Modern Loft In Wine Country!
1 bedroom, iron/ironing board, bed sheets

Beautiful Modern Loft In Wine Country!

10.0 out of 10, Exceptional, (261)
"Perfect location for a quiet getaway "
The price is CA $204
CA $249 total
includes taxes & fees
Aug 13 - Aug 14
Beautiful Modern Loft In Wine Country!
"Little Brick House on Main (1865)”
Exterior detail

"Little Brick House on Main (1865)”

10.0 out of 10, Exceptional, (50)
"The property is a lovely little house, close to places to eat and attractions. "
The price is CA $182
CA $237 total
includes taxes & fees
Aug 31 - Sep 1
"Little Brick House on Main (1865)”
Cozy Haven Little Hidden Gem Sleeps 4
Interior

Cozy Haven Little Hidden Gem Sleeps 4

9.8 out of 10, Exceptional, (46)
"There to play baseball but able to walk to downtown and enjoy some of Ste Gen. Great spot for me and my son to stay!"
The price is CA $135
CA $285 total
includes taxes & fees
Aug 12 - Aug 13
Cozy Haven Little Hidden Gem Sleeps 4
The Weber Farm - Enjoy a beautiful 100 acre farm!
Property grounds

The Weber Farm - Enjoy a beautiful 100 acre farm!

10.0 out of 10, Exceptional, (30)
"Hosts were great. I just wish they had a second bath or atleast a larger bathroom. "
The price is CA $155
CA $254 total
includes taxes & fees
Aug 12 - Aug 13
The Weber Farm - Enjoy a beautiful 100 acre farm!
Doves Nest Guest House<br> Tranquil & Relaxing
Outdoor dining

Doves Nest Guest House<br> Tranquil & Relaxing

10.0 out of 10, Exceptional, (41)
"Communication with the owners was top notch. Loved being able to walk to town and explore the historic places. "
The price is CA $177
CA $317 total
includes taxes & fees
Aug 17 - Aug 18
Doves Nest Guest House<br> Tranquil & Relaxing
Serenity South -- Gardens, River-Views, and Refreshing Space
Fridge, microwave, oven, stovetop

Serenity South -- Gardens, River-Views, and Refreshing Space

10.0 out of 10, Exceptional, (139)
"The property was exactly as listed with so many little touches that made it special. Communication was great and we were close to downtown shops and the casino. We will definitely stay again when we are in the area."
The price is CA $206
CA $337 total
includes taxes & fees
Aug 12 - Aug 13
Serenity South -- Gardens, River-Views, and Refreshing Space
Contemporary Glamping with Native American Appeal
Terrace/patio

Contemporary Glamping with Native American Appeal

9.8 out of 10, Exceptional, (150)
"The cabin was cozy, nicely appointed, and very close to the hiking trails that we were interested in. The beds were comfy, the linens in bed and bath were high quality. The hot tub was awesome!"
The price is CA $206
CA $391 total
includes taxes & fees
Aug 12 - Aug 13
Contemporary Glamping with Native American Appeal
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Exterior

Rest, Relax and Renew. Our log cabin experience awaits your arrival.

10.0 out of 10, Exceptional, (390)
"Gorgeous and comfortable property with front porch and back deck. "
The price is CA $161
CA $277 total
includes taxes & fees
Aug 13 - Aug 14
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Charming cottage overlooking Lake Acre
Exterior

Charming cottage overlooking Lake Acre

10.0 out of 10, Exceptional, (95)
"So Clean, Comfy and Serene!! Worth the drive for solitude."
The price is CA $186
CA $386 total
includes taxes & fees
Aug 14 - Aug 15
Charming cottage overlooking Lake Acre
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Southeast Missouri Hotel Reviews

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

10/10 Excellent
"Room was clean and spacious. A/C worked great. Water pressure was very good. Breakfast was ok, the waffles were very good. Plenty of parking. The owners live on site and are a very nice family and work really hard to take care of the place! "
Ryan 3-night trip
Posted 2 days ago
Baymont Inn and Suites by Wyndham Farmington, MO