Title: Book the Best SHOPPING Hotels in Southeast Missouri in 2025 | Expedia.ca [Southeast Missouri Travel Guide](https://expedia.ca/Southeast-Missouri.dx6058763)[Hotels in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels)[Vacation Rentals in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Vacation-Rentals.d6058763.Travel-Guide-VacationRentals)[Flights to Southeast Missouri](https://expedia.ca/Cheap-Flights-To-Southeast-Missouri.d6058763.Travel-Guide-Flights)[Things to do in Southeast Missouri](https://expedia.ca/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities)[Southeast Missouri Car Rentals](https://expedia.ca/Car-Rentals-In-Southeast-Missouri.d6058763.Car-Rental-Guide)[Southeast Missouri Vacation Packages](https://expedia.ca/Southeast-Missouri.d6058763.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/9/6538ce9b088c58039b33a5fe701e7a1f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Shopping Hotels in Southeast Missouri, MO ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southeast Missouri Shopping Hotels Tonight [Oct 27 - Oct 28](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-10-27&endDate=2025-10-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 28 - Oct 29](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-10-28&endDate=2025-10-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Southeast Missouri Shopping Hotels ![Free daily full breakfast](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/b92f19d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/13d95c8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/ed042ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Sikeston Sikeston 8.4/10 Very good (1015) "Very convenient and great breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Duwaine CA $118 CA $134 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/48000000/47040000/47039600/47039515/708e4b63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room](https://images.trvl-media.com/lodging/48000000/47040000/47039600/47039515/fe7ea7ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/48000000/47040000/47039600/47039515/3b9c0313.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children's play area - outdoor](https://images.trvl-media.com/lodging/48000000/47040000/47039600/47039515/a1c79fe4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Current River Inn Van Buren 8.2/10 Very good (162) "The mattresses were fabulous. Clean rooms and friendly staff. We will stay here again. The antique store and restaurants are walking distance. Nice family friendly establishment!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thad CA $122 CA $133 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Van-Buren-Hotels-Current-River-Inn.h47039515.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/107000000/106410000/106406100/106406059/5b688022.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/107000000/106410000/106406100/106406059/877e8abc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/107000000/106410000/106406100/106406059/d1f3492c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/107000000/106410000/106406100/106406059/b64100e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### "The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington Farmington 10/10 Exceptional (10) "This is a darling house and very comfortable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie B. CA $169 CA $324 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Farmington-Hotels-The-Hideaway-1-Charming-2-Bedroom-House-With-WiFi.h106406059.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/74000000/73280000/73274700/73274691/664fb1e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/74000000/73280000/73274700/73274691/d9341c45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/74000000/73280000/73274700/73274691/ee42fe11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/74000000/73280000/73274700/73274691/c0dd14ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 82 Acre Hobby Farm with Lincoln Log Cabin De Soto 10/10 Exceptional (40) "We absolutely loved our stay! The property is as listed and super clean. The owner was very easy to work with, considerate and the personal touches she provided put our stay over the top." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marshall S. CA $199 CA $373 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/De-Soto-Hotels-82-Acre-Hobby-Farm-With-Lincoln-Log-Cabin.h73274691.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/89000000/88620000/88611700/88611645/69561cb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/89000000/88620000/88611700/88611645/90-cbee2cba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/89000000/88620000/88611700/88611645/33842663.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/89000000/88620000/88611700/88611645/78bb621e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cute and comfy bedroom with 1 queen bed/private bath Eminence 9.4/10 Exceptional (19) "Rebecca has a beautiful property, clean, pretty, and conveniently located." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karla E. CA $133 CA $173 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/Eminence-Hotels-Cute-And-Comfy-1-Bedroom-With-1-Queen-Bedprivate-Bath.h88611645.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/20000000/19260000/19252900/19252851/066095c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/20000000/19260000/19252900/19252851/108eb25b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/20000000/19260000/19252900/19252851/35a75be2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/20000000/19260000/19252900/19252851/2dad0af1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Loft Apartment Across From Semo University Houch Field House. Walk To Events Cape Girardeau 10/10 Exceptional (92) "Place is spacious and was great for a weekend in Cape. Walkable to nearby restaurants." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Myles O. CA $210 CA $258 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Cape-Girardeau-Hotels-Loft-Apartment-Across-From-Semo-University-Houch-Field-House-Walk-To-Events.h19252851.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/90000000/89710000/89701300/89701234/de7e2348.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89710000/89701300/89701234/10599a29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89710000/89701300/89701234/7b7b54ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89710000/89701300/89701234/d1a4afba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Secluded in the woods, couple’s romantic cabin & hot tub, brkfast foods provided Greenville 10/10 Exceptional (4) "Cute, cozy, private getaway that you won't want to leave!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jade G. CA $213 CA $340 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Secluded-In-The-Woods.h89701234.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/106000000/105790000/105790000/105789927/85b01dbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/106000000/105790000/105790000/105789927/da6816e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/106000000/105790000/105790000/105789927/87e0f8d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels, soap, shampoo](https://images.trvl-media.com/lodging/106000000/105790000/105790000/105789927/f6efa042.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mountain View at Pickle & Perk Ironton 10/10 Exceptional (12) "Very cute place in beautiful area. Easy check-in, clean home, and comfy bed. The coffee shop below was really good with a beautiful patio. Location was perfect to access Elephant Rocks, Johnson Shut-ins, and Taum Sauk Mountain parks. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amber S. CA $200 CA $283 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Ironton-Hotels-Mountain-View-At-Pickle-Perk.h105789927.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/105000000/104080000/104070800/104070754/dc9898b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/105000000/104080000/104070800/104070754/0b6b722c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/105000000/104080000/104070800/104070754/31e53afa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/105000000/104080000/104070800/104070754/4b615244.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Morning Glory - Country Cottage Piggott 10/10 Exceptional (2) "Great stay. Home was just as advertised. Great communication with owner. Will visit again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scott C. CA $179 CA $339 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/The-Morning-Glory-Country-Cottage.h104070754.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/101000000/100470000/100465300/100465272/0cb5c163.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/101000000/100470000/100465300/100465272/w1024h570x0y56-1ec5791d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/101000000/100470000/100465300/100465272/w1024h570x0y57-36b84305.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100470000/100465300/100465272/w1024h570x0y57-17016e83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Your home away from home in downtown, historic Farmington! Farmington 10/10 Exceptional (35) "Great place to rest a recoup for weekend activities " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matt B. CA $162 CA $302 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/Farmington-Hotels-Your-Home-Away-From-Home-In-Downtown.h100465272.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-10&endDate=2025-11-11®ionId=6058763&adults=2&location_highlights_explore=shopping&sort=RECOMMENDED&openPlayBack=true) ## Top Southeast Missouri Hotel Reviews ![Pear Tree Inn Cape Girardeau West](//images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg) ### Pear Tree Inn Cape Girardeau West 10/10 Excellent "Great stay" [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](//images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "There was no milk at breakfast. When the staff said they have none available " [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Pear Tree Inn Cape Girardeau Near the Medical Center](//images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg) ### Pear Tree Inn Cape Girardeau Near the Medical Center 10/10 Excellent "Always enjoy our stay. Staff is very friendly, especially at breakfast! " [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Candlewood Suites Cape Girardeau by IHG](//images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85_y.jpg) ### Candlewood Suites Cape Girardeau by IHG 10/10 Excellent "We have been coming to Cape for the past 4 years. We have a kid going to SEMO. Everytime we come this is our spot. This is our go to "PERFECT SPOT". Great location for everything and Great Staff." [](https://expedia.ca/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information) ![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](//images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG 10/10 Excellent "We had a great overnight stay to see SEMO play TSU! The hotel was great! No issues whatsoever." [](https://expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Quality Inn](//images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781_y.jpg) ### Quality Inn 10/10 Excellent "Great place with great employees" [](https://expedia.ca/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![Comfort Inn Festus - St Louis South](//images.trvl-media.com/lodging/1000000/50000/40200/40138/3ea7ebcc_y.jpg) ### Comfort Inn Festus - St Louis South 10/10 Excellent " Mika went above and beyond even getting us ice when we checked in. As I was checking out Gary fell out used.Mika got him up and inside. Got ice and bandages. We were soon on our way." [](https://expedia.ca/Farmington-Hotels-Comfort-Inn-Festus-St-Louis-South.h40138.Hotel-Information) ![Hampton Inn Poplar Bluff](//images.trvl-media.com/lodging/10000000/9830000/9827800/9827793/2dc5e17d_y.jpg) ### Hampton Inn Poplar Bluff 10/10 Excellent "Very friendly staff " [](https://expedia.ca/Poplar-Bluff-Hotels-Hampton-Inn-Poplar-Bluff-Mo.h9827793.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - [Cheap Hotels in Advance](https://www.expedia.ca/Advance-Hotels-Cheap-Hotels.0-0-d553248634983475122-tCheapHotels.Travel-Guide-Filter-Hotels) - [B&B in Annapolis](https://www.expedia.ca/Annapolis-Bed-And-Breakfast.d6282465-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Hotels with Balconies in Annapolis](https://www.expedia.ca/Annapolis-Hotels-Hotels-With-Balconies.0-0-d6282465-tHotelswithBalconies.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Annapolis](https://www.expedia.ca/Annapolis-Hotels-Luxury-Hotel.0-0-d6282465-tLuxuryHotel.Travel-Guide-Filter-Hotels) - 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