Title: Book the Best PET FRIENDLY Hotels in Southeast Missouri, MO from CA $111 - Southeast Missouri Dog-Friendly Hotels | Expedia.ca

 

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![Mini Takes the States 2014 Road Rally Memphis to St.Louis Leg:
Moark Regional Railroad Museum
HOURS: Saturdays 1 p.m. - 4 p.m.
It was not open when I stopped by but there are a few rail cars outside. Poplar has a train rich history.
This was a cool little town to stop in and take pictures. Lot's of wall murals for some reason, and some very cool architecture. Worth the stop and be sure and enjoy a lunch at Hayden's Drive-In ! 
#MTTS2014 #minitakesthestates #go11
#train](https://images.trvl-media.com/place/9449/f87e8b74-cb32-40ea-afa8-0f245bfdc84b.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Bill Dillard

# Find Pet-friendly Hotels in Southeast Missouri, MO from CA $111

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## Check availability on Southeast Missouri Pet-friendly Hotels

Tonight

[Nov 25 - Nov 26](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-11-25&endDate=2025-11-26&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Nov 26 - Nov 27](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-11-26&endDate=2025-11-27&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-11-28&endDate=2025-11-30&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-12-05&endDate=2025-12-07&adults=2&amenities=PETS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Top Southeast Missouri Pet-friendly Hotels

![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/f737107e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/08371d9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 2 Queen Beds, Accessible, Refrigerator & Microwave (Tub)](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/0941dc05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Sikeston, MO

Sikeston

9.4/10

Exceptional

(1004)

"Clean room, great location and friendly staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mark

CA $127

CA $146 total

includes taxes & fees

Dec 23 - Dec 24

[](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/4071c448.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/136440e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Children's play area - outdoor](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/104061b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/0c1d1e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Echo Bluff State Park

Eminence

9.6/10

Exceptional

(215)

"Beautiful location…excellent service and facilities / grounds were clean and well kept."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

William

CA $209

CA $221 total

includes taxes & fees

Dec 9 - Dec 10

[](https://www.expedia.ca/Rolla-Hotels-Echo-Bluff-State-Park.h15487684.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/10000000/9830000/9827800/9827793/2dc5e17d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio, 1 King Bed, Non Smoking, Kitchenette](https://images.trvl-media.com/lodging/10000000/9830000/9827800/9827793/25677988.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/10000000/9830000/9827800/9827793/5904f90a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/10000000/9830000/9827800/9827793/f6482ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Poplar Bluff

Poplar Bluff

9.4/10

Exceptional

(791)

"Staff was kind and provided a lot of information during check out."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Shea

CA $139

CA $155 total

includes taxes & fees

Dec 21 - Dec 22

[](https://www.expedia.ca/Poplar-Bluff-Hotels-Hampton-Inn-Poplar-Bluff-Mo.h9827793.Hotel-Information)

![Breakfast, lunch, dinner served; Italian cuisine ](https://images.trvl-media.com/lodging/2000000/1230000/1222200/1222183/e91b57a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1230000/1222200/1222183/0a692e3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room](https://images.trvl-media.com/lodging/2000000/1230000/1222200/1222183/4ea0b11e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1230000/1222200/1222183/59050052.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Poplar Bluff by IHG

Poplar Bluff

8.8/10

Excellent

(693)

"Amazing place"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mladen

CA $140

CA $158 total

includes taxes & fees

Dec 21 - Dec 22

[](https://www.expedia.ca/Poplar-Bluff-Hotels-Holiday-Inn-Poplar-Bluff.h1222183.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/686f0126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/4abadc7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Sikeston

Sikeston

9.0/10

Wonderful

(430)

"Room was clean and cozy, the check in-out staff were really nice and asked about our stay as well and the breakfast was a nice variety."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Doncheial

CA $134

CA $152 total

includes taxes & fees

Dec 7 - Dec 8

[](https://www.expedia.ca/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/16f1820b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/6f9bce18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/c279dc08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

9.6/10

Exceptional

(1003)

"Very nice stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Charity

CA $127

CA $143 total

includes taxes & fees

Dec 1 - Dec 2

[](https://www.expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41600/41515/b034b164.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 2 Queen Beds, Accessible, Refrigerator & Microwave (Sofabed, 2 Rooms, Tub)](https://images.trvl-media.com/lodging/1000000/50000/41600/41515/83931306.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/50000/41600/41515/b2d719b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41600/41515/a3a28e97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Poplar Bluff

Poplar Bluff

9.2/10

Wonderful

(952)

"Delicious, well-ran breakfast and quiet peaceful hotel. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Janene

CA $133

CA $150 total

includes taxes & fees

Dec 1 - Dec 2

[](https://www.expedia.ca/Poplar-Bluff-Hotels-Drury-Inn-Suites-Poplar-Bluff.h41515.Hotel-Information)

![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/627d4131.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Snack bar](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/c1fba8f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/633eb669.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tru By Hilton Cape Girardeau

Cape Girardeau

9.6/10

Exceptional

(94)

"It was a nice stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Douglas

CA $123

CA $140 total

includes taxes & fees

Dec 7 - Dec 8

[](https://www.expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/2df4267b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/ee6292b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/da4fe5e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pear Tree Inn Cape Girardeau Near the Medical Center

Cape Girardeau

9.0/10

Wonderful

(1001)

"Nice place for a stay at a reasonable price."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Arthur

CA $99

CA $111 total

includes taxes & fees

Dec 26 - Dec 27

[](https://www.expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information)

![Fountain](https://images.trvl-media.com/lodging/40000000/39450000/39440300/39440279/9c3ffe6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/40000000/39450000/39440300/39440279/dc88ded9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin | Living area](https://images.trvl-media.com/lodging/40000000/39450000/39440300/39440279/6b9600b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin | Private kitchen](https://images.trvl-media.com/lodging/40000000/39450000/39440300/39440279/e045844c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Bullwinkles Rustic Lodge

Poplar Bluff

8.6/10

Excellent

(206)

"Great stay highly recommend "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brenden

[](https://www.expedia.ca/Poplar-Bluff-Hotels-Bullwinkles-Rustic-Lodge.h39440279.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-09&endDate=2025-12-10&regionId=6058763&adults=2&amenities=PETS&sort=RECOMMENDED&openPlayBack=true)

![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_CA_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh)

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## Top Southeast Missouri Hotel Reviews

![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg)

### Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent

"Breakfast and super Kickoff was AWESOME? love this hotel!!!"

[](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information)

![Drury Inn & Suites Jackson MO](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg)

### Drury Inn & Suites Jackson MO

10/10 Excellent

"I did not stay for breakfast, but I did have a hot dinner that was excellent. I will recommend and stay at Drury Inn's the next time I travel."

[](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information)

![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg)

### Days Inn and Suites by Wyndham Sikeston

10/10 Excellent

"This was a really great stay, which was part of my long roadtrip. The hotel was right off the interstate & wasn't too noisy. My room was pretty big which I really enjoyed! The bed was super comfy. The front desk woman was super friendly and welcoming. I was able to get Door Dash to deliver to the location so that was a plus! They had quite a lot of items for breakfast, so I was surprised about that for a Days Inn. Only thing I didn't like was lack of parking, but overall, I would definitely stay here again if I come back to the area."

[](https://expedia.ca/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information)

![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg)

### Pear Tree Inn Cape Girardeau West

10/10 Excellent

"Clean and good service "

[](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information)

![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg)

### Drury Inn & Suites Sikeston, MO

10/10 Excellent

"Staff are wonderful, kind and welcoming! The happy hour is a great way to get out of your room and socialize. Lots of yummy food and drinks. "

[](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information)

![Drury Inn & Suites Cape Girardeau](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg)

### Drury Inn & Suites Cape Girardeau

10/10 Excellent

"Great rooms, super friendly staff!"

[](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information)

![La Quinta Inn & Suites by Wyndham Festus - St. Louis South](https://images.trvl-media.com/lodging/1000000/50000/42200/42120/1887aa70_y.jpg)

### La Quinta Inn & Suites by Wyndham Festus - St. Louis South

10/10 Excellent

"Staff was very nice ans helpful. Our room was clean and pleasant. "

[](https://expedia.ca/Farmington-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Festus-St-Louis-South.h42120.Hotel-Information)

![Candlewood Suites Cape Girardeau by IHG](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85_y.jpg)

### Candlewood Suites Cape Girardeau by IHG

10/10 Excellent

"Great room"

[](https://expedia.ca/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information)

![Motel 6 Poplar Bluff, MO](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/9e93b298_y.jpg)

### Motel 6 Poplar Bluff, MO

10/10 Excellent

"Everything about our stay was in complete order; access to room was easily located; office & staff were very accommodating & room was very clean & orderly. If it is necessary to have a stay in Poplar Bluff, MO at some given time; this will be our place to stay. Thank you for inquiring, good job!!!!"

[](https://expedia.ca/Poplar-Bluff-Hotels-Motel-6-Poplar-Bluff.h15689127.Hotel-Information)

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-   [Flights to Farmington](https://www.expedia.ca/Cheap-Flights-To-Farmington.d6058764.Travel-Guide-Flights)
-   [Flights to Fredericktown](https://www.expedia.ca/Cheap-Flights-To-Fredericktown.d55114.Travel-Guide-Flights)
-   [Flights to Ironton](https://www.expedia.ca/Cheap-Flights-To-Ironton.d6053585.Travel-Guide-Flights)
-   [Flights from Belleview](https://www.expedia.ca/lp/flights/3000444413/flights-from-belleview)
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-   [Flights from Centerville](https://www.expedia.ca/lp/flights/553248634983078632/flights-from-centerville)

-   [Visit Fredericktown](https://www.expedia.ca/Fredericktown.dx55114)
-   [K Bridge Recreation Area](https://www.expedia.ca/K-Bridge-Recreation-Area-Annapolis.d6282501.Vacation-Attraction)

-   [Avis Rental Cars in Farmington](https://www.expedia.ca/Avis-Car-Rentals-In-Farmington.d6058764-c41.Car-Rental-Guide-Suppliers)
-   [Hertz Rental Cars in Marble Hill](https://www.expedia.ca/Hertz-Car-Rentals-In-Marble-Hill.d3000445212-c40.Car-Rental-Guide-Suppliers)
-   [National Car Rental Rental Cars in Fredericktown](https://www.expedia.ca/National-Car-Rental-Car-Rentals-In-Fredericktown.d55114-c42.Car-Rental-Guide-Suppliers)

-   [Marble Hill Vacation Rentals](https://www.expedia.ca/Marble-Hill-Vacation-Rentals.d3000445212.Travel-Guide-VacationRentals)

-   [Book Pet-friendly Hotels in Southeast Missouri on Expedia.com](https://www.expedia.com/Southeast-Missouri-Hotels-Pet-Friendly-Hotel.0-0-d6058763-tPetfriendlyHotel.Travel-Guide-Filter-Hotels)