Title: Book the Best Southeast Minnesota SPA Resorts - Spa Hotels in Southeast Minnesota, MN | Expedia.ca [Southeast Minnesota Travel Guide](https://expedia.ca/Southeast-Minnesota.dx6233996)[Hotels in Southeast Minnesota](https://expedia.ca/Southeast-Minnesota-Hotels.d6233996.Travel-Guide-Hotels)[Vacation Rentals in Southeast Minnesota](https://expedia.ca/Southeast-Minnesota-Vacation-Rentals.d6233996.Travel-Guide-VacationRentals)[Flights to Southeast Minnesota](https://expedia.ca/Cheap-Flights-To-Southeast-Minnesota.d6233996.Travel-Guide-Flights)[Southeast Minnesota Car Rentals](https://expedia.ca/Car-Rentals-In-Southeast-Minnesota.d6233996.Car-Rental-Guide)[Southeast Minnesota Vacation Packages](https://expedia.ca/Southeast-Minnesota.d6233996.Destination-Travel-Guides) ![Rochester showing a city and skyline](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63803-Rochester.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Southeast Minnesota, MN ### Change your mind Book hotels with free cancellation ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ### Be picky Search almost a million properties worldwide ## Check availability on Southeast Minnesota Spa Hotels Tonight [Oct 6 - Oct 7](https://www.expedia.ca/Hotel-Search?regionId=6233996&startDate=2025-10-06&endDate=2025-10-07&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 7 - Oct 8](https://www.expedia.ca/Hotel-Search?regionId=6233996&startDate=2025-10-07&endDate=2025-10-08&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6233996&startDate=2025-10-10&endDate=2025-10-12&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6233996&startDate=2025-10-17&endDate=2025-10-19&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Southeast Minnesota Spa Hotels ![Lobby](https://images.trvl-media.com/lodging/16000000/15300000/15291300/15291258/f590e78a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15300000/15291300/15291258/ffa93f1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/16000000/15300000/15291300/15291258/516cac96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/16000000/15300000/15291300/15291258/20c6a208.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grandstay Hotel and Suites Waseca 7.6/10 Good (240) "It was clean room and pleasant staff." CA $116 CA $129 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Owatonna-Hotels-Grandstay-Hotel-And-Suites.h15291258.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/200000/199000/198946/d6da8b6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby Tower Queen Room](https://images.trvl-media.com/lodging/1000000/200000/199000/198946/e5d5175b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/200000/199000/198946/61e51f32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/200000/199000/198946/0fb5698e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mystic Lake Casino Hotel Prior Lake 9.0/10 Wonderful (2265) "Great hotel and restaurants. " CA $182 CA $203 total includes taxes & fees Oct 15 - Oct 16 [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-Mystic-Lake-Casino-Hotel.h198946.Hotel-Information) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/10000/8900/8820/a6d4835a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/10000/8900/8820/8e8e2669.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/1000000/10000/8900/8820/8ed672f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Library](https://images.trvl-media.com/lodging/1000000/10000/8900/8820/1e966b86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### St James Hotel, a Historic Hotel of America Red Wing 9.2/10 Wonderful (1001) "Love the historical hotel. Very clean and the staff was great. " CA $225 CA $256 total includes taxes & fees Oct 7 - Oct 8 [](https://www.expedia.ca/Red-Wing-Hotels-St-James-Hotel.h8820.Hotel-Information) ![Walk-Out, 1 Queen Bed, Non Smoking, Jetted Tub & Fireplace (1st Floor) | Terrace/patio](https://images.trvl-media.com/lodging/2000000/1480000/1479300/1479277/24fb4c02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1480000/1479300/1479277/305ee3c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Suite, 1 Queen Bed (1st Floor) | Private spa tub](https://images.trvl-media.com/lodging/2000000/1480000/1479300/1479277/b0140aff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges](https://images.trvl-media.com/lodging/2000000/1480000/1479300/1479277/ccf52467.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Afton House Inn Afton 8.2/10 Very good (235) "Staff was incredible, very historic pace, and peaceful. " CA $213 CA $241 total includes taxes & fees Oct 7 - Oct 8 [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-Afton-House-Inn.h1479277.Hotel-Information) ![Couples treatment rooms, sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/55000000/54180000/54172300/54172209/93adc461.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, down comforters, in-room safe](https://images.trvl-media.com/lodging/55000000/54180000/54172300/54172209/90f9b86d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dinner served](https://images.trvl-media.com/lodging/55000000/54180000/54172300/54172209/06ffc248.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/55000000/54180000/54172300/54172209/91361409.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omni Viking Lakes Hotel Eagan 9.6/10 Exceptional (909) "Great property, clean, loads of amenities, and very friendly staff! " CA $222 CA $247 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-Omni-Viking-Lakes-Hotel.h54172209.Hotel-Information) ![Luxury Single Room](https://images.trvl-media.com/lodging/47000000/46990000/46980900/46980893/e51df0cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/47000000/46990000/46980900/46980893/455654ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Single Room](https://images.trvl-media.com/lodging/47000000/46990000/46980900/46980893/a183938d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/47000000/46990000/46980900/46980893/d54840be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Round Barn Farm B & B Event Center Red Wing 10/10 Exceptional (39) "Beautiful property with great hosts! Strongly recommend!" CA $306 CA $329 total includes taxes & fees Oct 14 - Oct 15 [](https://www.expedia.ca/Red-Wing-Hotels-Round-Barn-Farm-B-B-Event-Center.h46980893.Hotel-Information) ![Serves lunch, dinner, and happy hour](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/3b0f1e42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, desk](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/8d7f7147.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/493f76e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Rochester Near Mayo Clinic Rochester 8.2/10 Very good (1058) "Good place to stay " CA $103 CA $119 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/b1555778.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/f4c0d6e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/86063f91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, Multiple Beds | Living area](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/c7a0b093.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Rochester Mayo Clinic Area Downtown Rochester 9.6/10 Exceptional (516) "Great hotel and location. Will definitely select this property again for my next stay in Rochester. " CA $248 CA $285 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Rochester-Hotels-Hilton-Rochester-Mayo-Clinic-Area.h27426319.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-20&endDate=2025-10-21®ionId=6233996&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Southeast Minnesota Hotel Reviews ![Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area](//images.trvl-media.com/lodging/1000000/10000/3600/3556/b33056f7_y.jpg) ### Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area 10/10 Excellent "Easy walk to Mayo clinic! The outdoor patio was a great place to unwind after long days of appointments at the Mayo clinic." [](https://expedia.ca/Rochester-Hotels-Centerstone-Plaza-Hotel-Soldiers-FieldMayo-Clinic-Area.h3556.Hotel-Information) ![Spark by Hilton Rochester South](//images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/w3837h2557x3y3-c2ce9db3_y.jpg) ### Spark by Hilton Rochester South 10/10 Excellent "Clean room, great staff!" [](https://expedia.ca/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![Kahler Inn and Suites - Mayo Clinic Area](//images.trvl-media.com/lodging/1000000/180000/171600/171566/e56e7dae_y.jpg) ### Kahler Inn and Suites - Mayo Clinic Area 10/10 Excellent "Clean and friendly. Very good breakfast " [](https://expedia.ca/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S](//images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353_y.jpg) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S 10/10 Excellent "well kept great staff " [](https://expedia.ca/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![Kahler Grand Hotel](//images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg) ### Kahler Grand Hotel 10/10 Excellent "There’s a lot of street work in progress around the hotel right now; but the inconvenience is manageable. You can’t beat the price and convenience for proximity and accessibility to the Mayo Clinic. " [](https://expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![Express Suites Riverport Inn & Suites](//images.trvl-media.com/lodging/1000000/20000/11700/11603/dccd832e_y.jpg) ### Express Suites Riverport Inn & Suites 10/10 Excellent "The staff was awesome. The pool area was great, the room was comfortable, very nice." [](https://expedia.ca/Winona-Hotels-Express-Suites-Riverport-Inn-Suites.h11603.Hotel-Information) ![St James Hotel, a Historic Hotel of America](//images.trvl-media.com/lodging/1000000/10000/8900/8820/c90b9231_y.jpg) ### St James Hotel, a Historic Hotel of America 10/10 Excellent "My family stayed in several rooms here for a mini family reunion and we all had a great experience. Everyone at the front desk was friendly and went out of their way to help us. My room had a lovely view of the river. We all enjoyed looking at the historical exhibits around the hotel. Red Wing is a cute town too." [](https://expedia.ca/Red-Wing-Hotels-St-James-Hotel.h8820.Hotel-Information) ![Hampton Inn Rochester-South](//images.trvl-media.com/lodging/1000000/20000/16600/16522/f90bd051_y.jpg) ### Hampton Inn Rochester-South 10/10 Excellent "Staff was friendly and helpful. Beds were super comfortable. Breakfast was awesome!" [](https://expedia.ca/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information) ![Med City Inn & Suites - Mayo Clinic Area](//images.trvl-media.com/lodging/1000000/10000/4200/4106/4b21fb74_y.jpg) ### Med City Inn & Suites - Mayo Clinic Area 10/10 Excellent "This is one of the best hotels I've ever stayed in.b" [](https://expedia.ca/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [4 Star Hotels in Northwest](https://www.expedia.ca/4Star-Northwest-Rochester-Hotels.s40-n900102874825277440-0.Travel-Guide-Filter-Hotels) - [Hotels near Apache Mall](https://www.expedia.ca/Apache-Mall-Hotels.0-l6188936-0.Travel-Guide-Filter-Hotels) - [Farmstay in Byron](https://www.expedia.ca/Byron-Agritourism.d553248623858895563-aaAgritourism.Travel-Guide-Accommodation) - [Aparthotels in Byron](https://www.expedia.ca/Byron-Apart-Hotels.d553248623858895563-aaApartHotels.Travel-Guide-Accommodation) - 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