Title: Book the Best Southeast Minnesota LUXURY Hotels - Upscale Hotels in Southeast Minnesota, MN | Expedia.ca [Southeast Minnesota Travel Guide](https://expedia.ca/Southeast-Minnesota.dx6233996)[Hotels in Southeast Minnesota](https://expedia.ca/Southeast-Minnesota-Hotels.d6233996.Travel-Guide-Hotels)[Vacation Rentals in Southeast Minnesota](https://expedia.ca/Southeast-Minnesota-Vacation-Rentals.d6233996.Travel-Guide-VacationRentals)[Flights to Southeast Minnesota](https://expedia.ca/Cheap-Flights-To-Southeast-Minnesota.d6233996.Travel-Guide-Flights)[Southeast Minnesota Car Rentals](https://expedia.ca/Car-Rentals-In-Southeast-Minnesota.d6233996.Car-Rental-Guide)[Southeast Minnesota Vacation Packages](https://expedia.ca/Southeast-Minnesota.d6233996.Destination-Travel-Guides) ![Rochester showing a city and skyline](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63803-Rochester.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Southeast Minnesota, MN ### Change your mind Book hotels with free cancellation ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ### Be picky Search almost a million properties worldwide ## Check availability on Southeast Minnesota Luxury Hotels Tonight [Oct 7 - Oct 8](https://www.expedia.ca/Hotel-Search?regionId=6233996&startDate=2025-10-07&endDate=2025-10-08&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 8 - Oct 9](https://www.expedia.ca/Hotel-Search?regionId=6233996&startDate=2025-10-08&endDate=2025-10-09&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6233996&startDate=2025-10-10&endDate=2025-10-12&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6233996&startDate=2025-10-17&endDate=2025-10-19&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Southeast Minnesota Luxury Hotels ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/ecda08e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/86c17899.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms | Living area](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/45535621.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kahler Grand Hotel Downtown Rochester 8.2/10 Very good (1642) "Great location, beautiful hotel!" CA $169 CA $195 total includes taxes & fees Nov 6 - Nov 7 [](https://www.expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/4b21fb74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 indoor pools](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/6897f3e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/f8e4d672.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/f78e7c09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Med City Inn & Suites - Mayo Clinic Area Kutzky Park 7.8/10 Good (1001) "Good location " CA $101 CA $116 total includes taxes & fees Oct 8 - Oct 9 [](https://www.expedia.ca/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/9000000/8150000/8145400/8145327/f7403b77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/9000000/8150000/8145400/8145327/9f9116a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/9000000/8150000/8145400/8145327/416983a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/9000000/8150000/8145400/8145327/90ab369f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Northfield Northfield 8.2/10 Very good (612) "Loved the lobby area and the staff were very kind and friendly. Breakfast was good with a variety of choices. The pool and hot tub were also a welcome addition! I will definitely be staying here again. " CA $141 CA $156 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Owatonna-Hotels-AmericInn-By-Wyndham-Northfield.h8145327.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/460000/459800/459757/f9d660c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, designer toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/460000/459800/459757/c00e3044.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/460000/459800/459757/39bea812.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/459800/459757/c50d2d73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Coratel Inn & Suites By Jasper Northfield Northfield 6.2/10 (624) "Very nice place to stay." CA $84 CA $93 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Owatonna-Hotels-Coratel-Inn-Suites-Northfield.h459757.Hotel-Information) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/e56e7dae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/053999c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 7:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/41a1c74b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV, pay movies](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/9d7d5e02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kahler Inn and Suites - Mayo Clinic Area Downtown Rochester 8.0/10 Very good (1453) "Pleasant stay" CA $160 CA $185 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/f77375e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/a518fccf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/abb2c83e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Brentwood Inn & Suites Downtown Rochester 8.8/10 Excellent (1000) "This hotel is very convenient and affordable for appointments at Mayo. " CA $157 CA $181 total includes taxes & fees Oct 9 - Oct 10 [](https://www.expedia.ca/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25400/25338/046c7ce7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/25400/25338/71dead3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25400/25338/ceaab958.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/25400/25338/95539a8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Winona Winona 7.8/10 Good (1003) "The room was very nice, bed was very comfortable, and the staff friendly." CA $95 CA $106 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Winona-Hotels-Days-Inn-By-Wyndham-Winona.h25338.Hotel-Information) ![Standard Room, 1 Queen Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/43500/43416/c82aecae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/43500/43416/2bd6f3e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/43500/43416/c992fc57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/50000/43500/43416/90117589.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Regency Inn & Suites Faribault 7.4/10 Good (621) "It was a fine place to stay, conveniently right off the highway. " CA $96 CA $123 total includes taxes & fees Oct 8 - Oct 9 [](https://www.expedia.ca/Owatonna-Hotels-Regency-Inn-Suites.h43416.Hotel-Information) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/3000000/2790000/2784600/2784519/7f955511.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/3000000/2790000/2784600/2784519/a0fb3319.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/3000000/2790000/2784600/2784519/ffef9c0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/3000000/2790000/2784600/2784519/6e4e22cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Birch Hill Suite Rochester – Med City Rochester 6.4/10 (8) "I like that the property is close to the VA center where there is a bus stop. Just steps away. But this property had no phone in the room, I could not get Wyndham rewards, it's no longer they advertise free breakfast but that was not true. I" [](https://www.expedia.ca/Rochester-Hotels-Birch-Hill-Suite-Rochester-Med-City.h2784519.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/92dc90b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/25e32575.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/31690353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/fca8e68c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aspen Select Rochester 8.4/10 Very good (1003) "Clean room | Staff was helpful and friendly" CA $131 CA $158 total includes taxes & fees Oct 10 - Oct 11 [](https://www.expedia.ca/Rochester-Hotels-Aspen-Select.h12245240.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-21&endDate=2025-10-22®ionId=6233996&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top Southeast Minnesota Hotel Reviews ![Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area](//images.trvl-media.com/lodging/1000000/10000/3600/3556/b33056f7_y.jpg) ### Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area 10/10 Excellent "Easy walk to Mayo clinic! The outdoor patio was a great place to unwind after long days of appointments at the Mayo clinic." [](https://expedia.ca/Rochester-Hotels-Centerstone-Plaza-Hotel-Soldiers-FieldMayo-Clinic-Area.h3556.Hotel-Information) ![Kahler Inn and Suites - Mayo Clinic Area](//images.trvl-media.com/lodging/1000000/180000/171600/171566/e56e7dae_y.jpg) ### Kahler Inn and Suites - Mayo Clinic Area 10/10 Excellent "Clean and friendly. Very good breakfast " [](https://expedia.ca/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S](//images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353_y.jpg) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S 10/10 Excellent "well kept great staff " [](https://expedia.ca/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![Kahler Grand Hotel](//images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg) ### Kahler Grand Hotel 10/10 Excellent "There’s a lot of street work in progress around the hotel right now; but the inconvenience is manageable. You can’t beat the price and convenience for proximity and accessibility to the Mayo Clinic. " [](https://expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![St James Hotel, a Historic Hotel of America](//images.trvl-media.com/lodging/1000000/10000/8900/8820/c90b9231_y.jpg) ### St James Hotel, a Historic Hotel of America 10/10 Excellent "My family stayed in several rooms here for a mini family reunion and we all had a great experience. Everyone at the front desk was friendly and went out of their way to help us. My room had a lovely view of the river. We all enjoyed looking at the historical exhibits around the hotel. Red Wing is a cute town too." [](https://expedia.ca/Red-Wing-Hotels-St-James-Hotel.h8820.Hotel-Information) ![Med City Inn & Suites - Mayo Clinic Area](//images.trvl-media.com/lodging/1000000/10000/4200/4106/4b21fb74_y.jpg) ### Med City Inn & Suites - Mayo Clinic Area 10/10 Excellent "This is one of the best hotels I've ever stayed in.b" [](https://expedia.ca/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) ![Aspen Select](//images.trvl-media.com/lodging/13000000/12250000/12245300/12245240/92dc90b5_y.jpg) ### Aspen Select 10/10 Excellent "Mayo Clinic is across the street." [](https://expedia.ca/Rochester-Hotels-Aspen-Select.h12245240.Hotel-Information) ![SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys](//images.trvl-media.com/lodging/1000000/110000/102000/101902/39da8a7c_y.jpg) ### SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys 10/10 Excellent "Bathroom floor lifting....soaking wet under plastic flooring... smells like mold" [](https://expedia.ca/Rochester-Hotels-SpringHill-Suites-By-Marriott-Rochester-Mayo-ClinicSt-Marys.h101902.Hotel-Information) ![AmericInn by Wyndham Rochester Near Mayo Clinic](//images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30_y.jpg) ### AmericInn by Wyndham Rochester Near Mayo Clinic 10/10 Excellent "Quick and easy check in" [](https://expedia.ca/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [4 Star Hotels in Northwest](https://www.expedia.ca/4Star-Northwest-Rochester-Hotels.s40-n900102874825277440-0.Travel-Guide-Filter-Hotels) - 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[Car rental Rochester](https://www.expedia.ca/Car-Rentals-In-Rochester.d3041.Car-Rental-Guide) - [Rochester Vacation Rentals](https://www.expedia.ca/Rochester-Vacation-Rentals.d3041.Travel-Guide-VacationRentals) - [Book Luxury Hotels in Southeast Minnesota on Expedia.com](https://www.expedia.com/Southeast-Minnesota-Hotels-Luxury-Hotel.0-0-d6233996-tLuxuryHotel.Travel-Guide-Filter-Hotels)