Title: Book the Best Southeast Ohio LUXURY Hotels - Upscale Hotels in Southeast Ohio, OH | Expedia.ca [Southeast Ohio Travel Guide](https://expedia.ca/Southeast-Ohio.dx6059285)[Hotels in Southeast Ohio](https://expedia.ca/Southeast-Ohio-Hotels.d6059285.Travel-Guide-Hotels)[Vacation Rentals in Southeast Ohio](https://expedia.ca/Southeast-Ohio-Vacation-Rentals.d6059285.Travel-Guide-VacationRentals)[Flights to Southeast Ohio](https://expedia.ca/Cheap-Flights-To-Southeast-Ohio.d6059285.Travel-Guide-Flights)[Southeast Ohio Car Rentals](https://expedia.ca/Car-Rentals-In-Southeast-Ohio.d6059285.Car-Rental-Guide)[Southeast Ohio Vacation Packages](https://expedia.ca/Southeast-Ohio.d6059285.Destination-Travel-Guides) ![About all that remains of Moonville is this old railroad tunnel. The town sprang up in the late 1800's because of the Marietta and Cincinnati railroad building through the uninhabited forest on its way to Cincinnati. The coal town's population peaked at just over one hundred. The last family left town in 1947. By the 1960s most of the buildings were gone and only the tunnel survives today. The Moonville Tunnel can be accessed via The Moonville Rail-Trail, a sixteen-mile #hiking trail comprising the abandoned railway inside the Zaleski State Forest. ](https://images.trvl-media.com/place/3000453261/7814a39f-e0ab-4663-850a-611321076814.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by throwingsofas # Find luxury hotels in Southeast Ohio, OH - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southeast Ohio Luxury Hotels Tonight [Nov 28 - Nov 29](https://www.expedia.ca/Hotel-Search?regionId=6059285&startDate=2025-11-28&endDate=2025-11-29&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [Nov 29 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=6059285&startDate=2025-11-29&endDate=2025-11-30&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=6059285&startDate=2025-11-28&endDate=2025-11-30&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=6059285&startDate=2025-12-05&endDate=2025-12-07&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Top Southeast Ohio Luxury Hotels ![Ballroom](https://images.trvl-media.com/lodging/1000000/10000/6100/6032/35b37036.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Library](https://images.trvl-media.com/lodging/1000000/10000/6100/6032/bf347d2c_edited_5de6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/6100/6032/3cfe22fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/6100/6032/w489h735x4y0-922fb495.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Blennerhassett Hotel Parkersburg 9.4/10 Exceptional (1006) "Beautiful hotel and my granddaughter loved all the Christmas trees in the lobby. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rebecca CA $149 CA $174 total includes taxes & fees Dec 11 - Dec 12 [](https://www.expedia.ca/Parkersburg-Hotels-The-Blennerhassett-Hotel.h6032.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/14000000/13480000/13471700/13471606/843aa4a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/14000000/13480000/13471700/13471606/dc8b2454.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/14000000/13480000/13471700/13471606/bf3decec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/14000000/13480000/13471700/13471606/af3d421c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Garland Hotel New Concord 9.2/10 Wonderful (935) "Peaceful, quiet area and amazing rooms for the price." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sasha CA $87 CA $100 total includes taxes & fees Dec 29 - Dec 30 [](https://www.expedia.ca/New-Concord-Hotels-Garland-Hotel.h13471606.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/8600/8583/9618bbe6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/10000/8600/8583/8b407aef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds, Non Smoking, Refrigerator & Microwave | Living area](https://images.trvl-media.com/lodging/1000000/10000/8600/8583/c5484f19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/8600/8583/60c334e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Adena Inn Chillicothe 7.8/10 Good (770) "Loved breakfast ,close to restaurants, and very quite" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) karen CA $143 CA $164 total includes taxes & fees Dec 3 - Dec 4 [](https://www.expedia.ca/Chillicothe-Hotels-Best-Western-Adena-Inn.h8583.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/19000000/18720000/18711100/18711017/w1170h878x0y827-f54fdfdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/19000000/18720000/18711100/18711017/6a6cb63e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18720000/18711100/18711017/w1170h878x0y827-cd97cadc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/19000000/18720000/18711100/18711017/e802ee00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Deluxe Inn Hebron 6.8/10 (271) "Loved my stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert CA $63 CA $71 total includes taxes & fees Dec 16 - Dec 17 [](https://www.expedia.ca/Hebron-Hotels-Deluxe-Inn.h18711017.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1870000/1868900/1868803/699e3988.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1870000/1868900/1868803/261d2195.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1870000/1868900/1868803/fb50516c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/2000000/1870000/1868900/1868803/41f3474a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Granville Inn Granville 9.6/10 Exceptional (725) "It was great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Theresa M. CA $314 CA $346 total includes taxes & fees Dec 2 - Dec 3 [](https://www.expedia.ca/Zanesville-Hotels-Granville-Inn.h1868803.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/14000000/13070000/13068200/13068101/752fe927.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed](https://images.trvl-media.com/lodging/14000000/13070000/13068200/13068101/8fc7374b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/14000000/13070000/13068200/13068101/c13080ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/14000000/13070000/13068200/13068101/57dcd066.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Executive Inn Chillicothe 7.6/10 Good (642) "Great room, clean and beds and pillows super comfy! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jason CA $84 CA $97 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Chillicothe-Hotels-Executive-Inn.h13068101.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/40000/40000/39931/4a096f7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/40000/40000/39931/6420eb92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/40000/39931/w5500h3649x0y6-0804e267.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine, pool views ](https://images.trvl-media.com/lodging/1000000/40000/40000/39931/bacb3f1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ohio University Inn & Conference Center Athens 9.2/10 Wonderful (1015) "Best place to stay in Athens" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christopher CA $146 CA $166 total includes taxes & fees Nov 29 - Nov 30 [](https://www.expedia.ca/Athens-Hotels-Ohio-University-Inn-Conference-Center.h39931.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/2000000/1600000/1593300/1593237/fcc2f5e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1600000/1593300/1593237/201b67ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1600000/1593300/1593237/7f6bfbd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/2000000/1600000/1593300/1593237/dd82e9d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Athens Athens 9.2/10 Wonderful (864) "This is a very nice hotel. I would go there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deborah CA $134 CA $151 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Athens-Hotels-Hampton-Inn-Athens.h1593237.Hotel-Information) ![Executive Suite, 1 King Bed, Non Smoking, Hot Tub](https://images.trvl-media.com/lodging/1000000/160000/155900/155861/fd9d009f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/160000/155900/155861/e7449803.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/160000/155900/155861/3c4f92bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/160000/155900/155861/f1804fc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Cambridge Cambridge 8.2/10 Very good (1004) "Clean & staff was very nice. Only negative was the breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles CA $82 CA $96 total includes taxes & fees Dec 4 - Dec 5 [](https://www.expedia.ca/Zanesville-Hotels-Baymont-By-Wyndham-Cambridge.h155861.Hotel-Information) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/10000/9100/9003/4d0a03ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/10000/9100/9003/b9153f71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9100/9003/c29456d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/9100/9003/36163b70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Zanesville City Center Zanesville 7.6/10 Good (273) "We had a nice stay! The staff was friendly , the room was clean! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James CA $119 CA $136 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Zanesville-Hotels-Zane-Inn-And-Suites.h9003.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-12&endDate=2025-12-13®ionId=6059285&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_CA_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Limited-time deals: save up to 50% on select hotels [Book now](https://expedia.ca/deals?rfrr=AFFINITY_BF_PROMO_6059285) ## Top Southeast Ohio Hotel Reviews ![Americas Best Value Inn & Suites St. Clairsville Wheeling](https://images.trvl-media.com/lodging/1000000/130000/122900/122815/71c447d0_y.jpg) ### Americas Best Value Inn & Suites St. Clairsville Wheeling 10/10 Excellent "Have stayed here many times. Inexpensive, clean and great location." [](https://expedia.ca/St-Clairsville-Hotels-Americas-Best-Value-Inn-St-Clairsville-Wheeling.h122815.Hotel-Information) ![Days Inn by Wyndham Columbus East Airport](https://images.trvl-media.com/lodging/1000000/10000/4600/4541/49a8132f_y.jpg) ### Days Inn by Wyndham Columbus East Airport 10/10 Excellent "i was in a smoking room, which always makes me happy, even if i have to walk all the way round the back where our scent is out of the way. i have been contending with lots of very uncomfortable experiences lately because my physical and mental health are a struggle....deposits get sprung on me like threats and challenges....staff here was kind sa" [](https://expedia.ca/Columbus-Hotels-Days-Inn-By-Wyndham-Columbus-East-Airport.h4541.Hotel-Information) ![Ohio University Inn & Conference Center](https://images.trvl-media.com/lodging/1000000/40000/40000/39931/4a096f7d_y.jpg) ### Ohio University Inn & Conference Center 10/10 Excellent "Clean and spacious. " [](https://expedia.ca/Athens-Hotels-Ohio-University-Inn-Conference-Center.h39931.Hotel-Information) ![Quality Inn](https://images.trvl-media.com/lodging/1000000/130000/124400/124351/4aaecbd5_y.jpg) ### Quality Inn 10/10 Excellent "Very good for a quick stop, every think works, room was clean, also the hallway and restaurant. They offer coffee and juice 24 hours. The employee are polite and helpful. Is a good option if you need to stay in Athens in a Budget." [](https://expedia.ca/Athens-Hotels-Quality-Inn.h124351.Hotel-Information) ![Christopher Inn and Suites](https://images.trvl-media.com/lodging/2000000/1040000/1039700/1039674/50c4cecb_y.jpg) ### Christopher Inn and Suites 10/10 Excellent "Staff very friendly and helpful " [](https://expedia.ca/Chillicothe-Hotels-Christopher-Inn-And-Suites.h1039674.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [Hotels near Ash Cave](https://www.expedia.ca/Ash-Cave-Hotels.0-l6296751-0.Travel-Guide-Filter-Hotels) - [Ski Hotels in Columbus](https://www.expedia.ca/Columbus-Hotels-Ski-Hotel.0-0-d178251-tSkiHotel.Travel-Guide-Filter-Hotels) - [Hotels near Conkles Hollow State Nature Preserve](https://www.expedia.ca/Conkles-Hollow-State-Nature-Preserve-Hotels.0-l6296770-0.Travel-Guide-Filter-Hotels) - [B&B in Creola](https://www.expedia.ca/Creola-Bed-And-Breakfast.d3000452409-aaBedAndBreakfast.Travel-Guide-Accommodation) - 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