Title: Book the Best Southeast Iowa WINERY Hotels in 2025 | Expedia.ca [Southeast Iowa Travel Guide](https://expedia.ca/Southeast-Iowa.dx6234151)[Hotels in Southeast Iowa](https://expedia.ca/Southeast-Iowa-Hotels.d6234151.Travel-Guide-Hotels)[Vacation Rentals in Southeast Iowa](https://expedia.ca/Southeast-Iowa-Vacation-Rentals.d6234151.Travel-Guide-VacationRentals)[Flights to Southeast Iowa](https://expedia.ca/Cheap-Flights-To-Southeast-Iowa.d6234151.Travel-Guide-Flights)[Southeast Iowa Car Rentals](https://expedia.ca/Car-Rentals-In-Southeast-Iowa.d6234151.Car-Rental-Guide)[Southeast Iowa Vacation Packages](https://expedia.ca/Southeast-Iowa.d6234151.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/55b2c6dee1b7995ed1033756cd63ca06.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Winery Hotels in Southeast Iowa ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southeast Iowa Winery Hotels Tonight [Oct 14 - Oct 15](https://www.expedia.ca/Hotel-Search?regionId=6234151&startDate=2025-10-14&endDate=2025-10-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 15 - Oct 16](https://www.expedia.ca/Hotel-Search?regionId=6234151&startDate=2025-10-15&endDate=2025-10-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6234151&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6234151&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Southeast Iowa Winery Hotels ![Reception](https://images.trvl-media.com/lodging/1000000/70000/68200/68135/29eea63f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/70000/68200/68135/0665e0f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/68200/68135/4c1852e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/70000/68200/68135/f0df8156.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Mount Pleasant 7.8/10 Good (102) "Always a great place to stay with nice breakfast buffet choices !" CA $88 CA $99 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Burlington-Hotels-Quality-Inn-Suites.h68135.Hotel-Information) ![Water park](https://images.trvl-media.com/lodging/2000000/1810000/1803400/1803337/3ad09b6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1810000/1803400/1803337/c12d27ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception hall](https://images.trvl-media.com/lodging/2000000/1810000/1803400/1803337/f77198ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports bar](https://images.trvl-media.com/lodging/2000000/1810000/1803400/1803337/786c2905.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fun City Resort Hotel Burlington 8.4/10 Very good (289) "This was kid friendly and there were options for the kids and adults to be entertained. " CA $201 CA $235 total includes taxes & fees Oct 15 - Oct 16 [](https://www.expedia.ca/Burlington-Hotels-The-PZAZZ-Resort-Hotel.h1803337.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/9000000/8520000/8512100/8512062/b7f01cc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8520000/8512100/8512062/dcd82ad5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (Ellen's Orchard)](https://images.trvl-media.com/lodging/9000000/8520000/8512100/8512062/f324bf76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (Beth's Forest)](https://images.trvl-media.com/lodging/9000000/8520000/8512100/8512062/43a16142.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nauvoo Grand Bed & Breakfast Nauvoo 8.8/10 Excellent (118) "Wonderful and the hostess was amazing!" CA $244 CA $276 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/Nauvoo-Hotels-Nauvoo-Grand-Bed-Breakfast.h8512062.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/40000000/39200000/39192200/39192154/64d77fff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, DVD player](https://images.trvl-media.com/lodging/40000000/39200000/39192200/39192154/c269f6aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, iron/ironing board, travel crib, free WiFi](https://images.trvl-media.com/lodging/40000000/39200000/39192200/39192154/5404cbe8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/40000000/39200000/39192200/39192154/385360d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Red Front Suite - Sleeps 15 Nauvoo 10/10 Exceptional (81) "Such a spacious stay! Plenty of room and awesome location. The restaurant below is delicious!" CA $91 CA $228 total includes taxes & fees Nov 1 - Nov 2 [](https://www.expedia.ca/Nauvoo-Hotels-The-Red-Front-Suite-Sleeps-15.h39192154.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/23000000/22870000/22869300/22869218/529310eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/23000000/22870000/22869300/22869218/68155d5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/23000000/22870000/22869300/22869218/323ba42b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/23000000/22870000/22869300/22869218/740564b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Relax on the River and Enjoy Southeast Iowa's Beauty Keosauqua 9.8/10 Exceptional (169) "We love this cabin. We've been several times now and love the river view and the relaxing environment " CA $161 CA $251 total includes taxes & fees Oct 15 - Oct 16 [](https://www.expedia.ca/Keosauqua-Hotels-Relax-On-The-River-And-Enjoy-Southeast-Iowas-Beauty.h22869218.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/84000000/83550000/83542100/83542038/dbc638da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/84000000/83550000/83542100/83542038/w506h639x260y44-f1ec642a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/84000000/83550000/83542100/83542038/79ee4c6e_edited_42c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, travel crib, free WiFi](https://images.trvl-media.com/lodging/84000000/83550000/83542100/83542038/4eee3559.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairy Bowery Nauvoo 8.2/10 Very good (53) "Such a quaint little stay! The property has so much character and charm! Great place to stay!" CA $100 CA $136 total includes taxes & fees Oct 16 - Oct 17 [](https://www.expedia.ca/Nauvoo-Hotels-Fairy-Bowery.h83542038.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/112000000/111040000/111035700/111035699/0c561263.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/112000000/111040000/111035700/111035699/f77e484a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111040000/111035700/111035699/aba0f90d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/112000000/111040000/111035700/111035699/9bb0b7d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nauvoo Windmill Farmhouse 10-12 people Niota 10/10 Exceptional (10) "We stayed for a week and enjkyed it. Comfortable home, on a nice quiet spot. Furniture and appliances were great and comfortable." CA $158 CA $294 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/Niota-Hotels-Nauvoo-Windmill-Farmhouse.h111035699.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/113000000/112110000/112101200/112101176/0beb6801.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/113000000/112110000/112101200/112101176/w2560h3373x0y40-2a6f02c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, DVD player](https://images.trvl-media.com/lodging/113000000/112110000/112101200/112101176/61737845.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/113000000/112110000/112101200/112101176/b0aa0631.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### A four bedroom hobbit hole style home five minutes from historic Nauvoo Illinois Nauvoo 10/10 Exceptional (8) "Loved the house it was so cute and fun. " CA $386 CA $494 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Nauvoo-Hotels-A-Four-Bedroom-Hobbit-Hole-Style-Home-Five-Minutes-From-Historic-Nauvoo-Illinois.h112101176.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/43000000/42650000/42641200/42641186/fb837b6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/43000000/42650000/42641200/42641186/58cc1522.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/43000000/42650000/42641200/42641186/30927266.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/43000000/42650000/42641200/42641186/f04272de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Experience Beautiful Pioneer Home In Nauvoo! Nauvoo 10/10 Exceptional (74) "We had a wonderful anniversary trip to Nauvoo. The historic and quaint Mix House added some period charm to our stay. While the house retains much of its 19th century charm, it has the modern conveniences needed for a relaxing stay. It may have been the off season, but food and meal choices were limited in Nauvoo itself. We were grateful for the items we ordered from The Apron Bake Shoppe." CA $267 CA $536 total includes taxes & fees Oct 16 - Oct 17 [](https://www.expedia.ca/Nauvoo-Hotels-Experience-Beautiful-Pioneer-Home-In-Nauvoo.h42641186.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/24000000/23620000/23612000/23611929/e15b71d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/24000000/23620000/23612000/23611929/bb3d2583.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/24000000/23620000/23612000/23611929/c8a07f7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/24000000/23620000/23612000/23611929/00124c26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Johnston Mansion Bed and Breakfast price shown is Vrbo Mansion price Keokuk 9.0/10 Wonderful (2) "Beautiful place in lovely, walkable neighborhood near the Mississippi. The hosts couldn't have been more accommodating or kind." CA $1,684 CA $2,619 total includes taxes & fees Oct 16 - Oct 17 [](https://www.expedia.ca/Keokuk-Hotels-Johnston-Mansion-Bed-And-Breakfast-Price-Shown-Is-Vrbo-Mansion-Price.h23611929.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-28&endDate=2025-10-29®ionId=6234151&adults=2&location_highlights_explore=winery&sort=RECOMMENDED&openPlayBack=true) ## Top Southeast Iowa Hotel Reviews ![Nauvoo Vacation Villas & Condos](//images.trvl-media.com/lodging/3000000/2230000/2227700/2227688/1951e7ed_y.jpg) ### Nauvoo Vacation Villas & Condos 10/10 Excellent "The set up was what we needed for our stay. The bed was comfortable and the AC worked properly. The kitchenette served our needs with a microwave, sink and refrigerator. The dead flies in the window sill were the only part of the room that was not up to par. " [](https://expedia.ca/Nauvoo-Hotels-Nauvoo-Vacation-Villas-Condos.h2227688.Hotel-Information) ![The Inn at Old Nauvoo](//images.trvl-media.com/lodging/4000000/3160000/3151900/3151830/w1899h1230x0y0-2f3f93ff_y.jpg) ### The Inn at Old Nauvoo 10/10 Excellent "Convenient location; comfortable room; friendly staff. " [](https://expedia.ca/Nauvoo-Hotels-Nauvoo-Family-Inn-And-Suites.h3151830.Hotel-Information) ![Quality Inn & Suites Fort Madison near Hwy 61](//images.trvl-media.com/lodging/1000000/970000/966600/966544/28d171d7_y.jpg) ### Quality Inn & Suites Fort Madison near Hwy 61 10/10 Excellent "Blood on the sheets " [](https://expedia.ca/Burlington-Hotels-Quality-Inn-Suites-Fort-Madison-Near-Hwy-61.h966544.Hotel-Information) ![Cobblestone Inn & Suites - Fort Madison](//images.trvl-media.com/lodging/10000000/9540000/9534800/9534717/ef5745b9_y.jpg) ### Cobblestone Inn & Suites - Fort Madison 10/10 Excellent "AC great. Breakfast super. Staff kind and most helpful. " [](https://expedia.ca/Burlington-Hotels-Cobblestone-Inn-Suites-Fort-Madison.h9534717.Hotel-Information) ![Super 8 by Wyndham Fort Madison](//images.trvl-media.com/lodging/1000000/60000/50200/50154/8a525277_y.jpg) ### Super 8 by Wyndham Fort Madison 10/10 Excellent "Cunfterbel" [](https://expedia.ca/Burlington-Hotels-Super-8-By-Wyndham-Fort-Madison.h50154.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [5 Star Hotels in Central United States](https://www.expedia.ca/5Star-Central-United-States-Hotels.s50-0-d6209877.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Quad Cities](https://www.expedia.ca/5Star-Quad-Cities-Hotels.s50-0-d603001.Travel-Guide-Filter-Hotels) - [Farmstay in Central United States](https://www.expedia.ca/Central-United-States-Agritourism.d6209877-aaAgritourism.Travel-Guide-Accommodation) - [B&B in Central United States](https://www.expedia.ca/Central-United-States-Bed-And-Breakfast.d6209877-aaBedAndBreakfast.Travel-Guide-Accommodation) - 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