Title: Book the Best BUSINESS Hotels in Southeastern Indiana in 2026 | Expedia.ca [Southeastern Indiana Travel Guide](https://expedia.ca/Southeastern-Indiana.dx6233889)[Hotels in Southeastern Indiana](https://expedia.ca/Southeastern-Indiana-Hotels.d6233889.Travel-Guide-Hotels)[Vacation Rentals in Southeastern Indiana](https://expedia.ca/Southeastern-Indiana-Vacation-Rentals.d6233889.Travel-Guide-VacationRentals)[Flights to Southeastern Indiana](https://expedia.ca/Cheap-Flights-To-Southeastern-Indiana.d6233889.Travel-Guide-Flights)[Southeastern Indiana Car Rentals](https://expedia.ca/Car-Rentals-In-Southeastern-Indiana.d6233889.Car-Rental-Guide)[Southeastern Indiana Vacation Packages](https://expedia.ca/Southeastern-Indiana.d6233889.Destination-Travel-Guides) ![Bathe in the forest...find this on the roof of the outdoor shower house down the hill from the guest house.](https://images.trvl-media.com/place/553248635989202622/88a60920-d501-4b4d-b386-caf78a7f4191.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Serendipity Trip # Find Business Hotels in Southeastern Indiana from CA $88 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southeastern Indiana Business Hotels Tonight [Dec 27 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6233889&startDate=2025-12-27&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 28 - Dec 29](https://www.expedia.ca/Hotel-Search?regionId=6233889&startDate=2025-12-28&endDate=2025-12-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=6233889&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) In two weeks [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6233889&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Southeastern Indiana business-friendly hotels ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/430000/426000/425912/b6106315.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/430000/426000/425912/d4a339a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 Queen Bed with Sofa bed, Non Smoking, Kitchen](https://images.trvl-media.com/lodging/1000000/430000/426000/425912/b9195057.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/426000/425912/62ca0639.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn by Wyndham Dry Ridge [](https://www.expedia.ca/Williamstown-Hotels-Microtel-Inn-By-Wyndham-Dry-Ridge.h425912.Hotel-Information) Dry Ridge 8.8/10 Excellent (1250) "Nice place our 3rd stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steve CA $80 CA $88 total includes taxes & fees Jan 3 - Jan 4, 2026 [](https://www.expedia.ca/Williamstown-Hotels-Microtel-Inn-By-Wyndham-Dry-Ridge.h425912.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356812/w3839h2492x0y0-b699260c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356812/4171bcac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356812/4e5f3e6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/32000000/31360000/31356900/31356812/a9510c79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Simpsonville [](https://www.expedia.ca/Louisville-Hotels-Hampton-Inn-Simpsonville.h31356812.Hotel-Information) Simpsonville 9.4/10 Exceptional (905) "Would stay again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chris CA $122 CA $136 total includes taxes & fees Jan 3 - Jan 4, 2026 [](https://www.expedia.ca/Louisville-Hotels-Hampton-Inn-Simpsonville.h31356812.Hotel-Information) ![Spa](https://images.trvl-media.com/lodging/4000000/3050000/3040400/3040377/771dbbc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/4000000/3050000/3040400/3040377/07e34b04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/4000000/3050000/3040400/3040377/d245cbfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3050000/3040400/3040377/8b5afb27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Richwood-Cincinnati South by IHG [](https://www.expedia.ca/Covington-Hotels-Holiday-Inn-Express-Hotel-Suites-Richwood-Cincinnati-South.h3040377.Hotel-Information) Walton 8.8/10 Excellent (1012) "Room was nice nice staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ricky CA $112 CA $126 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Covington-Hotels-Holiday-Inn-Express-Hotel-Suites-Richwood-Cincinnati-South.h3040377.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/480000/477700/477683/efd8b0ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/480000/477700/477683/7f7a5a06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/480000/477700/477683/d24df5c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/480000/477700/477683/7a243a71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Corydon by IHG [](https://www.expedia.ca/Corydon-Hotels-Holiday-Inn-Express-Corydon.h477683.Hotel-Information) Corydon 8.6/10 Excellent (362) "Very clean and great staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donna CA $119 CA $132 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Corydon-Hotels-Holiday-Inn-Express-Corydon.h477683.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/65000000/64420000/64410900/64410808/254e595c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/65000000/64420000/64410900/64410808/2ae0a12f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/65000000/64420000/64410900/64410808/4650cf22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/65000000/64420000/64410900/64410808/2eeb4b29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Clarksville - Louisville North [](https://www.expedia.ca/Louisville-Hotels-Best-Western-Plus-Louisville-North.h64410808.Hotel-Information) Clarksville 9.0/10 Wonderful (1001) "Great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ramakrishna CA $130 CA $147 total includes taxes & fees Jan 16 - Jan 17, 2026 [](https://www.expedia.ca/Louisville-Hotels-Best-Western-Plus-Louisville-North.h64410808.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/870000/869500/869431/18222049.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking (Wet Bar)](https://images.trvl-media.com/lodging/1000000/870000/869500/869431/79b63d6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/870000/869500/869431/e3cefcc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/870000/869500/869431/c0a7f8fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Madison near Clifty Falls [](https://www.expedia.ca/Madison-Hotels-Comfort-Inn.h869431.Hotel-Information) Madison 8.8/10 Excellent (666) "Great stay, clean, and comfy bed!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) cheryl CA $127 CA $146 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Madison-Hotels-Comfort-Inn.h869431.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/210000/203600/203577/93af407d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/210000/203600/203577/9567b3f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/203600/203577/30383672.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/210000/203600/203577/4fb063ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Corydon [](https://www.expedia.ca/Corydon-Hotels-Hampton-Inn-Corydon.h203577.Hotel-Information) Corydon 8.8/10 Excellent (602) "Courteous staff, clean room" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steven CA $145 CA $161 total includes taxes & fees Jan 3 - Jan 4, 2026 [](https://www.expedia.ca/Corydon-Hotels-Hampton-Inn-Corydon.h203577.Hotel-Information) ![Seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/90000/85100/85064/2cfb06f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/90000/85100/85064/5a41de65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/90000/85100/85064/e291ba56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/90000/85100/85064/f704f857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Louisville-North/Clarksville [](https://www.expedia.ca/Louisville-Hotels-Hampton-Inn-Louisville-NorthClarksville.h85064.Hotel-Information) Clarksville 8.8/10 Excellent (671) "Quiet location. Comfortable bed. Hot breakfast! Loved the strawberries, almonds, & whip cream for the waffles." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie CA $127 CA $143 total includes taxes & fees Jan 16 - Jan 17, 2026 [](https://www.expedia.ca/Louisville-Hotels-Hampton-Inn-Louisville-NorthClarksville.h85064.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/660000/659000/658960/dbc92ac1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/660000/659000/658960/12c46e60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/660000/659000/658960/545dc5db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/660000/659000/658960/dac1ba8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Sellersburg/Louisville North [](https://www.expedia.ca/Sellersburg-Hotels-Ramada-By-Wyndham-SellersburgLouisville-North.h658960.Hotel-Information) Sellersburg 8.4/10 Very good (1004) "Friendly service, clean rooms, comfortable beds, " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra CA $99 CA $112 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Sellersburg-Hotels-Ramada-By-Wyndham-SellersburgLouisville-North.h658960.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/120000/116900/116863/26236ff4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/120000/116900/116863/d433135c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/120000/116900/116863/8e60623f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/120000/116900/116863/e3881687.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Scottsburg by IHG [](https://www.expedia.ca/Madison-Hotels-Holiday-Inn-Express-Suites-Scottsburg.h116863.Hotel-Information) Scottsburg 8.8/10 Excellent (671) "Great staff and accommodations. Best holiday decorations of all the holiday inns!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary CA $194 CA $217 total includes taxes & fees Dec 30 - Dec 31 [](https://www.expedia.ca/Madison-Hotels-Holiday-Inn-Express-Suites-Scottsburg.h116863.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-10&endDate=2026-01-11®ionId=6233889&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Southeastern Indiana Hotel Reviews ![Hampton Inn New Albany Louisville West](https://images.trvl-media.com/lodging/1000000/30000/25400/25301/eb53eba8_y.jpg) ### Hampton Inn New Albany Louisville West 10/10 Excellent "yes, room was ok. staff good. the next mornings was a problem was the shower curtain. it was not tall enough to stop the water from flooding down to the toilet. this room 218 is a wheel chair room. I cleaned up the water as best I could. the shower curtain was not tall enough to touch the small roll over barirer for a wheelchair person. I reported tjis to the front desk. the stay is always good." [](https://expedia.ca/Louisville-Hotels-Hampton-Inn-New-Albany-Louisville-West.h25301.Hotel-Information) ![Radisson Hotel Louisville North](https://images.trvl-media.com/lodging/1000000/30000/26400/26306/50b82654_y.jpg) ### Radisson Hotel Louisville North 10/10 Excellent "Friendly staff. Great amenities. Easy access from Louisville via 2nd Street bridge. Nice clean rooms with plenty of pillows for maximum comfort. Even though I didn’t use the pool it is a nice size pool with plenty of room to just sit and relax. " [](https://expedia.ca/Louisville-Hotels-Radisson-Hotel-Louisville-North.h26306.Hotel-Information) ![Ramada by Wyndham Sellersburg/Louisville North](https://images.trvl-media.com/lodging/1000000/660000/659000/658960/dbc92ac1_y.jpg) ### Ramada by Wyndham Sellersburg/Louisville North 10/10 Excellent "Friendly service, clean rooms, comfortable beds, " [](https://expedia.ca/Sellersburg-Hotels-Ramada-By-Wyndham-SellersburgLouisville-North.h658960.Hotel-Information) ![Best Western Plus French Lick](https://images.trvl-media.com/lodging/11000000/10630000/10622000/10621919/814c5c73_y.jpg) ### Best Western Plus French Lick 10/10 Excellent "Breakfast was excellent and parking was easy. Comfortable room. " [](https://expedia.ca/French-Lick-Hotels-Best-Western-Plus-French-Lick.h10621919.Hotel-Information) ![Hampton Inn Louisville-North/Clarksville](https://images.trvl-media.com/lodging/1000000/90000/85100/85064/2cfb06f6_y.jpg) ### Hampton Inn Louisville-North/Clarksville 10/10 Excellent "Quiet location. Comfortable bed. Hot breakfast! Loved the strawberries, almonds, & whip cream for the waffles." [](https://expedia.ca/Louisville-Hotels-Hampton-Inn-Louisville-NorthClarksville.h85064.Hotel-Information) ![Best Western Green Tree Inn](https://images.trvl-media.com/lodging/1000000/30000/21100/21059/80ec0958_y.jpg) ### Best Western Green Tree Inn 10/10 Excellent "Yes " [](https://expedia.ca/Louisville-Hotels-Best-Western-Green-Tree-Inn.h21059.Hotel-Information) ![Sheraton Louisville Riverside by Marriott](https://images.trvl-media.com/lodging/1000000/20000/17900/17862/14fa367c_y.jpg) ### Sheraton Louisville Riverside by Marriott 10/10 Excellent "Staff was extremely friendly, helpful, and just exceptional all around. From check in to leaving the building we were greeted with kindness. Tim in club level was so kind and funny! I will definitely be staying here again, instead of the Galt House. " [](https://expedia.ca/Louisville-Hotels-Sheraton-Louisville-Riverside-Hotel.h17862.Hotel-Information) ![Big Splash Adventure Indoor Water Park & Resort](https://images.trvl-media.com/lodging/5000000/4860000/4857100/4857069/63744e7b_y.jpg) ### Big Splash Adventure Indoor Water Park & Resort 10/10 Excellent "Yes" [](https://expedia.ca/French-Lick-Hotels-Big-Splash-Adventure-Indoor-Water-Park-Resort.h4857069.Hotel-Information) ![Holiday Inn Express New Albany - Louisville NW by IHG](https://images.trvl-media.com/lodging/1000000/460000/456300/456275/a3ae5159_y.jpg) ### Holiday Inn Express New Albany - Louisville NW by IHG 10/10 Excellent "Staff was sweet! Beds are comfy, pillows suck but that’s ok." [](https://expedia.ca/Louisville-Hotels-Holiday-Inn-Express-New-Albany.h456275.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Southeastern Indiana cost? ### What are the best business-friendly hotels in Southeastern Indiana? ### How many business-friendly hotels are there in Southeastern Indiana? ### What are the best cheap business-friendly hotels in Southeastern Indiana? ### What are the top business-friendly motels in Southeastern Indiana? ### Are there any family-friendly hotels in Southeastern Indiana that are also business friendly? ### Are there any 5-star business-friendly hotels in Southeastern Indiana? ### Why book your business-friendly hotel in Southeastern Indiana with Expedia? ### How can I find cheap business-friendly hotels in Southeastern Indiana? ### What is there to do in Southeastern Indiana near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - 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