Southern Minnesota Vacation Rentals

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
Aug 15 - Aug 17
In two weeks
Aug 22 - Aug 24
In one month
Sep 5 - Sep 7
In two months
Oct 3 - Oct 5

Browse Select Southern Minnesota Vacation Homes

Riverside Retreat Near Town w Sauna, sleeps 8, Views & Abundant Activities!
Enjoy cooking in this well-equipped kitchen with appliances and ample countertop space.

Riverside Retreat Near Town w Sauna, sleeps 8, Views & Abundant Activities!

9.6 out of 10, Exceptional, (5)
Riverside Retreat Near Town w Sauna, sleeps 8, Views & Abundant Activities!
The Hen House Retreat - A Comfortable Place to Roost
Stroll through the charming garden, surrounded by lush plants and flowers, to the inviting porch with a comfortable bench.

The Hen House Retreat - A Comfortable Place to Roost

9.8 out of 10, Exceptional, (81)
"We enjoyed taking it easy watching some movies and crafting together for the weekend."
The price is CA $223
CA $273 total
includes taxes & fees
Aug 11 - Aug 12
The Hen House Retreat - A Comfortable Place to Roost
Lovely 2-bedroom LAKE house with AC in Fairmont
Compact kitchen with microwave, double sink, and wooden cabinetry, adjacent to a dining area with a wooden table and chairs.

Lovely 2-bedroom LAKE house with AC in Fairmont

9.0 out of 10, Wonderful, (2)
"Overall comfortable & adequate. Had some difficulty w/technology: key lock process (which Ashley helped with that). Couldn’t figure out access to TV “smart”. Also didn’t find hand towels until end of stay, but had plenty of wash cloths. Back door was “stuck”& hard to open. Main clock in TV room wall didn’t work (maybe just decorative), which kept confusing us when we looked up to see the time…& then just laughed because it was still 6:30! Liquid hand soap dispenser in upstairs bath was empty so...
Lovely 2-bedroom LAKE house with AC in Fairmont
Holiday Haus Zwei
Relax in this inviting living room with a sofa, armchairs, and a ceiling fan, offering a comfortable seating area with a view.

Holiday Haus Zwei

10.0 out of 10, Exceptional, (77)
"It was a great place to stay. Within walking distance of downtown."
The price is CA $557
CA $877 total
includes taxes & fees
Aug 22 - Aug 23
Holiday Haus Zwei
Mayo Discount! Main Floor bed, bath, and laundry. 3 blocks from Mayo Clinic
Enjoy meals in the kitchen with stainless steel appliances, a dining area, and a patio view.

Mayo Discount! Main Floor bed, bath, and laundry. 3 blocks from Mayo Clinic

10.0 out of 10, Exceptional, (32)
"This home is Central to the Mayo clinic The home is very nice and clean with everything you could possibly need for your stay. We would be back in a few months and definitely be staying here"
Mayo Discount! Main Floor bed, bath, and laundry. 3 blocks from Mayo Clinic
Log Inn on Madison Lake. Multi generation. Corporate retreat for team building
Cozy dining area with a large table and four chairs, surrounded by exposed beams and a large window offering a view of the surrounding landscape.

Log Inn on Madison Lake. Multi generation. Corporate retreat for team building

10.0 out of 10, Exceptional, (113)
"Everything we wanted expected and more"
Log Inn on Madison Lake. Multi generation. Corporate retreat for team building
Fantastic Large Home Right On Beautiful Lake Pepin!
Relax by the fire pit in a serene outdoor setting overlooking a tranquil body of water.

Fantastic Large Home Right On Beautiful Lake Pepin!

10.0 out of 10, Exceptional, (239)
"Great location, roomy house with all amenities needed. "
Fantastic Large Home Right On Beautiful Lake Pepin!
Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.
Enjoy cooking in this well-equipped kitchen with a double oven, microwave, and ample cabinetry.

Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.

10.0 out of 10, Exceptional, (90)
"perfect location perfect house. "
Charming 3 bed 1 bath home. 1 block to St. Mary's. 10 min walk to Mayo downtown.
Recliners. Single Level Living. Walk in shower.
Enjoy cooking in this well-equipped kitchen with a gas stove, refrigerator, and ample cabinetry.

Recliners. Single Level Living. Walk in shower.

10.0 out of 10, Exceptional, (21)
"Property is as described worked well for us."
Recliners. Single Level Living. Walk in shower.
Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!
Interior

Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!

9.4 out of 10, Exceptional, (12)
"We enjoyed our stay and appreciated how easy it was to reserve and communicate with the host! Thank you so much!"
The price is CA $138
CA $375 total
includes taxes & fees
Aug 17 - Aug 18
Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!
Victorian era Mississippi riverview retreat.
Residents enjoy scenic views of the water and surrounding hills from their homes.

Victorian era Mississippi riverview retreat.

9.8 out of 10, Exceptional, (29)
"Property was clean, comfortable, and just what we were looking for."
Victorian era Mississippi riverview retreat.
ARTISTS & ANGLERS INN - game room - home of Madison Lake Paddlefish!!
Escape to a serene lakeside haven with a grassy area, wooden bench, and tranquil stream.

ARTISTS & ANGLERS INN - game room - home of Madison Lake Paddlefish!!

9.8 out of 10, Exceptional, (73)
"We didn’t have much time to settle in, but were quite comfortable there."
ARTISTS & ANGLERS INN - game room - home of Madison Lake Paddlefish!!
The Cabin at Lowell
Relax in this cozy retreat with an outdoor space, comfortable seating area, and rustic charm.

The Cabin at Lowell

10.0 out of 10, Exceptional, (214)
"Wonderful property. Quiet, many activities available and so much to see. If you are looking to accommodate several friends or family members near the Mankato area, this is it! Owners very friendly and respectful of your privacy during the stay. "
The Cabin at Lowell
The Tritsch House -Beautifully Restored Queen Anne Alma WI - Central Air
Relax in a cozy space with a pool table, bookshelf, and potted plant.

The Tritsch House -Beautifully Restored Queen Anne Alma WI - Central Air

9.8 out of 10, Exceptional, (28)
"A perfect place to gather after a day of sight seeing. "
The Tritsch House -Beautifully Restored Queen Anne Alma WI - Central Air
AH #10 · AH #10 Full w/Shower
Stylish brick building with a flat roof and grid-patterned windows, set in an urban environment.

AH #10 · AH #10 Full w/Shower

9.4 out of 10, Exceptional, (13)
"We had a great and comfortable stay at this historic hotel. We were happily surprised about the bar in the basement, the friendly bartender and the delicious cocktails. The room was clean and comfortable and the breakfast buffet was tasty and fresh. "
The price is CA $164
CA $210 total
includes taxes & fees
Aug 11 - Aug 12
AH #10 · AH #10 Full w/Shower
Family friendly in the peaceful heart of town
Enjoy a peaceful retreat with a view of the surrounding neighborhood from the large window.

Family friendly in the peaceful heart of town

10.0 out of 10, Exceptional, (98)
"Stayed for a short weekend in Winona and was perfect. Great location and exactly as advertised."
Family friendly in the peaceful heart of town
Park in the Garage and Walk to Mayo Clinic
Relax in comfort with a bench and two armchairs, perfect for unwinding in a peaceful space.

Park in the Garage and Walk to Mayo Clinic

10.0 out of 10, Exceptional, (61)
"Cozy house that quick and easy to get to and from the hospital. Easy access to restaurants and all the main amenities that you need. "
Park in the Garage and Walk to Mayo Clinic
"Walden Pond" Adventure Amidst 44 Private Acres
Staircase leads to an upper level with rustic charm.

"Walden Pond" Adventure Amidst 44 Private Acres

10.0 out of 10, Exceptional, (132)
"Enjoyed our stay, good communication."
"Walden Pond" Adventure Amidst 44 Private Acres
Single Level Living with Comfortable Recliners
Enjoy meals in this kitchen with a sink, refrigerator, oven, and microwave, opening into a dining area with a view of the living room.

Single Level Living with Comfortable Recliners

10.0 out of 10, Exceptional, (33)
"It was really nice and clean"
Single Level Living with Comfortable Recliners
Harmony Home w/ Fire Pit: 5 Mi to Niagara Cave!
Compact kitchen with central island, sink, microwave, and stove, featuring light-colored cabinetry and a tiled backsplash.

Harmony Home w/ Fire Pit: 5 Mi to Niagara Cave!

9.6 out of 10, Exceptional, (8)
"House was very clean and full of amenities and instructions to make the stay easy and useful. Would stay here again in a heartbeat. "
Harmony Home w/ Fire Pit: 5 Mi to Niagara Cave!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Southern Minnesota Hotel Reviews

Country Inn & Suites Rochester South Mayo Clinic

Country Inn & Suites Rochester South Mayo Clinic

10/10 Excellent
"As desired. "
Diana 1-night trip
Posted 1 day ago
Country Inn & Suites Rochester South Mayo Clinic