Title: Book the Best Southern Minnesota SPA Resorts - Spa Hotels in Southern Minnesota, MN | Expedia.ca [Southern Minnesota Travel Guide](https://expedia.ca/Southern-Minnesota.dx6059950)[Hotels in Southern Minnesota](https://expedia.ca/Southern-Minnesota-Hotels.d6059950.Travel-Guide-Hotels)[Vacation Rentals in Southern Minnesota](https://expedia.ca/Southern-Minnesota-Vacation-Rentals.d6059950.Travel-Guide-VacationRentals)[Flights to Southern Minnesota](https://expedia.ca/Cheap-Flights-To-Southern-Minnesota.d6059950.Travel-Guide-Flights)[Southern Minnesota Car Rentals](https://expedia.ca/Car-Rentals-In-Southern-Minnesota.d6059950.Car-Rental-Guide)[Southern Minnesota Vacation Packages](https://expedia.ca/Southern-Minnesota.d6059950.Destination-Travel-Guides) ![Rochester showing a city and skyline](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63803-Rochester.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Southern Minnesota, MN - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southern Minnesota Spa Hotels Tonight [Nov 4 - Nov 5](https://www.expedia.ca/Hotel-Search?regionId=6059950&startDate=2025-11-04&endDate=2025-11-05&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 5 - Nov 6](https://www.expedia.ca/Hotel-Search?regionId=6059950&startDate=2025-11-05&endDate=2025-11-06&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6059950&startDate=2025-11-07&endDate=2025-11-09&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=6059950&startDate=2025-11-14&endDate=2025-11-16&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Southern Minnesota Spa Hotels ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/10000/8900/8820/a6d4835a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/10000/8900/8820/8e8e2669.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Library](https://images.trvl-media.com/lodging/1000000/10000/8900/8820/1e966b86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite Riverside](https://images.trvl-media.com/lodging/1000000/10000/8900/8820/caabe547.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### St James Hotel, a Historic Hotel of America Red Wing 9.2/10 Wonderful (1027) "Great hotel. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tina CA $190 CA $218 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/Red-Wing-Hotels-St-James-Hotel.h8820.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/b1555778.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/f4c0d6e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/86063f91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, Multiple Beds | Living area](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/c7a0b093.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Rochester Mayo Clinic Area Downtown Rochester 9.6/10 Exceptional (526) "Best stay in downtown Rochester in years. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anita CA $241 CA $277 total includes taxes & fees Dec 5 - Dec 6 [](https://www.expedia.ca/Rochester-Hotels-Hilton-Rochester-Mayo-Clinic-Area.h27426319.Hotel-Information) ![Luxury Single Room](https://images.trvl-media.com/lodging/47000000/46990000/46980900/46980893/e51df0cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/47000000/46990000/46980900/46980893/02fc8ee1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Single Room](https://images.trvl-media.com/lodging/47000000/46990000/46980900/46980893/a183938d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/47000000/46990000/46980900/46980893/455654ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Round Barn Farm B & B Event Center Red Wing 10/10 Exceptional (39) "Beautiful property with great hosts! Strongly recommend!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Austin [](https://www.expedia.ca/Red-Wing-Hotels-Round-Barn-Farm-B-B-Event-Center.h46980893.Hotel-Information) ![Serves lunch, dinner, and happy hour](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/3bd995bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/3b0f1e42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, desk](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/8d7f7147.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Rochester Near Mayo Clinic Rochester 8.2/10 Very good (1092) "Great staffing, excellent rooms, very good continental breakfast with scrambled eggs, sausage, toast, bagels, waffles, yogurt and more. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul CA $110 CA $126 total includes taxes & fees Nov 30 - Dec 1 [](https://www.expedia.ca/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/16000000/15300000/15291300/15291258/f590e78a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/16000000/15300000/15291300/15291258/516cac96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/16000000/15300000/15291300/15291258/20c6a208.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/16000000/15300000/15291300/15291258/9d21a7b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grandstay Hotel and Suites Waseca 7.6/10 Good (243) "Friendly check in and speedy check out." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas CA $120 CA $133 total includes taxes & fees Nov 10 - Nov 11 [](https://www.expedia.ca/Owatonna-Hotels-Grandstay-Hotel-And-Suites.h15291258.Hotel-Information) ![Couples treatment rooms, sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/63000000/62980000/62975100/62975084/dde8f410.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Buffet](https://images.trvl-media.com/lodging/63000000/62980000/62975100/62975084/e29bfb18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Buffet](https://images.trvl-media.com/lodging/63000000/62980000/62975100/62975084/8ef4784f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/63000000/62980000/62975100/62975084/d7f6084e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Falls Casino & Golf Resort Larchwood 8.6/10 Excellent (198) "We had a great stay at Grand Falls Casino. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aaron [](https://www.expedia.ca/Larchwood-Hotels-Grand-Falls-Casino-Golf-Resort.h62975084.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/200000/199000/198946/d6da8b6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/200000/199000/198946/0fb5698e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/200000/199000/198946/61e51f32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/199000/198946/673d14c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mystic Lake Casino Hotel Prior Lake 9.0/10 Wonderful (2300) "Great hotel and restaurants. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donna CA $172 CA $192 total includes taxes & fees Dec 4 - Dec 5 [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-Mystic-Lake-Casino-Hotel.h198946.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392992/046c19a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392992/78c8d9c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Non Smoking](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392992/c5b36452.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392992/b08684c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Brookings Brookings 9.2/10 Wonderful (607) "Very clean, great breakfast, nice pool area" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Katelyn CA $149 CA $165 total includes taxes & fees Nov 18 - Nov 19 [](https://www.expedia.ca/De-Smet-Hotels-Hampton-Inn-Suites-Brookings.h2392992.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/7000000/6010000/6006100/6006027/4d619c92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/7000000/6010000/6006100/6006027/21e5520d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/7000000/6010000/6006100/6006027/ed52d40e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/7000000/6010000/6006100/6006027/94cbd2df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Minneapolis SW - Shakopee by IHG Shakopee 9.4/10 Exceptional (872) "Cleanliness, staff was very friendly, breakfast, all around great place!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William CA $122 CA $136 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-Holiday-Inn-Express-Hotel-Suites-Minneapolis-SW-Shakopee.h6006027.Hotel-Information) ![Couples treatment rooms, sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/55000000/54180000/54172300/54172209/93adc461.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/55000000/54180000/54172300/54172209/b65aee43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dinner served](https://images.trvl-media.com/lodging/55000000/54180000/54172300/54172209/06ffc248.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/55000000/54180000/54172300/54172209/91361409.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omni Viking Lakes Hotel Eagan 9.6/10 Exceptional (931) "Hotel was clean well kept and the staff was very helpful" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Parker CA $190 CA $211 total includes taxes & fees Nov 24 - Nov 25 [](https://www.expedia.ca/Minneapolis-St-Paul-Hotels-Omni-Viking-Lakes-Hotel.h54172209.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-19&endDate=2025-11-20®ionId=6059950&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Southern Minnesota Hotel Reviews ![Spark by Hilton Rochester South](//images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/w3837h2557x3y3-c2ce9db3_y.jpg) ### Spark by Hilton Rochester South 10/10 Excellent "Quick, easy check-in. Room was clean. Bed was very comfortable." [](https://expedia.ca/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![Kahler Grand Hotel](//images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg) ### Kahler Grand Hotel 10/10 Excellent "Perfect staff to greet you and answer all your inquiries." [](https://expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![Med City Inn & Suites - Mayo Clinic Area](//images.trvl-media.com/lodging/1000000/10000/4200/4106/4b21fb74_y.jpg) ### Med City Inn & Suites - Mayo Clinic Area 10/10 Excellent "Nice room, friendly staff." [](https://expedia.ca/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) ![Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area](//images.trvl-media.com/lodging/1000000/10000/3600/3556/b33056f7_y.jpg) ### Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area 10/10 Excellent "The staff was excellent. We were there for a hockey tournament and the lobby was packed with people trying to check in. Staff was courteous and helpful in handling the crowd. " [](https://expedia.ca/Rochester-Hotels-Centerstone-Plaza-Hotel-Soldiers-FieldMayo-Clinic-Area.h3556.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S](//images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353_y.jpg) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S 10/10 Excellent "Breakfast-N/A Parking-✅" [](https://expedia.ca/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![Kahler Inn and Suites - Mayo Clinic Area](//images.trvl-media.com/lodging/1000000/180000/171600/171566/e56e7dae_y.jpg) ### Kahler Inn and Suites - Mayo Clinic Area 10/10 Excellent "Access to the Mayo clinic was superior." [](https://expedia.ca/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) ![AmericInn by Wyndham Rochester Near Mayo Clinic](//images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30_y.jpg) ### AmericInn by Wyndham Rochester Near Mayo Clinic 10/10 Excellent "Super friendly and helpful staff. " [](https://expedia.ca/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![Country Inn & Suites Rochester South Mayo Clinic](//images.trvl-media.com/lodging/1000000/460000/455600/455558/c3584a83_y.jpg) ### Country Inn & Suites Rochester South Mayo Clinic 10/10 Excellent "Clean room. Good heating system. A little hard to find though. 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