Title: Book the Best BUSINESS Hotels in Southern Minnesota in 2026 | Expedia.ca [Southern Minnesota Travel Guide](https://expedia.ca/Southern-Minnesota.dx6059950)[Hotels in Southern Minnesota](https://expedia.ca/Southern-Minnesota-Hotels.d6059950.Travel-Guide-Hotels)[Vacation Rentals in Southern Minnesota](https://expedia.ca/Southern-Minnesota-Vacation-Rentals.d6059950.Travel-Guide-VacationRentals)[Flights to Southern Minnesota](https://expedia.ca/Cheap-Flights-To-Southern-Minnesota.d6059950.Travel-Guide-Flights)[Southern Minnesota Car Rentals](https://expedia.ca/Car-Rentals-In-Southern-Minnesota.d6059950.Car-Rental-Guide)[Southern Minnesota Vacation Packages](https://expedia.ca/Southern-Minnesota.d6059950.Destination-Travel-Guides) ![Lake Pepin & Mississippi River Scenic View](https://images.trvl-media.com/place/553248621532649642/b0facbcd-16cb-4461-946e-105f314f35fc.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Southern Minnesota, MN from CA $117 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southern Minnesota Business Hotels Tonight [Dec 14 - Dec 15](https://www.expedia.ca/Hotel-Search?regionId=6059950&startDate=2025-12-14&endDate=2025-12-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 15 - Dec 16](https://www.expedia.ca/Hotel-Search?regionId=6059950&startDate=2025-12-15&endDate=2025-12-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6059950&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) In two weeks [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6059950&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Southern Minnesota business-friendly hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/330000/327900/327855/1573f723.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/330000/327900/327855/ada372fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/330000/327900/327855/a2f21d02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/330000/327900/327855/2dd8d149.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Worthington by IHG [](https://www.expedia.ca/Worthington-Hotels-Holiday-Inn-Express-Suites-Worthington.h327855.Hotel-Information) Worthington 9.0/10 Wonderful (307) "Room was very clean. Staff who checked me in were both cheerful and easy/fun to talk to." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephanie CA $157 CA $174 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Worthington-Hotels-Holiday-Inn-Express-Suites-Worthington.h327855.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/540000/538500/538443/7134cbc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/540000/538500/538443/b75bfa05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/540000/538500/538443/b174610c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/540000/538500/538443/fbd34e02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Albert Lea - Austin [](https://www.expedia.ca/Owatonna-Hotels-Country-Inn-Suites-By-Radisson.h538443.Hotel-Information) Albert Lea 9.0/10 Wonderful (1001) "Nice place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary CA $109 CA $121 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Owatonna-Hotels-Country-Inn-Suites-By-Radisson.h538443.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1250000/1245300/1245223/036a88bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1250000/1245300/1245223/80a0577c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1250000/1245300/1245223/0ef4d851.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/2000000/1250000/1245300/1245223/c9303a3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Jackson [](https://www.expedia.ca/Worthington-Hotels-AmericInn-By-Wyndham-Jackson.h1245223.Hotel-Information) Jackson 8.4/10 Very good (431) "Clean, breakfast at Pennys excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Randel CA $142 CA $157 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Worthington-Hotels-AmericInn-By-Wyndham-Jackson.h1245223.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/2300/2270/03b116ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/2300/2270/6351153f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 King Bed (Lanai) | Minibar](https://images.trvl-media.com/lodging/1000000/10000/2300/2270/33aa3792.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 King Bed](https://images.trvl-media.com/lodging/1000000/10000/2300/2270/047b14ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Austin, MN [](https://www.expedia.ca/Rochester-Hotels-Holiday-Inn-Austin.h2270.Hotel-Information) Austin 8.2/10 Very good (551) "Very nice hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Douglas CA $123 CA $136 total includes taxes & fees Dec 16 - Dec 17 [](https://www.expedia.ca/Rochester-Hotels-Holiday-Inn-Austin.h2270.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/8000000/7340000/7332200/7332128/03a3b0c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/8000000/7340000/7332200/7332128/50cfb9bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free full breakfast](https://images.trvl-media.com/lodging/8000000/7340000/7332200/7332128/78f67452.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/8000000/7340000/7332200/7332128/b87a239e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites Marshall - University Area [](https://www.expedia.ca/Marshall-Hotels-Sleep-Inn-Suites-Marshall.h7332128.Hotel-Information) Marshall 9.0/10 Wonderful (454) "Nice place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $139 CA $156 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Marshall-Hotels-Sleep-Inn-Suites-Marshall.h7332128.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/40000000/40000000/39999300/39999228/9694b265.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/40000000/40000000/39999300/39999228/7abeade2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/40000000/40000000/39999300/39999228/3c209054.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/40000000/40000000/39999300/39999228/35ffad98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cobblestone Hotel & Suites - Austin [](https://www.expedia.ca/Rochester-Hotels-Cobblestone-Hotel-Suites-Austin.h39999228.Hotel-Information) Austin 9.0/10 Wonderful (664) "place was great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) joel CA $105 CA $117 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Rochester-Hotels-Cobblestone-Hotel-Suites-Austin.h39999228.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/bd0b7bbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/290eee76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/f4426c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Indigo Rochester – Mayo Clinic Area by IHG [](https://www.expedia.ca/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) Downtown Rochester 8.8/10 Excellent (887) "Great room and stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Trevor CA $105 CA $121 total includes taxes & fees Dec 26 - Dec 27 [](https://www.expedia.ca/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) ![Suite, Accessible](https://images.trvl-media.com/lodging/6000000/6000000/5992000/5991960/0b6238a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/6000000/6000000/5992000/5991960/bc20b74a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/6000000/6000000/5992000/5991960/960e4078.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/6000000/6000000/5992000/5991960/705a332b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites and Conference Center [](https://www.expedia.ca/Worthington-Hotels-Comfort-Suites-And-Conference-Center.h5991960.Hotel-Information) Worthington 9.0/10 Wonderful (465) "It was a nice place for a family of 5 with a free breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Holly CA $182 CA $202 total includes taxes & fees Dec 16 - Dec 17 [](https://www.expedia.ca/Worthington-Hotels-Comfort-Suites-And-Conference-Center.h5991960.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/6000000/5640000/5637500/5637459/21e50121.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed, Accessible](https://images.trvl-media.com/lodging/6000000/5640000/5637500/5637459/1a8fcd83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Jetted Tub | Bathroom](https://images.trvl-media.com/lodging/6000000/5640000/5637500/5637459/2c62df05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/6000000/5640000/5637500/5637459/bdf22633.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grandstay Hotel And Suites Luverne [](https://www.expedia.ca/Worthington-Hotels-Grandstay-Hotel-And-Suites-Luverne.h5637459.Hotel-Information) Luverne 9.2/10 Wonderful (739) "Beds were super comfy! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kurt [](https://www.expedia.ca/Worthington-Hotels-Grandstay-Hotel-And-Suites-Luverne.h5637459.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/117000000/116830000/116821600/116821505/bf664ca8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/117000000/116830000/116821600/116821505/02a168e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/117000000/116830000/116821600/116821505/w8153h5434x0y0-91ebdd70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/117000000/116830000/116821600/116821505/d3bdf62b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Mankato [](https://www.expedia.ca/Mankato-Hotels-Towneplace-Suites-By-Marriott-Mankato.h116821505.Hotel-Information) Mankato 9.8/10 Exceptional (21) "Excellent stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tabitha Maria CA $145 CA $161 total includes taxes & fees Dec 27 - Dec 28 [](https://www.expedia.ca/Mankato-Hotels-Towneplace-Suites-By-Marriott-Mankato.h116821505.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-28&endDate=2025-12-29®ionId=6059950&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Southern Minnesota Hotel Reviews ![Hampton Inn Rochester-South](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/f90bd051_y.jpg) ### Hampton Inn Rochester-South 10/10 Excellent "I stayed at this hotel for three days during my Christmas shopping in Rochester. It is a very clean hotel. While my room was rather on the small side, it really wasn't an issue being it was just myself. The pool and whirlpool area is awesome, and there was a variety of breakfast items for the three mornings I ate there. This hotel also offered free soup every evening from 6 -- 7\. I didn't have the opportunity to take advantage of this, but thought it was a great complimentary item." [](https://expedia.ca/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information) ![Aspen Suites](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/6c7e0658_y.jpg) ### Aspen Suites 10/10 Excellent "Everything was impeccable. The staff incredible. Amenities incredible. Colton at the desk was extremely professional and courteous to all of the guests. So impressive and he knew all of the guests by there names and remembered what their needs were. Colton is an employee anyone would want at the helm. Also he was so professional serving soup to guests. This hotel hit all of the marks that anyone would look for during their travel. Thank you all so much. Amazing. Chef JSW" [](https://expedia.ca/Rochester-Hotels-Aspen-Suites.h904615.Hotel-Information) ![SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys](https://images.trvl-media.com/lodging/1000000/110000/102000/101902/39da8a7c_y.jpg) ### SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys 10/10 Excellent "Room was warm, appreciate disinfectant wipes for remotes! Great staff!" [](https://expedia.ca/Rochester-Hotels-SpringHill-Suites-By-Marriott-Rochester-Mayo-ClinicSt-Marys.h101902.Hotel-Information) ![Spark by Hilton Rochester South](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/w3837h2557x3y3-c2ce9db3_y.jpg) ### Spark by Hilton Rochester South 10/10 Excellent "Hotels was very clean and staff was very friendly. " [](https://expedia.ca/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353_y.jpg) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S 10/10 Excellent "I have stayed here a couple times in the past. The renovations are spot on. The cleanliness was superb. The staff were very friendly. The roll in shower and hearing impaired room worked out great for my health issues. It was an easy check in online. " [](https://expedia.ca/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![Kahler Inn and Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/e56e7dae_y.jpg) ### Kahler Inn and Suites - Mayo Clinic Area 10/10 Excellent "Staff is alway very polite" [](https://expedia.ca/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) ![Kahler Grand Hotel](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg) ### Kahler Grand Hotel 10/10 Excellent "Staff was friendly and helpful! Will continue to stay here while at the Mayo, " [](https://expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![AmericInn by Wyndham Rochester Near Mayo Clinic](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30_y.jpg) ### AmericInn by Wyndham Rochester Near Mayo Clinic 10/10 Excellent "Clean room and great staff" [](https://expedia.ca/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![St James Hotel, a Historic Hotel of America](https://images.trvl-media.com/lodging/1000000/10000/8900/8820/c90b9231_y.jpg) ### St James Hotel, a Historic Hotel of America 10/10 Excellent "Lovely room, great restaurant on site, free parking, nice staff." [](https://expedia.ca/Red-Wing-Hotels-St-James-Hotel.h8820.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Southern Minnesota cost? ### What are the best business-friendly hotels in Southern Minnesota? ### How many business-friendly hotels are there in Southern Minnesota? ### What are the best cheap business-friendly hotels in Southern Minnesota? ### What are the top business-friendly motels in Southern Minnesota? ### Are there any family-friendly hotels in Southern Minnesota that are also business friendly? ### Are there any 5-star business-friendly hotels in Southern Minnesota? ### Why book your business-friendly hotel in Southern Minnesota with Expedia? ### How can I find cheap business-friendly hotels in Southern Minnesota? ### What is there to do in Southern Minnesota near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [5 Star Hotels in Springfield ](https://www.expedia.ca/5Star-Springfield-Hotels.s50-0-d6046558.Travel-Guide-Filter-Hotels) - 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