Find luxury hotels in South San Diego, CA

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on South San Diego Luxury Hotels

Tonight
Aug 28 - Aug 29
Tomorrow
Aug 29 - Aug 30
This weekend
Aug 29 - Aug 31
Next weekend
Sep 5 - Sep 7

Top South San Diego Luxury Hotels

The Rambler Motel
View from room

The Rambler Motel

3.0 star property
9.0 out of 10, Wonderful, (1906)
"Great stay"
The price is CA $150
CA $174 total
includes taxes & fees
Sep 17 - Sep 18
The Rambler Motel
Hercor Hotel - Urban Boutique
Deluxe Room, 1 King Bed

Hercor Hotel - Urban Boutique

3.0 star property
8.6 out of 10, Excellent, (1235)
"Great place to stay!"
The price is CA $144
CA $159 total
includes taxes & fees
Sep 1 - Sep 2
Hercor Hotel - Urban Boutique
Howard Johnson Suites by Wyndham San Diego Chula Vista/BayFt
Studio Suite, 1 King Bed with Sofa bed, Accessible, Non Smoking (Mobility Accessible)

Howard Johnson Suites by Wyndham San Diego Chula Vista/BayFt

2.0 star property
6.6 out of 10, (1003)
"Cool place to stay"
The price is CA $163
CA $179 total
includes taxes & fees
Sep 7 - Sep 8
Howard Johnson Suites by Wyndham San Diego Chula Vista/BayFt
Hotel Palmeras Chula Vista
Front of property

Hotel Palmeras Chula Vista

2.0 star property
7.0 out of 10, Good, (1849)
"Great stay"
The price is CA $116
CA $128 total
includes taxes & fees
Aug 31 - Sep 1
Hotel Palmeras Chula Vista
El Primero Hotel
Miscellaneous

El Primero Hotel

2.5 star property
9.2 out of 10, Wonderful, (1001)
"Favorite Hotel in Chula Vista"
The price is CA $135
CA $149 total
includes taxes & fees
Aug 31 - Sep 1
El Primero Hotel
La Quinta Inn by Wyndham San Diego Chula Vista
Exterior

La Quinta Inn by Wyndham San Diego Chula Vista

3.0 star property
8.6 out of 10, Excellent, (1385)
"Great place to stay at , along with a good breakfast variety. Overall I'll stay here again"
The price is CA $143
CA $157 total
includes taxes & fees
Sep 7 - Sep 8
La Quinta Inn by Wyndham San Diego Chula Vista
Best Western Americana Inn
1 bedroom, pillowtop beds, in-room safe, desk

Best Western Americana Inn

2.5 star property
9.0 out of 10, Wonderful, (1141)
"Breakfast was amazing! "
The price is CA $169
CA $192 total
includes taxes & fees
Sep 4 - Sep 5
Best Western Americana Inn
Comfort Inn Chula Vista San Diego South
Lobby

Comfort Inn Chula Vista San Diego South

2.5 star property
8.0 out of 10, Very good, (1051)
"Good place to stay when in the area."
The price is CA $147
CA $162 total
includes taxes & fees
Sep 7 - Sep 8
Comfort Inn Chula Vista San Diego South
Quality Suites San Diego Otay Mesa
Desk, laptop workspace, blackout drapes, iron/ironing board

Quality Suites San Diego Otay Mesa

2.5 star property
7.2 out of 10, Good, (1006)
"Nice place. Clean and quiet. "
The price is CA $148
CA $169 total
includes taxes & fees
Sep 21 - Sep 22
Quality Suites San Diego Otay Mesa
Big 7 Motel Chula Vista I-5
Reception

Big 7 Motel Chula Vista I-5

2.5 star property
6.2 out of 10, (931)
"The hotel is suitable for a one-night stay or a short visit. The staff is friendly, and the place was clean, which is the most important thing."
The price is CA $93
CA $115 total
includes taxes & fees
Aug 31 - Sep 1
Big 7 Motel Chula Vista I-5
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about South San Diego

Find out more about South San Diego

Popular luxurious hotels

Most upscale stays in South San Diego in 2025

Luxury hotels in South San Diego
5-Star hotels
5-Star hotels
4-Star hotels
4-Star hotels

Top South San Diego Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia