Title: Best South San Diego Apart hotels | Expedia.ca [South San Diego Travel Guide](https://expedia.ca/South-San-Diego.dx553248632063518562)[Hotels in South San Diego](https://expedia.ca/South-San-Diego-Hotels.d553248632063518562.Travel-Guide-Hotels)[Vacation Rentals in South San Diego](https://expedia.ca/South-San-Diego-Vacation-Rentals.d553248632063518562.Travel-Guide-VacationRentals)[Flights to South San Diego](https://expedia.ca/Cheap-Flights-To-South-San-Diego.d553248632063518562.Travel-Guide-Flights)[Things to do in South San Diego](https://expedia.ca/Things-To-Do-In-South-San-Diego.d553248632063518562.Travel-Guide-Activities)[South San Diego Car Rentals](https://expedia.ca/Car-Rentals-In-South-San-Diego.d553248632063518562.Car-Rental-Guide)[South San Diego Vacation Packages](https://expedia.ca/South-San-Diego.d553248632063518562.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/1577a5f9f9b33dbc18377fc367dd66b8.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Apart Hotels in South San Diego ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248632063518562&startDate=2025-10-24&endDate=2025-10-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248632063518562&startDate=2025-10-31&endDate=2025-11-02&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=553248632063518562&startDate=2025-11-14&endDate=2025-11-16&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=553248632063518562&startDate=2025-12-12&endDate=2025-12-14&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select South San Diego Aparthotels ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/b82a5191.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/dd5fc603.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/w2000h1293x0y90-00acac65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/d0f0db5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sentral Gaslamp Quarter Downtown San Diego 9.2/10 Wonderful (477) "Great place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary CA $198 CA $271 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/San-Diego-Hotels-Sentral-Gaslamp-Quarter.h114116366.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/79e8f033.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe 2 King Bedrooms, Multiple Beds, Sleeps 11ppl | Terrace/patio](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/6ef835b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/1b9a69bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/6c7bbd52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City24 Hotel Little Italy Mission Hills Middletown 9.6/10 Exceptional (92) "Great place to stay with my family of 9!!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erica CA $178 CA $248 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/San-Diego-Hotels-City24-Hotel-Little-Italy-Mission-Hill.h104140458.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/f051791c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/4195877c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/87b3eb35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/84cf0a12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Uptown Inn by Vantaggio - Limited Service Apart-Hotel Hillcrest 8.2/10 Very good (242) "Convenient in a great walkable area of town. Staff was great from check-in to check-out" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $135 CA $152 total includes taxes & fees Nov 19 - Nov 20 [](https://www.expedia.ca/San-Diego-Hotels-Uptown-Inn.h104283827.Hotel-Information) ![Queen Bed Studio with Patio | Terrace/patio](https://images.trvl-media.com/lodging/115000000/114920000/114912200/114912134/d0adc246.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/115000000/114920000/114912200/114912134/6c3d2bf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shared kitchen facilities](https://images.trvl-media.com/lodging/115000000/114920000/114912200/114912134/cab2e937.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/115000000/114920000/114912200/114912134/34f7fb43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Little Italy Inn - Limited Service Apart Hotel Downtown San Diego 8.0/10 Very good (82) "Loved my stay there! I will definitely be back :)" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ramya alexis CA $147 CA $167 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/San-Diego-Hotels-Little-Italy-Inn.h114912134.Hotel-Information) ![Deluxe Studio, 1 Queen Bed (Self Check-in with Virtual Front Desk)](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/0f983451.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![40-inch flat-screen TV with digital channels, TV, streaming services](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/52541661.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Suite, 1 Queen Bed (Self Check-in with Virtual Front Desk) | Private kitchen](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/fbd31f74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mini-fridge, microwave, stovetop, electric kettle](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/10234b1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kasa Gaslamp Quarter San Diego Downtown San Diego 8.0/10 Very good (140) "Plenty of restaurants all in walking distance. Given the area of the room could be quieter but other than that it was a very nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melisa CA $132 CA $151 total includes taxes & fees Oct 21 - Oct 22 [](https://www.expedia.ca/San-Diego-Hotels-Sonder-The-Marin.h15681965.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/aa0ca94d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 2 Bedrooms, Bay View (QueenBed) | Balcony view](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/f6cadddf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Apartment, 2 Bedrooms](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/ad340e76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/9ea3f4ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kasa Little Italy San Diego Downtown San Diego 9.6/10 Exceptional (331) "The amenities are world-class!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alexander CA $214 CA $367 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/San-Diego-Hotels-Kasa-Little-Italy-San-Diego.h108772597.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-02&endDate=2025-11-03®ionId=553248632063518562&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSouth-San-Diego-Apart-Hotels.d553248632063518562-aaApartHotels.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSouth-San-Diego-Apart-Hotels.d553248632063518562-aaApartHotels.Travel-Guide-Accommodation) ## Top South San Diego Hotel Reviews ![Courtyard by Marriott San Diego Downtown Little Italy](//images.trvl-media.com/lodging/1000000/20000/13300/13205/0339a25b_y.jpg) ### Courtyard by Marriott San Diego Downtown Little Italy 10/10 Excellent "Me encantó la vista .!! " [](https://expedia.ca/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) ![InterContinental San Diego by IHG](//images.trvl-media.com/lodging/27000000/26990000/26984300/26984236/8b765f45_y.jpg) ### InterContinental San Diego by IHG 10/10 Excellent "I loved how there was a starbucks and so many walkable restaurants in the area. I will say parking was very limited since we do have a tall truck but the staff was super understanding and flexible. Absolutely would return. " [](https://expedia.ca/San-Diego-Hotels-InterContinental-San-Diego.h26984236.Hotel-Information) ![Handlery Hotel](//images.trvl-media.com/lodging/1000000/10000/8400/8374/ab6ccd55_y.jpg) ### Handlery Hotel 10/10 Excellent "Clean " [](https://expedia.ca/San-Diego-Hotels-Handlery-Hotel.h8374.Hotel-Information) ![Legacy Resort Hotel & Spa](//images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/0bbd67f4_y.jpg) ### Legacy Resort Hotel & Spa 10/10 Excellent "Clean, safe, great room, plenty of parking, and friendly staff" [](https://expedia.ca/San-Diego-Hotels-Legacy-Resort-Hotel-Spa.h41504735.Hotel-Information) ![Hotel del Coronado, Curio Collection by Hilton](//images.trvl-media.com/lodging/1000000/10000/7500/7496/20fe4d95_y.jpg) ### Hotel del Coronado, Curio Collection by Hilton 10/10 Excellent "We had a secluded poolside room with cabana. It was very pleasant to lay out scantily dressed on the sofa and having a nice cup of coffee first thing in the morning! It's a beautiful hotel rich with history. My boyfriend checked this off his bucket list and we had the best vacation together in beautiful San Diego! " [](https://expedia.ca/Coronado-Hotels-Hotel-Del-Coronado.h7496.Hotel-Information) ![The Dana on Mission Bay](//images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg) ### The Dana on Mission Bay 10/10 Excellent "Pool area was great " [](https://expedia.ca/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![Comfort Inn San Diego Airport At The Harbor](//images.trvl-media.com/lodging/1000000/10000/8800/8727/17ffc972_y.jpg) ### Comfort Inn San Diego Airport At The Harbor 10/10 Excellent "I’ve not had breakfast yet,, checked in at 2, it’s now 8:55 pm" [](https://expedia.ca/San-Diego-Hotels-Comfort-Inn-San-Diego-Airport-At-The-Harbor.h8727.Hotel-Information) ![Hilton San Diego Mission Valley](//images.trvl-media.com/lodging/1000000/20000/16100/16019/w3839h2160x1y0-98566ca3_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "Staff at time of check in were great, clean room. " [](https://expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ![Wyndham Garden San Diego Near SeaWorld](//images.trvl-media.com/lodging/1000000/50000/41000/40962/76b78879_y.jpg) ### Wyndham Garden San Diego Near SeaWorld 10/10 Excellent "Staff at front desk was very professional and friendly. Room had plenty of space for our family. " [](https://expedia.ca/San-Diego-Hotels-Wyndham-Garden-San-Diego-Near-SeaWorld.h40962.Hotel-Information) ## Find out more about South San Diego ## South San Diego Aparthotels information | Number of reviews | | | --- | --- | | Accommodation | Aparthotels | | Lowest Price | | | Highest Price | | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [Hotels near Beyer Blvd Trolley Station](https://www.expedia.ca/Beyer-Blvd-Trolley-Station-Hotels.d6186828.Travel-Guide-Hotels) - [Camino Real Hotels in Castle Park](https://www.expedia.ca/Castle-Park-Chula-Vista-Hotels-Camino-Real.0-n177686-0--bCaminoReal.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in Castle Park](https://www.expedia.ca/Castle-Park-Chula-Vista-Hotels-Couples-Resorts-Hotels.0-n177686-0-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Apartments in Chula Vista](https://www.expedia.ca/Chula-Vista-Apartments.d7442-aaApartments.Travel-Guide-Accommodation) - 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[Otay Hotels](https://www.expedia.ca/Otay-Chula-Vista-Hotels.0-n177685-0.Travel-Guide-Filter-Hotels) - [Adults Only Resorts & in Otay Mesa West](https://www.expedia.ca/Otay-Mesa-West-San-Diego-Hotels-Adults-Only-Resorts.0-n553248625809641010-0-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Otay Mesa West](https://www.expedia.ca/Otay-Mesa-West-San-Diego-Hotels-Cheap-Hotels.0-n553248625809641010-0-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels with Balconies in Otay Mesa West](https://www.expedia.ca/Otay-Mesa-West-San-Diego-Hotels-Hotels-With-Balconies.0-n553248625809641010-0-tHotelswithBalconies.Travel-Guide-Filter-Hotels) - [Otay Mesa West Hotels](https://www.expedia.ca/Otay-Mesa-West-San-Diego-Hotels.0-n553248625809641010-0.Travel-Guide-Filter-Hotels) - [Lgbt Friendly Hotels in Otay Ranch Village West](https://www.expedia.ca/Otay-Ranch-Village-West-Chula-Vista-Hotels-LGBT-Friendly-Hotel.0-n553248635976473051-0-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - [Otay Ranch Village West Hotels](https://www.expedia.ca/Otay-Ranch-Village-West-Chula-Vista-Hotels.0-n553248635976473051-0.Travel-Guide-Filter-Hotels) - 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