Title: Book the Best Southern Indiana SPA Resorts from CA $125 - Spa Hotels in Southern Indiana | Expedia.ca

[Southern Indiana Travel Guide](https://expedia.ca/Southern-Indiana.dx6059635)[Hotels in Southern Indiana](https://expedia.ca/Southern-Indiana-Hotels.d6059635.Travel-Guide-Hotels)[Vacation Rentals in Southern Indiana](https://expedia.ca/Southern-Indiana-Vacation-Rentals.d6059635.Travel-Guide-VacationRentals)[Flights to Southern Indiana](https://expedia.ca/Cheap-Flights-To-Southern-Indiana.d6059635.Travel-Guide-Flights)[Southern Indiana Car Rentals](https://expedia.ca/Car-Rentals-In-Southern-Indiana.d6059635.Car-Rental-Guide)[Southern Indiana Vacation Packages](https://expedia.ca/Southern-Indiana.d6059635.Destination-Travel-Guides)

![Belle of Louisville which includes a bay or harbour and a ferry as well as a small group of people](https://images.trvl-media.com/place/6062661/de2e6e20-7fec-4f19-8f1c-b6f175615380.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/6062661/de2e6e20-7fec-4f19-8f1c-b6f175615380.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check availability on Southern Indiana Spa Hotels

Tonight

[Jan 20 - Jan 21](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2026-01-20&endDate=2026-01-21&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Jan 21 - Jan 22](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2026-01-21&endDate=2026-01-22&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2026-01-23&endDate=2026-01-25&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2026-01-30&endDate=2026-02-01&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Southern Indiana hotels with a spa

![3 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/54f0e03a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/80fbdedc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/506c167d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Casino](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/bea44cd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Caesars Southern Indiana - A Caesars Rewards Destination

[](https://www.expedia.ca/Elizabeth-Hotels-Caesars-Southern-Indiana.h795844.Hotel-Information)

Elizabeth

8.2/10

Very good

(1,005 reviews)

"Rooms were spacious and clean. Bathroom spacious and clean. Liked the proximity to the casino"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jaime

[](https://www.expedia.ca/Elizabeth-Hotels-Caesars-Southern-Indiana.h795844.Hotel-Information)

![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/e725185b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/23521baa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 2 Bedrooms, Non Smoking (East Twr, Waterview, 2 Queens, 1 King)](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/38ee770d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/9c82234b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Galt House Hotel Trademark Collection by Wyndham

[](https://www.expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information)

Downtown Louisville

9.0/10

Wonderful

(4,008 reviews)

"Great hotel"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lazaro

CA $186

CA $219 total

includes taxes & fees

Jan 27 - Jan 28

[](https://www.expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1160000/1152900/1152807/04047b8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/2000000/1160000/1152900/1152807/30bbd7c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Golf](https://images.trvl-media.com/lodging/2000000/1160000/1152900/1152807/7f00b921.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool, open 9:00 AM to 9:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/2000000/1160000/1152900/1152807/162eb275.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Belterra Casino Resort

[](https://www.expedia.ca/Madison-Hotels-Belterra-Casino-Resort.h1152807.Hotel-Information)

Florence

8.6/10

Excellent

(1,001 reviews)

" The hotel staff was excellent friendly and rooms was excellent clean,comfortable,Quite definitely a place we recommend to others."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ronald

CA $235

CA $280 total

includes taxes & fees

Jan 25 - Jan 26

[](https://www.expedia.ca/Madison-Hotels-Belterra-Casino-Resort.h1152807.Hotel-Information)

![Room (Asleep in the Cyclone)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/fdd94051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room (Asleep in the Cyclone)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/aaadeb96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/22b7d23e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fountain](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/864ff441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 21c Museum Hotel Louisville

[](https://www.expedia.ca/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information)

Downtown Louisville

9.4/10

Exceptional

(1,000 reviews)

"Location and the staff was fabulous."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Madeline

CA $195

CA $236 total

includes taxes & fees

Jan 25 - Jan 26

[](https://www.expedia.ca/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information)

![Sauna, body treatments, aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/4c7c479b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/9798709f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bars/lounges, cocktail bar, lobby lounge](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/547de83e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 6:30 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/e2fb9d56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Omni Louisville Hotel

[](https://www.expedia.ca/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information)

Downtown Louisville

9.2/10

Wonderful

(1,764 reviews)

"Beautiful, spacious hotel. Spotless room, kind and helpful staff."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gizella

CA $232

CA $273 total

includes taxes & fees

Jan 21 - Jan 22

[](https://www.expedia.ca/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information)

![32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/00e4c915.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/eec2d0c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/071da00d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/2ec829de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Reserve on Main

[](https://www.expedia.ca/Louisville-Hotels-The-Reserve-On-Main.h121877336.Hotel-Information)

Downtown Louisville

10/10

Exceptional

(1 review)

"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

georgios

CA $229

CA $335 total

includes taxes & fees

Jan 21 - Jan 22

[](https://www.expedia.ca/Louisville-Hotels-The-Reserve-On-Main.h121877336.Hotel-Information)

![Exterior detail](https://images.trvl-media.com/lodging/107000000/106920000/106915400/106915308/95d9177a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Staircase](https://images.trvl-media.com/lodging/107000000/106920000/106915400/106915308/1e2d6baa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/107000000/106920000/106915400/106915308/787112cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/107000000/106920000/106915400/106915308/94b6bd82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Central Park Bed & Breakfast

[](https://www.expedia.ca/Louisville-Hotels-Central-Park-Bed-Breakfast.h106915308.Hotel-Information)

Old Louisville

9.2/10

Wonderful

(59 reviews)

"Our stay here was excellent in every way! The owners were very sweet and went out of their way to assist us in every way, the rooms were very cozy, and the breakfasts were fantastic. This is the best B&B we've ever stayed."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

John

CA $177

CA $206 total

includes taxes & fees

Jan 25 - Jan 26

[](https://www.expedia.ca/Louisville-Hotels-Central-Park-Bed-Breakfast.h106915308.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/49600/49545/a62748ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/49600/49545/1ea5b0fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Iron/ironing board, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/50000/49600/49545/914ff829.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free continental breakfast](https://images.trvl-media.com/lodging/1000000/50000/49600/49545/d25d1009.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn Seymour I-65

[](https://www.expedia.ca/Columbus-Hotels-Quality-Inn-Seymour-I-65.h49545.Hotel-Information)

Seymour

7.0/10

Good

(566 reviews)

"Was quiet and enjoyed our stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

BARBARA

CA $112

CA $125 total

includes taxes & fees

Feb 18 - Feb 19

[](https://www.expedia.ca/Columbus-Hotels-Quality-Inn-Seymour-I-65.h49545.Hotel-Information)

![Bar (on property)](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/40c412dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/82066f84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Apartment, Multiple Beds, Pets Allowed, Garden View | Living area](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/3fd39b2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Signature Apartment, 1 King Bed with Sofa bed, Pets Allowed, Garden View | Terrace/patio](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/46f16aa2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pillow and Paddock B&B

[](https://www.expedia.ca/Louisville-Hotels-Pillow-And-Paddock-BB.h11688222.Hotel-Information)

La Grange

10/10

Exceptional

(52 reviews)

"Courteous staff and the room was outstanding. It was our second stay at the inn. Everything is first class. We highly recommend it."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Fran

CA $475

CA $524 total

includes taxes & fees

Feb 16 - Feb 17

[](https://www.expedia.ca/Louisville-Hotels-Pillow-And-Paddock-BB.h11688222.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-03&endDate=2026-02-04&regionId=6059635&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true)

## Top Southern Indiana Hotel Reviews

![Drury Inn & Suites Evansville East](https://images.trvl-media.com/lodging/1000000/120000/116600/116545/2ba5f829_y.jpg)

### Drury Inn & Suites Evansville East

10/10 Excellent

"Everything is perfect. "

[](https://expedia.ca/Evansville-Hotels-Drury-Inn-Suites-Evansville-East.h116545.Hotel-Information)

![Hampton Inn New Albany Louisville West](https://images.trvl-media.com/lodging/1000000/30000/25400/25301/eb53eba8_y.jpg)

### Hampton Inn New Albany Louisville West

10/10 Excellent

"nice staff and warm, comfy lobby. "

[](https://expedia.ca/Louisville-Hotels-Hampton-Inn-New-Albany-Louisville-West.h25301.Hotel-Information)

![Ramada by Wyndham Sellersburg/Louisville North](https://images.trvl-media.com/lodging/1000000/660000/659000/658960/dbc92ac1_y.jpg)

### Ramada by Wyndham Sellersburg/Louisville North

10/10 Excellent

"The hotel was very nice and the staff was pleasant and helpful"

[](https://expedia.ca/Sellersburg-Hotels-Ramada-By-Wyndham-SellersburgLouisville-North.h658960.Hotel-Information)

![Big Splash Adventure Indoor Water Park & Resort](https://images.trvl-media.com/lodging/5000000/4860000/4857100/4857069/63744e7b_y.jpg)

### Big Splash Adventure Indoor Water Park & Resort

10/10 Excellent

"Yes"

[](https://expedia.ca/French-Lick-Hotels-Big-Splash-Adventure-Indoor-Water-Park-Resort.h4857069.Hotel-Information)

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