Title: Book the Best Southern Indiana LUXURY Hotels - Upscale Hotels in Southern Indiana | Expedia.ca

[Southern Indiana Travel Guide](https://expedia.ca/Southern-Indiana.dx6059635)[Hotels in Southern Indiana](https://expedia.ca/Southern-Indiana-Hotels.d6059635.Travel-Guide-Hotels)[Vacation Rentals in Southern Indiana](https://expedia.ca/Southern-Indiana-Vacation-Rentals.d6059635.Travel-Guide-VacationRentals)[Flights to Southern Indiana](https://expedia.ca/Cheap-Flights-To-Southern-Indiana.d6059635.Travel-Guide-Flights)[Southern Indiana Car Rentals](https://expedia.ca/Car-Rentals-In-Southern-Indiana.d6059635.Car-Rental-Guide)[Southern Indiana Vacation Packages](https://expedia.ca/Southern-Indiana.d6059635.Destination-Travel-Guides)

![Belle of Louisville which includes a bay or harbour and a ferry as well as a small group of people](https://images.trvl-media.com/place/6062661/de2e6e20-7fec-4f19-8f1c-b6f175615380.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/6062661/de2e6e20-7fec-4f19-8f1c-b6f175615380.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check availability on Southern Indiana Luxury Hotels

Tonight

[Feb 4 - Feb 5](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2026-02-04&endDate=2026-02-05&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Tomorrow

[Feb 5 - Feb 6](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2026-02-05&endDate=2026-02-06&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

This weekend

[Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2026-02-06&endDate=2026-02-08&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Next weekend

[Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2026-02-13&endDate=2026-02-15&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

## Our top choices for Southern Indiana luxury hotels

![Room (Asleep in the Cyclone)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/fdd94051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fountain](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/864ff441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/06213b95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room (Asleep in the Cyclone)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/aaadeb96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 21c Museum Hotel Louisville

[](https://www.expedia.ca/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information)

Downtown Louisville

9.4/10

Exceptional

(1,000 reviews)

"Location and the staff was fabulous."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Madeline

CA $244

CA $294 total

includes taxes & fees

Feb 5 - Feb 6

[](https://www.expedia.ca/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1750000/1745100/1745075/220feee7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Aerial view](https://images.trvl-media.com/lodging/2000000/1750000/1745100/1745075/9d2787c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1750000/1745100/1745075/2586f244.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Serves lunch and dinner](https://images.trvl-media.com/lodging/2000000/1750000/1745100/1745075/97ea6860.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### West Baden Springs Hotel

[](https://www.expedia.ca/West-Baden-Springs-Hotels-West-Baden-Springs-Hotel.h1745075.Hotel-Information)

West Baden Springs

9.6/10

Exceptional

(310 reviews)

"The hotel West Baden is awesome they have 24 hour trolley that runs every 15 minutes and will take you anywhere in the area."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anonymous traveller

[](https://www.expedia.ca/West-Baden-Springs-Hotels-West-Baden-Springs-Hotel.h1745075.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/764d3439.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/2a2a7fb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/3c2671ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/4fd8456f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Brown Hotel

[](https://www.expedia.ca/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information)

Downtown Louisville

9.4/10

Exceptional

(1,179 reviews)

"Fantastic place to stay in Louisville."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nathaniel

[](https://www.expedia.ca/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information)

![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/aa5bcd07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/9d86b349.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/0261f02d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/63654a82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Galt House Hotel Trademark Collection by Wyndham

[](https://www.expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information)

Downtown Louisville

9.0/10

Wonderful

(4,038 reviews)

"Great hotel"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lazaro

CA $211

CA $248 total

includes taxes & fees

Feb 17 - Feb 18

[](https://www.expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/5bea9d61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed, Non Smoking, Corner | Living area](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/07f1fa14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/f30004bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/edc62f96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Embassy Suites Louisville Downtown

[](https://www.expedia.ca/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information)

Downtown Louisville

9.0/10

Wonderful

(1,149 reviews)

"Great room and breakfast. Close to several nice restaurants."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Crystal

CA $167

CA $196 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information)

![Desk, blackout drapes, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/27100/27037/a454a7ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/27100/27037/0b818ec5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/27100/27037/806851a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/27100/27037/abad6281.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Econo Lodge Louisville Downtown

[](https://www.expedia.ca/Louisville-Hotels-Econo-Lodge-Downtown-Louisville.h27037.Hotel-Information)

Downtown Louisville

7.2/10

Good

(1,001 reviews)

"Staff courtesy, clean room, breakfast was good."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Dave

CA $86

CA $101 total

includes taxes & fees

Feb 17 - Feb 18

[](https://www.expedia.ca/Louisville-Hotels-Econo-Lodge-Downtown-Louisville.h27037.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/d22f4bf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/w3839h2557x0y0-ff0d1f72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/52012810.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hilton, Deluxe Suite, 1 Queen Bed, Non Smoking | Living area](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/83bc3758.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Seelbach Hilton Louisville Downtown

[](https://www.expedia.ca/Louisville-Hotels-The-Seelbach-Hilton-Louisville.h25958.Hotel-Information)

Downtown Louisville

8.6/10

Excellent

(1,001 reviews)

"The area was congested but the motel was good. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Byrd

CA $202

CA $238 total

includes taxes & fees

Feb 7 - Feb 8

[](https://www.expedia.ca/Louisville-Hotels-The-Seelbach-Hilton-Louisville.h25958.Hotel-Information)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/70000/67700/67603/23cddac1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/70000/67700/67603/7de8c10f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/70000/67700/67603/a69d7825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/70000/67700/67603/w391h300x0y0-9ca648dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Baymont by Wyndham Corydon

[](https://www.expedia.ca/Corydon-Hotels-Baymont-By-Wyndham-Corydon.h67603.Hotel-Information)

Corydon

7.6/10

Good

(1,002 reviews)

"Room was very clean very nice front desk"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Roger

CA $93

CA $103 total

includes taxes & fees

Feb 22 - Feb 23

[](https://www.expedia.ca/Corydon-Hotels-Baymont-By-Wyndham-Corydon.h67603.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/6000000/5810000/5801000/5800938/5fef5386.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/6000000/5810000/5801000/5800938/873f48bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/6000000/5810000/5801000/5800938/0e84f1cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down comforters, pillowtop beds, desk](https://images.trvl-media.com/lodging/6000000/5810000/5801000/5800938/3040b0bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Courtyard by Marriott Evansville East

[](https://www.expedia.ca/Evansville-Hotels-Courtyard-By-Marriott-Evansville-East.h5800938.Hotel-Information)

Evansville

8.8/10

Excellent

(1,001 reviews)

"Clean and comfortable! Loved everything about it."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Maureen

CA $190

CA $218 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/Evansville-Hotels-Courtyard-By-Marriott-Evansville-East.h5800938.Hotel-Information)

![Individually furnished, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/21200/21199/b9a48afc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Individually furnished, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/21200/21199/ea45f657.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21200/21199/6e350e03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Individually furnished, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/21200/21199/34c11704.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Travelodge by Wyndham Sellersburg / Louisville North

[](https://www.expedia.ca/Sellersburg-Hotels-Travelodge-By-Wyndham-Sellersburg-Louisville-North.h21199.Hotel-Information)

Sellersburg

6.6/10

(702 reviews)

"Bed was decent"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Melissa

CA $92

CA $104 total

includes taxes & fees

Feb 11 - Feb 12

[](https://www.expedia.ca/Sellersburg-Hotels-Travelodge-By-Wyndham-Sellersburg-Louisville-North.h21199.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-18&endDate=2026-02-19&regionId=6059635&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true)

## Top Southern Indiana Hotel Reviews

![Sheraton Louisville Riverside by Marriott](https://images.trvl-media.com/lodging/1000000/20000/17900/17862/14fa367c_y.jpg)

### Sheraton Louisville Riverside by Marriott

10/10 Excellent

"Friendly helpful staff, clean rooms, well equipped gym. Easy parking & walkable to restaurants & town. Louisville just over the bridge."

[](https://expedia.ca/Louisville-Hotels-Sheraton-Louisville-Riverside-Hotel.h17862.Hotel-Information)

![Hampton Inn New Albany Louisville West](https://images.trvl-media.com/lodging/1000000/30000/25400/25301/eb53eba8_y.jpg)

### Hampton Inn New Albany Louisville West

10/10 Excellent

"nice staff and warm, comfy lobby. "

[](https://expedia.ca/Louisville-Hotels-Hampton-Inn-New-Albany-Louisville-West.h25301.Hotel-Information)

![One Life Studios ](https://images.trvl-media.com/lodging/1000000/20000/12200/12148/c306d08d_y.jpg)

### One Life Studios 

10/10 Excellent

"Loved our time so much thank you."

[](https://expedia.ca/Evansville-Hotels-One-Life-Studios.h12148.Hotel-Information)

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