Title: Book the Best Southern Indiana LUXURY Hotels - Upscale Hotels in Southern Indiana | Expedia.ca

 

[Southern Indiana Travel Guide](https://expedia.ca/Southern-Indiana.dx6059635)[Hotels in Southern Indiana](https://expedia.ca/Southern-Indiana-Hotels.d6059635.Travel-Guide-Hotels)[Vacation Rentals in Southern Indiana](https://expedia.ca/Southern-Indiana-Vacation-Rentals.d6059635.Travel-Guide-VacationRentals)[Flights to Southern Indiana](https://expedia.ca/Cheap-Flights-To-Southern-Indiana.d6059635.Travel-Guide-Flights)[Southern Indiana Car Rentals](https://expedia.ca/Car-Rentals-In-Southern-Indiana.d6059635.Car-Rental-Guide)[Southern Indiana Vacation Packages](https://expedia.ca/Southern-Indiana.d6059635.Destination-Travel-Guides)

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# Find luxury hotels in Southern Indiana

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## Check availability on Southern Indiana Luxury Hotels

Tonight

[Oct 31 - Nov 1](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2025-10-31&endDate=2025-11-01&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Tomorrow

[Nov 1 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2025-11-01&endDate=2025-11-02&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

This weekend

[Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2025-10-31&endDate=2025-11-02&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Next weekend

[Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2025-11-07&endDate=2025-11-09&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

## Top Southern Indiana Luxury Hotels

![Front of property](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/a9b7038a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fountain](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/864ff441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room (Asleep in the Cyclone)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/fdd94051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/cef338e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 21c Museum Hotel Louisville

Downtown Louisville

9.2/10

Wonderful

(1001)

"Room was very clean and staff were very friendly. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jennifer

CA $225

CA $272 total

includes taxes & fees

Nov 20 - Nov 21

[](https://www.expedia.ca/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1750000/1745100/1745075/220feee7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Serves lunch and dinner](https://images.trvl-media.com/lodging/2000000/1750000/1745100/1745075/97ea6860.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1750000/1745100/1745075/bff88489.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/2000000/1750000/1745100/1745075/14a6fe74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### West Baden Springs Hotel

West Baden Springs

9.6/10

Exceptional

(310)

"The hotel West Baden is awesome they have 24 hour trolley that runs every 15 minutes and will take you anywhere in the area."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anonymous traveller

[](https://www.expedia.ca/West-Baden-Springs-Hotels-West-Baden-Springs-Hotel.h1745075.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/840e31de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/f0221042.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/4fd8456f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/3c2671ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Brown Hotel

Downtown Louisville

9.4/10

Exceptional

(1125)

"Wonderful hotel with lots of history; clean rooms; Nice lounge and restaurants."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kim

CA $213

CA $250 total

includes taxes & fees

Nov 1 - Nov 2

[](https://www.expedia.ca/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information)

![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/b5c46c3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/ab0af7cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/23521baa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/594caae3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Galt House Hotel Trademark Collection by Wyndham

Downtown Louisville

9.0/10

Wonderful

(3707)

"Great place to stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tia

CA $186

CA $219 total

includes taxes & fees

Nov 25 - Nov 26

[](https://www.expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information)

![Dinner served](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/e02820b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/5bea9d61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/c4d1fb67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/f30004bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Embassy Suites Louisville Downtown

Downtown Louisville

9.0/10

Wonderful

(1051)

"Clean hotel, amazing breakfast, staff is very friendly and area is accessible!"

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Maggy

CA $171

CA $201 total

includes taxes & fees

Nov 9 - Nov 10

[](https://www.expedia.ca/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information)

![Standard Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/27100/27037/1942d798.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/27100/27037/bea3ec0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/27100/27037/c90e9ace.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/27100/27037/0b818ec5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Econo Lodge Louisville Downtown

Downtown Louisville

7.2/10

Good

(1002)

"Overall very good motel, walking distance to bars Room we’re very good. Lots of parking but $8 per night fee. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Judy

CA $88

CA $103 total

includes taxes & fees

Nov 17 - Nov 18

[](https://www.expedia.ca/Louisville-Hotels-Econo-Lodge-Downtown-Louisville.h27037.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/3d017cc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/e898c223.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/aa5a75a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full breakfast for a fee](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/52012810.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Seelbach Hilton Louisville Downtown

Downtown Louisville

8.6/10

Excellent

(1001)

"This was a lovely stay and we will definitely return. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Dolorse

CA $192

CA $226 total

includes taxes & fees

Nov 27 - Nov 28

[](https://www.expedia.ca/Louisville-Hotels-The-Seelbach-Hilton-Louisville.h25958.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/1000000/70000/67700/67603/48eca275.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/70000/67700/67603/d973f209.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/70000/67700/67603/w391h300x0y0-9ca648dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/70000/67700/67603/a69d7825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Baymont by Wyndham Corydon

Corydon

7.6/10

Good

(1010)

"Great place quite. and staff was excellent at the desk "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Larry

CA $93

CA $103 total

includes taxes & fees

Dec 1 - Dec 2

[](https://www.expedia.ca/Corydon-Hotels-Baymont-By-Wyndham-Corydon.h67603.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/6000000/5810000/5801000/5800938/5fef5386.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/6000000/5810000/5801000/5800938/0e84f1cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down comforters, pillowtop beds, desk](https://images.trvl-media.com/lodging/6000000/5810000/5801000/5800938/3040b0bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/6000000/5810000/5801000/5800938/21794f5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Courtyard by Marriott Evansville East

Evansville

8.8/10

Excellent

(1001)

"It was a great stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jeffery

CA $194

CA $224 total

includes taxes & fees

Nov 2 - Nov 3

[](https://www.expedia.ca/Evansville-Hotels-Courtyard-By-Marriott-Evansville-East.h5800938.Hotel-Information)

![Individually furnished, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/21200/21199/ae9fc284.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21200/21199/9ed272c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Individually furnished, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/21200/21199/9df99d11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21200/21199/9d7ffb91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Travelodge by Wyndham Sellersburg / Louisville North

Sellersburg

6.6/10

(697)

"Breakfast fast was decent."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

DeWayne

CA $94

CA $106 total

includes taxes & fees

Nov 11 - Nov 12

[](https://www.expedia.ca/Sellersburg-Hotels-Travelodge-By-Wyndham-Sellersburg-Louisville-North.h21199.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-14&endDate=2025-11-15&regionId=6059635&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true)

## Top Southern Indiana Hotel Reviews

![Comfort Inn & Suites Evansville Airport](//images.trvl-media.com/lodging/1000000/50000/40500/40405/4020e7b5_y.jpg)

### Comfort Inn & Suites Evansville Airport

10/10 Excellent

"Hotel was easily accessible and right off interstate. Staff was friendly and kept it clean. The bed was comfortable. "

[](https://expedia.ca/Evansville-Hotels-Comfort-Inn-Suites-Evansville-Airport.h40405.Hotel-Information)

![Sheraton Louisville Riverside by Marriott](//images.trvl-media.com/lodging/1000000/20000/17900/17862/14fa367c_y.jpg)

### Sheraton Louisville Riverside by Marriott

10/10 Excellent

"Good"

[](https://expedia.ca/Louisville-Hotels-Sheraton-Louisville-Riverside-Hotel.h17862.Hotel-Information)

![Hampton Inn New Albany Louisville West](//images.trvl-media.com/lodging/1000000/30000/25400/25301/eb53eba8_y.jpg)

### Hampton Inn New Albany Louisville West

10/10 Excellent

"Very comfortable beds, good parking, pleasant staff, clean rooms, shower was good. My husband, his mother and i enjyes our stay"

[](https://expedia.ca/Louisville-Hotels-Hampton-Inn-New-Albany-Louisville-West.h25301.Hotel-Information)

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-   [Red Roof Inn Hotels in Southwestern Indiana](https://www.expedia.ca/Southwestern-Indiana-Hotels-Red-Roof-Inn.0-0-d6233876--bRedRoofInn.Travel-Guide-Filter-Hotels)
-   [Southwestern Indiana Hotels](https://www.expedia.ca/Southwestern-Indiana-Hotels.d6233876.Travel-Guide-Hotels)
-   [Resorts in Southwestern Indiana](https://www.expedia.ca/Southwestern-Indiana-Resort-Hotels.d6233876-aaResortHotels.Travel-Guide-Accommodation)

-   [Flights to Ohio River Valley](https://www.expedia.ca/Cheap-Flights-To-Ohio-River-Valley.d6233674.Travel-Guide-Flights)
-   [Flights to Southwestern Indiana](https://www.expedia.ca/Cheap-Flights-To-Southwestern-Indiana.d6233876.Travel-Guide-Flights)
-   [Flights from Calgary to Ohio River Valley](https://www.expedia.ca/lp/flights/178245/6233674/calgary-to-ohio-river-valley)
-   [Flights from Dallas to Ohio River Valley](https://www.expedia.ca/lp/flights/178253/6233674/dallas-to-ohio-river-valley)
-   [Flights from Miami to Ohio River Valley](https://www.expedia.ca/lp/flights/178286/6233674/miami-to-ohio-river-valley)
-   [Flights from Minneapolis - St. Paul to Ohio River Valley](https://www.expedia.ca/lp/flights/178287/6233674/minneapolis-st-paul-to-ohio-river-valley)
-   [Flights from Orlando to Ohio River Valley](https://www.expedia.ca/lp/flights/178294/6233674/orlando-to-ohio-river-valley)
-   [Flights from Toronto to Ohio River Valley](https://www.expedia.ca/lp/flights/178314/6233674/toronto-to-ohio-river-valley)
-   [Flights from Vancouver to Ohio River Valley](https://www.expedia.ca/lp/flights/178315/6233674/vancouver-to-ohio-river-valley)
-   [Flights from Edmonton to Ohio River Valley](https://www.expedia.ca/lp/flights/180002/6233674/edmonton-to-ohio-river-valley)
-   [Flights from Québec City to Ohio River Valley](https://www.expedia.ca/lp/flights/180017/6233674/quebec-city-to-ohio-river-valley)
-   [Flights from Fort Lauderdale to Ohio River Valley](https://www.expedia.ca/lp/flights/601750/6233674/fort-lauderdale-to-ohio-river-valley)
-   [Flights from Newark to Ohio River Valley](https://www.expedia.ca/lp/flights/601760/6233674/newark-to-ohio-river-valley)
-   [Flights from Buffalo to Ohio River Valley](https://www.expedia.ca/lp/flights/602674/6233674/buffalo-to-ohio-river-valley)
-   [Flights from Birmingham to Ohio River Valley](https://www.expedia.ca/lp/flights/602981/6233674/birmingham-to-ohio-river-valley)
-   [Flights from Ohio River Valley](https://www.expedia.ca/lp/flights/6233674/flights-from-ohio-river-valley)

-   [Kentucky Lake](https://www.expedia.ca/Kentucky-Lake-United-States-of-America.d6059618.Vacation-Attraction)
-   [Visit Ohio River Valley](https://www.expedia.ca/Ohio-River-Valley.dx6233674)
-   [Visit Southwestern Indiana](https://www.expedia.ca/Southwestern-Indiana.dx6233876)

-   [Advantage Rent-A-Car Rental Cars in Ohio River Valley](https://www.expedia.ca/Advantage-Rent-A-Car-Car-Rentals-In-Ohio-River-Valley.d6233674-c3.Car-Rental-Guide-Suppliers)
-   [Pickup Car Rentals in Ohio River Valley](https://www.expedia.ca/Pickup-Car-Rentals-In-Ohio-River-Valley.d6233674-tPickup.Car-Rental-Guide-Class)
-   [Thrifty Car Rental Rental Cars in Ohio River Valley](https://www.expedia.ca/Thrifty-Car-Rental-Car-Rentals-In-Ohio-River-Valley.d6233674-c45.Car-Rental-Guide-Suppliers)

-   [Book Luxury Hotels in Southern Indiana on Expedia.com](https://www.expedia.com/Southern-Indiana-Hotels-Luxury-Hotel.0-0-d6059635-tLuxuryHotel.Travel-Guide-Filter-Hotels)