Title: Book the Best Southern Indiana LUXURY Hotels - Upscale Hotels in Southern Indiana | Expedia.ca

[Southern Indiana Travel Guide](https://expedia.ca/Southern-Indiana.dx6059635)[Hotels in Southern Indiana](https://expedia.ca/Southern-Indiana-Hotels.d6059635.Travel-Guide-Hotels)[Vacation Rentals in Southern Indiana](https://expedia.ca/Southern-Indiana-Vacation-Rentals.d6059635.Travel-Guide-VacationRentals)[Flights to Southern Indiana](https://expedia.ca/Cheap-Flights-To-Southern-Indiana.d6059635.Travel-Guide-Flights)[Southern Indiana Car Rentals](https://expedia.ca/Car-Rentals-In-Southern-Indiana.d6059635.Car-Rental-Guide)[Southern Indiana Vacation Packages](https://expedia.ca/Southern-Indiana.d6059635.Destination-Travel-Guides)

![Belle of Louisville which includes a bay or harbour and a ferry as well as a small group of people](https://images.trvl-media.com/place/6062661/de2e6e20-7fec-4f19-8f1c-b6f175615380.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Find luxury hotels in Southern Indiana

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## Check availability on Southern Indiana Luxury Hotels

Tonight

[Dec 27 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2025-12-27&endDate=2025-12-28&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Tomorrow

[Dec 28 - Dec 29](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2025-12-28&endDate=2025-12-29&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Next weekend

[Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2026-01-02&endDate=2026-01-04&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

In two weeks

[Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6059635&startDate=2026-01-09&endDate=2026-01-11&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

## Our top choices for Southern Indiana luxury hotels

![Front of property](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/a9b7038a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fountain](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/864ff441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/cef338e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/22b7d23e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 21c Museum Hotel Louisville

[](https://www.expedia.ca/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information)

Downtown Louisville

9.2/10

Wonderful

(1002)

"Staff was very kind, the art was fantastic, location was perfect to explore Whiskey Row, and we had a gorgeous room. Loved our time away there!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tammy

CA $190

CA $230 total

includes taxes & fees

Jan 1 - Jan 2, 2026

[](https://www.expedia.ca/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1750000/1745100/1745075/220feee7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Serves lunch and dinner](https://images.trvl-media.com/lodging/2000000/1750000/1745100/1745075/97ea6860.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1750000/1745100/1745075/bff88489.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![15 restaurants, breakfast served](https://images.trvl-media.com/lodging/2000000/1750000/1745100/1745075/95e75b78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### West Baden Springs Hotel

[](https://www.expedia.ca/West-Baden-Springs-Hotels-West-Baden-Springs-Hotel.h1745075.Hotel-Information)

West Baden Springs

9.6/10

Exceptional

(310)

"The hotel West Baden is awesome they have 24 hour trolley that runs every 15 minutes and will take you anywhere in the area."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anonymous traveller

[](https://www.expedia.ca/West-Baden-Springs-Hotels-West-Baden-Springs-Hotel.h1745075.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/840e31de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/3c2671ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/f0221042.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/2a2a7fb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Brown Hotel

[](https://www.expedia.ca/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information)

Downtown Louisville

9.4/10

Exceptional

(1162)

"Fantastic place to stay in Louisville."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nathaniel

CA $208

CA $245 total

includes taxes & fees

Dec 28 - Dec 29

[](https://www.expedia.ca/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information)

![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/b5c46c3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/594caae3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/23521baa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/ab0af7cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Galt House Hotel Trademark Collection by Wyndham

[](https://www.expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information)

Downtown Louisville

9.0/10

Wonderful

(3898)

"Great place to stay! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rochelle

CA $182

CA $214 total

includes taxes & fees

Jan 5 - Jan 6, 2026

[](https://www.expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information)

![Dinner served](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/e02820b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/c4d1fb67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/f30004bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/5bea9d61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Embassy Suites Louisville Downtown

[](https://www.expedia.ca/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information)

Downtown Louisville

9.0/10

Wonderful

(1125)

"Staff was courteous, hotel was beautiful and clean, and breakfast was amazing!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Shunskis

CA $167

CA $197 total

includes taxes & fees

Jan 11 - Jan 12, 2026

[](https://www.expedia.ca/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information)

![Standard Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/27100/27037/1942d798.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/27100/27037/c90e9ace.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/27100/27037/0b818ec5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/27100/27037/bea3ec0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Econo Lodge Louisville Downtown

[](https://www.expedia.ca/Louisville-Hotels-Econo-Lodge-Downtown-Louisville.h27037.Hotel-Information)

Downtown Louisville

7.2/10

Good

(1005)

"Nice hotel with a great location near Whiskey Row. This is my 3rd stay at this hotel and will definitely come back again"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nicholas

CA $86

CA $101 total

includes taxes & fees

Jan 9 - Jan 10, 2026

[](https://www.expedia.ca/Louisville-Hotels-Econo-Lodge-Downtown-Louisville.h27037.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/3d017cc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/aa5a75a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/12e6fe89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/e898c223.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Seelbach Hilton Louisville Downtown

[](https://www.expedia.ca/Louisville-Hotels-The-Seelbach-Hilton-Louisville.h25958.Hotel-Information)

Downtown Louisville

8.6/10

Excellent

(1003)

"Excellent location and a great lobby bar with a top notch bourbon selection. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

vincent

CA $193

CA $227 total

includes taxes & fees

Dec 29 - Dec 30

[](https://www.expedia.ca/Louisville-Hotels-The-Seelbach-Hilton-Louisville.h25958.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/1000000/70000/67700/67603/48eca275.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/70000/67700/67603/d973f209.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/70000/67700/67603/w391h300x0y0-9ca648dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/70000/67700/67603/d2a7092d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Baymont by Wyndham Corydon

[](https://www.expedia.ca/Corydon-Hotels-Baymont-By-Wyndham-Corydon.h67603.Hotel-Information)

Corydon

7.6/10

Good

(999)

"Always a great place to stay for the price."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sidney

CA $92

CA $102 total

includes taxes & fees

Jan 4 - Jan 5, 2026

[](https://www.expedia.ca/Corydon-Hotels-Baymont-By-Wyndham-Corydon.h67603.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/6000000/5810000/5801000/5800938/5fef5386.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/6000000/5810000/5801000/5800938/c60e0e07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down comforters, pillowtop beds, desk](https://images.trvl-media.com/lodging/6000000/5810000/5801000/5800938/3040b0bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/6000000/5810000/5801000/5800938/0e84f1cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Courtyard by Marriott Evansville East

[](https://www.expedia.ca/Evansville-Hotels-Courtyard-By-Marriott-Evansville-East.h5800938.Hotel-Information)

Evansville

8.8/10

Excellent

(1000)

"Clean and comfortable! Loved everything about it."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Maureen

CA $190

CA $219 total

includes taxes & fees

Dec 28 - Dec 29

[](https://www.expedia.ca/Evansville-Hotels-Courtyard-By-Marriott-Evansville-East.h5800938.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21200/21199/6e350e03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21200/21199/9ed272c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Individually furnished, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/21200/21199/b9a48afc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/1000000/30000/21200/21199/de60209a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Travelodge by Wyndham Sellersburg / Louisville North

[](https://www.expedia.ca/Sellersburg-Hotels-Travelodge-By-Wyndham-Sellersburg-Louisville-North.h21199.Hotel-Information)

Sellersburg

6.6/10

(701)

"Room was nice n clean, however checkout is 1100 am , house cleaning seems to be in a hurry to get u outta there, they knocking on the Door at 930, this has happened several times to me."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Curtis

CA $92

CA $104 total

includes taxes & fees

Jan 3 - Jan 4, 2026

[](https://www.expedia.ca/Sellersburg-Hotels-Travelodge-By-Wyndham-Sellersburg-Louisville-North.h21199.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-10&endDate=2026-01-11&regionId=6059635&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true)

## Top Southern Indiana Hotel Reviews

![Hampton Inn New Albany Louisville West](https://images.trvl-media.com/lodging/1000000/30000/25400/25301/eb53eba8_y.jpg)

### Hampton Inn New Albany Louisville West

10/10 Excellent

"yes, room was ok. staff good. the next mornings was a problem was the shower curtain. it was not tall enough to stop the water from flooding down to the toilet. this room 218 is a wheel chair room. I cleaned up the water as best I could. the shower curtain was not tall enough to touch the small roll over barirer for a wheelchair person. I reported tjis to the front desk. the stay is always good."

[](https://expedia.ca/Louisville-Hotels-Hampton-Inn-New-Albany-Louisville-West.h25301.Hotel-Information)

![Best Western Green Tree Inn](https://images.trvl-media.com/lodging/1000000/30000/21100/21059/80ec0958_y.jpg)

### Best Western Green Tree Inn

10/10 Excellent

"Yes "

[](https://expedia.ca/Louisville-Hotels-Best-Western-Green-Tree-Inn.h21059.Hotel-Information)

![Sheraton Louisville Riverside by Marriott](https://images.trvl-media.com/lodging/1000000/20000/17900/17862/14fa367c_y.jpg)

### Sheraton Louisville Riverside by Marriott

10/10 Excellent

"Staff was extremely friendly, helpful, and just exceptional all around. From check in to leaving the building we were greeted with kindness. Tim in club level was so kind and funny! I will definitely be staying here again, instead of the Galt House. "

[](https://expedia.ca/Louisville-Hotels-Sheraton-Louisville-Riverside-Hotel.h17862.Hotel-Information)

![Hampton Inn Evansville/Airport](https://images.trvl-media.com/lodging/1000000/20000/10200/10106/3300406a_y.jpg)

### Hampton Inn Evansville/Airport

10/10 Excellent

"Enjoyed our one night stay"

[](https://expedia.ca/Evansville-Hotels-Hampton-Inn-EvansvilleAirport.h10106.Hotel-Information)

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