Title: Book the Best Southwest LUXURY Hotels - Upscale Hotels in Southwest, MS | Expedia.ca [Southwest Travel Guide](https://expedia.ca/Southwest.dx6058704)[Hotels in Southwest](https://expedia.ca/Southwest-Hotels.d6058704.Travel-Guide-Hotels)[Vacation Rentals in Southwest](https://expedia.ca/Southwest-Vacation-Rentals.d6058704.Travel-Guide-VacationRentals)[Flights to Southwest](https://expedia.ca/Cheap-Flights-To-Southwest.d6058704.Travel-Guide-Flights)[Things to do in Southwest](https://expedia.ca/Things-To-Do-In-Southwest.d6058704.Travel-Guide-Activities)[Southwest Car Rentals](https://expedia.ca/Car-Rentals-In-Southwest.d6058704.Car-Rental-Guide)[Southwest Vacation Packages](https://expedia.ca/Southwest.d6058704.Destination-Travel-Guides) ![Jackson which includes interior views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/26000/26231-Jackson.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Southwest, MS ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southwest Luxury Hotels Tonight [Oct 5 - Oct 6](https://www.expedia.ca/Hotel-Search?regionId=6058704&startDate=2025-10-05&endDate=2025-10-06&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 6 - Oct 7](https://www.expedia.ca/Hotel-Search?regionId=6058704&startDate=2025-10-06&endDate=2025-10-07&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6058704&startDate=2025-10-10&endDate=2025-10-12&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6058704&startDate=2025-10-17&endDate=2025-10-19&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Southwest Luxury Hotels ![Pillowtop beds, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/19900/19806/863fd184.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed (John R. Lynch)](https://images.trvl-media.com/lodging/1000000/20000/19900/19806/1506f9c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed (The Newman Room)](https://images.trvl-media.com/lodging/1000000/20000/19900/19806/e3fdc006.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19900/19806/28652090.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Guest House Historic Mansion Natchez 9.2/10 Wonderful (808) "The location is great for seeing historic Natchez. " [](https://www.expedia.ca/Natchez-Hotels-The-Guest-House-Historic-Mansion.h19806.Hotel-Information) ![Courtyard view](https://images.trvl-media.com/lodging/13000000/12510000/12504700/12504628/734bdf2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/13000000/12510000/12504700/12504628/feeed2eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pemberton Suite | Living area](https://images.trvl-media.com/lodging/13000000/12510000/12504700/12504628/acb5378a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/13000000/12510000/12504700/12504628/0d1b6c51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Duff Green Mansion Vicksburg 9.4/10 Exceptional (921) "It was quiet and relaxing. The staff was very accommodating and friendly. Loved the house " CA $233 CA $256 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Vicksburg-Hotels-Duff-Green-Mansion.h12504628.Hotel-Information) ![Free full breakfast](https://images.trvl-media.com/lodging/1000000/20000/13700/13681/a9ebe183.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave](https://images.trvl-media.com/lodging/1000000/20000/13700/13681/w3836h2563x4y0-4f589984.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/20000/13700/13681/w3837h2560x3y3-3774776c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/13700/13681/w3837h2563x3y0-01a8f5ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Airport Inn Pearl 7.8/10 Good (1000) "Great service every time I stay!" CA $95 CA $106 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/Jackson-Hotels-Best-Western-Airport-Inn.h13681.Hotel-Information) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/25900/25813/45ca9f10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25900/25813/384b786c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/25900/25813/a7f87e61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/25900/25813/389bc9c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Vicksburg Vicksburg 7.4/10 Good (1001) "We had a wonderful stay. " CA $91 CA $100 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Vicksburg-Hotels-Econo-Lodge-Vicksburg.h25813.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/16000000/15810000/15800200/15800156/ce08d92c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Room, 1 Queen Bed (Misses Steele's Bedroom)](https://images.trvl-media.com/lodging/16000000/15810000/15800200/15800156/3d38dfc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/16000000/15810000/15800200/15800156/e4b67479.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/16000000/15810000/15800200/15800156/cb45ed1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Steele Cottage Vicksburg 8.8/10 Excellent (170) "Beautiful house with history. " CA $157 CA $169 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Vicksburg-Hotels-Steele-Cottage.h15800156.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/3000000/2210000/2202800/2202701/500d628e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/3000000/2210000/2202800/2202701/a4ee26d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2210000/2202800/2202701/0cb4587e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2210000/2202800/2202701/59199198.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Canton MS Canton 7.2/10 Good (641) "Great affordable place to stay. " CA $151 CA $164 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Canton-MS.h2202701.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1790000/1788900/1788807/574d9394.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/2000000/1790000/1788900/1788807/15c2b6d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1790000/1788900/1788807/c1dfb479.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1790000/1788900/1788807/d6203f85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Natchez Grand Hotel & Suites On the River Natchez 8.6/10 Excellent (1336) "Had a very nice stay would recamend." CA $166 CA $218 total includes taxes & fees Oct 6 - Oct 7 [](https://www.expedia.ca/Natchez-Hotels-Natchez-Grand-Hotel-Suites-On-The-River.h1788807.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3060000/3050200/3050127/e8740bc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3060000/3050200/3050127/fb1fb1a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3060000/3050200/3050127/f888e18f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3060000/3050200/3050127/3c612518.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Jackson Downtown Downtown Jackson 7.2/10 Good (1002) "Love staying here" CA $122 CA $136 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Jackson-Hotels-Hilton-Garden-Inn-Jackson-Downtown.h3050127.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8100/8071/ed94bf8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/8100/8071/844b8806.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/8100/8071/5640696e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/8100/8071/a0e8ebfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Vicksburg Vicksburg 8.6/10 Excellent (1004) "Clean room, courteous staff, excellent breakfast " CA $147 CA $162 total includes taxes & fees Oct 9 - Oct 10 [](https://www.expedia.ca/Vicksburg-Hotels-Best-Western-Vicksburg.h8071.Hotel-Information) ![1 bedroom, iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/490000/484100/484003/1d201c1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/490000/484100/484003/e146d3b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/490000/484100/484003/8076022e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/490000/484100/484003/f3620080.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Vicksburg Vicksburg 7.4/10 Good (1003) "Nice place, would use again" CA $102 CA $112 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Vicksburg-Hotels-Quality-Inn-Vicksburg.h484003.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-19&endDate=2025-10-20®ionId=6058704&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Top Southwest Hotel Reviews ![Prado Hotel](//images.trvl-media.com/lodging/1000000/900000/891200/891169/b960ab9a_y.jpg) ### Prado Hotel 10/10 Excellent "Everyone at this hotel was sweet and considerate of me being alone with my son and needing extra hands to carry things. Just very kind and we will be back because of this. " [](https://expedia.ca/Jackson-Hotels-Drury-Inn-Suites-Jackson-Ridgeland.h891169.Hotel-Information) ![Quality Inn & Suites Pearl - Jackson](//images.trvl-media.com/lodging/1000000/980000/973600/973518/72981665_y.jpg) ### Quality Inn & Suites Pearl - Jackson 10/10 Excellent "It was a nice place to stay. It was clean." [](https://expedia.ca/Jackson-Hotels-Quality-Inn-Suites-Pearl-Jackson.h973518.Hotel-Information) ![Baymont by Wyndham Jackson/Ridgeland](//images.trvl-media.com/lodging/1000000/540000/537200/537157/7b452194_y.jpg) ### Baymont by Wyndham Jackson/Ridgeland 10/10 Excellent "Great place. Great Communication. Easy check in and check out. " [](https://expedia.ca/Jackson-Hotels-Baymont-By-Wyndham-JacksonRidgeland.h537157.Hotel-Information) ![Hilton Garden Inn Jackson Downtown](//images.trvl-media.com/lodging/4000000/3060000/3050200/3050127/e8740bc4_y.jpg) ### Hilton Garden Inn Jackson Downtown 10/10 Excellent "Clean room " [](https://expedia.ca/Jackson-Hotels-Hilton-Garden-Inn-Jackson-Downtown.h3050127.Hotel-Information) ![Natchez Grand Hotel & Suites On the River](//images.trvl-media.com/lodging/2000000/1790000/1788900/1788807/574d9394_y.jpg) ### Natchez Grand Hotel & Suites On the River 10/10 Excellent "Room could have been cleaner - tile flooring was sticky and carpet wasn’t cleaned thoroughly. Tile in bathroom was chipped and grout was missing in many places. Would not walk barefoot in the bathroom out of fear of cutting feet, but I always bring sandals to wear in hotels anyways. Service was excellent at front desk and breakfast. Hotel is centrally located with many restaurants and shops in walking distance. Would stay here again. " [](https://expedia.ca/Natchez-Hotels-Natchez-Grand-Hotel-Suites-On-The-River.h1788807.Hotel-Information) ![Ameristar Casino Hotel Vicksburg](//images.trvl-media.com/lodging/3000000/2520000/2516400/2516319/46e018b6_y.jpg) ### Ameristar Casino Hotel Vicksburg 10/10 Excellent "It’s a small town with a casino. The people are nice. Eat at Tommy’s bbq" [](https://expedia.ca/Vicksburg-Hotels-Ameristar-Casino-Hotel-Vicksburg.h2516319.Hotel-Information) ![Days Inn by Wyndham Natchez](//images.trvl-media.com/lodging/1000000/20000/11200/11184/301a51d1_y.jpg) ### Days Inn by Wyndham Natchez 10/10 Excellent "Pet friendly/parking/breakfast/air conditioned. We will stay there again in a month." 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