Title: 10 Best Hotels in South Main, Houston for 2025 | Expedia.ca

 

[Vacation Rentals in Houston](https://expedia.ca/Houston-Vacation-Rentals.d178265.Travel-Guide-VacationRentals)[Flights to Houston](https://expedia.ca/Cheap-Flights-To-Houston.d178265.Travel-Guide-Flights)[Things to do in Houston](https://expedia.ca/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities)[South Main Car Rentals](https://expedia.ca/Car-Rentals-In-South-Main.d553248635976386992.Car-Rental-Guide)[South Main Vacations](https://expedia.ca/South-Main.d553248635976386992.Destination-Travel-Guides)

![](https://images.trvl-media.com/place/1503/2eeb9f80-ebf6-42ad-9574-1d77038420db.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Hotels in South Main, Houston

-   ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg)
    
    ### 
    
    Change your mind
    
    Book hotels with free cancellation
    
-   ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg)
    
    ### 
    
    Treat yourself
    
    Sign in to save 10% or more on thousands of hotels
    
    [Sign in](https://www.expedia.ca/login)
    
-   ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg)
    
    ### 
    
    Be picky
    
    Search almost a million properties worldwide
    

## Go beyond your typical stay in South Main

Apart hotel

[](https://www.expedia.ca/Hotel-Search?destination=South+Main%2C+Houston%2C+Texas%2C+United+States+of+America&regionId=553248635976386992&latLong=29.67287%2C-95.418071&adults=2&startDate=2025-11-14&d1=2025-11-14&endDate=2025-11-16&d2=2025-11-16&lodging=APART_HOTEL)

Apart­ment

[](https://www.expedia.ca/Hotel-Search?destination=South+Main%2C+Houston%2C+Texas%2C+United+States+of+America&regionId=553248635976386992&latLong=29.67287%2C-95.418071&adults=2&startDate=2025-11-14&d1=2025-11-14&endDate=2025-11-16&d2=2025-11-16&lodging=APARTMENT)

Family friendly

[](https://www.expedia.ca/Hotel-Search?destination=South+Main%2C+Houston%2C+Texas%2C+United+States+of+America&regionId=553248635976386992&latLong=29.67287%2C-95.418071&adults=2&startDate=2025-11-14&d1=2025-11-14&endDate=2025-11-16&d2=2025-11-16&travelerType=family_friendly)

Cottage

[](https://www.expedia.ca/Hotel-Search?destination=South+Main%2C+Houston%2C+Texas%2C+United+States+of+America&regionId=553248635976386992&latLong=29.67287%2C-95.418071&adults=2&startDate=2025-11-14&d1=2025-11-14&endDate=2025-11-16&d2=2025-11-16&lodging=COTTAGE)

Pool

[](https://www.expedia.ca/Hotel-Search?destination=South+Main%2C+Houston%2C+Texas%2C+United+States+of+America&regionId=553248635976386992&latLong=29.67287%2C-95.418071&adults=2&startDate=2025-11-14&d1=2025-11-14&endDate=2025-11-16&d2=2025-11-16&amenities=POOL)

Condo

[](https://www.expedia.ca/Hotel-Search?destination=South+Main%2C+Houston%2C+Texas%2C+United+States+of+America&regionId=553248635976386992&latLong=29.67287%2C-95.418071&adults=2&startDate=2025-11-14&d1=2025-11-14&endDate=2025-11-16&d2=2025-11-16&lodging=CONDO)

Hot tub

[](https://www.expedia.ca/Hotel-Search?destination=South+Main%2C+Houston%2C+Texas%2C+United+States+of+America&regionId=553248635976386992&latLong=29.67287%2C-95.418071&adults=2&startDate=2025-11-14&d1=2025-11-14&endDate=2025-11-16&d2=2025-11-16&amenities=HOT_TUB)

Pet friendly

[](https://www.expedia.ca/Hotel-Search?destination=South+Main%2C+Houston%2C+Texas%2C+United+States+of+America&regionId=553248635976386992&latLong=29.67287%2C-95.418071&adults=2&startDate=2025-11-14&d1=2025-11-14&endDate=2025-11-16&d2=2025-11-16&amenities=PETS)

Waterpark

[](https://www.expedia.ca/Hotel-Search?destination=South+Main%2C+Houston%2C+Texas%2C+United+States+of+America&regionId=553248635976386992&latLong=29.67287%2C-95.418071&adults=2&startDate=2025-11-14&d1=2025-11-14&endDate=2025-11-16&d2=2025-11-16&amenities=WATER_PARK)

Spa

[](https://www.expedia.ca/Hotel-Search?destination=South+Main%2C+Houston%2C+Texas%2C+United+States+of+America&regionId=553248635976386992&latLong=29.67287%2C-95.418071&adults=2&startDate=2025-11-14&d1=2025-11-14&endDate=2025-11-16&d2=2025-11-16&amenities=SPA_ON_SITE)

Villa

[](https://www.expedia.ca/Hotel-Search?destination=South+Main%2C+Houston%2C+Texas%2C+United+States+of+America&regionId=553248635976386992&latLong=29.67287%2C-95.418071&adults=2&startDate=2025-11-14&d1=2025-11-14&endDate=2025-11-16&d2=2025-11-16&lodging=VILLA)

## Check prices for these dates

Tonight

[Oct 31 - Nov 1](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2025-10-31&endDate=2025-11-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Nov 1 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2025-11-01&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## South Main hotels and places to stay

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/w2558h1440x0y0-44773629.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Ballroom](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/63833027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Food and drink](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/83265e97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pet-friendly](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/982edefb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Wyndham Houston near NRG Park/Medical Center

South Main

7.2/10

Good

(1179)

"Everyone was very pleasant, I will be returning."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Amy

CA $138

CA $162 total

includes taxes & fees

Nov 6 - Nov 7

[](https://www.expedia.ca/Houston-Hotels-Wyndham-Houston-Near-NRG-ParkMedical-Center.h21297.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/910000/904200/904192/0afdb877.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/910000/904200/904192/a1271476.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Individually decorated, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/910000/904200/904192/d9a5db5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/910000/904200/904192/28e82f54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Suites Houston near Medical Center- NRG Stadium

South Main

8.6/10

Excellent

(1005)

"Nice room. No pot smell. It was great. Bed was comfortable and it had a REAL comforter not some cheap blanket! Would stay here again. 😊"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

cindy

CA $118

CA $138 total

includes taxes & fees

Nov 17 - Nov 18

[](https://www.expedia.ca/Houston-Hotels-Comfort-Suites-Near-Texas-Medical-Center-NRG-Stadium.h904192.Hotel-Information)

![1 bedroom, hypo-allergenic bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/20000/17600/17531/3135be14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, hypo-allergenic bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/20000/17600/17531/572f60ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/17600/17531/1e7f9dd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/17600/17531/b55cbe72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn & Suites NRG Park - Medical Center

South Main

6.6/10

(1002)

"Everything was great"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Yeimi

CA $82

CA $96 total

includes taxes & fees

Dec 1 - Dec 2

[](https://www.expedia.ca/Houston-Hotels-Quality-Inn-Suites-NRG-Park-Medical-Center.h17531.Hotel-Information)

![Gazebo](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/ab4b9445.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/bdf24163.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/98547457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/6b2e094a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Wingate Houston near NRG Park/Medical Center

South Main

6.6/10

(955)

"We got to our room and it wide open …… we tried to call the front guest phones didn’t work …. We went down and only had one person working ….. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Eduardo

CA $110

CA $129 total

includes taxes & fees

Nov 6 - Nov 7

[](https://www.expedia.ca/Houston-Hotels-Wingate-By-Wyndham-Houston-Reliant-Medical-Center.h66022895.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/168bdeac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/13fb2418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full-size fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/14da1a00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/27e929b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Candlewood Suites Houston Medical Center by IHG

South Main

7.4/10

Good

(807)

"Room was clean and roomy. The toilet height was too low. Staff was friendly and professional."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Willie

CA $103

CA $121 total

includes taxes & fees

Nov 3 - Nov 4

[](https://www.expedia.ca/Houston-Hotels-Candlewood-Suites-Houston-Medical-Center.h2227000.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/13300/13295/c40a6103.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/13300/13295/dd9a3669.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/13300/13295/077747b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite (Composer) | Dining room](https://images.trvl-media.com/lodging/1000000/20000/13300/13295/f9f8ae11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Lancaster Hotel

Downtown Houston, 11.1 km from South Main

9.8/10

Exceptional

(1004)

"Friendly staff, comfortable bed, great breakfast."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Polly Gay

CA $281

CA $329 total

includes taxes & fees

Nov 21 - Nov 22

[](https://www.expedia.ca/Houston-Hotels-The-Lancaster-Hotel.h13295.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/89000000/88140000/88130500/88130440/a6f86b3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/89000000/88140000/88130500/88130440/6748ac8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/89000000/88140000/88130500/88130440/eec7b544.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/89000000/88140000/88130500/88130440/71ab7d99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Place Houston Medical Center

Texas Medical Center, 3.1 km from South Main

9.2/10

Wonderful

(2077)

"Excellent place to stay very clean great customer service!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Monica

CA $165

CA $194 total

includes taxes & fees

Nov 28 - Nov 29

[](https://www.expedia.ca/Houston-Hotels-Hyatt-Place-Houston-Medical-Center.h88130440.Hotel-Information)

![Outdoor pool, open 6:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/11000000/10630000/10620700/10620692/9a708987.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, hypo-allergenic bedding, in-room safe, desk](https://images.trvl-media.com/lodging/11000000/10630000/10620700/10620692/e4ab6d84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, hypo-allergenic bedding, in-room safe, desk](https://images.trvl-media.com/lodging/11000000/10630000/10620700/10620692/55e246fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/11000000/10630000/10620700/10620692/5138e12a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Regency Houston/Galleria

The Galleria, 8.7 km from South Main

9.0/10

Wonderful

(1119)

"Wonderful property!!! Very much enjoyed our stay! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Matthew

CA $189

CA $222 total

includes taxes & fees

Nov 23 - Nov 24

[](https://www.expedia.ca/Houston-Hotels-Hyatt-Regency-HoustonGalleria.h10620692.Hotel-Information)

![Exterior detail](https://images.trvl-media.com/lodging/1000000/30000/20200/20116/555244ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/30000/20200/20116/ec3f4d74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, down comforters, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/1000000/30000/20200/20116/71078c26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, down comforters, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/1000000/30000/20200/20116/d7c28c50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### DoubleTree by Hilton Hotel & Suites Houston by the Galleria

8.9 km from South Main

8.2/10

Very good

(2791)

"Nice stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Corey

CA $138

CA $162 total

includes taxes & fees

Nov 29 - Nov 30

[](https://www.expedia.ca/Houston-Hotels-DoubleTree-By-Hilton-Hotel-Suites-Houston-By-The-Galleria.h20116.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/84000000/83760000/83751000/83750993/31c2b88f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/84000000/83760000/83751000/83750993/f81e2b4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/84000000/83760000/83751000/83750993/47f50537.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/84000000/83760000/83751000/83750993/1d77a540.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt House Houston Medical Center

Texas Medical Center, 3.1 km from South Main

9.2/10

Wonderful

(1150)

"Great stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kurt

CA $165

CA $194 total

includes taxes & fees

Nov 28 - Nov 29

[](https://www.expedia.ca/Houston-Hotels-Hyatt-House-Houston-Medical-Center.h83750993.Hotel-Information)

![City view from property](https://images.trvl-media.com/lodging/1000000/700000/693700/693655/f1d85056.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/700000/693700/693655/f3f90eac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor wedding](https://images.trvl-media.com/lodging/1000000/700000/693700/693655/ebaa4874.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/700000/693700/693655/e16d70bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Whitehall Houston

Houston Central Business District, 10 km from South Main

8.6/10

Excellent

(1839)

"Great staff nice rooms"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Matthew

CA $178

CA $208 total

includes taxes & fees

Nov 21 - Nov 22

[](https://www.expedia.ca/Houston-Hotels-The-Whitehall-Houston.h693655.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/dc9d050c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![50-inch Smart TV with cable channels, TV, Netflix](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/w3836h2556x4y4-af1501b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, premium bedding, minibar, in-room safe](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/40a5bc26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/a72ac5b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Blossom Hotel Houston, Curio Collection by Hilton

Texas Medical Center, 3.5 km from South Main

9.0/10

Wonderful

(3599)

"Clean friendly staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alfreida

CA $174

CA $204 total

includes taxes & fees

Nov 29 - Nov 30

[](https://www.expedia.ca/Houston-Hotels-Blossom-Hotel-Houston.h58985846.Hotel-Information)

![Breakfast, lunch, brunch served; American cuisine, garden views ](https://images.trvl-media.com/lodging/1000000/20000/12400/12378/7e4ad465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/12400/12378/729ec87e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12400/12378/880627d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12400/12378/06b8ac16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Regency Houston West

23.2 km from South Main

8.6/10

Excellent

(1218)

"Beautiful lobby and friendly staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Laura

CA $175

CA $205 total

includes taxes & fees

Nov 9 - Nov 10

[](https://www.expedia.ca/Houston-Hotels-Hyatt-Regency-Houston-West.h12378.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/9874e960.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, Egyptian cotton sheets, premium bedding, pillowtop beds](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/w3836h2556x4y4-d736e03c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Staircase](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/5506d9bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/b032cc4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Royal Sonesta Houston Galleria

The Galleria, 8.8 km from South Main

8.4/10

Very good

(1337)

"Great stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jennifer

CA $166

CA $194 total

includes taxes & fees

Nov 29 - Nov 30

[](https://www.expedia.ca/Houston-Hotels-Royal-Sonesta-Houston-Galleria.h878652.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/67000000/66430000/66425800/66425729/8293c765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/67000000/66430000/66425800/66425729/c4f24f6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/67000000/66430000/66425800/66425729/cadce26d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Snack bar](https://images.trvl-media.com/lodging/67000000/66430000/66425800/66425729/b3a01060.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Garden Inn Houston Medical Center, TX

Texas Medical Center, 4.7 km from South Main

9.4/10

Exceptional

(999)

"Great hotel and location!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gonzalo

CA $143

CA $168 total

includes taxes & fees

Nov 27 - Nov 28

[](https://www.expedia.ca/Houston-Hotels-Hilton-Garden-Inn-Houston-Medical-Center.h66425729.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/24000000/23840000/23830900/23830866/e83f776d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/24000000/23840000/23830900/23830866/5f5e8d93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/24000000/23840000/23830900/23830866/29e4bd94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/24000000/23840000/23830900/23830866/efa6f907.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### InterContinental Houston by IHG

Texas Medical Center, 4.1 km from South Main

9.2/10

Wonderful

(1001)

"Very well maintenance property, beautiful lobby and friendly staff."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Viji

CA $194

CA $255 total

includes taxes & fees

Nov 28 - Nov 29

[](https://www.expedia.ca/Houston-Hotels-InterContinental-Houston-Medical-Center.h23830866.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/44a9a3fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/76e7278c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/c1fa2b90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/aa7fafd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Club Quarters Hotel Downtown, Houston

Houston Central Business District, 10.9 km from South Main

8.4/10

Very good

(3849)

"Stay was great, check in was very easy and it was in a great location "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kristianna

CA $122

CA $143 total

includes taxes & fees

Nov 22 - Nov 23

[](https://www.expedia.ca/Houston-Hotels-Club-Quarters-Hotel-In-Houston.h1156923.Hotel-Information)

![Premium bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/19000000/18130000/18122200/18122141/e02c73c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/19000000/18130000/18122200/18122141/8863ac84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/19000000/18130000/18122200/18122141/18c0750c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily full breakfast](https://images.trvl-media.com/lodging/19000000/18130000/18122200/18122141/be7d736f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Haven Inn & Suites Downtown Houston

North Houston, 18.8 km from South Main

9.4/10

Exceptional

(1004)

"Very clean and safe, would stay again"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Krimson

[](https://www.expedia.ca/Houston-Hotels-Haven-Inn-Suites-Downtown-Houston.h18122141.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/33000000/32710000/32701900/32701841/ac108c4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/33000000/32710000/32701900/32701841/58604b02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/33000000/32710000/32701900/32701841/0ca2f795.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/33000000/32710000/32701900/32701841/532fe87e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Houston - Memorial City Centre by IHG

18.4 km from South Main

8.8/10

Excellent

(1006)

"Clean, friendly staff, good breakfast, and all around great stay! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rebecca

CA $161

CA $189 total

includes taxes & fees

Nov 9 - Nov 10

[](https://www.expedia.ca/Houston-Hotels-Holiday-Inn-Express-Suites-Houston-Memorial-City-Centre.h32701841.Hotel-Information)

![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/30000/28100/28060/38218191.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Serves breakfast, lunch, and dinner](https://images.trvl-media.com/lodging/1000000/30000/28100/28060/9a6615c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/28100/28060/4aed2271.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/28100/28060/5d436540.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Crowne Plaza Houston Med Ctr-Galleria Area by IHG

6.5 km from South Main

7.6/10

Good

(1164)

"Great hotel for the price! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Adriana

CA $93

CA $109 total

includes taxes & fees

Nov 3 - Nov 4

[](https://www.expedia.ca/Houston-Hotels-Crowne-Plaza-Houston-River-Oaks.h28060.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-14&endDate=2025-11-15&regionId=553248635976386992&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Hotels in South Main with free breakfast

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/w2558h1440x0y0-44773629.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Ballroom](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/63833027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Food and drink](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/83265e97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pet-friendly](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/982edefb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Wyndham Houston near NRG Park/Medical Center

South Main

-   Breakfast included
    

7.2/10

Good

(1179)

CA $138

CA $162 total

includes taxes & fees

Nov 6 - Nov 7

[](https://www.expedia.ca/Hotel-Search?startDate=2025-11-06&endDate=2025-11-07&selected=21297&PinnedHotelID=21297&HadPinnedHotel=true&regionId=553248635976386992&adults=2&mealPlan=FREE_BREAKFAST&openPlayBack=true)

![Lobby](https://images.trvl-media.com/lodging/1000000/910000/904200/904192/0afdb877.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/910000/904200/904192/a1271476.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Individually decorated, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/910000/904200/904192/d9a5db5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/910000/904200/904192/28e82f54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Suites Houston near Medical Center- NRG Stadium

South Main

-   Breakfast included
    

8.6/10

Excellent

(1005)

CA $118

CA $138 total

includes taxes & fees

Nov 17 - Nov 18

[](https://www.expedia.ca/Hotel-Search?startDate=2025-11-17&endDate=2025-11-18&selected=904192&PinnedHotelID=904192&HadPinnedHotel=true&regionId=553248635976386992&adults=2&mealPlan=FREE_BREAKFAST&openPlayBack=true)

![Gazebo](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/ab4b9445.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/bdf24163.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/98547457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/6b2e094a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Wingate Houston near NRG Park/Medical Center

South Main

-   Breakfast included
    

6.6/10

(955)

CA $110

CA $129 total

includes taxes & fees

Nov 6 - Nov 7

[](https://www.expedia.ca/Hotel-Search?startDate=2025-11-06&endDate=2025-11-07&selected=66022895&PinnedHotelID=66022895&HadPinnedHotel=true&regionId=553248635976386992&adults=2&mealPlan=FREE_BREAKFAST&openPlayBack=true)

![1 bedroom, hypo-allergenic bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/20000/17600/17531/3135be14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, hypo-allergenic bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/20000/17600/17531/572f60ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/17600/17531/1e7f9dd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/17600/17531/b55cbe72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn & Suites NRG Park - Medical Center

South Main

-   Breakfast included
    

6.6/10

(1002)

CA $82

CA $96 total

includes taxes & fees

Dec 1 - Dec 2

[](https://www.expedia.ca/Hotel-Search?startDate=2025-12-01&endDate=2025-12-02&selected=17531&PinnedHotelID=17531&HadPinnedHotel=true&regionId=553248635976386992&adults=2&mealPlan=FREE_BREAKFAST&openPlayBack=true)

![Lobby](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/44a9a3fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/76e7278c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/c1fa2b90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/aa7fafd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Club Quarters Hotel Downtown, Houston

Houston Central Business District, 10.9 km from South Main

-   Breakfast included
    

8.4/10

Very good

(3849)

CA $122

CA $143 total

includes taxes & fees

Nov 22 - Nov 23

[](https://www.expedia.ca/Hotel-Search?startDate=2025-11-22&endDate=2025-11-23&selected=1156923&PinnedHotelID=1156923&HadPinnedHotel=true&regionId=553248635976386992&adults=2&mealPlan=FREE_BREAKFAST&openPlayBack=true)

![Property amenity](https://images.trvl-media.com/lodging/9000000/8170000/8168200/8168134/f5ea3a06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/9000000/8170000/8168200/8168134/5de16016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/9000000/8170000/8168200/8168134/52dcd712.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/9000000/8170000/8168200/8168134/f95e9509.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Houston Downtown by IHG

Houston Central Business District, 10 km from South Main

-   Breakfast included
    

8.8/10

Excellent

(1510)

CA $108

CA $134 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Hotel-Search?startDate=2025-11-30&endDate=2025-12-01&selected=8168134&PinnedHotelID=8168134&HadPinnedHotel=true&regionId=553248635976386992&adults=2&mealPlan=FREE_BREAKFAST&openPlayBack=true)

![Exterior detail](https://images.trvl-media.com/lodging/1000000/30000/20200/20116/555244ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/30000/20200/20116/ec3f4d74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, down comforters, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/1000000/30000/20200/20116/71078c26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, down comforters, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/1000000/30000/20200/20116/d7c28c50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### DoubleTree by Hilton Hotel & Suites Houston by the Galleria

8.9 km from South Main

-   Breakfast included
    

8.2/10

Very good

(2791)

CA $138

CA $162 total

includes taxes & fees

Nov 29 - Nov 30

[](https://www.expedia.ca/Hotel-Search?startDate=2025-11-29&endDate=2025-11-30&selected=20116&PinnedHotelID=20116&HadPinnedHotel=true&regionId=553248635976386992&adults=2&mealPlan=FREE_BREAKFAST&openPlayBack=true)

![Outdoor pool, open 6:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/11000000/10630000/10620700/10620692/9a708987.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, hypo-allergenic bedding, in-room safe, desk](https://images.trvl-media.com/lodging/11000000/10630000/10620700/10620692/e4ab6d84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, hypo-allergenic bedding, in-room safe, desk](https://images.trvl-media.com/lodging/11000000/10630000/10620700/10620692/55e246fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/11000000/10630000/10620700/10620692/5138e12a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Regency Houston/Galleria

The Galleria, 8.7 km from South Main

-   Breakfast included
    

9.0/10

Wonderful

(1119)

CA $189

CA $222 total

includes taxes & fees

Nov 23 - Nov 24

[](https://www.expedia.ca/Hotel-Search?startDate=2025-11-23&endDate=2025-11-24&selected=10620692&PinnedHotelID=10620692&HadPinnedHotel=true&regionId=553248635976386992&adults=2&mealPlan=FREE_BREAKFAST&openPlayBack=true)

![Lobby sitting area](https://images.trvl-media.com/lodging/45000000/44400000/44399600/44399547/0c065c18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/45000000/44400000/44399600/44399547/40170516.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, Multiple Beds (High Floor)](https://images.trvl-media.com/lodging/45000000/44400000/44399600/44399547/fdf1a1ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lounge](https://images.trvl-media.com/lodging/45000000/44400000/44399600/44399547/c04e5fd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Place Houston Downtown

Houston Central Business District, 11 km from South Main

-   Breakfast included
    

9.0/10

Wonderful

(1563)

CA $158

CA $189 total

includes taxes & fees

Nov 24 - Nov 25

[](https://www.expedia.ca/Hotel-Search?startDate=2025-11-24&endDate=2025-11-25&selected=44399547&PinnedHotelID=44399547&HadPinnedHotel=true&regionId=553248635976386992&adults=2&mealPlan=FREE_BREAKFAST&openPlayBack=true)

![Lobby](https://images.trvl-media.com/lodging/36000000/35560000/35559700/35559679/82e8dff0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/36000000/35560000/35559700/35559679/096991ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/36000000/35560000/35559700/35559679/cfcd37d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/36000000/35560000/35559700/35559679/7f8ac21a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cambria Hotel Houston Downtown Convention Center

Houston Central Business District, 11 km from South Main

-   Breakfast included
    

8.8/10

Excellent

(1681)

CA $146

CA $170 total

includes taxes & fees

Nov 24 - Nov 25

[](https://www.expedia.ca/Hotel-Search?startDate=2025-11-24&endDate=2025-11-25&selected=35559679&PinnedHotelID=35559679&HadPinnedHotel=true&regionId=553248635976386992&adults=2&mealPlan=FREE_BREAKFAST&openPlayBack=true)

[See more properties](https://www.expedia.ca/Hotel-Search?startDate=2025-11-14&endDate=2025-11-15&regionId=553248635976386992&adults=2&sort=RECOMMENDED&mealPlan=FREE_BREAKFAST&openPlayBack=true)

## Hotels in South Main with a pool

![Sundeck](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/294f3d50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/8964faa3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor wedding area](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/f2e085ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/f8ddb5e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Houston Plaza/Medical Center

4.4 km from South Main

-   Pool
    

8.4/10

Very good

(1643)

CA $130

CA $154 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/Hotel-Search?startDate=2025-11-30&endDate=2025-12-01&selected=25188&PinnedHotelID=25188&HadPinnedHotel=true&regionId=553248635976386992&adults=2&amenities=POOL&openPlayBack=true)

![City view from property](https://images.trvl-media.com/lodging/1000000/700000/693700/693655/f1d85056.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/700000/693700/693655/f3f90eac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor wedding](https://images.trvl-media.com/lodging/1000000/700000/693700/693655/ebaa4874.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/700000/693700/693655/e16d70bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Whitehall Houston

Houston Central Business District, 10 km from South Main

-   Pool
    

8.6/10

Excellent

(1839)

CA $178

CA $208 total

includes taxes & fees

Nov 21 - Nov 22

[](https://www.expedia.ca/Hotel-Search?startDate=2025-11-21&endDate=2025-11-22&selected=693655&PinnedHotelID=693655&HadPinnedHotel=true&regionId=553248635976386992&adults=2&amenities=POOL&openPlayBack=true)

![Lunch and dinner served, Chinese cuisine](https://images.trvl-media.com/lodging/2000000/1160000/1156000/1155962/cc0b23d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/2000000/1160000/1156000/1155962/e7547f50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, hypo-allergenic bedding, desk, blackout drapes](https://images.trvl-media.com/lodging/2000000/1160000/1156000/1155962/2eba3fa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1160000/1156000/1155962/d6a44ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### ACP Hotel Houston Westchase, MOD Collection by Sonesta

13.6 km from South Main

-   Pool
    

8.0/10

Very good

(1002)

CA $105

CA $122 total

includes taxes & fees

Nov 3 - Nov 4

[](https://www.expedia.ca/Hotel-Search?startDate=2025-11-03&endDate=2025-11-04&selected=1155962&PinnedHotelID=1155962&HadPinnedHotel=true&regionId=553248635976386992&adults=2&amenities=POOL&openPlayBack=true)

[See more properties](https://www.expedia.ca/Hotel-Search?startDate=2025-11-14&endDate=2025-11-15&regionId=553248635976386992&adults=2&sort=RECOMMENDED&amenities=POOL&openPlayBack=true)

## Top guest rated hotels in South Main

![Exterior](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/168bdeac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/13fb2418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full-size fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/14da1a00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/27e929b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Candlewood Suites Houston Medical Center by IHG

South Main

7.4/10

Good

(807)

CA $103

CA $121 total

includes taxes & fees

Nov 3 - Nov 4

[](https://www.expedia.ca/Hotel-Search?startDate=2025-11-03&endDate=2025-11-04&selected=2227000&PinnedHotelID=2227000&HadPinnedHotel=true&regionId=553248635976386992&adults=2&guestRating=35&openPlayBack=true)

![Exterior](https://images.trvl-media.com/lodging/2000000/1560000/1558900/1558836/dea49ca8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/2000000/1560000/1558900/1558836/50af12ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![One King Studio Suite Non-Smoking](https://images.trvl-media.com/lodging/2000000/1560000/1558900/1558836/241f867c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/2000000/1560000/1558900/1558836/b27ae005.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn & Suites Houston-Bush Intercontinental Aprt

31.8 km from South Main

8.8/10

Excellent

(1614)

CA $101

CA $119 total

includes taxes & fees

Nov 17 - Nov 18

[](https://www.expedia.ca/Hotel-Search?startDate=2025-11-17&endDate=2025-11-18&selected=1558836&PinnedHotelID=1558836&HadPinnedHotel=true&regionId=553248635976386992&adults=2&guestRating=35&openPlayBack=true)

![Exclusive Room, Multiple Beds, Non Smoking](https://images.trvl-media.com/lodging/2000000/1250000/1240800/1240788/dcc5346d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1250000/1240800/1240788/557d86e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1250000/1240800/1240788/w800h584x0y0-b8e2ff5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/2000000/1250000/1240800/1240788/6c2cf751.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Platinum Inn & Suites Webster

30.8 km from South Main

7.8/10

Good

(1007)

CA $66

CA $78 total

includes taxes & fees

Nov 17 - Nov 18

[](https://www.expedia.ca/Hotel-Search?startDate=2025-11-17&endDate=2025-11-18&selected=1240788&PinnedHotelID=1240788&HadPinnedHotel=true&regionId=553248635976386992&adults=2&guestRating=35&openPlayBack=true)

![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2970000/2964300/2964240/69d373fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/3000000/2970000/2964300/2964240/1da2c869.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/3000000/2970000/2964300/2964240/1ef7d119.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2970000/2964300/2964240/6bc32cc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### SpringHill Suites by Marriott Houston Intercontinental Arprt

31.8 km from South Main

9.0/10

Wonderful

(1560)

CA $136

CA $159 total

includes taxes & fees

Nov 21 - Nov 22

[](https://www.expedia.ca/Hotel-Search?startDate=2025-11-21&endDate=2025-11-22&selected=2964240&PinnedHotelID=2964240&HadPinnedHotel=true&regionId=553248635976386992&adults=2&guestRating=35&openPlayBack=true)

![Courtyard](https://images.trvl-media.com/lodging/1000000/170000/165600/165562/0afb5a51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/1000000/170000/165600/165562/fa4ffa4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/170000/165600/165562/1eac58c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/170000/165600/165562/4382ed41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham Houston Bush IAH South

31.2 km from South Main

8.2/10

Very good

(996)

CA $96

CA $112 total

includes taxes & fees

Nov 3 - Nov 4

[](https://www.expedia.ca/Hotel-Search?startDate=2025-11-03&endDate=2025-11-04&selected=165562&PinnedHotelID=165562&HadPinnedHotel=true&regionId=553248635976386992&adults=2&guestRating=35&openPlayBack=true)

![Exterior](https://images.trvl-media.com/lodging/25000000/24160000/24152700/24152630/a3abdbe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/25000000/24160000/24152700/24152630/16a9741b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/25000000/24160000/24152700/24152630/d7f5d954.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Snack bar](https://images.trvl-media.com/lodging/25000000/24160000/24152700/24152630/97731659.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Garden Inn Houston Hobby Airport, TX

15 km from South Main

8.8/10

Excellent

(1005)

CA $101

CA $118 total

includes taxes & fees

Nov 23 - Nov 24

[](https://www.expedia.ca/Hotel-Search?startDate=2025-11-23&endDate=2025-11-24&selected=24152630&PinnedHotelID=24152630&HadPinnedHotel=true&regionId=553248635976386992&adults=2&guestRating=35&openPlayBack=true)

![Terrace/patio](https://images.trvl-media.com/lodging/20000000/19720000/19716300/19716268/66da1da6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/20000000/19720000/19716300/19716268/ba58a987.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/20000000/19720000/19716300/19716268/9adf18be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/20000000/19720000/19716300/19716268/70d04980.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Courtyard by Marriott Houston Intercontinental Airport

31.8 km from South Main

9.0/10

Wonderful

(1019)

CA $141

CA $165 total

includes taxes & fees

Nov 8 - Nov 9

[](https://www.expedia.ca/Hotel-Search?startDate=2025-11-08&endDate=2025-11-09&selected=19716268&PinnedHotelID=19716268&HadPinnedHotel=true&regionId=553248635976386992&adults=2&guestRating=35&openPlayBack=true)

![Lobby](https://images.trvl-media.com/lodging/1000000/870000/861200/861181/w3835h2555x4y0-996a6f84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/870000/861200/861181/3ebd956b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/870000/861200/861181/f2c86566.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/870000/861200/861181/w3840h2557x0y0-0cc1eb32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Garden Inn Houston/Bush Intercontinental Airport

31 km from South Main

8.2/10

Very good

(1029)

CA $113

CA $133 total

includes taxes & fees

Nov 21 - Nov 22

[](https://www.expedia.ca/Hotel-Search?startDate=2025-11-21&endDate=2025-11-22&selected=861181&PinnedHotelID=861181&HadPinnedHotel=true&regionId=553248635976386992&adults=2&guestRating=35&openPlayBack=true)

![Reception](https://images.trvl-media.com/lodging/1000000/10000/6300/6298/90f3bec7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/6300/6298/9b1acb52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/6300/6298/897c7071.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/6300/6298/1f62008d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Heritage Place Houston Brookhollow

15.3 km from South Main

8.4/10

Very good

(495)

CA $85

CA $99 total

includes taxes & fees

Nov 19 - Nov 20

[](https://www.expedia.ca/Hotel-Search?startDate=2025-11-19&endDate=2025-11-20&selected=6298&PinnedHotelID=6298&HadPinnedHotel=true&regionId=553248635976386992&adults=2&guestRating=35&openPlayBack=true)

![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/1000000/90000/82600/82533/70d101be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/90000/82600/82533/bf2802df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/90000/82600/82533/5e613111.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/90000/82600/82533/27dfc621.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sonesta Simply Suites Houston – NASA Clear Lake

31.7 km from South Main

8.2/10

Very good

(1021)

CA $79

CA $93 total

includes taxes & fees

Nov 19 - Nov 20

[](https://www.expedia.ca/Hotel-Search?startDate=2025-11-19&endDate=2025-11-20&selected=82533&PinnedHotelID=82533&HadPinnedHotel=true&regionId=553248635976386992&adults=2&guestRating=35&openPlayBack=true)

[See more properties](https://www.expedia.ca/Hotel-Search?startDate=2025-11-14&endDate=2025-11-15&regionId=553248635976386992&adults=2&sort=RECOMMENDED&guestRating=35&openPlayBack=true)

## Where to stay in South Main

Find the best South Main areas and neighborhoods for the activities you enjoy most.

-   Downtown Houston
-   The Galleria
-   Texas Medical Center
-   Montrose
-   Northside

![Discovery Green which includes city views, a square or plaza and a skyscraper](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/23000/23540-Discovery-Green.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Discovery Green showing a park, a skyscraper and street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/34000/34453-Discovery-Green.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/507000/507468-downtown-houston.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/507000/507497-downtown-houston.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Discovery Green showing a statue or sculpture, a high-rise building and modern architecture](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/34000/34451-Discovery-Green.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=800037)

![Downtown Houston map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:s%7CrtDz%7BbeQiQ_%40eEcBgCkDuQ%7D_%40m%5EeQ%7EMi%5DoAePiLi%60%40m%40%7DTlCsl%40pNj%5CxWzUxS%60Bv%7CAhmAcg%40ncAuI%60DmZx%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=WgKNf3zxiTWREKGzy8I1t3uy5Hs=)

### Downtown Houston

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=800037)

![](https://mediaim.expedia.com/destination/1/733d46a93b53c864b5c00945f6416b51.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/1/d7dc12b9d267be169566d38db8ea7eac.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/7/01538c9f6eb646ea96e3df2059618b27.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/7/374a9a687602bd093583e97522a04bc6.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/9/aadfd687906d99829a520409ec046d47.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=501263)

![The Galleria map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7DxptDn%7DteQ_AcXqKr%40mHsB%7BXT%5DgYeZY%3F%7D%60%40jGi%40rA_HxCyFTuIpzAsBbBt%7D%40fw%40%60NdA%7Ce%40szAdB&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=5e77b0krOIeDwBK5_jkO84swezY=)

### The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Gerald D. Hines Waterwall Park.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=501263)

![](https://mediaim.expedia.com/destination/1/f4655cac96c82fca6c00f4ab3162178c.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/7/29187be13ac57fa24b0f672247c7afbc.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/7/52a59f2a0bfb2cf153bbc44f917f7275.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=6143504)

![Texas Medical Center map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:wbftD%7C%60keQyBu%40u%5DkXgZySqC%7EG%7DEnG%7DQrDyAw%60%40aa%40gYrCsKe%5BcW%7CM_UbGi%40%60LmLjQmE%5DmPvB%60%40vEoQhGyJnDgKjKlC%7DDbTqAUq%40lDrYtHbGdd%40nKsDlOe%40bW%60Oj%40d_%40%7BFd%40%3FdRmCpA%3FdAtC%7CDL%60_%40eF%3F%7B%40uFiDf%40AqAwBB%7BC%60Ae%40yCm%40OlBhOjId%60%40hAnC&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=-txg4h32BKxrIPBjQzTWKWRnz0I=)

### Texas Medical Center

Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=6143504)

![Menil Collection which includes interior views and art](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/23000/23619-Menil-Collection.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Menil Collection featuring interior views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/23000/23623-Menil-Collection.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Menil Collection showing interior views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/34000/34667-Menil-Collection.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Menil Collection featuring a garden](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/34000/34665-Menil-Collection.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/34000/34668-Menil-Collection.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=3000663145)

![Montrose map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:wiptDf%7CieQmBWy%7E%40R%7BAe%40qByG_CiCwQJiG%60%40X%7BBoAyGIeOwDsLe%40qDh%40uJ%7D%40sCSsDuCkJJyE%60AsGLaMnD%7DQBcLreAQGwItTKI_MvFAb%40a%40rNdApW%40nf%40l%5D%60BlBnFpdBf%40tTElUyoA%5C&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=FA9GMjOoslAVD7SwHDyMnspJbfU=)

### Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Houston Center for Photography while you're exploring the area.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=3000663145)

![](https://mediaim.expedia.com/destination/7/b249298face16fd5795cf74face8ed8d.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/7/7f180593ef78263134eb6f20e72fd6c3.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=553248635976387525)

![Northside map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:muquD%60e%7DeQS_uAwHCiF%7B%40eOkIi%40dAf%40oAhOnIfFz%40%7CHB%3Ff%40bqCs%40%3FqP%7CBA%3FgKkUFzCeb%40%60u%40%5BJlx%40tq%40%3FV%7BOrD_GhAsKxG%7BG%40aB%7DS%7CJwIgSn%5Bo%5Bc%60A%5EUanAmEqAsFwCcGr%40yITqExA%7BBMQkXpJAEkNiFDBaS%7EFaJ%7E%5Eq%5EoBszBgmA%5Ci%40myAgFF%3FeAiDFIoIsYFYcEaBmFuoAj%40eaAgCNf%60%40__AZZzv%40hGx%5Ez%40VJvAk%40l%40HnI%7DQD%40pkA%60%40rMqSJ%3FfEoB%40AgEsKB_%40k%7EAaEyFoC%3F_EkEcEuCtCAY_SmKBBbIqHDgDgDu%40mBGcFnPF%60J_%40CwLqy%40ZD%7Ef%40aG%40%40tMw%40bJEvGcq%40RJyg%40aLC%3FsBzBcFjHC%3Fs%5DkFnBwCxBiS%60W_D%3FW%7Bl%40zd%40mG%3FmGlLM%3FbD%7ENoBhi%40i%40bVaArH%7D%40o%40geB%7DXJMif%40fJGUux%40tdCy_%40vB%7ERj%40dRlOEDtK%7BOHC%7EKnBA%40%7CK%60bBi%40x%40dbBpIVltA%7D%40jIn%40nmCg%40i%40mgCOgAiM%7EG%5D%7BqAmFC%3FrCcHA%40nC%7D%5E%40CaQaVT%40%5EsNaMoARg%40wGj%5DwEl%60A%7DOOe%5D%7EHAHzZdScDvJVw%40csCiLcAcDfBcDf%40Iyh%40jVOHwZvZvNMqfBayCg%7D%40Sc%60%40kq%40E%40u%40%7DF%40AqEyP%3FKkWkZNI%7DZee%40Zl%40eF%7CBC%40%60C%60D%3FGiVxpAk%40NpO%60KIPbn%40ve%40O%5Bqz%40jd%40OEya%40vLEAmHts%40W%5Da_B%60lCrjCjZ_CtfB%7CAXsObgDc%40JxYj%5E%5EpaAzrCvuCXjEtQfl%40vZqG%60R%7DN%7EP%7C%40%7CUhHdSmSrCuBzWvDzNeEbf%40uYnGwRwe%40cCd_ArSfu%40s%60%40%7E%60%40u_%40%7EZiKhk%40dQtm%40uAxaB_JDIpSkK%7CJfFfLC%7EHsK%7DBku%40dDj%40fJaLmAApX%7CLxDcItPeIlFuF%7CNkc%40fN%7BOpNoA%7E%5BsLdPiPjb%40ut%40nYq%40ti%40gNr%5EbAlaAsfC%7EwCkDKw%40mJtCcGavBu%40aZuJoEBn%40%7C%7EAyq%40%5CgCp%5C%7B%60B%3F%5DcfAgwCbuA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=SL4qRZsnUhbIVHkfA1was5maM1w=)

### Northside

While you're in Northside, take in top sights like The Heights Theater or Greenspoint Mall, and hop on the metro to see more the city at Northline Transit Center/HCC Station or Melbourne/North Lindale Station.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976387525)

## Top South Main Hotel Reviews

![La Quinta Inn & Suites by Wyndham Houston Bush IAH South](//images.trvl-media.com/lodging/1000000/170000/165600/165562/0afb5a51_y.jpg)

### La Quinta Inn & Suites by Wyndham Houston Bush IAH South

10/10 Excellent

"Room was clean staff was great "

[](https://expedia.ca/Houston-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Houston-Bush-IAH-South.h165562.Hotel-Information)

![Hilton Americas-Houston](//images.trvl-media.com/lodging/1000000/980000/976200/976144/09dd0b59_y.jpg)

### Hilton Americas-Houston

10/10 Excellent

"Great hotel in an easily accessible part of downtown. "

[](https://expedia.ca/Houston-Hotels-Hilton-Americas-Houston.h976144.Hotel-Information)

![DoubleTree by Hilton Hotel & Suites Houston by the Galleria](//images.trvl-media.com/lodging/1000000/30000/20200/20116/555244ce_y.jpg)

### DoubleTree by Hilton Hotel & Suites Houston by the Galleria

10/10 Excellent

"The restaurant food was amazing. Had dinner at the bar and it was a great choice. The staff was nice and valet was pretty quick "

[](https://expedia.ca/Houston-Hotels-DoubleTree-By-Hilton-Hotel-Suites-Houston-By-The-Galleria.h20116.Hotel-Information)

![The Whitehall Houston](//images.trvl-media.com/lodging/1000000/700000/693700/693655/f1d85056_y.jpg)

### The Whitehall Houston

10/10 Excellent

"Good place, clean, like outside bar and pool. Thanks "

[](https://expedia.ca/Houston-Hotels-The-Whitehall-Houston.h693655.Hotel-Information)

![The Royal Sonesta Houston Galleria](//images.trvl-media.com/lodging/1000000/880000/878700/878652/9874e960_y.jpg)

### The Royal Sonesta Houston Galleria

10/10 Excellent

"Decent hotel but rhe breakfast variety and toilet cleanliness could be better."

[](https://expedia.ca/Houston-Hotels-Royal-Sonesta-Houston-Galleria.h878652.Hotel-Information)

![Hilton Houston Plaza/Medical Center](//images.trvl-media.com/lodging/1000000/30000/25200/25188/294f3d50_y.jpg)

### Hilton Houston Plaza/Medical Center

10/10 Excellent

"I didn't eat at hotel . Had a great stay . Comfortable and clean"

[](https://expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information)

![Blossom Hotel Houston, Curio Collection by Hilton](//images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/dc9d050c_y.jpg)

### Blossom Hotel Houston, Curio Collection by Hilton

10/10 Excellent

"10/10"

[](https://expedia.ca/Houston-Hotels-Blossom-Hotel-Houston.h58985846.Hotel-Information)

![Crowne Plaza Houston Med Ctr-Galleria Area by IHG](//images.trvl-media.com/lodging/1000000/30000/28100/28060/38218191_y.jpg)

### Crowne Plaza Houston Med Ctr-Galleria Area by IHG

10/10 Excellent

"Good "

[](https://expedia.ca/Houston-Hotels-Crowne-Plaza-Houston-River-Oaks.h28060.Hotel-Information)

![Cambria Hotel Houston Downtown Convention Center](//images.trvl-media.com/lodging/36000000/35560000/35559700/35559679/82e8dff0_y.jpg)

### Cambria Hotel Houston Downtown Convention Center

10/10 Excellent

"Very nice, updated rooms in a historical building. All staff were friendly and helpful."

[](https://expedia.ca/Houston-Hotels-Cambria-Hotel-Houston-Downtown-Convention-Center.h35559679.Hotel-Information)

## Frequently asked questions

### What are the best hotels in South Main that travellers recommend?

> [Wyndham Houston near NRG Park/Medical Center](https://www.expedia.ca/Houston-Hotels-Wyndham-Houston-Near-NRG-ParkMedical-Center.h21297.Hotel-Information) is a solid choice for travellers seeking comfort and convenience, earning a customer review rating of 7.2. This hotel features an inviting outdoor pool, superb for unwinding after a day of adventure, along with kitchenettes in the rooms—ideal for families wanting to prepare snacks or meals. The combination of free WiFi and a 24-hour business centre makes it suitable for both leisure and business travellers, ensuring a straightforward stay.
> 
>   
> 
> For families, [Wingate Houston near NRG Park/Medical Center](https://www.expedia.ca/Houston-Hotels-Wingate-By-Wyndham-Houston-Reliant-Medical-Center.h66022895.Hotel-Information) is another great option. With a complimentary continental breakfast to fuel your adventures and a refreshing outdoor pool, it caters superbly to parents and kids alike. The accessible fitness centre allows for some family fun, while the hotel's pet-friendly policies make it a fantastic choice for those traveling with furry companions. With a focus on convenience and value, this hotel provides excellent amenities while keeping everyone comfortable.

### What are the best family hotels in South Main?

> When it comes to family-friendly hotels in South Main, the [Comfort Suites near Texas Medical Center - NRG Stadium](https://www.expedia.ca/Houston-Hotels-Comfort-Suites-Near-Texas-Medical-Center-NRG-Stadium.h904192.Hotel-Information) shines brightly with a solid traveller review rating of 8.6. This hotel offers daily housekeeping to ensure your family's stay is comfortable and straightforward.
> 
>   
> 
> Another excellent option is the [Candlewood Suites Houston Medical Center by IHG](https://www.expedia.ca/Houston-Hotels-Candlewood-Suites-Houston-Medical-Center.h2227000.Hotel-Information), which boasts a family-friendly atmosphere with its free cribs, connecting rooms, and a sofa bed, making it great for families needing extra space. Guests appreciate the convenience of in-room kitchen amenities like a microwave and dishwasher, allowing for easy meal prep during your stay. It has a review score of 7.6, reflecting its appeal to families on the go.
> 
>   
> 
> For those seeking a place with a pool, the [Quality Inn & Suites NRG Park - Medical Center](https://www.expedia.ca/Houston-Hotels-Quality-Inn-Suites-NRG-Park-Medical-Center.h17531.Hotel-Information) is a great choice. With its inviting pool area, free meals for children, and options for rollaway beds at no extra charge, families can enjoy a splash-filled vacation while also benefiting from daily housekeeping and snack options.
> 
>   
> 
> Lastly, the [Wyndham Houston near NRG Park/Medical Center](https://www.expedia.ca/Houston-Hotels-Wyndham-Houston-Near-NRG-ParkMedical-Center.h21297.Hotel-Information) features child-friendly window designs and connecting rooms, catering specifically to families' needs. The presence of kitchenettes adds to the convenience, allowing families to prepare snacks or meals together. This property has a traveller rating of 7.2, making it a reliable choice for family stays.
> 
>   
> 
> These hotels exemplify quality and convenience, ensuring that your family's adventure in South Main is both enjoyable and comfortable.

### What hotels in South Main offer free breakfast?

> [Comfort Suites near Texas Medical Center - NRG Stadium](https://www.expedia.ca/Houston-Hotels-Comfort-Suites-Near-Texas-Medical-Center-NRG-Stadium.h904192.Hotel-Information) is a fantastic option for travellers seeking comfort and convenience in South Main. With a traveller review rating of 8.6, this hotel offers a delightful free full breakfast to start your day right. Families will appreciate the seasonal outdoor pool, superb for a refreshing dip after a day of exploring. Additionally, the property features complimentary WiFi and self-parking, making it easy to stay connected and save on travel expenses.
> 
>   
> 
> Another great choice is [Quality Inn & Suites NRG Park - Medical Center](https://www.expedia.ca/Houston-Hotels-Quality-Inn-Suites-NRG-Park-Medical-Center.h17531.Hotel-Information), which also provides a free breakfast, including options for those on the go. This family-friendly hotel offers spacious suites with balconies and patios, allowing families to unwind outdoors. The outdoor pool invites guests to relax and enjoy the Texas sunshine, while the complimentary area shuttle makes it simple to explore the attractions nearby.
> 
>   
> 
> For those traveling without children, the [Wingate Houston near NRG Park/Medical Center](https://www.expedia.ca/Houston-Hotels-Wingate-By-Wyndham-Houston-Reliant-Medical-Center.h66022895.Hotel-Information) presents a delightful blend of comfort and accessibility. With an outdoor pool and fitness centre, it caters to adults looking for a rejuvenating getaway. The hotel's continental breakfast is another perk that guarantees a satisfying start to your morning adventures.

### What are the best budget hotels in South Main?

> [Comfort Suites near Texas Medical Center - NRG Stadium](https://www.expedia.ca/Houston-Hotels-Comfort-Suites-Near-Texas-Medical-Center-NRG-Stadium.h904192.Hotel-Information) is a fantastic budget-friendly option for travellers seeking convenience and quality in South Main. With an excellent review score of 8.6, this hotel offers a range of family-friendly amenities, including a seasonal outdoor pool, free breakfast, and complimentary WiFi. Families will appreciate the spacious rooms and the convenience of free self-parking, making it easy to explore the area together.
> 
>   
> 
> For another appealing choice, [Candlewood Suites Houston Medical Center by IHG](https://www.expedia.ca/Houston-Hotels-Candlewood-Suites-Houston-Medical-Center.h2227000.Hotel-Information) stands out with a review score of 7.6. This property is superb for families, as it features kitchenettes in the rooms, allowing for meal preparation and snacks on the go. Kids can also enjoy the complimentary cribs and sofa beds, making it a comfortable stay for everyone. Additionally, the hotel offers a free area shuttle, which is great for exploring local attractions without the hassle of driving.
> 
>   
> 
> If you're traveling with your partner or friends, the [Wyndham Houston near NRG Park/Medical Center](https://www.expedia.ca/Houston-Hotels-Wyndham-Houston-Near-NRG-ParkMedical-Center.h21297.Hotel-Information) offers a more relaxed atmosphere with a lower review score of 7.2. This hotel features outdoor pool access and convenient amenities, including a kitchenette in some rooms, which can appeal to those looking for a home-like experience while away.
> 
>   
> 
> No matter your travel group, these options in South Main cater to various needs while ensuring a comfortable and enjoyable stay.

### Can I cancel my hotel reservation on Expedia?

> You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in South Main.

### How can I save on a South Main hotel booking with Expedia?

> Members always get our best prices. Find our best South Main hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.

### How much is the nightly rate at a South Main hotel?

> Hotel prices in South Main often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

## Explore a world of travel with Expedia

-   Lodging
-   Flights
-   Packages
-   Cars
-   Other
-   More ways to book

-   [Casino Hotels in Astrodome](https://www.expedia.ca/Astrodome-Houston-Hotels-Casino-Hotel.0-n553248635976007975-0-tCasinoHotel.Travel-Guide-Filter-Hotels)
-   [Cheap Hotels in Astrodome](https://www.expedia.ca/Astrodome-Houston-Hotels-Cheap-Hotels.0-n553248635976007975-0-tCheapHotels.Travel-Guide-Filter-Hotels)
-   [Luxury Hotels in Astrodome](https://www.expedia.ca/Astrodome-Houston-Hotels-Luxury-Hotel.0-n553248635976007975-0-tLuxuryHotel.Travel-Guide-Filter-Hotels)
-   [Spa Hotels in Astrodome](https://www.expedia.ca/Astrodome-Houston-Hotels-Spa-Hotel.0-n553248635976007975-0-tSpaHotel.Travel-Guide-Filter-Hotels)
-   [Astrodome Hotels](https://www.expedia.ca/Astrodome-Houston-Hotels.0-n553248635976007975-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Aveva Stadium](https://www.expedia.ca/Aveva-Stadium-Hotels.0-l676706154760683520-0.Travel-Guide-Filter-Hotels)
-   [Bellaire Hotels](https://www.expedia.ca/Bellaire-Hotels.d78408.Travel-Guide-Hotels)
-   [Cheap Hotels in Braeswood Place](https://www.expedia.ca/Braeswood-Place-Houston-Hotels-Cheap-Hotels.0-n553248635976387047-0-tCheapHotels.Travel-Guide-Filter-Hotels)
-   [Hotels & Resorts for Couples in Braeswood Place](https://www.expedia.ca/Braeswood-Place-Houston-Hotels-Couples-Resorts-Hotels.0-n553248635976387047-0-tCouplesResortsHotels.Travel-Guide-Filter-Hotels)
-   [Hotels with a Pool in Braeswood Place](https://www.expedia.ca/Braeswood-Place-Houston-Hotels-Hotel-With-Pool.0-n553248635976387047-0-tHotelwithPool.Travel-Guide-Filter-Hotels)
-   [Braeswood Place Hotels](https://www.expedia.ca/Braeswood-Place-Houston-Hotels.0-n553248635976387047-0.Travel-Guide-Filter-Hotels)
-   [B&B in Dryden/TMC Station](https://www.expedia.ca/DrydenTMC-Station-Bed-And-Breakfast.d6211670-aaBedAndBreakfast.Travel-Guide-Accommodation)
-   [Hotels near Dryden/TMC Station](https://www.expedia.ca/DrydenTMC-Station-Hotels.d6211670.Travel-Guide-Hotels)
-   [Inns in Dryden/TMC Station](https://www.expedia.ca/DrydenTMC-Station-Inns.d6211670-aaInns.Travel-Guide-Accommodation)
-   [Motels in Dryden/TMC Station](https://www.expedia.ca/DrydenTMC-Station-Motels.d6211670-aaMotels.Travel-Guide-Accommodation)
-   [Resorts in Dryden/TMC Station](https://www.expedia.ca/DrydenTMC-Station-Resort-Hotels.d6211670-aaResortHotels.Travel-Guide-Accommodation)
-   [Hotels near Fannin South Station](https://www.expedia.ca/Fannin-South-Station-Hotels.d6211683.Travel-Guide-Hotels)
-   [Houston Hotels](https://www.expedia.ca/Houston-Hotels.d178265.Travel-Guide-Hotels)
-   [Hotels near Houston Methodist Hospital](https://www.expedia.ca/Houston-Methodist-Hospital-Hotels.0-l553248635389802729-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Houston Zoo](https://www.expedia.ca/Houston-Zoo-Hotels.0-l6082223-0.Travel-Guide-Filter-Hotels)
-   [Hotels near MD Anderson Cancer Center](https://www.expedia.ca/MD-Anderson-Cancer-Center-Hotels.0-l6248539-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Main Street Theater - Rice Village](https://www.expedia.ca/Main-Street-Theater-Rice-Village-Hotels.0-l553248621561866623-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Memorial Hermann Hospital/Houston Zoo Station](https://www.expedia.ca/Memorial-Hermann-HospitalHouston-Zoo-Station-Hotels.d6211668.Travel-Guide-Hotels)
-   [Hotels near Meyerland Plaza Shopping Center](https://www.expedia.ca/Meyerland-Plaza-Shopping-Center-Hotels.0-l6237481-0.Travel-Guide-Filter-Hotels)
-   [Hotels near NRG Arena](https://www.expedia.ca/NRG-Arena-Hotels.0-l553248635975094722-0.Travel-Guide-Filter-Hotels)
-   [Hotels near NRG Astrodome](https://www.expedia.ca/NRG-Astrodome-Hotels.0-l803579369198804992-0.Travel-Guide-Filter-Hotels)
-   [Hotels near NRG Center](https://www.expedia.ca/NRG-Center-Hotels.0-l553248635389801959-0.Travel-Guide-Filter-Hotels)
-   [Hotels near NRG Park](https://www.expedia.ca/NRG-Park-Hotels.0-l6353215-0.Travel-Guide-Filter-Hotels)
-   [Hotels near NRG Stadium](https://www.expedia.ca/NRG-Stadium-Hotels.0-l553248635929331916-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Rice Stadium](https://www.expedia.ca/Rice-Stadium-Hotels.0-l6091875-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Rice University](https://www.expedia.ca/Rice-University-Hotels.0-l501268-0.Travel-Guide-Filter-Hotels)
-   [Luxury Hotels in Rice Village](https://www.expedia.ca/Rice-Village-Houston-Hotels-Luxury-Hotel.0-n869686528136192000-0-tLuxuryHotel.Travel-Guide-Filter-Hotels)
-   [Rice Village Hotels](https://www.expedia.ca/Rice-Village-Houston-Hotels.0-n869686528136192000-0.Travel-Guide-Filter-Hotels)
-   [Budget Host Hotels in Southgate](https://www.expedia.ca/Southgate-Houston-Hotels-Budget-Host.0-n553248635976470716-0--bBudgetHost.Travel-Guide-Filter-Hotels)
-   [Southgate Hotels](https://www.expedia.ca/Southgate-Houston-Hotels.0-n553248635976470716-0.Travel-Guide-Filter-Hotels)
-   [Hotels with a Pool in Southside Place](https://www.expedia.ca/Southside-Place-Houston-Hotels-Hotel-With-Pool.0-n160529-0-tHotelwithPool.Travel-Guide-Filter-Hotels)
-   [Southside Place Hotels](https://www.expedia.ca/Southside-Place-Houston-Hotels.0-n160529-0.Travel-Guide-Filter-Hotels)
-   [Apartments in Southwest Houston](https://www.expedia.ca/Southwest-Houston-Apartments.d6189441-aaApartments.Travel-Guide-Accommodation)
-   [Condo Rentals in Southwest Houston](https://www.expedia.ca/Southwest-Houston-Condos.d6189441-aaCondos.Travel-Guide-Accommodation)
-   [Cottages in Southwest Houston](https://www.expedia.ca/Southwest-Houston-Cottages.d6189441-aaCottages.Travel-Guide-Accommodation)
-   [Beach Hotel Hotels in Southwest Houston](https://www.expedia.ca/Southwest-Houston-Hotels-Beach-Hotel.0-0-d6189441-tBeachHotel.Travel-Guide-Filter-Hotels)
-   [Casino Hotels in Southwest Houston](https://www.expedia.ca/Southwest-Houston-Hotels-Casino-Hotel.0-0-d6189441-tCasinoHotel.Travel-Guide-Filter-Hotels)
-   [Hilton Hotels in Southwest Houston](https://www.expedia.ca/Southwest-Houston-Hotels-Hilton-Hotels.0-0-d6189441--bHiltonHotels.Travel-Guide-Filter-Hotels)
-   [Southwest Houston Hotels](https://www.expedia.ca/Southwest-Houston-Hotels.d6189441.Travel-Guide-Hotels)
-   [Aparthotels in Stadium Park/Astrodome Station](https://www.expedia.ca/Stadium-ParkAstrodome-Station-Apart-Hotels.d6211680-aaApartHotels.Travel-Guide-Accommodation)
-   [Hostels in Stadium Park/Astrodome Station](https://www.expedia.ca/Stadium-ParkAstrodome-Station-Hostels.d6211680-aaHostels.Travel-Guide-Accommodation)
-   [Hotels near Stadium Park/Astrodome Station](https://www.expedia.ca/Stadium-ParkAstrodome-Station-Hotels.d6211680.Travel-Guide-Hotels)
-   [Farmstay in TMC Transit Center](https://www.expedia.ca/TMC-Transit-Center-Agritourism.d6211673-aaAgritourism.Travel-Guide-Accommodation)
-   [Hotels near Texas Children's Hospital](https://www.expedia.ca/Texas-Childrens-Hospital-Hotels.0-l553248635389801905-0.Travel-Guide-Filter-Hotels)
-   [Cheap Hotels in Texas Medical Center](https://www.expedia.ca/Texas-Medical-Center-Houston-Hotels-Cheap-Hotels.0-n6143504-0-tCheapHotels.Travel-Guide-Filter-Hotels)
-   [Family Hotels in Texas Medical Center](https://www.expedia.ca/Texas-Medical-Center-Houston-Hotels-Family-Hotel.0-n6143504-0-tFamilyHotel.Travel-Guide-Filter-Hotels)
-   [Hotels with a Pool in Texas Medical Center](https://www.expedia.ca/Texas-Medical-Center-Houston-Hotels-Hotel-With-Pool.0-n6143504-0-tHotelwithPool.Travel-Guide-Filter-Hotels)
-   [Hotels with Free Airport Shuttle in Texas Medical Center](https://www.expedia.ca/Texas-Medical-Center-Houston-Hotels-Hotels-With-Free-Airport-Shuttle.0-n6143504-0-tHotelswithFreeAirportShuttle.Travel-Guide-Filter-Hotels)
-   [Hotels with Free Breakfast in Texas Medical Center](https://www.expedia.ca/Texas-Medical-Center-Houston-Hotels-Hotels-With-Free-Breakfast.0-n6143504-0-tHotelswithFreeBreakfast.Travel-Guide-Filter-Hotels)
-   [Hotels with Kitchenettes in Texas Medical Center](https://www.expedia.ca/Texas-Medical-Center-Houston-Hotels-Hotels-With-Kitchenettes.0-n6143504-0-tHotelswithKitchenettes.Travel-Guide-Filter-Hotels)
-   [Hyatt Hotels in Texas Medical Center](https://www.expedia.ca/Texas-Medical-Center-Houston-Hotels-Hyatt-Hotels.0-n6143504-0--bHyattHotels.Travel-Guide-Filter-Hotels)
-   [Luxury Hotels in Texas Medical Center](https://www.expedia.ca/Texas-Medical-Center-Houston-Hotels-Luxury-Hotel.0-n6143504-0-tLuxuryHotel.Travel-Guide-Filter-Hotels)
-   [Mountain Hotels in Texas Medical Center](https://www.expedia.ca/Texas-Medical-Center-Houston-Hotels-Mountain-Hotels.0-n6143504-0-tMountainHotels.Travel-Guide-Filter-Hotels)
-   [Oceanfront Hotels in Texas Medical Center](https://www.expedia.ca/Texas-Medical-Center-Houston-Hotels-Oceanfront-Hotels.0-n6143504-0-tOceanfrontHotels.Travel-Guide-Filter-Hotels)
-   [Pet-Friendly Hotels in Texas Medical Center](https://www.expedia.ca/Texas-Medical-Center-Houston-Hotels-Pet-Friendly-Hotel.0-n6143504-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels)
-   [Shopping Hotels in Texas Medical Center](https://www.expedia.ca/Texas-Medical-Center-Houston-Hotels-Shopping-Hotel.0-n6143504-0-tShoppingHotel.Travel-Guide-Filter-Hotels)
-   [Waterpark Hotels in Texas Medical Center](https://www.expedia.ca/Texas-Medical-Center-Houston-Hotels-Waterpark-Hotels.0-n6143504-0-tWaterparkHotels.Travel-Guide-Filter-Hotels)
-   [Texas Medical Center Hotels](https://www.expedia.ca/Texas-Medical-Center-Houston-Hotels.0-n6143504-0.Travel-Guide-Filter-Hotels)
-   [University Place Hotels](https://www.expedia.ca/University-Place-Houston-Hotels.0-n553248635976386985-0.Travel-Guide-Filter-Hotels)
-   [West University Place Hotels](https://www.expedia.ca/West-University-Place-Houston-Hotels.0-n173399-0.Travel-Guide-Filter-Hotels)
-   [Willow Meadows/Willowbend Area Hotels](https://www.expedia.ca/Willow-MeadowsWillowbend-Area-Houston-Hotels.0-n553248635976384858-0.Travel-Guide-Filter-Hotels)

-   [Flights to Houston](https://www.expedia.ca/Cheap-Flights-To-Houston.d178265.Travel-Guide-Flights)
-   [Flights to Southwest Houston](https://www.expedia.ca/Cheap-Flights-To-Southwest-Houston.d6189441.Travel-Guide-Flights)
-   [Flights from Amsterdam to Southwest Houston](https://www.expedia.ca/lp/flights/178229/6189441/amsterdam-to-southwest-houston)
-   [Flights from Atlanta to Southwest Houston](https://www.expedia.ca/lp/flights/178232/6189441/atlanta-to-southwest-houston)
-   [Flights from Auckland to Southwest Houston](https://www.expedia.ca/lp/flights/178233/6189441/auckland-to-southwest-houston)
-   [Flights from Baltimore to Southwest Houston](https://www.expedia.ca/lp/flights/178235/6189441/baltimore-to-southwest-houston)
-   [Flights from Bogotá to Southwest Houston](https://www.expedia.ca/lp/flights/178238/6189441/bogota-to-southwest-houston)
-   [Flights from Calgary to Southwest Houston](https://www.expedia.ca/lp/flights/178245/6189441/calgary-to-southwest-houston)
-   [Flights from Chicago to Southwest Houston](https://www.expedia.ca/lp/flights/178248/6189441/chicago-to-southwest-houston)
-   [Flights from Dallas to Southwest Houston](https://www.expedia.ca/lp/flights/178253/6189441/dallas-to-southwest-houston)
-   [Flights from Detroit to Southwest Houston](https://www.expedia.ca/lp/flights/178255/6189441/detroit-to-southwest-houston)
-   [Flights from Raleigh to Southwest Houston](https://www.expedia.ca/lp/flights/178300/6189441/raleigh-to-southwest-houston)
-   [Flights from Seattle to Southwest Houston](https://www.expedia.ca/lp/flights/178307/6189441/seattle-to-southwest-houston)
-   [Flights from St. Louis to Southwest Houston](https://www.expedia.ca/lp/flights/178309/6189441/st-louis-to-southwest-houston)
-   [Flights from Richmond to Southwest Houston](https://www.expedia.ca/lp/flights/601761/6189441/richmond-to-southwest-houston)

-   [Visit Astrodome](https://www.expedia.ca/Houston-Astrodome.dx553248635976007975)
-   [Visit Southside Place](https://www.expedia.ca/Houston-Southside-Place.dx160529)
-   [Visit Texas Medical Center](https://www.expedia.ca/Houston-Texas-Medical-Center.dx6143504)
-   [Md Anderson Cancer Center](https://www.expedia.ca/MD-Anderson-Cancer-Center-Texas-Medical-Center.d6248539.Vacation-Attraction)
-   [Nrg Stadium](https://www.expedia.ca/NRG-Stadium-Astrodome.d553248635929331916.Vacation-Attraction)
-   [Visit Southwest Houston](https://www.expedia.ca/Southwest-Houston.dx6189441)

-   [Airport Van Rental Rental Cars in Southwest Houston](https://www.expedia.ca/Airport-Van-Rental-Car-Rentals-In-Southwest-Houston.d6189441-c1092.Car-Rental-Guide-Suppliers)
-   [Alamo Rent A Car Rental Cars in Southwest Houston](https://www.expedia.ca/Alamo-Rent-A-Car-Car-Rentals-In-Southwest-Houston.d6189441-c6.Car-Rental-Guide-Suppliers)
-   [Auto Rent Rental Cars in Southwest Houston](https://www.expedia.ca/Auto-Rent-Car-Rentals-In-Southwest-Houston.d6189441-c1006.Car-Rental-Guide-Suppliers)
-   [Budget Rental Cars in Southwest Houston](https://www.expedia.ca/Budget-Car-Rentals-In-Southwest-Houston.d6189441-c39.Car-Rental-Guide-Suppliers)
-   [Discount Quebec Rental Cars in Southwest Houston](https://www.expedia.ca/Discount-Quebec-Car-Rentals-In-Southwest-Houston.d6189441-c1137.Car-Rental-Guide-Suppliers)
-   [Global Rent a Car Rental Cars in Southwest Houston](https://www.expedia.ca/Global-Rent-A-Car-Car-Rentals-In-Southwest-Houston.d6189441-c1062.Car-Rental-Guide-Suppliers)
-   [Goldcar Key’n Go Rental Cars in Southwest Houston](https://www.expedia.ca/Goldcar-Keyn-Go-Car-Rentals-In-Southwest-Houston.d6189441-c1044.Car-Rental-Guide-Suppliers)
-   [Hertz Rental Cars in Southwest Houston](https://www.expedia.ca/Hertz-Car-Rentals-In-Southwest-Houston.d6189441-c40.Car-Rental-Guide-Suppliers)
-   [Localiza Rental Cars in Southwest Houston](https://www.expedia.ca/Localiza-Car-Rentals-In-Southwest-Houston.d6189441-c1063.Car-Rental-Guide-Suppliers)
-   [Locauto Rental Cars in Southwest Houston](https://www.expedia.ca/Locauto-Car-Rentals-In-Southwest-Houston.d6189441-c1140.Car-Rental-Guide-Suppliers)
-   [Nextcar Rental Cars in Southwest Houston](https://www.expedia.ca/Nextcar-Car-Rentals-In-Southwest-Houston.d6189441-c1061.Car-Rental-Guide-Suppliers)
-   [Rent A Wreck Rental Cars in Southwest Houston](https://www.expedia.ca/Rent-A-Wreck-Car-Rentals-In-Southwest-Houston.d6189441-c33.Car-Rental-Guide-Suppliers)

-   [Things to do in Southwest Houston](https://www.expedia.ca/Things-To-Do-In-Southwest-Houston.d6189441.Travel-Guide-Activities)

-   [Book Hotels in South Main on Expedia.com](https://www.expedia.com/South-Main-Houston-Hotels.0-n553248635976386992-0.Travel-Guide-Filter-Hotels)