Title: 10 Best Hotels in South Main, Houston for 2026 | Expedia.ca [Vacation Rentals in Houston](https://expedia.ca/Houston-Vacation-Rentals.d178265.Travel-Guide-VacationRentals)[Flights to Houston](https://expedia.ca/Cheap-Flights-To-Houston.d178265.Travel-Guide-Flights)[Things to do in Houston](https://expedia.ca/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities)[South Main Car Rentals](https://expedia.ca/Car-Rentals-In-South-Main.d553248635976386992.Car-Rental-Guide)[South Main Vacations](https://expedia.ca/South-Main.d553248635976386992.Destination-Travel-Guides) ![](https://images.trvl-media.com/place/1503/2eeb9f80-ebf6-42ad-9574-1d77038420db.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Hotels in South Main, Houston - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 24 - Dec 25](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2025-12-24&endDate=2025-12-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 25 - Dec 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2025-12-25&endDate=2025-12-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for South Main hotels ![Individually decorated, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/910000/904200/904192/3aca26b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/910000/904200/904192/d9fe05fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/910000/904200/904192/ba5d9607.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/904200/904192/28e82f54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Houston near Medical Center- NRG Stadium [](https://www.expedia.ca/Houston-Hotels-Comfort-Suites-Near-Texas-Medical-Center-NRG-Stadium.h904192.Hotel-Information) South Main 8.6/10 Excellent (1002) "Clean room, helpful staff and good location to hospital." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) George CA $108 CA $126 total includes taxes & fees Dec 25 - Dec 26 [](https://www.expedia.ca/Houston-Hotels-Comfort-Suites-Near-Texas-Medical-Center-NRG-Stadium.h904192.Hotel-Information) ![Premium bedding, pillowtop beds, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/99a71929.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/w2558h1440x0y0-44773629.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 10:00 AM to 6:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/e04a9b51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/63833027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Houston near NRG Park/Medical Center [](https://www.expedia.ca/Houston-Hotels-Wyndham-Houston-Near-NRG-ParkMedical-Center.h21297.Hotel-Information) South Main 7.2/10 Good (1198) "Love this place. Been staying here for many years. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Reynaldo CA $122 CA $143 total includes taxes & fees Dec 25 - Dec 26 [](https://www.expedia.ca/Houston-Hotels-Wyndham-Houston-Near-NRG-ParkMedical-Center.h21297.Hotel-Information) ![Hypo-allergenic bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/20000/17600/17531/2ae57d48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/17600/17531/23f0ff28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/17600/17531/258cd217.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/20000/17600/17531/78978179.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites NRG Park - Medical Center [](https://www.expedia.ca/Houston-Hotels-Quality-Inn-Suites-NRG-Park-Medical-Center.h17531.Hotel-Information) South Main 6.6/10 (1001) "Clean rooms, quiet property. We will be back again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Javier CA $76 CA $90 total includes taxes & fees Jan 11 - Jan 12, 2026 [](https://www.expedia.ca/Houston-Hotels-Quality-Inn-Suites-NRG-Park-Medical-Center.h17531.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/eca4a935.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/6b2e094a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/bf35ca47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/dec1e7ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wingate Houston near NRG Park/Medical Center [](https://www.expedia.ca/Houston-Hotels-Wingate-By-Wyndham-Houston-Reliant-Medical-Center.h66022895.Hotel-Information) South Main 6.6/10 (991) "Great staff, excellent service and convenient to the area we were wanting to be. Room was clean and bed was very comfortable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roy CA $94 CA $110 total includes taxes & fees Dec 25 - Dec 26 [](https://www.expedia.ca/Houston-Hotels-Wingate-By-Wyndham-Houston-Reliant-Medical-Center.h66022895.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/168bdeac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/14da1a00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/2693cb6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/b0f701b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Candlewood Suites Houston Medical Center by IHG [](https://www.expedia.ca/Houston-Hotels-Candlewood-Suites-Houston-Medical-Center.h2227000.Hotel-Information) South Main 7.4/10 Good (824) "This is a safe, friendly hotel close to MDA Cancer Center" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Myra CA $96 CA $112 total includes taxes & fees Dec 29 - Dec 30 [](https://www.expedia.ca/Houston-Hotels-Candlewood-Suites-Houston-Medical-Center.h2227000.Hotel-Information) ![Breakfast, lunch, dinner served; Regional cuisine ](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/d170df91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/aa7fafd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast (USD 17 per person)](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/4c12ff6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/76e7278c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Club Quarters Hotel Downtown, Houston [](https://www.expedia.ca/Houston-Hotels-Club-Quarters-Hotel-In-Houston.h1156923.Hotel-Information) Houston Central Business District, 10.9 km from South Main 8.4/10 Very good (3962) "Rooms were great and the staff was absolutely amazing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elmer CA $98 CA $115 total includes taxes & fees Dec 26 - Dec 27 [](https://www.expedia.ca/Houston-Hotels-Club-Quarters-Hotel-In-Houston.h1156923.Hotel-Information) ![Staircase](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/5506d9bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/8e6106b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/b032cc4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/8822a961.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Royal Sonesta Houston Galleria [](https://www.expedia.ca/Houston-Hotels-Royal-Sonesta-Houston-Galleria.h878652.Hotel-Information) The Galleria, 8.8 km from South Main 8.4/10 Very good (1484) "Staff members very nice, hotel as a whole very clean " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lester CA $138 CA $162 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Houston-Hotels-Royal-Sonesta-Houston-Galleria.h878652.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/28000000/27300000/27293900/27293821/88ce8c5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/28000000/27300000/27293900/27293821/522c66f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/28000000/27300000/27293900/27293821/a403ab12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27300000/27293900/27293821/2b2d8506.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Houston Webster NASA [](https://www.expedia.ca/Houston-Hotels-Tru-By-Hilton-Houston-Webster-NASA.h27293821.Hotel-Information) 30.8 km from South Main 9.0/10 Wonderful (1000) "The staff was super nice and the location worked great for us! " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Valeria CA $105 CA $123 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Houston-Hotels-Tru-By-Hilton-Houston-Webster-NASA.h27293821.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/20000000/19720000/19716300/19716268/66da1da6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/20000000/19720000/19716300/19716268/d7eb1518.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/20000000/19720000/19716300/19716268/d46bbef9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/20000000/19720000/19716300/19716268/4ccd149b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Houston Intercontinental Airport [](https://www.expedia.ca/Houston-Hotels-Courtyard-By-Marriott-Houston-Intercontinental-Airport.h19716268.Hotel-Information) 31.8 km from South Main 9.0/10 Wonderful (1087) "Courteous staff, clean rooms, excellent location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rebecca CA $138 CA $162 total includes taxes & fees Jan 2 - Jan 3, 2026 [](https://www.expedia.ca/Houston-Hotels-Courtyard-By-Marriott-Houston-Intercontinental-Airport.h19716268.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1560000/1558900/1558836/414e86df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1560000/1558900/1558836/dea49ca8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1560000/1558900/1558836/b27ae005.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/2000000/1560000/1558900/1558836/32c69422.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Houston-Bush Intercontinental Aprt [](https://www.expedia.ca/Houston-Hotels-Hampton-Inn-Suites-Houston-Bush-Intercontinental-Airport.h1558836.Hotel-Information) 31.8 km from South Main 8.8/10 Excellent (1721) "Nice hotel, the staff was very friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra CA $101 CA $118 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Houston-Hotels-Hampton-Inn-Suites-Houston-Bush-Intercontinental-Airport.h1558836.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/910000/907500/907459/024118ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/910000/907500/907459/519371f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/910000/907500/907459/9aaf511c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/910000/907500/907459/0b2adb37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Magnolia Hotel Houston, A Tribute Portfolio Hotel [](https://www.expedia.ca/Houston-Hotels-Magnolia-Hotel-Houston.h907459.Hotel-Information) Downtown Houston, 11.1 km from South Main 9.2/10 Wonderful (1356) "Bed was very nice and comfortable! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Luis CA $165 CA $197 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Houston-Hotels-Magnolia-Hotel-Houston.h907459.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2970000/2964300/2964240/69d373fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/3000000/2970000/2964300/2964240/1943a3b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/3000000/2970000/2964300/2964240/112034c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/3000000/2970000/2964300/2964240/1da2c869.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Houston Intercontinental Arprt [](https://www.expedia.ca/Houston-Hotels-SpringHill-Suites-By-Marriott-Houston-Intercontinental-Arprt.h2964240.Hotel-Information) 31.8 km from South Main 9.0/10 Wonderful (1606) "It was a great stay. Efficient, nice staff and clean room. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) roham CA $127 CA $148 total includes taxes & fees Jan 2 - Jan 3, 2026 [](https://www.expedia.ca/Houston-Hotels-SpringHill-Suites-By-Marriott-Houston-Intercontinental-Arprt.h2964240.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1250000/1240800/1240788/6790494a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1250000/1240800/1240788/w800h584x0y0-b8e2ff5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/2000000/1250000/1240800/1240788/2f365084.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1250000/1240800/1240788/e821a958.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Platinum Inn & Suites Webster [](https://www.expedia.ca/Houston-Hotels-Platinum-Inn-Suites-Webster.h1240788.Hotel-Information) 30.8 km from South Main 7.8/10 Good (1006) "It was a great stay just perfect" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) elvin CA $75 CA $88 total includes taxes & fees Dec 29 - Dec 30 [](https://www.expedia.ca/Houston-Hotels-Platinum-Inn-Suites-Webster.h1240788.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/77443f8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, rooftop bar](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/9ca7dbb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/e15c188d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, rooftop bar](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/280705eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Houston Plaza/Medical Center [](https://www.expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) 4.4 km from South Main 8.4/10 Very good (1783) "The hotel was great and convenient. Easy check in an check out. Will definitely stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Allison CA $120 CA $141 total includes taxes & fees Jan 3 - Jan 4, 2026 [](https://www.expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) ![Lounge](https://images.trvl-media.com/lodging/45000000/44400000/44399600/44399547/c04e5fd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/45000000/44400000/44399600/44399547/0c065c18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed with Sofa bed, City View](https://images.trvl-media.com/lodging/45000000/44400000/44399600/44399547/7be25f35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/45000000/44400000/44399600/44399547/66ed2c1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Houston Downtown [](https://www.expedia.ca/Houston-Hotels-Hyatt-Place-Houston-Downtown.h44399547.Hotel-Information) Houston Central Business District, 11 km from South Main 9.0/10 Wonderful (1573) "Great service, room was relaxing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alice CA $130 CA $156 total includes taxes & fees Dec 25 - Dec 26 [](https://www.expedia.ca/Houston-Hotels-Hyatt-Place-Houston-Downtown.h44399547.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/w3837h2505x3y0-1cfabad9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/w3837h2768x3y3-aed6fd99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/w3837h2340x3y0-41c8f6ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, individually decorated](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/1d5101c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Blossom Hotel Houston, Curio Collection by Hilton [](https://www.expedia.ca/Houston-Hotels-Blossom-Hotel-Houston.h58985846.Hotel-Information) Texas Medical Center, 3.5 km from South Main 9.0/10 Wonderful (3624) "Cute hotel, very clean and friendly staff. We enjoyed our stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alison CA $178 CA $209 total includes taxes & fees Jan 18 - Jan 19, 2026 [](https://www.expedia.ca/Houston-Hotels-Blossom-Hotel-Houston.h58985846.Hotel-Information) ![Snack bar](https://images.trvl-media.com/lodging/25000000/24160000/24152700/24152630/97731659.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/25000000/24160000/24152700/24152630/c9ac0936.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/25000000/24160000/24152700/24152630/d069ec9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/25000000/24160000/24152700/24152630/a3abdbe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Houston Hobby Airport, TX [](https://www.expedia.ca/Houston-Hotels-Hilton-Garden-Inn-Houston-Hobby-Airport.h24152630.Hotel-Information) 15 km from South Main 8.8/10 Excellent (1000) "Staff was great and ver helpful. Food was amazing and I would stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Arlyne CA $117 CA $137 total includes taxes & fees Dec 31 - Jan 1, 2026 [](https://www.expedia.ca/Houston-Hotels-Hilton-Garden-Inn-Houston-Hobby-Airport.h24152630.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20200/20116/109ddc6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/1000000/30000/20200/20116/555244ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down comforters, cribs/infant beds, WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/20200/20116/f197bbe2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/30000/20200/20116/aa597850.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Hotel & Suites Houston by the Galleria [](https://www.expedia.ca/Houston-Hotels-DoubleTree-By-Hilton-Hotel-Suites-Houston-By-The-Galleria.h20116.Hotel-Information) 8.9 km from South Main 8.2/10 Very good (3147) "Friendly staff and great location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tim CA $173 CA $204 total includes taxes & fees Jan 2 - Jan 3, 2026 [](https://www.expedia.ca/Houston-Hotels-DoubleTree-By-Hilton-Hotel-Suites-Houston-By-The-Galleria.h20116.Hotel-Information) ![Outdoor pool, open 6:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/11000000/10630000/10620700/10620692/9a708987.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed](https://images.trvl-media.com/lodging/11000000/10630000/10620700/10620692/0d05fbc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/11000000/10630000/10620700/10620692/089b4167.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/11000000/10630000/10620700/10620692/w3839h2558x0y0-a752fdd8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Houston/Galleria [](https://www.expedia.ca/Houston-Hotels-Hyatt-Regency-HoustonGalleria.h10620692.Hotel-Information) The Galleria, 8.7 km from South Main 9.0/10 Wonderful (1181) "Great property! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lynn CA $145 CA $211 total includes taxes & fees Jan 8 - Jan 9, 2026 [](https://www.expedia.ca/Houston-Hotels-Hyatt-Regency-HoustonGalleria.h10620692.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/36000000/35560000/35559700/35559679/12d2dec5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/36000000/35560000/35559700/35559679/252267a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/36000000/35560000/35559700/35559679/cfcd37d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/36000000/35560000/35559700/35559679/beac9be3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cambria Hotel Houston Downtown Convention Center [](https://www.expedia.ca/Houston-Hotels-Cambria-Hotel-Houston-Downtown-Convention-Center.h35559679.Hotel-Information) Houston Central Business District, 11 km from South Main 8.8/10 Excellent (1700) "Beautiful stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lillian CA $136 CA $159 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Houston-Hotels-Cambria-Hotel-Houston-Downtown-Convention-Center.h35559679.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-07&endDate=2026-01-08®ionId=553248635976386992&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in South Main Find the best South Main areas and neighborhoods for the activities you enjoy most. - Downtown Houston - The Galleria - Texas Medical Center - Northside - Houston Heights ![Discovery Green which includes city views, a square or plaza and a skyscraper](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/23000/23540-Discovery-Green.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Discovery Green showing a park, a skyscraper and street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/34000/34453-Discovery-Green.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/507000/507468-downtown-houston.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/507000/507497-downtown-houston.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![Discovery Green showing a statue or sculpture, a high-rise building and modern architecture](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/34000/34451-Discovery-Green.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=800037) ![Downtown Houston map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:s%7CrtDz%7BbeQiQ_%40eEcBgCkDuQ%7D_%40m%5EeQ%7EMi%5DoAePiLi%60%40m%40%7DTlCsl%40pNj%5CxWzUxS%60Bv%7CAhmAcg%40ncAuI%60DmZx%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=WgKNf3zxiTWREKGzy8I1t3uy5Hs=) ### Downtown Houston Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines. [See properties](https://www.expedia.ca/Hotel-Search?regionId=800037) ![](https://mediaim.expedia.com/destination/1/733d46a93b53c864b5c00945f6416b51.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/d7dc12b9d267be169566d38db8ea7eac.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/7/01538c9f6eb646ea96e3df2059618b27.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/7/374a9a687602bd093583e97522a04bc6.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/9/aadfd687906d99829a520409ec046d47.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=501263) ![The Galleria map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7DxptDn%7DteQ_AcXqKr%40mHsB%7BXT%5DgYeZY%3F%7D%60%40jGi%40rA_HxCyFTuIpzAsBbBt%7D%40fw%40%60NdA%7Ce%40szAdB&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=5e77b0krOIeDwBK5_jkO84swezY=) ### The Galleria Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower. [See properties](https://www.expedia.ca/Hotel-Search?regionId=501263) ![](https://mediaim.expedia.com/destination/1/f4655cac96c82fca6c00f4ab3162178c.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/7/29187be13ac57fa24b0f672247c7afbc.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/7/52a59f2a0bfb2cf153bbc44f917f7275.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/9/921ad7f5733a42c9202d8d16c78f3830.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=6143504) ![Texas Medical Center map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:wbftD%7C%60keQyBu%40u%5DkXgZySqC%7EG%7DEnG%7DQrDyAw%60%40aa%40gYrCsKe%5BcW%7CM_UbGi%40%60LmLjQmE%5DmPvB%60%40vEoQhGyJnDgKjKlC%7DDbTqAUq%40lDrYtHbGdd%40nKsDlOe%40bW%60Oj%40d_%40%7BFd%40%3FdRmCpA%3FdAtC%7CDL%60_%40eF%3F%7B%40uFiDf%40AqAwBB%7BC%60Ae%40yCm%40OlBhOjId%60%40hAnC&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=-txg4h32BKxrIPBjQzTWKWRnz0I=) ### Texas Medical Center Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience. [See properties](https://www.expedia.ca/Hotel-Search?regionId=6143504) ![](https://mediaim.expedia.com/destination/7/b249298face16fd5795cf74face8ed8d.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/7/7f180593ef78263134eb6f20e72fd6c3.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976387525) ![Northside map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:muquD%60e%7DeQS_uAwHCiF%7B%40eOkIi%40dAf%40oAhOnIfFz%40%7CHB%3Ff%40bqCs%40%3FqP%7CBA%3FgKkUFzCeb%40%60u%40%5BJlx%40tq%40%3FV%7BOrD_GhAsKxG%7BG%40aB%7DS%7CJwIgSn%5Bo%5Bc%60A%5EUanAmEqAsFwCcGr%40yITqExA%7BBMQkXpJAEkNiFDBaS%7EFaJ%7E%5Eq%5EoBszBgmA%5Ci%40myAgFF%3FeAiDFIoIsYFYcEaBmFuoAj%40eaAgCNf%60%40__AZZzv%40hGx%5Ez%40VJvAk%40l%40HnI%7DQD%40pkA%60%40rMqSJ%3FfEoB%40AgEsKB_%40k%7EAaEyFoC%3F_EkEcEuCtCAY_SmKBBbIqHDgDgDu%40mBGcFnPF%60J_%40CwLqy%40ZD%7Ef%40aG%40%40tMw%40bJEvGcq%40RJyg%40aLC%3FsBzBcFjHC%3Fs%5DkFnBwCxBiS%60W_D%3FW%7Bl%40zd%40mG%3FmGlLM%3FbD%7ENoBhi%40i%40bVaArH%7D%40o%40geB%7DXJMif%40fJGUux%40tdCy_%40vB%7ERj%40dRlOEDtK%7BOHC%7EKnBA%40%7CK%60bBi%40x%40dbBpIVltA%7D%40jIn%40nmCg%40i%40mgCOgAiM%7EG%5D%7BqAmFC%3FrCcHA%40nC%7D%5E%40CaQaVT%40%5EsNaMoARg%40wGj%5DwEl%60A%7DOOe%5D%7EHAHzZdScDvJVw%40csCiLcAcDfBcDf%40Iyh%40jVOHwZvZvNMqfBayCg%7D%40Sc%60%40kq%40E%40u%40%7DF%40AqEyP%3FKkWkZNI%7DZee%40Zl%40eF%7CBC%40%60C%60D%3FGiVxpAk%40NpO%60KIPbn%40ve%40O%5Bqz%40jd%40OEya%40vLEAmHts%40W%5Da_B%60lCrjCjZ_CtfB%7CAXsObgDc%40JxYj%5E%5EpaAzrCvuCXjEtQfl%40vZqG%60R%7DN%7EP%7C%40%7CUhHdSmSrCuBzWvDzNeEbf%40uYnGwRwe%40cCd_ArSfu%40s%60%40%7E%60%40u_%40%7EZiKhk%40dQtm%40uAxaB_JDIpSkK%7CJfFfLC%7EHsK%7DBku%40dDj%40fJaLmAApX%7CLxDcItPeIlFuF%7CNkc%40fN%7BOpNoA%7E%5BsLdPiPjb%40ut%40nYq%40ti%40gNr%5EbAlaAsfC%7EwCkDKw%40mJtCcGavBu%40aZuJoEBn%40%7C%7EAyq%40%5CgCp%5C%7B%60B%3F%5DcfAgwCbuA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=SL4qRZsnUhbIVHkfA1was5maM1w=) ### Northside While you're in Northside, take in top sights like The Heights Theater or Greenspoint Mall, and hop on the metro to see more the city at Northline Transit Center/HCC Station or Melbourne/North Lindale Station. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976387525) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248633938962798) ![Houston Heights map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7B%7DvtD%60jkeQe%5DSwm%40uIujC%7EF%5D%7B%7DBkC_Ne%40sSly%40oTpkCmAnIgCrJr%40%60Br%40vH%7EFm%40rkBN%7C%60%40%7BHdg%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=opqAVmz9leLiGgUlmOqGYTLlj10=) ### Houston Heights You'll enjoy the coffeehouses and live music in Houston Heights. You might want to make time for a stop at The Heights Theater or Artcar Museum. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248633938962798) ## Top South Main Hotel Reviews ![Blossom Hotel Houston, Curio Collection by Hilton](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/db7ae93f_y.jpg) ### Blossom Hotel Houston, Curio Collection by Hilton 10/10 Excellent "Amazing hotel. People were very polite. " [](https://expedia.ca/Houston-Hotels-Blossom-Hotel-Houston.h58985846.Hotel-Information) ![DoubleTree by Hilton Hotel & Suites Houston by the Galleria](https://images.trvl-media.com/lodging/1000000/30000/20200/20116/555244ce_y.jpg) ### DoubleTree by Hilton Hotel & Suites Houston by the Galleria 10/10 Excellent "Very spacious room, quiet area and hotel staff were great " [](https://expedia.ca/Houston-Hotels-DoubleTree-By-Hilton-Hotel-Suites-Houston-By-The-Galleria.h20116.Hotel-Information) ![Magnolia Hotel Houston, A Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/1000000/910000/907500/907459/0b2adb37_y.jpg) ### Magnolia Hotel Houston, A Tribute Portfolio Hotel 10/10 Excellent "great location and wonderful pool, breakfast and beds." [](https://expedia.ca/Houston-Hotels-Magnolia-Hotel-Houston.h907459.Hotel-Information) ![Holiday Inn Houston Downtown by IHG](https://images.trvl-media.com/lodging/9000000/8170000/8168200/8168134/f5ea3a06_y.jpg) ### Holiday Inn Houston Downtown by IHG 10/10 Excellent "Good place to stay. Front desk was helpful for places to go to try. A little out of the way for night life but good price. " [](https://expedia.ca/Houston-Hotels-Holiday-Inn-Houston-Downtown.h8168134.Hotel-Information) ![Hilton Americas-Houston](https://images.trvl-media.com/lodging/1000000/980000/976200/976144/09dd0b59_y.jpg) ### Hilton Americas-Houston 10/10 Excellent "The room was peefect with a great view. Every staff memeber was courteous and made sure we were enjoying oyr stay." [](https://expedia.ca/Houston-Hotels-Hilton-Americas-Houston.h976144.Hotel-Information) ![Heritage Place Houston Brookhollow](https://images.trvl-media.com/lodging/1000000/10000/6300/6298/90f3bec7_y.jpg) ### Heritage Place Houston Brookhollow 10/10 Excellent "Great staff and the room was very clean" [](https://expedia.ca/Houston-Hotels-Heritage-Place-Houston-Brookhollow.h6298.Hotel-Information) ![Club Quarters Hotel Downtown, Houston](https://images.trvl-media.com/lodging/2000000/1160000/1157000/1156923/44a9a3fd_y.jpg) ### Club Quarters Hotel Downtown, Houston 10/10 Excellent "Excellent stay! The hotel was decorated elegantly for the holidays and I was offered a room upgrade due to an issue with the kiosk saying the room was not ready even though it was after 3 pm which is check in time. The Rusk rooms were very accommodating and spacious. I especially enjoyed the view of Daikin Park. It was a lovely stay!" [](https://expedia.ca/Houston-Hotels-Club-Quarters-Hotel-In-Houston.h1156923.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Houston Bush IAH South](https://images.trvl-media.com/lodging/1000000/170000/165600/165562/0afb5a51_y.jpg) ### La Quinta Inn & Suites by Wyndham Houston Bush IAH South 10/10 Excellent "Very good experience" [](https://expedia.ca/Houston-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Houston-Bush-IAH-South.h165562.Hotel-Information) ![Hilton Houston Plaza/Medical Center](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/294f3d50_y.jpg) ### Hilton Houston Plaza/Medical Center 10/10 Excellent "Great" [](https://expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) ## Frequently asked questions ### What are the best hotels in South Main that travellers recommend? > For families, [Wingate Houston near NRG Park/Medical Center](https://www.expedia.ca/Houston-Hotels-Wingate-By-Wyndham-Houston-Reliant-Medical-Center.h66022895.Hotel-Information) is another great option. With a complimentary continental breakfast to fuel your adventures and a refreshing outdoor pool, it caters superbly to parents and kids alike. The accessible fitness centre allows for some family fun, while the hotel's pet-friendly policies make it a fantastic choice for those traveling with furry companions. With a focus on convenience and value, this hotel provides excellent amenities while keeping everyone comfortable. ### What are the best family hotels in South Main? > Another excellent option is the [Candlewood Suites Houston Medical Center by IHG](https://www.expedia.ca/Houston-Hotels-Candlewood-Suites-Houston-Medical-Center.h2227000.Hotel-Information), which boasts a family-friendly atmosphere with its free cribs, connecting rooms, and a sofa bed, making it great for families needing extra space. Guests appreciate the convenience of in-room kitchen amenities like a microwave and dishwasher, allowing for easy meal prep during your stay. It has a review score of 7.6, reflecting its appeal to families on the go. > > > For those seeking a place with a pool, the [Quality Inn & Suites NRG Park - Medical Center](https://www.expedia.ca/Houston-Hotels-Quality-Inn-Suites-NRG-Park-Medical-Center.h17531.Hotel-Information) is a great choice. With its inviting pool area, free meals for children, and options for rollaway beds at no extra charge, families can enjoy a splash-filled vacation while also benefiting from daily housekeeping and snack options. > > > Lastly, the [Wyndham Houston near NRG Park/Medical Center](https://www.expedia.ca/Houston-Hotels-Wyndham-Houston-Near-NRG-ParkMedical-Center.h21297.Hotel-Information) features child-friendly window designs and connecting rooms, catering specifically to families' needs. The presence of kitchenettes adds to the convenience, allowing families to prepare snacks or meals together. This property has a traveller rating of 7.2, making it a reliable choice for family stays. > > > These hotels exemplify quality and convenience, ensuring that your family's adventure in South Main is both enjoyable and comfortable. ### What hotels in South Main offer free breakfast? > Another great choice is [Quality Inn & Suites NRG Park - Medical Center](https://www.expedia.ca/Houston-Hotels-Quality-Inn-Suites-NRG-Park-Medical-Center.h17531.Hotel-Information), which also provides a free breakfast, including options for those on the go. This family-friendly hotel offers spacious suites with balconies and patios, allowing families to unwind outdoors. The outdoor pool invites guests to relax and enjoy the Texas sunshine, while the complimentary area shuttle makes it simple to explore the attractions nearby. > > > For those traveling without children, the [Wingate Houston near NRG Park/Medical Center](https://www.expedia.ca/Houston-Hotels-Wingate-By-Wyndham-Houston-Reliant-Medical-Center.h66022895.Hotel-Information) presents a delightful blend of comfort and accessibility. With an outdoor pool and fitness centre, it caters to adults looking for a rejuvenating getaway. The hotel's continental breakfast is another perk that guarantees a satisfying start to your morning adventures. ### What are the best budget hotels in South Main? > For another appealing choice, [Candlewood Suites Houston Medical Center by IHG](https://www.expedia.ca/Houston-Hotels-Candlewood-Suites-Houston-Medical-Center.h2227000.Hotel-Information) stands out with a review score of 7.6\. This property is superb for families, as it features kitchenettes in the rooms, allowing for meal preparation and snacks on the go. Kids can also enjoy the complimentary cribs and sofa beds, making it a comfortable stay for everyone. Additionally, the hotel offers a free area shuttle, which is great for exploring local attractions without the hassle of driving. > > > If you're traveling with your partner or friends, the [Wyndham Houston near NRG Park/Medical Center](https://www.expedia.ca/Houston-Hotels-Wyndham-Houston-Near-NRG-ParkMedical-Center.h21297.Hotel-Information) offers a more relaxed atmosphere with a lower review score of 7.2\. This hotel features outdoor pool access and convenient amenities, including a kitchenette in some rooms, which can appeal to those looking for a home-like experience while away. > > > No matter your travel group, these options in South Main cater to various needs while ensuring a comfortable and enjoyable stay. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a South Main hotel booking with Expedia? ### How much is the nightly rate at a South Main hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [Casino Hotels in Astrodome ](https://www.expedia.ca/Astrodome-Houston-Hotels-Casino-Hotel.0-n553248635976007975-0-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Astrodome ](https://www.expedia.ca/Astrodome-Houston-Hotels-Cheap-Hotels.0-n553248635976007975-0-tCheapHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Astrodome ](https://www.expedia.ca/Astrodome-Houston-Hotels-Luxury-Hotel.0-n553248635976007975-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - 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