Title: 10 Best Hotels in South Main, Houston for 2026 | Expedia.ca

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## Check prices for these dates

Tonight

[Jan 17 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2026-01-17&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Jan 18 - Jan 19](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2026-01-18&endDate=2026-01-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two weeks

[Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=553248635976386992&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Our top choices for South Main hotels

![Individually decorated, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/910000/904200/904192/3aca26b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/910000/904200/904192/d9fe05fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business centre](https://images.trvl-media.com/lodging/1000000/910000/904200/904192/ba5d9607.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/910000/904200/904192/28e82f54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Suites Houston near Medical Center- NRG Stadium

[](https://www.expedia.ca/Houston-Hotels-Comfort-Suites-Near-Texas-Medical-Center-NRG-Stadium.h904192.Hotel-Information)

South Main

8.6/10

Excellent

(1,001 reviews)

"Clean room, helpful staff and good location to hospital."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

George

CA $119

CA $139 total

includes taxes & fees

Jan 18 - Jan 19

[](https://www.expedia.ca/Houston-Hotels-Comfort-Suites-Near-Texas-Medical-Center-NRG-Stadium.h904192.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/168bdeac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full-size fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/14da1a00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/2693cb6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/3000000/2230000/2227000/2227000/27e929b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Candlewood Suites Houston Medical Center by IHG

[](https://www.expedia.ca/Houston-Hotels-Candlewood-Suites-Houston-Medical-Center.h2227000.Hotel-Information)

South Main

7.4/10

Good

(829 reviews)

"This is a safe, friendly hotel close to MDA Cancer Center"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Myra

CA $108

CA $127 total

includes taxes & fees

Jan 21 - Jan 22

[](https://www.expedia.ca/Houston-Hotels-Candlewood-Suites-Houston-Medical-Center.h2227000.Hotel-Information)

![Hypo-allergenic bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/20000/17600/17531/2ae57d48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/17600/17531/23f0ff28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/17600/17531/63621dad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/20000/17600/17531/78978179.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn & Suites NRG Park - Medical Center

[](https://www.expedia.ca/Houston-Hotels-Quality-Inn-Suites-NRG-Park-Medical-Center.h17531.Hotel-Information)

South Main

6.6/10

(1,000 reviews)

"Clean rooms, quiet property. We will be back again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Javier

CA $105

CA $123 total

includes taxes & fees

Jan 25 - Jan 26

[](https://www.expedia.ca/Houston-Hotels-Quality-Inn-Suites-NRG-Park-Medical-Center.h17531.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/eca4a935.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/dec1e7ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/6b2e094a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/67000000/66030000/66022900/66022895/d00107cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Wingate Houston near NRG Park/Medical Center

[](https://www.expedia.ca/Houston-Hotels-Wingate-By-Wyndham-Houston-Reliant-Medical-Center.h66022895.Hotel-Information)

South Main

6.6/10

(996 reviews)

"Easy access to stadium "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Richard

CA $151

CA $177 total

includes taxes & fees

Jan 21 - Jan 22

[](https://www.expedia.ca/Houston-Hotels-Wingate-By-Wyndham-Houston-Reliant-Medical-Center.h66022895.Hotel-Information)

![Premium bedding, pillowtop beds, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/99a71929.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Food and drink](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/83265e97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/w2558h1440x0y0-44773629.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 10:00 AM to 6:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/21300/21297/e04a9b51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Wyndham Houston near NRG Park/Medical Center

[](https://www.expedia.ca/Houston-Hotels-Wyndham-Houston-Near-NRG-ParkMedical-Center.h21297.Hotel-Information)

South Main

7.2/10

Good

(1,206 reviews)

"Front desk staff was very professional and kind."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

MARINA

CA $179

CA $210 total

includes taxes & fees

Jan 21 - Jan 22

[](https://www.expedia.ca/Houston-Hotels-Wyndham-Houston-Near-NRG-ParkMedical-Center.h21297.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/19000000/18280000/18277900/18277884/bb9ff62c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/19000000/18280000/18277900/18277884/2c37cb5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/19000000/18280000/18277900/18277884/c96656bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/19000000/18280000/18277900/18277884/12bf78b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Four Points by Sheraton Houston Intercontinental Airport

[](https://www.expedia.ca/Houston-Hotels-Four-Points-By-Sheraton-Houston-Intercontinental-Airport.h18277884.Hotel-Information)

29.9 km from South Main

8.4/10

Very good

(1,005 reviews)

"This place was amazing! Stayed in 4 places in days, this was the absolute best !"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Debra

CA $117

CA $137 total

includes taxes & fees

Jan 30 - Jan 31

[](https://www.expedia.ca/Houston-Hotels-Four-Points-By-Sheraton-Houston-Intercontinental-Airport.h18277884.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/800000/791700/791616/208536ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/800000/791700/791616/53da42be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/800000/791700/791616/9780f8b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/800000/791700/791616/b0807f21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Suites Houston West at Clay Road

[](https://www.expedia.ca/Houston-Hotels-Comfort-Suites-Houston-West-At-Clay-Road.h791616.Hotel-Information)

22.8 km from South Main

8.4/10

Very good

(1,001 reviews)

"Safe hotel"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nick

CA $102

CA $119 total

includes taxes & fees

Jan 29 - Jan 30

[](https://www.expedia.ca/Houston-Hotels-Comfort-Suites-Houston-West-At-Clay-Road.h791616.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/870000/861200/861181/ac258be9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/870000/861200/861181/w3839h2557x0y0-d53d3caa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/870000/861200/861181/f2c86566.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/870000/861200/861181/w3840h2557x0y0-0cc1eb32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Garden Inn Houston/Bush Intercontinental Airport

[](https://www.expedia.ca/Houston-Hotels-Hilton-Garden-Inn-HoustonBush-Intercontinental-Airport.h861181.Hotel-Information)

31.1 km from South Main

8.4/10

Very good

(1,001 reviews)

"It was a great stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Thrideep

CA $121

CA $142 total

includes taxes & fees

Feb 7 - Feb 8

[](https://www.expedia.ca/Houston-Hotels-Hilton-Garden-Inn-HoustonBush-Intercontinental-Airport.h861181.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41300/41223/8d7f6d72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/41300/41223/275afa90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/50000/41300/41223/34eccf2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/1000000/50000/41300/41223/018af26d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### GreenTree Inn Houston IAH Airport

[](https://www.expedia.ca/Houston-Hotels-GreenTree-Inn-Houston-IAH-Airport.h41223.Hotel-Information)

31.4 km from South Main

6.6/10

(1,002 reviews)

"It was ok, to spend a night waiting for a flight. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Hamlet

CA $75

CA $88 total

includes taxes & fees

Jan 18 - Jan 19

[](https://www.expedia.ca/Houston-Hotels-GreenTree-Inn-Houston-IAH-Airport.h41223.Hotel-Information)

![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/2000000/1320000/1319100/1319026/2484fc7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1320000/1319100/1319026/79159862.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/2000000/1320000/1319100/1319026/45618e3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1320000/1319100/1319026/5d443bd8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Days Inn & Suites by Wyndham Houston Hobby Airport

[](https://www.expedia.ca/Houston-Hotels-Days-Inn-Suites-By-Wyndham-Houston-Hobby-Airport.h1319026.Hotel-Information)

15.8 km from South Main

8.6/10

Excellent

(1,002 reviews)

"Awesome friendly staff and spotless rooms. Kudos to the manager."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mauricio

CA $103

CA $120 total

includes taxes & fees

Jan 21 - Jan 22

[](https://www.expedia.ca/Houston-Hotels-Days-Inn-Suites-By-Wyndham-Houston-Hobby-Airport.h1319026.Hotel-Information)

![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/16000000/15970000/15963500/15963494/d46c6c32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Flat-screen TV](https://images.trvl-media.com/lodging/16000000/15970000/15963500/15963494/1483444b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/16000000/15970000/15963500/15963494/f8eae0ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/16000000/15970000/15963500/15963494/6634f188.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn & Suites Houston I-10 West Park Row

[](https://www.expedia.ca/Houston-Hotels-Hampton-Inn-Suites-Houston-I-10-West-Park-Row.h15963494.Hotel-Information)

29.3 km from South Main

8.8/10

Excellent

(673 reviews)

"Great staff, Clean room. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Corliss

CA $100

CA $118 total

includes taxes & fees

Jan 23 - Jan 24

[](https://www.expedia.ca/Houston-Hotels-Hampton-Inn-Suites-Houston-I-10-West-Park-Row.h15963494.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/7000000/6120000/6117600/6117517/df115a5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/7000000/6120000/6117600/6117517/c755cb25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business centre](https://images.trvl-media.com/lodging/7000000/6120000/6117600/6117517/24f15a7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/7000000/6120000/6117600/6117517/4f616ded.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham Houston NW Beltway8/WestRD

[](https://www.expedia.ca/Houston-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Houston-NW-Beltway8WestRD.h6117517.Hotel-Information)

28.8 km from South Main

9.0/10

Wonderful

(979 reviews)

"Area is nice and quiet. Hotel was clean. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Isabel

CA $110

CA $129 total

includes taxes & fees

Jan 21 - Jan 22

[](https://www.expedia.ca/Houston-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Houston-NW-Beltway8WestRD.h6117517.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25200/25175/8773f9be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/25200/25175/d4725ab9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 6 AM to 11 PM, pool umbrellas](https://images.trvl-media.com/lodging/1000000/30000/25200/25175/1b8be4fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/30000/25200/25175/f42c7206.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### DoubleTree by Hilton Houston Intercontinental Airport

[](https://www.expedia.ca/Houston-Hotels-DoubleTree-By-Hilton-Houston-Intercontinental-Airport.h25175.Hotel-Information)

31.5 km from South Main

8.4/10

Very good

(1,002 reviews)

"Clean rooms, friendly staff. Yummy warm cookies upon checkin! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Amanda

CA $181

CA $212 total

includes taxes & fees

Feb 1 - Feb 2

[](https://www.expedia.ca/Houston-Hotels-DoubleTree-By-Hilton-Houston-Intercontinental-Airport.h25175.Hotel-Information)

![Reception hall](https://images.trvl-media.com/lodging/19000000/18130000/18122200/18122141/6b120e5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/19000000/18130000/18122200/18122141/4621f83c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free self parking](https://images.trvl-media.com/lodging/19000000/18130000/18122200/18122141/597b2a2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/19000000/18130000/18122200/18122141/f0057a90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Haven Inn & Suites Downtown Houston

[](https://www.expedia.ca/Houston-Hotels-Haven-Inn-Suites-Downtown-Houston.h18122141.Hotel-Information)

North Houston, 18.7 km from South Main

9.4/10

Exceptional

(1,002 reviews)

"Better breakfast options. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Cecilia

CA $83

CA $98 total

includes taxes & fees

Jan 25 - Jan 26

[](https://www.expedia.ca/Houston-Hotels-Haven-Inn-Suites-Downtown-Houston.h18122141.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/91000000/90620000/90610800/90610782/70356f9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/91000000/90620000/90610800/90610782/fd82b197.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/91000000/90620000/90610800/90610782/92a37ac8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/91000000/90620000/90610800/90610782/9dc4499b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Moxy Houston Downtown

[](https://www.expedia.ca/Houston-Hotels-Moxy-Houston-Downtown.h90610782.Hotel-Information)

Downtown Houston, 11.2 km from South Main

8.8/10

Excellent

(712 reviews)

"Staff was very pleasant and the rooms were clean."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Elizabeth

CA $137

CA $164 total

includes taxes & fees

Jan 19 - Jan 20

[](https://www.expedia.ca/Houston-Hotels-Moxy-Houston-Downtown.h90610782.Hotel-Information)

![Lobby lounge](https://images.trvl-media.com/lodging/4000000/3930000/3920400/3920333/1de4f09b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pillowtop beds, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/4000000/3930000/3920400/3920333/320fc3c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/4000000/3930000/3920400/3920333/8c9a7614.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/4000000/3930000/3920400/3920333/5cd32cb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Four Points by Sheraton Houston Hobby Airport

[](https://www.expedia.ca/Houston-Hotels-Four-Points-By-Sheraton-Houston-Hobby-Airport.h3920333.Hotel-Information)

Southeast Houston, 15.3 km from South Main

7.8/10

Good

(1,001 reviews)

"Staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Omolara

CA $82

CA $96 total

includes taxes & fees

Jan 21 - Jan 22

[](https://www.expedia.ca/Houston-Hotels-Four-Points-By-Sheraton-Houston-Hobby-Airport.h3920333.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/19000000/18570000/18567500/18567471/9e6395d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/19000000/18570000/18567500/18567471/fc700d7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/19000000/18570000/18567500/18567471/c144feb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/19000000/18570000/18567500/18567471/ceeca200.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### WoodSpring Suites Houston Northwest

[](https://www.expedia.ca/Houston-Hotels-WoodSpring-Suites-Houston-Northwest.h18567471.Hotel-Information)

23.8 km from South Main

7.6/10

Good

(517 reviews)

"Great experience!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Bryant

CA $85

CA $97 total

includes taxes & fees

Jan 21 - Jan 22

[](https://www.expedia.ca/Houston-Hotels-WoodSpring-Suites-Houston-Northwest.h18567471.Hotel-Information)

![Snack bar](https://images.trvl-media.com/lodging/25000000/24160000/24152700/24152630/97731659.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/25000000/24160000/24152700/24152630/a3abdbe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/25000000/24160000/24152700/24152630/d069ec9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/25000000/24160000/24152700/24152630/d7f5d954.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Garden Inn Houston Hobby Airport, TX

[](https://www.expedia.ca/Houston-Hotels-Hilton-Garden-Inn-Houston-Hobby-Airport.h24152630.Hotel-Information)

15 km from South Main

8.8/10

Excellent

(1,001 reviews)

"Staff was amazing and attentive. Our room was clean, the amenities were enjoyable. We will be back for sure!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

SAMANTHA

CA $127

CA $149 total

includes taxes & fees

Feb 7 - Feb 8

[](https://www.expedia.ca/Houston-Hotels-Hilton-Garden-Inn-Houston-Hobby-Airport.h24152630.Hotel-Information)

![Bar (on property)](https://images.trvl-media.com/lodging/4000000/3880000/3870100/3870088/5c770ddf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/4000000/3880000/3870100/3870088/8821ccc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3880000/3870100/3870088/2149bc64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/4000000/3880000/3870100/3870088/a8ba126b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Embassy Suites Houston Downtown

[](https://www.expedia.ca/Houston-Hotels-Embassy-Suites-Houston-Downtown.h3870088.Hotel-Information)

10.4 km from South Main

9.2/10

Wonderful

(1,004 reviews)

"Staff was courteous at check-in and the room was clean."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ifeanyi

CA $227

CA $265 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/Houston-Hotels-Embassy-Suites-Houston-Downtown.h3870088.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/17000000/16640000/16639100/16639053/e07b99d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily full breakfast](https://images.trvl-media.com/lodging/17000000/16640000/16639100/16639053/52016fe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/17000000/16640000/16639100/16639053/e0216c91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/17000000/16640000/16639100/16639053/a4fc10d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Houston IAH - Beltway 8 by IHG

[](https://www.expedia.ca/Houston-Hotels-Holiday-Inn-Express-Suites-Houston-IAH-Beltway-8.h16639053.Hotel-Information)

29.9 km from South Main

8.2/10

Very good

(1,055 reviews)

"Great place to stay overnight. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Raul

CA $99

CA $116 total

includes taxes & fees

Jan 30 - Jan 31

[](https://www.expedia.ca/Houston-Hotels-Holiday-Inn-Express-Suites-Houston-IAH-Beltway-8.h16639053.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-31&endDate=2026-02-01&regionId=553248635976386992&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Where to stay in South Main

Find the best South Main areas and neighborhoods for the activities you enjoy most. 

- Downtown Houston
- The Galleria
- Texas Medical Center
- Houston Central Business District
- Montrose

![Discovery Green which includes city views, a square or plaza and a skyscraper](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/23000/23540-Discovery-Green.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Discovery Green showing a park, a skyscraper and street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/34000/34453-Discovery-Green.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/507000/507468-downtown-houston.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/507000/507497-downtown-houston.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Discovery Green showing a statue or sculpture, a high-rise building and modern architecture](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/34000/34451-Discovery-Green.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=800037)

![Downtown Houston map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:s%7CrtDz%7BbeQiQ_%40eEcBgCkDuQ%7D_%40m%5EeQ%7EMi%5DoAePiLi%60%40m%40%7DTlCsl%40pNj%5CxWzUxS%60Bv%7CAhmAcg%40ncAuI%60DmZx%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=WgKNf3zxiTWREKGzy8I1t3uy5Hs=)

### Downtown Houston

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=800037)

![](https://mediaim.expedia.com/destination/1/733d46a93b53c864b5c00945f6416b51.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/1/d7dc12b9d267be169566d38db8ea7eac.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/7/01538c9f6eb646ea96e3df2059618b27.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/7/374a9a687602bd093583e97522a04bc6.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/9/aadfd687906d99829a520409ec046d47.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=501263)

![The Galleria map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7DxptDn%7DteQ_AcXqKr%40mHsB%7BXT%5DgYeZY%3F%7D%60%40jGi%40rA_HxCyFTuIpzAsBbBt%7D%40fw%40%60NdA%7Ce%40szAdB&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=5e77b0krOIeDwBK5_jkO84swezY=)

### The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower. 

[See properties](https://www.expedia.ca/Hotel-Search?regionId=501263)

![](https://mediaim.expedia.com/destination/1/f4655cac96c82fca6c00f4ab3162178c.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/7/29187be13ac57fa24b0f672247c7afbc.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/7/52a59f2a0bfb2cf153bbc44f917f7275.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/9/921ad7f5733a42c9202d8d16c78f3830.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=6143504)

![Texas Medical Center map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:wbftD%7C%60keQyBu%40u%5DkXgZySqC%7EG%7DEnG%7DQrDyAw%60%40aa%40gYrCsKe%5BcW%7CM_UbGi%40%60LmLjQmE%5DmPvB%60%40vEoQhGyJnDgKjKlC%7DDbTqAUq%40lDrYtHbGdd%40nKsDlOe%40bW%60Oj%40d_%40%7BFd%40%3FdRmCpA%3FdAtC%7CDL%60_%40eF%3F%7B%40uFiDf%40AqAwBB%7BC%60Ae%40yCm%40OlBhOjId%60%40hAnC&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=-txg4h32BKxrIPBjQzTWKWRnz0I=)

### Texas Medical Center

Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=6143504)

![Houston featuring a city and a skyscraper](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/34000/34818-Houston.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Houston showing night scenes and a sporting event](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/21000/21517-Houston.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

Photo by Greater Houston Convention and Visitors Bureau

![Space Center Houston which includes aircraft](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/34000/34685-Space-Center-Houston.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Houston featuring skyline, a city and modern architecture](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/21000/21508-Houston.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

Photo by Greater Houston Convention and Visitors Bureau

![Houston featuring a garden](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/21000/21512-Houston-Museum-Of-Fine-Arts.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

Photo by Greater Houston Convention and Visitors Bureau (photographer: Rick Gardner)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=553248635976473213)

![Houston Central Business District map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:wfqtD%7EuceQsXeRk%60Ayr%40x%7E%40_jBp%7D%40zp%40qMrVh%5BfUcp%40fqA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=l24t0KYtEnk7l4YWZTxkpNv3bu8=)

### Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Main Street Square Station. 

[See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976473213)

![Menil Collection which includes interior views and art](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/23000/23619-Menil-Collection.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Menil Collection featuring interior views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/23000/23623-Menil-Collection.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Menil Collection showing interior views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/34000/34667-Menil-Collection.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![Menil Collection featuring a garden](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/34000/34665-Menil-Collection.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/34000/34668-Menil-Collection.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=3000663145)

![Montrose map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:wiptDf%7CieQmBWy%7E%40R%7BAe%40qByG_CiCwQJiG%60%40X%7BBoAyGIeOwDsLe%40qDh%40uJ%7D%40sCSsDuCkJJyE%60AsGLaMnD%7DQBcLreAQGwItTKI_MvFAb%40a%40rNdApW%40nf%40l%5D%60BlBnFpdBf%40tTElUyoA%5C&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=FA9GMjOoslAVD7SwHDyMnspJbfU=)

### Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area. 

[See properties](https://www.expedia.ca/Hotel-Search?regionId=3000663145)

## Top South Main Hotel Reviews

![Hilton Americas-Houston](https://images.trvl-media.com/lodging/1000000/980000/976200/976144/09dd0b59_y.jpg)

### Hilton Americas-Houston

10/10 Excellent

"Always a comfortable visit "

[](https://expedia.ca/Houston-Hotels-Hilton-Americas-Houston.h976144.Hotel-Information)

![Magnolia Hotel Houston, A Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/1000000/910000/907500/907459/0b2adb37_y.jpg)

### Magnolia Hotel Houston, A Tribute Portfolio Hotel

10/10 Excellent

"Greatness …"

[](https://expedia.ca/Houston-Hotels-Magnolia-Hotel-Houston.h907459.Hotel-Information)

![Heritage Place Houston Brookhollow](https://images.trvl-media.com/lodging/1000000/10000/6300/6298/90f3bec7_y.jpg)

### Heritage Place Houston Brookhollow

10/10 Excellent

"Great stay"

[](https://expedia.ca/Houston-Hotels-Heritage-Place-Houston-Brookhollow.h6298.Hotel-Information)

![DoubleTree by Hilton Hotel & Suites Houston by the Galleria](https://images.trvl-media.com/lodging/1000000/30000/20200/20116/555244ce_y.jpg)

### DoubleTree by Hilton Hotel & Suites Houston by the Galleria

10/10 Excellent

"Great location "

[](https://expedia.ca/Houston-Hotels-DoubleTree-By-Hilton-Hotel-Suites-Houston-By-The-Galleria.h20116.Hotel-Information)

![Holiday Inn Houston Downtown by IHG](https://images.trvl-media.com/lodging/9000000/8170000/8168200/8168134/f5ea3a06_y.jpg)

### Holiday Inn Houston Downtown by IHG

10/10 Excellent

"yes"

[](https://expedia.ca/Houston-Hotels-Holiday-Inn-Houston-Downtown.h8168134.Hotel-Information)

![The Royal Sonesta Houston Galleria](https://images.trvl-media.com/lodging/1000000/880000/878700/878652/9874e960_y.jpg)

### The Royal Sonesta Houston Galleria

10/10 Excellent

"Great stay "

[](https://expedia.ca/Houston-Hotels-Royal-Sonesta-Houston-Galleria.h878652.Hotel-Information)

![Omni Houston Hotel](https://images.trvl-media.com/lodging/1000000/20000/17800/17746/37423ee4_y.jpg)

### Omni Houston Hotel

10/10 Excellent

"Pleasant location, spotless room, great view if you get the lake facing side."

[](https://expedia.ca/Houston-Hotels-Omni-Houston-Hotel.h17746.Hotel-Information)

![Hilton Houston Plaza/Medical Center](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/294f3d50_y.jpg)

### Hilton Houston Plaza/Medical Center

10/10 Excellent

"Clean room"

[](https://expedia.ca/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information)

![The Whitehall Houston](https://images.trvl-media.com/lodging/1000000/700000/693700/693655/f1d85056_y.jpg)

### The Whitehall Houston

10/10 Excellent

"Great friendly staff who went above and beyond to accommodate me. I arrived at the property at 1:00 pm and even though my check-in time was at 3:00, they offered to check me in 2 hours early without any hesitation. They knew I was running the Houston marathon on my return date and assured me that they will accommodate an hour for a late checkout. Very professional staff and attentive to guest’s needs. Highly recommend The Whitehall Houston!! "

[](https://expedia.ca/Houston-Hotels-The-Whitehall-Houston.h693655.Hotel-Information)

## Frequently asked questions

### What are the best hotels in South Main that travellers recommend?

> For families, [Wingate Houston near NRG Park/Medical Center](https://www.expedia.ca/Houston-Hotels-Wingate-By-Wyndham-Houston-Reliant-Medical-Center.h66022895.Hotel-Information) is another great option. With a complimentary continental breakfast to fuel your adventures and a refreshing outdoor pool, it caters superbly to parents and kids alike. The accessible fitness centre allows for some family fun, while the hotel's pet-friendly policies make it a fantastic choice for those traveling with furry companions. With a focus on convenience and value, this hotel provides excellent amenities while keeping everyone comfortable.

### What are the best family hotels in South Main?

> Another excellent option is the [Candlewood Suites Houston Medical Center by IHG](https://www.expedia.ca/Houston-Hotels-Candlewood-Suites-Houston-Medical-Center.h2227000.Hotel-Information), which boasts a family-friendly atmosphere with its free cribs, connecting rooms, and a sofa bed, making it great for families needing extra space. Guests appreciate the convenience of in-room kitchen amenities like a microwave and dishwasher, allowing for easy meal prep during your stay. It has a review score of 7.6, reflecting its appeal to families on the go.
> 
>   
> For those seeking a place with a pool, the [Quality Inn & Suites NRG Park - Medical Center](https://www.expedia.ca/Houston-Hotels-Quality-Inn-Suites-NRG-Park-Medical-Center.h17531.Hotel-Information) is a great choice. With its inviting pool area, free meals for children, and options for rollaway beds at no extra charge, families can enjoy a splash-filled vacation while also benefiting from daily housekeeping and snack options.
> 
>   
> Lastly, the [Wyndham Houston near NRG Park/Medical Center](https://www.expedia.ca/Houston-Hotels-Wyndham-Houston-Near-NRG-ParkMedical-Center.h21297.Hotel-Information) features child-friendly window designs and connecting rooms, catering specifically to families' needs. The presence of kitchenettes adds to the convenience, allowing families to prepare snacks or meals together. This property has a traveller rating of 7.2, making it a reliable choice for family stays.
> 
>   
> These hotels exemplify quality and convenience, ensuring that your family's adventure in South Main is both enjoyable and comfortable.

### What hotels in South Main offer free breakfast?

> Another great choice is [Quality Inn & Suites NRG Park - Medical Center](https://www.expedia.ca/Houston-Hotels-Quality-Inn-Suites-NRG-Park-Medical-Center.h17531.Hotel-Information), which also provides a free breakfast, including options for those on the go. This family-friendly hotel offers spacious suites with balconies and patios, allowing families to unwind outdoors. The outdoor pool invites guests to relax and enjoy the Texas sunshine, while the complimentary area shuttle makes it simple to explore the attractions nearby.
> 
>   
> For those traveling without children, the [Wingate Houston near NRG Park/Medical Center](https://www.expedia.ca/Houston-Hotels-Wingate-By-Wyndham-Houston-Reliant-Medical-Center.h66022895.Hotel-Information) presents a delightful blend of comfort and accessibility. With an outdoor pool and fitness centre, it caters to adults looking for a rejuvenating getaway. The hotel's continental breakfast is another perk that guarantees a satisfying start to your morning adventures.

### What are the best budget hotels in South Main?

> For another appealing choice, [Candlewood Suites Houston Medical Center by IHG](https://www.expedia.ca/Houston-Hotels-Candlewood-Suites-Houston-Medical-Center.h2227000.Hotel-Information) stands out with a review score of 7.6\. This property is superb for families, as it features kitchenettes in the rooms, allowing for meal preparation and snacks on the go. Kids can also enjoy the complimentary cribs and sofa beds, making it a comfortable stay for everyone. Additionally, the hotel offers a free area shuttle, which is great for exploring local attractions without the hassle of driving.
> 
>   
> If you're traveling with your partner or friends, the [Wyndham Houston near NRG Park/Medical Center](https://www.expedia.ca/Houston-Hotels-Wyndham-Houston-Near-NRG-ParkMedical-Center.h21297.Hotel-Information) offers a more relaxed atmosphere with a lower review score of 7.2\. This hotel features outdoor pool access and convenient amenities, including a kitchenette in some rooms, which can appeal to those looking for a home-like experience while away.
> 
>   
> No matter your travel group, these options in South Main cater to various needs while ensuring a comfortable and enjoyable stay.

### Can I cancel my hotel reservation on Expedia?

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- [Casino Hotels in Astrodome ](https://www.expedia.ca/Astrodome-Houston-Hotels-Casino-Hotel.0-n553248635976007975-0-tCasinoHotel.Travel-Guide-Filter-Hotels)
- [Cheap Hotels in Astrodome ](https://www.expedia.ca/Astrodome-Houston-Hotels-Cheap-Hotels.0-n553248635976007975-0-tCheapHotels.Travel-Guide-Filter-Hotels)
- [Luxury Hotels in Astrodome ](https://www.expedia.ca/Astrodome-Houston-Hotels-Luxury-Hotel.0-n553248635976007975-0-tLuxuryHotel.Travel-Guide-Filter-Hotels)
- [Spa Hotels in Astrodome ](https://www.expedia.ca/Astrodome-Houston-Hotels-Spa-Hotel.0-n553248635976007975-0-tSpaHotel.Travel-Guide-Filter-Hotels)
- [Astrodome Hotels ](https://www.expedia.ca/Astrodome-Houston-Hotels.0-n553248635976007975-0.Travel-Guide-Filter-Hotels)
- [Hotels near Aveva Stadium ](https://www.expedia.ca/Aveva-Stadium-Hotels.0-l676706154760683520-0.Travel-Guide-Filter-Hotels)
- [Bellaire Hotels ](https://www.expedia.ca/Bellaire-Hotels.d78408.Travel-Guide-Hotels)
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- [Hotels & Resorts for Couples in Braeswood Place ](https://www.expedia.ca/Braeswood-Place-Houston-Hotels-Couples-Resorts-Hotels.0-n553248635976387047-0-tCouplesResortsHotels.Travel-Guide-Filter-Hotels)
- [Hotels with a Pool in Braeswood Place ](https://www.expedia.ca/Braeswood-Place-Houston-Hotels-Hotel-With-Pool.0-n553248635976387047-0-tHotelwithPool.Travel-Guide-Filter-Hotels)
- [Braeswood Place Hotels ](https://www.expedia.ca/Braeswood-Place-Houston-Hotels.0-n553248635976387047-0.Travel-Guide-Filter-Hotels)
- [B&B in Dryden/TMC Station ](https://www.expedia.ca/DrydenTMC-Station-Bed-And-Breakfast.d6211670-aaBedAndBreakfast.Travel-Guide-Accommodation)
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- [Hotels near Fannin South Station ](https://www.expedia.ca/Fannin-South-Station-Hotels.d6211683.Travel-Guide-Hotels)
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- [Hotels near NRG Arena ](https://www.expedia.ca/NRG-Arena-Hotels.0-l553248635975094722-0.Travel-Guide-Filter-Hotels)
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- [Luxury Hotels in Rice Village ](https://www.expedia.ca/Rice-Village-Houston-Hotels-Luxury-Hotel.0-n869686528136192000-0-tLuxuryHotel.Travel-Guide-Filter-Hotels)
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- [Hotels with a Pool in Southside Place ](https://www.expedia.ca/Southside-Place-Houston-Hotels-Hotel-With-Pool.0-n160529-0-tHotelwithPool.Travel-Guide-Filter-Hotels)
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- [Apartments in Southwest Houston ](https://www.expedia.ca/Southwest-Houston-Apartments.d6189441-aaApartments.Travel-Guide-Accommodation)
- [Condo Rentals in Southwest Houston ](https://www.expedia.ca/Southwest-Houston-Condos.d6189441-aaCondos.Travel-Guide-Accommodation)
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- [Beach Hotel Hotels in Southwest Houston ](https://www.expedia.ca/Southwest-Houston-Hotels-Beach-Hotel.0-0-d6189441-tBeachHotel.Travel-Guide-Filter-Hotels)
- [Casino Hotels in Southwest Houston ](https://www.expedia.ca/Southwest-Houston-Hotels-Casino-Hotel.0-0-d6189441-tCasinoHotel.Travel-Guide-Filter-Hotels)
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- [Southwest Houston Hotels ](https://www.expedia.ca/Southwest-Houston-Hotels.d6189441.Travel-Guide-Hotels)
- [Aparthotels in Stadium Park/Astrodome Station ](https://www.expedia.ca/Stadium-ParkAstrodome-Station-Apart-Hotels.d6211680-aaApartHotels.Travel-Guide-Accommodation)
- [Hostels in Stadium Park/Astrodome Station ](https://www.expedia.ca/Stadium-ParkAstrodome-Station-Hostels.d6211680-aaHostels.Travel-Guide-Accommodation)
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- [Farmstay in TMC Transit Center ](https://www.expedia.ca/TMC-Transit-Center-Agritourism.d6211673-aaAgritourism.Travel-Guide-Accommodation)
- [Hotels near Texas Children's Hospital ](https://www.expedia.ca/Texas-Childrens-Hospital-Hotels.0-l553248635389801905-0.Travel-Guide-Filter-Hotels)
- [Cheap Hotels in Texas Medical Center ](https://www.expedia.ca/Texas-Medical-Center-Houston-Hotels-Cheap-Hotels.0-n6143504-0-tCheapHotels.Travel-Guide-Filter-Hotels)
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- [Flights to Houston ](https://www.expedia.ca/Cheap-Flights-To-Houston.d178265.Travel-Guide-Flights)
- [Flights to Southwest Houston ](https://www.expedia.ca/Cheap-Flights-To-Southwest-Houston.d6189441.Travel-Guide-Flights)
- [Flights from Amsterdam to Southwest Houston ](https://www.expedia.ca/lp/flights/178229/6189441/amsterdam-to-southwest-houston)
- [Flights from Atlanta to Southwest Houston ](https://www.expedia.ca/lp/flights/178232/6189441/atlanta-to-southwest-houston)
- [Flights from Auckland to Southwest Houston ](https://www.expedia.ca/lp/flights/178233/6189441/auckland-to-southwest-houston)
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- [Flights from Bogotá to Southwest Houston ](https://www.expedia.ca/lp/flights/178238/6189441/bogota-to-southwest-houston)
- [Flights from Calgary to Southwest Houston ](https://www.expedia.ca/lp/flights/178245/6189441/calgary-to-southwest-houston)
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- [Flights from St. Louis to Southwest Houston ](https://www.expedia.ca/lp/flights/178309/6189441/st-louis-to-southwest-houston)
- [Flights from Richmond to Southwest Houston ](https://www.expedia.ca/lp/flights/601761/6189441/richmond-to-southwest-houston)

- [Visit Astrodome ](https://www.expedia.ca/Houston-Astrodome.dx553248635976007975)
- [Visit Southside Place ](https://www.expedia.ca/Houston-Southside-Place.dx160529)
- [Visit Texas Medical Center ](https://www.expedia.ca/Houston-Texas-Medical-Center.dx6143504)
- [Md Anderson Cancer Center ](https://www.expedia.ca/MD-Anderson-Cancer-Center-Texas-Medical-Center.d6248539.Vacation-Attraction)
- [Nrg Stadium ](https://www.expedia.ca/NRG-Stadium-Astrodome.d553248635929331916.Vacation-Attraction)
- [Visit Southwest Houston ](https://www.expedia.ca/Southwest-Houston.dx6189441)

- [Airport Van Rental Rental Cars in Southwest Houston ](https://www.expedia.ca/Airport-Van-Rental-Car-Rentals-In-Southwest-Houston.d6189441-c1092.Car-Rental-Guide-Suppliers)
- [Alamo Rent A Car Rental Cars in Southwest Houston ](https://www.expedia.ca/Alamo-Rent-A-Car-Car-Rentals-In-Southwest-Houston.d6189441-c6.Car-Rental-Guide-Suppliers)
- [Auto Rent Rental Cars in Southwest Houston ](https://www.expedia.ca/Auto-Rent-Car-Rentals-In-Southwest-Houston.d6189441-c1006.Car-Rental-Guide-Suppliers)
- [Budget Rental Cars in Southwest Houston ](https://www.expedia.ca/Budget-Car-Rentals-In-Southwest-Houston.d6189441-c39.Car-Rental-Guide-Suppliers)
- [Discount Quebec Rental Cars in Southwest Houston ](https://www.expedia.ca/Discount-Quebec-Car-Rentals-In-Southwest-Houston.d6189441-c1137.Car-Rental-Guide-Suppliers)
- [Global Rent a Car Rental Cars in Southwest Houston ](https://www.expedia.ca/Global-Rent-A-Car-Car-Rentals-In-Southwest-Houston.d6189441-c1062.Car-Rental-Guide-Suppliers)
- [Goldcar Key’n Go Rental Cars in Southwest Houston ](https://www.expedia.ca/Goldcar-Keyn-Go-Car-Rentals-In-Southwest-Houston.d6189441-c1044.Car-Rental-Guide-Suppliers)
- [Hertz Rental Cars in Southwest Houston ](https://www.expedia.ca/Hertz-Car-Rentals-In-Southwest-Houston.d6189441-c40.Car-Rental-Guide-Suppliers)
- [Localiza Rental Cars in Southwest Houston ](https://www.expedia.ca/Localiza-Car-Rentals-In-Southwest-Houston.d6189441-c1063.Car-Rental-Guide-Suppliers)
- [Locauto Rental Cars in Southwest Houston ](https://www.expedia.ca/Locauto-Car-Rentals-In-Southwest-Houston.d6189441-c1140.Car-Rental-Guide-Suppliers)
- [Nextcar Rental Cars in Southwest Houston ](https://www.expedia.ca/Nextcar-Car-Rentals-In-Southwest-Houston.d6189441-c1061.Car-Rental-Guide-Suppliers)
- [Rent A Wreck Rental Cars in Southwest Houston ](https://www.expedia.ca/Rent-A-Wreck-Car-Rentals-In-Southwest-Houston.d6189441-c33.Car-Rental-Guide-Suppliers)

- [Things to do in Southwest Houston ](https://www.expedia.ca/Things-To-Do-In-Southwest-Houston.d6189441.Travel-Guide-Activities)

- [Book Hotels in South Main on Expedia.com ](https://www.expedia.com/South-Main-Houston-Hotels.0-n553248635976386992-0.Travel-Guide-Filter-Hotels)