A calm lake with mountains in the background.

Seneca Vacation Rentals

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Check prices for these dates

In two weeks
Sep 18 - Sep 20
In two months
Oct 30 - Nov 1
In three months
Nov 27 - Nov 29
In four months
Dec 25 - Dec 27

Our top choices for Seneca vacation homes

A spacious living room with leather sofas, a wooden coffee table, a TV stand, and a ceiling fan.

1. Walk to Boat Ramp Lake Keowee w/ Parking + Firepit

Walk to Boat Ramp Lake Keowee w/ Parking + Firepit
Seneca
The price is CA $201
CA $560 total
includes taxes & fees
Sep 9 - Sep 10
Walk to Boat Ramp Lake Keowee w/ Parking + Firepit
A dining area with a wooden table, chairs, and a hanging light fixture.

2. Iroquois Crossroads - 10 min from Clemson & lakes

Iroquois Crossroads - 10 min from Clemson & lakes
Seneca
The price is CA $162
CA $464 total
includes taxes & fees
Sep 23 - Sep 24
Iroquois Crossroads - 10 min from Clemson & lakes
A living room with a large tiger mural, a fireplace, a sofa, and a coffee table.

3. Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!

Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!
Downtown
10.0 out of 10, Exceptional, (21 reviews)
"Great host! We had a great experience during our stay. "
United States
David E.
The price is CA $237
CA $528 total
includes taxes & fees
Sep 9 - Sep 10
Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!
A two-story house with a covered patio area, a small shed, and a large tree in the background.

4. Renovated 3BR near Lake Keowee & Clemson

Renovated 3BR near Lake Keowee & Clemson
Seneca
10.0 out of 10, Exceptional, (2 reviews)
"Fantastic location and really nicely done home. It was a perfect touch having a desk in one of the rooms to be able to get work done."
United States
Brenda B.
The price is CA $204
CA $464 total
includes taxes & fees
Sep 9 - Sep 10
Renovated 3BR near Lake Keowee & Clemson
A spacious living room with a sofa, chairs, a wooden coffee table, and a fireplace.

5. Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock

Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock
Seneca
8.0 out of 10, Very good, (7 reviews)
"Adorable and clean house! The yard is beautiful "
United States
Diana H.
The price is CA $228
CA $407 total
includes taxes & fees
Sep 27 - Sep 28
Lake Retreat- Mins to CU- Kayaks, Fire Pit, Dock
A modern kitchen with a central island, wooden cabinets, and a built-in refrigerator.

6. 3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson

3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson
Seneca
9.8 out of 10, Exceptional, (12 reviews)
"Easy check in, pet-friendly, great location!!"
United States
Jason M.
The price is CA $293
CA $505 total
includes taxes & fees
Sep 4 - Sep 5
3 bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson
A wooden deck with a railing overlooking a forested area during sunset.

7. Waterfront 3br home on Lake Hartwell near Clemson

Waterfront 3br home on Lake Hartwell near Clemson
Seneca
9.8 out of 10, Exceptional, (15 reviews)
"We enjoyed our stay. Had everything we needed. "
United States
Diane S.
The price is CA $339
CA $731 total
includes taxes & fees
Sep 7 - Sep 8
Waterfront 3br home on Lake Hartwell near Clemson
A modern kitchen with white cabinetry, a central island, and a large window.

8. The Big Golf House- 10 miles to Clemson

The Big Golf House- 10 miles to Clemson
Seneca
10.0 out of 10, Exceptional, (4 reviews)
"Great house and host!"
United States
David E.
The price is CA $374
CA $865 total
includes taxes & fees
Sep 22 - Sep 23
The Big Golf House- 10 miles to Clemson
A bedroom with a bed, bench, bedside table, and a view of a lake.

9. Johnsons Cove - Lakefront Retreat With EV Charger

Johnsons Cove - Lakefront Retreat With EV Charger
Seneca
10.0 out of 10, Exceptional, (1 review)
"We truly enjoyed our stay at Johnson’s Cove. The property was super clean. The kitchen was one of the best stocked rentals I have stayed in. The mattress we slept on was better than our mattress at home. The communication with the owner was fast and she was quick to respond. We rented a pontoon for the day and the dock was easy to use for loading and unloading/restroom. We will surely rent there again."
United States
Rebecca G.
The price is CA $457
CA $1,058 total
includes taxes & fees
Sep 8 - Sep 9
Johnsons Cove - Lakefront Retreat With EV Charger
A covered porch with wicker furniture, a wooden table, and a ceiling fan.

10. Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium

Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium
Seneca
9.6 out of 10, Exceptional, (11 reviews)
"Everything was lovely."
United States
Allison C.
The price is CA $452
CA $947 total
includes taxes & fees
Sep 9 - Sep 10
Beautiful Updated Clemson Lake House - 4 Miles from Downtown Clemson and the Stadium
A deck with two Adirondack chairs overlooking a lake and a grassy area.

11. Family Retreat on South Cove of Lake Keowee; Private Dock; ~ 10 Mi from Clemson

Family Retreat on South Cove of Lake Keowee; Private Dock; ~ 10 Mi from Clemson
Seneca
10.0 out of 10, Exceptional, (24 reviews)
"Great home and host"
United States
Anonymous traveller
The price is CA $969
CA $2,001 total
includes taxes & fees
Sep 13 - Sep 14
Family Retreat on South Cove of Lake Keowee; Private Dock; ~ 10 Mi from Clemson
A cozy living room with a fireplace, a dining area with a table and chairs, and a kitchen in the background.

12. Clemson Memorabilia House Frank Howard III’s Home

Clemson Memorabilia House Frank Howard III’s Home
Clemson
8.4 out of 10, Very good, (20 reviews)
"Great location!"
United States
Libby S.
The price is CA $117
CA $369 total
includes taxes & fees
Sep 15 - Sep 16
Clemson Memorabilia House Frank Howard III’s Home
A church interior with pews, a cross, and a view of a landscape through a large window.

13. The Rustic Rectangle

The Rustic Rectangle
Pendleton
10.0 out of 10, Exceptional, (12 reviews)
"Great fun experiencing a shipping container conversion!"
United States
Mary Ellen V.
The price is CA $135
CA $335 total
includes taxes & fees
Sep 8 - Sep 9
The Rustic Rectangle
A kitchen with white cabinets, a stainless steel refrigerator, and a countertop with a flower arrangement and a bag.

14. Large 3 Bedroom Townhome Downtown Clemson and garage! Walk to Clemson Stadium!

Large 3 Bedroom Townhome Downtown Clemson and garage! Walk to Clemson Stadium!
Clemson
The price is CA $271
CA $667 total
includes taxes & fees
Sep 29 - Sep 30
Large 3 Bedroom Townhome Downtown Clemson and garage! Walk to Clemson Stadium!
A two-story house with a balcony, surrounded by trees and a body of water.

15. Lake Keowee Home w Dock, Kayaks, Hot Tub!

Lake Keowee Home w Dock, Kayaks, Hot Tub!
West Union
9.8 out of 10, Exceptional, (6 reviews)
"Great space! We had a wonderful time!! "
United States
Kelly
The price is CA $446
CA $997 total
includes taxes & fees
Sep 13 - Sep 14
Lake Keowee Home w Dock, Kayaks, Hot Tub!
An aerial view of a marina with multiple docks, a swimming pool, and a building with a dock extending into the water.

16. Resort Pool & Spa 3BR 3BTH w Loft, Family Gameroom

Resort Pool & Spa 3BR 3BTH w Loft, Family Gameroom
Salem
9.8 out of 10, Exceptional, (58 reviews)
"Awesome property for stay in the Keowee Key community. "
United States
John G.
Resort Pool & Spa 3BR 3BTH w Loft, Family Gameroom
A wooden deck with a round table and chairs, overlooking a lake.

17. Lake Hartwell Covered Dock & Sunset Beach 3BD, 1BA

Lake Hartwell Covered Dock & Sunset Beach 3BD, 1BA
Fair Play
9.6 out of 10, Exceptional, (62 reviews)
"The cottage was very nice. Great view of the water. super easy walk to the water. Dock & kayaks were enjoyed. "
United States
Steve A.
Lake Hartwell Covered Dock & Sunset Beach 3BD, 1BA
A modern kitchen with a dining area, wooden flooring, and a ceiling fan.

18. Our Nest, a well loved quiet retreat in Foxwood Hills Resort near Lake Hartwell.

Our Nest, a well loved quiet retreat in Foxwood Hills Resort near Lake Hartwell.
Westminster
9.8 out of 10, Exceptional, (10 reviews)
"Outstanding place and host. Will definitely stay here again. "
United States
William H. J.
The price is CA $146
CA $334 total
includes taxes & fees
Sep 15 - Sep 16
Our Nest, a well loved quiet retreat in Foxwood Hills Resort near Lake Hartwell.
A spacious dining area with a wooden table and chairs, a fireplace, and large windows offering a view of the outdoors.

19. Lake Hartwell Frank Howard Home Clemson

Lake Hartwell Frank Howard Home Clemson
4.0 star property
Anderson
The price is CA $256
CA $515 total
includes taxes & fees
Sep 20 - Sep 21
Lake Hartwell Frank Howard Home Clemson
A two-story house with a balcony, wooden deck, and string lights.

20. Clemson|SUPs|ParkPass|PizzaOven|PortmanMarina|EV

Clemson|SUPs|ParkPass|PizzaOven|PortmanMarina|EV
Anderson
10.0 out of 10, Exceptional, (12 reviews)
"Beautifully decorated and updated condo. It was so private it felt like a single home. Very thoughtful details throughout from the decor to the house supplies. We stayed to move my daughter into Clemson so didn’t take advantage of the lake or boards but there is a nice outdoor deck and even a fire pit. Very comfy vibe! About 15 to 20 minutes from campus, easy to get around."
United States
Diana
The price is CA $199
CA $649 total
includes taxes & fees
Sep 9 - Sep 10
Clemson|SUPs|ParkPass|PizzaOven|PortmanMarina|EV
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Seneca Hotel Reviews

4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit, Pet Friendly!

4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit, Pet Friendly!

10/10 Excellent
"We had an incredible trip to this property and enjoyed all the amenities! The view of the lake is spectacular, there was one ry of room for our family and friends that came to visit. The kitchen has everything you could need. The kayaks were a hit and so was football and ping pong. We felt at home for the week we stayed and the hosts are amazing! Highly recommend!"
Mindy R. 7-night trip
Posted 1 day ago
4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit, Pet Friendly!

Find out more about Seneca

Seneca Vacation Homes information

Number of reviews
188
Accommodation
754 Vacation Homes
Lowest Price
CA $334
Highest Price
CA $2,001

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