Title: São Tomé and Príncipe Villas from CA $423 | Expedia.ca

[São Tomé and Príncipe Travel Guide](https://expedia.ca/Sao-Tome-And-Principe.dx156)[São Tomé and Príncipe Hotels](https://expedia.ca/Destinations-In-Sao-Tome-And-Principe.d156.Hotel-Destinations)[Vacation Rentals in São Tomé and Príncipe](https://expedia.ca/Destinations-In-Sao-Tome-And-Principe.d156.Vacation-Rental-Destinations)[São Tomé and Príncipe Flights](https://expedia.ca/Destinations-In-Sao-Tome-And-Principe.d156.Flight-Destinations)[São Tomé and Príncipe Car Rentals](https://expedia.ca/Destinations-In-Sao-Tome-And-Principe.d156.Car-Rental-Destinations)[São Tomé and Príncipe Vacations](https://expedia.ca/Sao-Tome-And-Principe.d156.Destination-Travel-Guides)

![!](https://images.trvl-media.com/place/6049290/38d2db01-8e64-464a-afac-dfbf1c85603e.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Sebastião Mesquita e Carmo

![](https://images.trvl-media.com/place/6049290/38d2db01-8e64-464a-afac-dfbf1c85603e.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=156&startDate=2026-02-06&endDate=2026-02-08&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=156&startDate=2026-03-20&endDate=2026-03-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[Apr 17 - Apr 19](https://www.expedia.ca/Hotel-Search?regionId=156&startDate=2026-04-17&endDate=2026-04-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[May 15 - May 17](https://www.expedia.ca/Hotel-Search?regionId=156&startDate=2026-05-15&endDate=2026-05-17&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for São Tomé and Príncipe villas

![Outdoor dining](https://images.trvl-media.com/lodging/111000000/110860000/110857500/110857426/c7a66438.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/111000000/110860000/110857500/110857426/51847ac2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/111000000/110860000/110857500/110857426/ec3dd4e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach](https://images.trvl-media.com/lodging/111000000/110860000/110857500/110857426/622f9ead.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Villa in Santana

[](https://www.expedia.ca/Santana-Hotels-Sea-House.h110857426.Hotel-Information)

CA $331

CA $423 total

includes taxes & fees

Feb 7 - Feb 8

[](https://www.expedia.ca/Santana-Hotels-Sea-House.h110857426.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/105000000/104870000/104860500/104860433/bac286e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/105000000/104870000/104860500/104860433/ec0d3979.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/105000000/104870000/104860500/104860433/3ededc18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/105000000/104870000/104860500/104860433/7d03eeb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Villa in São Tomé

[](https://www.expedia.ca/Sao-Tome-Island-Hotels-Villa-Familial-A-Sao-Tome-A-Moins-De-5-Minutes-De-Laeroport-Et-Du-Centre-Ville.h104860433.Hotel-Information)

[](https://www.expedia.ca/Sao-Tome-Island-Hotels-Villa-Familial-A-Sao-Tome-A-Moins-De-5-Minutes-De-Laeroport-Et-Du-Centre-Ville.h104860433.Hotel-Information)

![Villa | Property grounds](https://images.trvl-media.com/lodging/94000000/93040000/93032900/93032898/9798854c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Villa | Living area](https://images.trvl-media.com/lodging/94000000/93040000/93032900/93032898/80124555.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Villa | Pool](https://images.trvl-media.com/lodging/94000000/93040000/93032900/93032898/63ec7933.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Villa | Interior](https://images.trvl-media.com/lodging/94000000/93040000/93032900/93032898/f9d5742c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Villa in Santana

[](https://www.expedia.ca/Sao-Tome-Island-Hotels-Pool-And-Beach-Villa-In-Santana.h93032898.Hotel-Information)

[](https://www.expedia.ca/Sao-Tome-Island-Hotels-Pool-And-Beach-Villa-In-Santana.h93032898.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-03&endDate=2026-02-04&regionId=156&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

## Find vacation rentals that suit your style

Villas

[](https://www.expedia.ca/Hotel-Search?destination=S%C3%A3o+Tom%C3%A9+and+Pr%C3%ADncipe&regionId=156&latLong=0.18636%2C6.613081&adults=2&startDate=2026-04-19&d1=2026-04-19&endDate=2026-04-22&d2=2026-04-22&lodging=VILLA)

Private vacation homes

[](https://www.expedia.ca/Hotel-Search?destination=S%C3%A3o+Tom%C3%A9+and+Pr%C3%ADncipe&regionId=156&latLong=0.18636%2C6.613081&adults=2&startDate=2026-04-19&d1=2026-04-19&endDate=2026-04-22&d2=2026-04-22&lodging=VACATION_HOME)

Chalets

[](https://www.expedia.ca/Hotel-Search?destination=S%C3%A3o+Tom%C3%A9+and+Pr%C3%ADncipe&regionId=156&latLong=0.18636%2C6.613081&adults=2&startDate=2026-04-19&d1=2026-04-19&endDate=2026-04-22&d2=2026-04-22&lodging=CHALET)

Apartments

[](https://www.expedia.ca/Hotel-Search?destination=S%C3%A3o+Tom%C3%A9+and+Pr%C3%ADncipe&regionId=156&latLong=0.18636%2C6.613081&adults=2&startDate=2026-04-19&d1=2026-04-19&endDate=2026-04-22&d2=2026-04-22&lodging=APARTMENT)

Cabins

[](https://www.expedia.ca/Hotel-Search?destination=S%C3%A3o+Tom%C3%A9+and+Pr%C3%ADncipe&regionId=156&latLong=0.18636%2C6.613081&adults=2&startDate=2026-04-19&d1=2026-04-19&endDate=2026-04-22&d2=2026-04-22&lodging=CABIN)

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## Top São Tomé and Príncipe Hotel Reviews

## Find out more about São Tomé and Príncipe

## São Tomé and Príncipe Villas information

| Number of reviews |          |
| ----------------- | -------- |
| Accommodation     | 3 Villas |
| Lowest Price      | CA $423  |
| Highest Price     | CA $423  |

## Frequently asked questions

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