Title: Book the Best Santiago LUXURY Hotels - Upscale Hotels in Santiago | Expedia.ca

  

[Santiago Travel Guide](https://expedia.ca/Santiago.dx6085194)[Hotels in Santiago](https://expedia.ca/Santiago-Hotels.d6085194.Travel-Guide-Hotels)[Vacation Rentals in Santiago](https://expedia.ca/Santiago-Vacation-Rentals.d6085194.Travel-Guide-VacationRentals)[Flights to Santiago](https://expedia.ca/Cheap-Flights-To-Santiago.d6085194.Travel-Guide-Flights)[Santiago Car Rentals](https://expedia.ca/Car-Rentals-In-Santiago.d6085194.Car-Rental-Guide)[Santiago Vacation Packages](https://expedia.ca/Santiago.d6085194.Destination-Travel-Guides)

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# Find luxury hotels in Santiago

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## Check availability on Santiago Luxury Hotels

Tonight

[Oct 14 - Oct 15](https://www.expedia.ca/Hotel-Search?regionId=6085194&startDate=2025-10-14&endDate=2025-10-15&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Oct 15 - Oct 16](https://www.expedia.ca/Hotel-Search?regionId=6085194&startDate=2025-10-15&endDate=2025-10-16&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6085194&startDate=2025-10-17&endDate=2025-10-19&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6085194&startDate=2025-10-24&endDate=2025-10-26&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Top Santiago Luxury Hotels

## Top Santiago Hotel Reviews

## Explore a world of travel with Expedia

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