Title: Book The Best Hotels in Santiago del Río for 2025 from CA $42 - Competitive Prices - Expedia.ca [Santiago del Río Travel Guide](https://expedia.ca/Santiago-Del-Rio.dx553248635640665145)[Vacation Rentals in Santiago del Río](https://expedia.ca/Santiago-Del-Rio-Vacation-Rentals.d553248635640665145.Travel-Guide-VacationRentals)[Santiago del Río Car Rentals](https://expedia.ca/Car-Rentals-In-Santiago-Del-Rio.d553248635640665145.Car-Rental-Guide)[Santiago del Río Vacation Packages](https://expedia.ca/Santiago-Del-Rio.d553248635640665145.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Santiago del Río from CA $42 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Nov 17 - Nov 18](https://www.expedia.ca/Hotel-Search?regionId=553248635640665145&startDate=2025-11-17&endDate=2025-11-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 18 - Nov 19](https://www.expedia.ca/Hotel-Search?regionId=553248635640665145&startDate=2025-11-18&endDate=2025-11-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=553248635640665145&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=553248635640665145&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 2,543 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSantiago-Del-Rio-Hotels.d553248635640665145.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSantiago-Del-Rio-Hotels.d553248635640665145.Travel-Guide-Hotels) ## More cheap stays in Santiago del Río ![HOTEL POSADA DON MATIAS](https://images.trvl-media.com/lodging/110000000/109630000/109623100/109623058/cd4c38fa_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### HOTEL POSADA DON MATIAS 316 C. de Ignacio Aldama Centro Oaxaca OAX CA $35 CA $42 total Nov 21 - Nov 22 includes taxes & fees 9.2/10 Wonderful! (165 reviews) [](https://expedia.ca/Oaxaca-Hotels-HOTEL-POSADA-DON-MATIAS.h109623058.Hotel-Information) ![Casona Oaxaca Historia y Paz](https://images.trvl-media.com/lodging/108000000/107620000/107611700/107611619/49b3b44d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Casona Oaxaca Historia y Paz Trujano 206 Oaxaca Oax. CA $107 CA $127 total Nov 26 - Nov 27 includes taxes & fees 9.2/10 Wonderful! (152 reviews) [](https://expedia.ca/Oaxaca-Hotels-Casona-Oaxaca-Historia-Y-Paz.h107611619.Hotel-Information) ![Blater Hotel](https://images.trvl-media.com/lodging/16000000/15260000/15251800/15251774/a74d6916_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Blater Hotel Calle Del Morro S/N Col. Santa Maria Santa Maria Colotepec Oaxaca CA $116 CA $138 total Dec 8 - Dec 9 includes taxes & fees 9.2/10 Wonderful! (41 reviews) [](https://expedia.ca/Santa-Maria-Colotepec-Hotels-Blater-Hotel.h15251774.Hotel-Information) ![HOTEL BIULÚ](https://images.trvl-media.com/lodging/91000000/90950000/90946300/90946251/7f6d4e14_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### HOTEL BIULÚ BOULEVARD BENITO JUAREZ, 22 Santa María Huatulco OAX CA $100 CA $119 total Nov 19 - Nov 20 includes taxes & fees 8.8/10 Excellent! (130 reviews) [](https://expedia.ca/Santa-Maria-Huatulco-Hotels-HOTEL-BIULU.h90946251.Hotel-Information) ![Happy Express Hotel](https://images.trvl-media.com/lodging/10000000/9590000/9587300/9587247/820d5b66_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Happy Express Hotel Diaz Ordaz 312 Oaxaca OAX CA $62 CA $74 total Nov 19 - Nov 20 includes taxes & fees 9/10 Wonderful! (307 reviews) [](https://expedia.ca/Oaxaca-Hotels-Happy-Express-Hotel.h9587247.Hotel-Information) ![Hotel Posada El Cid](https://images.trvl-media.com/lodging/12000000/11600000/11592000/11591984/05e73c87_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Posada El Cid Pino Suarez 903, Colonia Centro Oaxaca OAX CA $59 CA $70 total Nov 19 - Nov 20 includes taxes & fees 7.8/10 Good! (66 reviews) [](https://expedia.ca/Oaxaca-Hotels-Posada-Del-Cid.h11591984.Hotel-Information) ## Frequently asked questions ### If I need to cancel my hotel reservation in Santiago del Río, will I receive a refund? > Yes, most hotel reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it might still be possible to cancel it and get a refund within 24 hours of your booking. Filter your search by [fully refundable](https://www.expedia.ca/Hotel-Search?regionId=553248635640665145&paymentType=FREE_CANCELLATION) to find flexible hotel deals in Santiago del Río. ### What's the weather like in Santiago del Río? > The hottest months are usually April and May with an average temp of 67°F, while the coldest months are January and December with an average of 60°F. The rainiest months in Santiago del Río are September, August, June, and July, with each month seeing an average of 12 inches of rainfall. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [3 Star Hotels in San Juan Bautista Cuicatlán](https://www.expedia.ca/3Star-San-Juan-Bautista-Cuicatlan-Hotels.s30-0-d553248635640632624.Travel-Guide-Filter-Hotels) - [Asunción Nochixtlán Hotels](https://www.expedia.ca/Asuncion-Nochixtlan-Hotels.d6299360.Travel-Guide-Hotels) - [Calihualá Hotels](https://www.expedia.ca/Calihuala-Hotels.d553248635640632815.Travel-Guide-Hotels) - [Chalcatongo de Hidalgo Hotels](https://www.expedia.ca/Chalcatongo-De-Hidalgo-Hotels.d553248635640677829.Travel-Guide-Hotels) - [Huajuapan Hotels](https://www.expedia.ca/Huajuapan-Hotels.d6245105.Travel-Guide-Hotels) - [Ixpantepec Nieves Hotels](https://www.expedia.ca/Ixpantepec-Nieves-Hotels.d553248635640640405.Travel-Guide-Hotels) - [Mariscala de Juárez Hotels](https://www.expedia.ca/Mariscala-De-Juarez-Hotels.d553248635640704411.Travel-Guide-Hotels) - [Putla Villa de Guerrero Hotels](https://www.expedia.ca/Putla-Villa-De-Guerrero-Hotels.d553248635640677765.Travel-Guide-Hotels) - [San Jorge Nuchita Hotels](https://www.expedia.ca/San-Jorge-Nuchita-Hotels.d553248635640681158.Travel-Guide-Hotels) - [San Juan Bautista Tlachichilco Hotels](https://www.expedia.ca/San-Juan-Bautista-Tlachichilco-Hotels.d553248635640658855.Travel-Guide-Hotels) - [San Juan Cacahuatepec Hotels](https://www.expedia.ca/San-Juan-Cacahuatepec-Hotels.d553248635640656455.Travel-Guide-Hotels) - [San Juan Teposcolula Hotels](https://www.expedia.ca/San-Juan-Teposcolula-Hotels.d553248635640662104.Travel-Guide-Hotels) - [San Lorenzo Victoria Hotels](https://www.expedia.ca/San-Lorenzo-Victoria-Hotels.d553248635640642582.Travel-Guide-Hotels) - [San Miguel Achiutla Hotels](https://www.expedia.ca/San-Miguel-Achiutla-Hotels.d553248635640633425.Travel-Guide-Hotels) - [San Miguel el Grande Hotels](https://www.expedia.ca/San-Miguel-El-Grande-Hotels.d553248635640667354.Travel-Guide-Hotels) - [Hotels near San Pedro y San Pablo Teposcolula Catholic Church](https://www.expedia.ca/San-Pedro-Y-San-Pablo-Teposcolula-Catholic-Church-Hotels.0-l553248635976234903-0.Travel-Guide-Filter-Hotels) - [San Pedro y San Pablo Teposcolula Hotels](https://www.expedia.ca/San-Pedro-Y-San-Pablo-Teposcolula-Hotels.d553248635640657811.Travel-Guide-Hotels) - [San Sebastián Tecomaxtlahuaca Hotels](https://www.expedia.ca/San-Sebastian-Tecomaxtlahuaca-Hotels.d553248635640660876.Travel-Guide-Hotels) - [San Simón Zahuatlán Hotels](https://www.expedia.ca/San-Simon-Zahuatlan-Hotels.d553248635640671156.Travel-Guide-Hotels) - [Santa María Yolotepec Hotels](https://www.expedia.ca/Santa-Maria-Yolotepec-Hotels.d553248635640679610.Travel-Guide-Hotels) - [Santa María Zacatepec Hotels](https://www.expedia.ca/Santa-Maria-Zacatepec-Hotels.d553248635640694662.Travel-Guide-Hotels) - [Santiago Juxtlahuaca Hotels](https://www.expedia.ca/Santiago-Juxtlahuaca-Hotels.d553248635640672179.Travel-Guide-Hotels) - [Santiago Miltepec Hotels](https://www.expedia.ca/Santiago-Miltepec-Hotels.d553248635640644121.Travel-Guide-Hotels) - [Santiago Tamazola Hotels](https://www.expedia.ca/Santiago-Tamazola-Hotels.d553248635640637097.Travel-Guide-Hotels) - [Santiago Yucuyachi Hotels](https://www.expedia.ca/Santiago-Yucuyachi-Hotels.d553248635640633085.Travel-Guide-Hotels) - [Tamazulapam Hotels](https://www.expedia.ca/Tamazulapam-Hotels.d6320679.Travel-Guide-Hotels) - [Tlacotepec Plumas Hotels](https://www.expedia.ca/Tlacotepec-Plumas-Hotels.d553248635640691895.Travel-Guide-Hotels) - [Tlaxiaco Hotels](https://www.expedia.ca/Tlaxiaco-Hotels.d3000367158.Travel-Guide-Hotels) - [Yanhuitlan Hotels](https://www.expedia.ca/Yanhuitlan-Hotels.d6354831.Travel-Guide-Hotels) - [Yutanduchi de Guerrero Hotels](https://www.expedia.ca/Yutanduchi-De-Guerrero-Hotels.d553248635640676414.Travel-Guide-Hotels) - [Zapotitlán Lagunas Hotels](https://www.expedia.ca/Zapotitlan-Lagunas-Hotels.d553248635640678078.Travel-Guide-Hotels) - [Flights to Huajuapan](https://www.expedia.ca/Cheap-Flights-To-Huajuapan.d6245105.Travel-Guide-Flights) - [Flights to Pinotepa Nacional](https://www.expedia.ca/Cheap-Flights-To-Pinotepa-Nacional.d3000449713.Travel-Guide-Flights) - [Flights to Santiago Juxtlahuaca](https://www.expedia.ca/Cheap-Flights-To-Santiago-Juxtlahuaca.d553248635640672179.Travel-Guide-Flights) - [Visit Asunción Nochixtlán](https://www.expedia.ca/Asuncion-Nochixtlan.dx6299360) - [Visit Chalcatongo de Hidalgo](https://www.expedia.ca/Chalcatongo-De-Hidalgo.dx553248635640677829) - [Visit Magdalena Apasco](https://www.expedia.ca/Magdalena-Apasco.dx553248635640675660) - [Visit Pinotepa Nacional](https://www.expedia.ca/Pinotepa-Nacional.dx3000449713) - [Visit Putla Villa de Guerrero](https://www.expedia.ca/Putla-Villa-De-Guerrero.dx553248635640677765) - [Visit San Andrés Huaxpaltepec](https://www.expedia.ca/San-Andres-Huaxpaltepec.dx553248635640665955) - [Visit San Andrés Lagunas](https://www.expedia.ca/San-Andres-Lagunas.dx553248635640637082) - [Visit San Andrés Zautla](https://www.expedia.ca/San-Andres-Zautla.dx553248635640667478) - [Visit San Jerónimo Sosola](https://www.expedia.ca/San-Jeronimo-Sosola.dx553248635640657921) - [Visit San Juan Bautista Tlachichilco](https://www.expedia.ca/San-Juan-Bautista-Tlachichilco.dx553248635640658855) - [Visit San Juan Mixtepec Distrito 08](https://www.expedia.ca/San-Juan-Mixtepec-Distrito-08.dx553248635640658582) - [Visit San Lorenzo Victoria](https://www.expedia.ca/San-Lorenzo-Victoria.dx553248635640642582) - [Visit San Martín Peras](https://www.expedia.ca/San-Martin-Peras.dx553248635640694317) - [Visit San Mateo Yucutindoo](https://www.expedia.ca/San-Mateo-Yucutindoo.dx553248635640676828) - [Visit San Pablo Huitzo](https://www.expedia.ca/San-Pablo-Huitzo.dx553248635640633619) - [Visit San Pablo Tijaltepec](https://www.expedia.ca/San-Pablo-Tijaltepec.dx553248635640698804) - [Visit San Sebastián Nicananduta](https://www.expedia.ca/San-Sebastian-Nicananduta.dx553248635640633633) - [Visit San Sebastián Tecomaxtlahuaca](https://www.expedia.ca/San-Sebastian-Tecomaxtlahuaca.dx553248635640660876) - [Visit Santa Cruz Tacache de Mina](https://www.expedia.ca/Santa-Cruz-Tacache-De-Mina.dx553248635640668519) - [Visit Santa María Ixcatlán](https://www.expedia.ca/Santa-Maria-Ixcatlan.dx553248635640639883) - [Visit Santiago Apoala](https://www.expedia.ca/Santiago-Apoala.dx553248635640634931) - [Visit Santiago Juxtlahuaca](https://www.expedia.ca/Santiago-Juxtlahuaca.dx553248635640672179) - [Visit Santiago Yolomécatl](https://www.expedia.ca/Santiago-Yolomecatl.dx553248635640671015) - [Visit Santiago Yosondúa](https://www.expedia.ca/Santiago-Yosondua.dx553248635640642062) - [Visit Santo Domingo Teojomulco](https://www.expedia.ca/Santo-Domingo-Teojomulco.dx553248635640678296) - [Visit Santo Tomás Ocotepec](https://www.expedia.ca/Santo-Tomas-Ocotepec.dx553248635640676897) - [Visit Santos Reyes Tepejillo](https://www.expedia.ca/Santos-Reyes-Tepejillo.dx553248635640671563) - [Visit Santos Reyes Yucuná](https://www.expedia.ca/Santos-Reyes-Yucuna.dx553248635640659560) - [Car rental Santiago Juxtlahuaca](https://www.expedia.ca/Car-Rentals-In-Santiago-Juxtlahuaca.d553248635640672179.Car-Rental-Guide) - [Fox Rental Cars Rental Cars in San Pedro y San Pablo Tequixtepec](https://www.expedia.ca/Fox-Rental-Cars-Car-Rentals-In-San-Pedro-Y-San-Pablo-Tequixtepec.d553248635640641988-c19.Car-Rental-Guide-Suppliers) - [Book Hotels in Santiago del Río on Expedia.mx](https://www.expedia.mx/Santiago-Del-Rio-Hoteles.d553248635640665145.Guia-Viajes-Hoteles) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)