Title: Book The Best Hotels in Santee, SC for 2025 from CA $79 - Competitive Prices - Expedia.ca [Santee Travel Guide](https://expedia.ca/Santee.dx9953)[Vacation Rentals in Santee](https://expedia.ca/Santee-Vacation-Rentals.d9953.Travel-Guide-VacationRentals)[Flights to Santee](https://expedia.ca/Cheap-Flights-To-Santee.d9953.Travel-Guide-Flights)[Santee Car Rentals](https://expedia.ca/Car-Rentals-In-Santee.d9953.Car-Rental-Guide)[Santee Vacation Packages](https://expedia.ca/Santee.d9953.Destination-Travel-Guides) ![Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina](https://images.trvl-media.com/place/9953/cd2a687d-b68e-41e2-9556-82dcf249bc2d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Santee, SC from CA $79 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santee Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2025-11-16&d1=2025-11-16&endDate=2025-11-18&d2=2025-11-18&amenities=PETS) Pool [](https://www.expedia.ca/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2025-11-16&d1=2025-11-16&endDate=2025-11-18&d2=2025-11-18&amenities=POOL) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2025-11-16&d1=2025-11-16&endDate=2025-11-18&d2=2025-11-18&travelerType=family_friendly) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2025-11-16&d1=2025-11-16&endDate=2025-11-18&d2=2025-11-18&lodging=APARTMENT) Cottage [](https://www.expedia.ca/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2025-11-16&d1=2025-11-16&endDate=2025-11-18&d2=2025-11-18&lodging=COTTAGE) Waterpark [](https://www.expedia.ca/Hotel-Search?destination=Santee%2C+South+Carolina%2C+United+States+of+America®ionId=9953&latLong=33.487602%2C-80.476242&adults=2&startDate=2025-11-16&d1=2025-11-16&endDate=2025-11-18&d2=2025-11-18&amenities=WATER_PARK) ## Check prices for these dates Tonight [Nov 2 - Nov 3](https://www.expedia.ca/Hotel-Search?regionId=9953&startDate=2025-11-02&endDate=2025-11-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 3 - Nov 4](https://www.expedia.ca/Hotel-Search?regionId=9953&startDate=2025-11-03&endDate=2025-11-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=9953&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=9953&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Compare 295 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable. ![Lobby](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/8f64bf7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/11da224f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/cce2b53c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Santee Santee 9.2/10 Wonderful (582) "Clean, safe and very comfortable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard CA $147 CA $163 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/8e89959e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/6e319d52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/91286f8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/520000/518500/518401/ddfa8a2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Santee Santee 8.0/10 Very good (1003) "Good place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) omar CA $147 CA $163 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/c7187353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/c5237c95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/25ebdfeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Santee Santee 8.0/10 Very good (1384) "A nice location, plenty of parking, nice that breakfast was included. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alyssa CA $105 CA $117 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5472b058.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/65520f0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5897ba97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Santee-I-95 Santee 9.6/10 Exceptional (1003) "Very nice hotel, very clean and super friendly staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley CA $171 CA $190 total includes taxes & fees Nov 11 - Nov 12 [](https://www.expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/170f28f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/67341601.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/e78e5670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Santee Santee 9.8/10 Exceptional (1003) "Great stay for a quick weekend getaway!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Danielle CA $170 CA $188 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/c82722a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/442e4efc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/278d9dc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/e27bc6de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Santee by IHG Santee 8.2/10 Very good (957) "Great hotel w" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elizabeth CA $165 CA $184 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/4ab49efd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/28717b40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/eeb5fa18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathtub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/ebe97e99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Santee Santee 7.0/10 Good (664) "Good location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica CA $87 CA $96 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) ![Business centre](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/3861a053.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds, Non Smoking](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/c97df40a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/10951979.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91280000/91274500/91274426/1295e8cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Santee 6.0/10 (445) "Clean n great owners " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stefan CA $82 CA $99 total includes taxes & fees Nov 8 - Nov 9 [](https://www.expedia.ca/Santee-Hotels-Royal-Inn.h91274426.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/6d1459c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/725815f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/4aad61ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21900/21863/ab86ecd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Santee Inn Santee 8.8/10 Excellent (1002) "The breakfast was good and people helpful and nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark CA $191 CA $212 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/41ed20e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/740d6803.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/d34bd120.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/11700/11623/61b41f5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Santee I-95 Santee 6.2/10 (537) "The grounds and property were clean and you could tell they take pride in what they're offering." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric CA $98 CA $108 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Orangeburg-Hotels-Clarion-Inn-Santee-I-95.h11623.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/4686cd8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/b105c391.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/8136c59d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/a90b57ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Santee Santee 6.6/10 (631) "It's a quiet tuck back hotel. Although the front desk lady was extremely rude and tried to over charge me several times. The property manager was very professional." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Monica CA $88 CA $98 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/Orangeburg-Hotels-Red-Roof-Inn-Santee.h856695.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/2fd60881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/aa634b56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/77599f7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1060000/1050100/1050011/2262fc91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Santee Santee 6.8/10 (436) "It's a very quiet hotel. My room was very spacious. And the bed was very comfortable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Monica CA $105 CA $117 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Orangeburg-Hotels-Super-8-By-Wyndham-Santee.h1050011.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/1f93ecf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/3b5b7fa1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/6c8567ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/910000/905400/905358/51caeaed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Santee 6.4/10 (309) "It was great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Linda CA $88 CA $98 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/Orangeburg-Hotels-Econo-Lodge.h905358.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/1bbd70f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/a4197341.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness studio](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/7b01c436.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/c836e9b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Orangeburg Orangeburg 9.2/10 Wonderful (1015) "It was nice and staff was very nice." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William CA $148 CA $165 total includes taxes & fees Nov 17 - Nov 18 [](https://www.expedia.ca/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/8acfa265.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3840h2556x0y4-5cb4ef80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/321b05a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/w3840h2557x0y3-a96a0495.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Orangeburg Orangeburg 7.8/10 Good (1003) "Rooms were clean and comfortable. Can’t speak to the breakfast as we had to leave before it opened, but overall we had a great peaceful sleep. Would definitely recommend staying there. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Martina CA $122 CA $136 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) ![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/377ba79f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Non Smoking (Efficiency)](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/1c1fc707.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/cc6b1fba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990272/208c4454.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Orangeburg Orangeburg 8.0/10 Very good (528) "I was satisfied with staff service and facilities." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gwendolyn CA $137 CA $152 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites.h1990272.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/2eadf4bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/a66aad1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/e088653f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/18900/18873/816f12dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham St George St. George 7.6/10 Good (1001) "Very pleasant stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Annie CA $89 CA $99 total includes taxes & fees Nov 4 - Nov 5 [](https://www.expedia.ca/St-George-Hotels-Days-Inn-By-Wyndham-St-George.h18873.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/54902f8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Two queen beds non smoking](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/e1b5940b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/ab9e6646.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1420000/1418700/1418684/8a3bfd5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Manning Manning 8.4/10 Very good (990) "Clean Easy room access, spacious couch and comfortable king bed combination room " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erika CA $167 CA $185 total includes taxes & fees Nov 14 - Nov 15 [](https://www.expedia.ca/Sumter-Hotels-Hampton-Inn-Manning.h1418684.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/300000/297200/297104/97d6098f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/300000/297200/297104/a152b78a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/300000/297200/297104/159dba3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/300000/297200/297104/02857169.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn Orangeburg Orangeburg 7.8/10 Good (371) "Friendly, helpful staff. Room is very nice, clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lori CA $113 CA $126 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Orangeburg-Hotels-Sleep-Inn-Orangeburg.h297104.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/e6b95688.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/b76457c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/fb97cba6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/570000/569400/569301/0ca73b4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SureStay Hotel by Best Western Manning Manning 8.6/10 Excellent (1006) "Parking ok, breakfast ok" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ada CA $133 CA $148 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Sumter-Hotels-SureStay-Hotel-By-Best-Western-Manning.h569301.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-16&endDate=2025-11-17®ionId=9953&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Hotels.d9953.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Hotels.d9953.Travel-Guide-Hotels) ## Learn more about Santee Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campgrounds. [See all hotels in Santee](https://www.expedia.ca/Hotel-Search?startDate=2025-11-16&endDate=2025-11-17&adults=2®ionId=9953) ![Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina](https://images.trvl-media.com/place/9953/cd2a687d-b68e-41e2-9556-82dcf249bc2d.jpg?impolicy=fcrop&w=899&h=634&p=1&q=high) ### Stay near popular Santee attractions Santee, South Carolina is an ideal destination for outdoor enthusiasts and those seeking a romantic getaway. Visitors can explore stunning natural attractions such as Santee State Park, along with beautiful lakes and islands. This charming locale offers a blend of beach activities and cultural experiences, catering to various interests for a memorable vacation. [](https://expedia.ca/Santee-State-Park-Hotels.0-l6140632-0.Travel-Guide-Filter-Hotels) #### Santee State Park 1/5(1 review) Santee State Park offers breathtaking scenery, thrilling outdoor adventures, and a vibrant atmosphere, making it a perfect destination for nature enthusiasts and those seeking relaxation. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6140632) [](https://expedia.ca/Santee-Cooper-Country-Club-Hotels.0-l553248621532654899-0.Travel-Guide-Filter-Hotels) #### Santee Cooper Country Club 5/5(1 review) Enjoy a round of golf at Santee Cooper Country Club, surrounded by lush landscapes, followed by relaxing outdoor activities like hiking and picnicking in nature's embrace. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532654899) [](https://expedia.ca/Santee-National-Golf-Club-Hotels.0-l553248621532654897-0.Travel-Guide-Filter-Hotels) #### Santee National Golf Club 1/5(1 review) Santee National Golf Club offers serene outdoor vibes with lush landscapes, perfect for rejuvenating walks, yoga sessions, and golf, providing a tranquil retreat for wellness enthusiasts. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532654897) ## More cheap stays in Santee ![Baymont by Wyndham Santee](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baymont by Wyndham Santee 249 Britain Street, Santee, SC CA $105 CA $117 total Nov 3 - Nov 4 includes taxes & fees 7.8/10 Good! (1,381 reviews) [](https://expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Tru By Hilton Santee](https://images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tru By Hilton Santee 263 Britain St. and 273 Britain St., Santee, SC CA $147 CA $163 total Nov 9 - Nov 10 includes taxes & fees 9/10 Wonderful! (581 reviews) [](https://expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Tru by Hilton Orangeburg](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323336/1bbd70f5_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tru by Hilton Orangeburg 739 Citadel Road, Orangeburg, SC CA $148 CA $165 total Nov 17 - Nov 18 includes taxes & fees 9/10 Wonderful! (1,010 reviews) [](https://expedia.ca/Orangeburg-Hotels-Tru-By-Hilton-Orangeburg.h34323336.Hotel-Information) ![Baymont by Wyndham Orangeburg North](https://images.trvl-media.com/lodging/1000000/30000/20500/20500/3438166f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baymont by Wyndham Orangeburg North 3583 Saint Matthews Rd, Orangeburg, SC CA $71 CA $79 total Nov 9 - Nov 10 includes taxes & fees 6/10 (1,000 reviews) [](https://expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Orangeburg-North.h20500.Hotel-Information) ![Fairfield Inn & Suites by Marriott Santee](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Fairfield Inn & Suites by Marriott Santee 9074 Old Number Six Hwy, Santee, SC CA $170 CA $188 total Dec 1 - Dec 2 includes taxes & fees 9.8/10 Exceptional! (1,003 reviews) [](https://expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Spark by Hilton Orangeburg](https://images.trvl-media.com/lodging/2000000/1880000/1878000/1877930/8acfa265_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Spark by Hilton Orangeburg 731 Citadel Road, Orangeburg, SC CA $122 CA $136 total Nov 9 - Nov 10 includes taxes & fees 7.6/10 Good! (1,005 reviews) [](https://expedia.ca/Orangeburg-Hotels-Spark-By-Hilton-Orangeburg.h1877930.Hotel-Information) ## Hotels in Santee with star-rating ![4 Star Hotels](https://images.trvl-media.com/lodging/44000000/44000000/43992600/43992569/bfd80ad8_w.jpg) 4 Star Hotels 1 properties [](https://expedia.ca/4Star-Santee-Hotels.s40-0-d9953.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/c82722a1_w.jpg) 3 Star Hotels 9 properties [](https://expedia.ca/3Star-Santee-Hotels.s30-0-d9953.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3_w.jpg) 2 Star Hotels 69 properties [](https://expedia.ca/2Star-Santee-Hotels.s20-0-d9953.Travel-Guide-Filter-Hotels) ## Find out more about Santee ### Top reasons to visit Santee - **Outdoor Adventures:** Santee offers stunning hiking trails and recreational areas perfect for outdoor enthusiasts. - **Santee State Park:** Explore beautiful lakes and nearby islands for a serene nature experience. - **Golfing:** Enjoy a round of golf at local courses amidst picturesque landscapes. - **Shopping:** Indulge in retail therapy at the nearby outlet mall for a well-rounded vacation. - **Accommodations for All:** A variety of hotels cater to diverse needs, ensuring a comfortable stay. ### Find great hotels in and around Santee Discover the charm of Santee, South Carolina, where a variety of hotels and motels cater to every traveller's needs. Whether you're seeking pet-friendly accommodations, a welcoming atmosphere for LGBTQIA guests, or business-focused amenities, Santee has you covered. With options ranging from the best hotels to top-rated choices, your ideal stay awaits in this picturesque destination. - **[Baymont by Wyndham Santee:](https://www.expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information)** Experience the charm of Santee at Baymont by Wyndham, a welcoming hotel that caters to both business and pet-friendly travellers. This property offers a comfortable stay with amenities designed for those on the go, including business facilities tailored for professional needs. With a flexible pet policy, guests can travel with their furry companions, ensuring that no family member is left behind. Enjoy the convenience of modern amenities while feeling right at home in this inviting atmosphere. - **[Fairfield Inn by Marriott Orangeburg:](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-By-Marriott-Orangeburg.h563976.Hotel-Information)** Just a short drive from Santee, the Fairfield Inn by Marriott Orangeburg stands out as an inclusive and business-friendly hotel. Known for its warm hospitality and LGBTQIA welcoming environment, this property is perfect for diverse travellers. Guests can take advantage of the 24-hour business centre, making it easy to stay productive during their visit. The hotel’s attention to creating an inclusive atmosphere is complemented by comfortable accommodations, ensuring a pleasant and stress-free stay. - **[Best Western Plus Santee Inn:](https://www.expedia.ca/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information)** Nestled in the heart of Santee, the Best Western Plus Santee Inn combines business amenities with a pet-friendly approach. This hotel features a comprehensive business centre, conference space, and meeting rooms, making it ideal for both corporate gatherings and leisure travellers alike. With a welcoming environment for pets, guests can enjoy the added benefit of a dog exercise area, allowing their pets to stretch their legs. The blend of professional facilities and home-like comfort ensures a memorable stay for all. ### Where to stay near Santee Santee, South Carolina, offers a perfect blend of outdoor adventures and serene getaways for Canadian travellers. Nestled among scenic views and tranquil waters, this charming city is ideal for romantic escapes or family-friendly excursions. Nearby regions boast a friendly atmosphere and budget-friendly options, ensuring a memorable experience for all. Whether you seek a quieter retreat or vibrant outdoor activities, Santee has something for everyone to enjoy. - **[Summerton:](https://www.expedia.ca/Summerton-Hotels.d163488.Travel-Guide-Hotels)** Located 17.7km from Santee, Summerton offers a charming small-town atmosphere with a focus on outdoor activities and natural beauty. Visitors are drawn to its scenic landscapes, making it an ideal destination for a romantic getaway. The peak travel seasons in March to April and July enhance its appeal, as travellers can enjoy recreational areas and golf courses. Nearby attractions include picturesque lakes and the stunning national state park, providing ample opportunities for exploration and relaxation in nature. - **[Vance:](https://www.expedia.ca/Vance-Hotels.d3000456153.Travel-Guide-Hotels)** Situated just 8.0km from Santee, Vance is a quaint city that experiences highly seasonal visitor patterns, particularly in March to April and July. Known for its outdoor offerings and scenic vistas, Vance is perfect for couples seeking a romantic escape. With access to recreational areas and golf courses, guests can enjoy leisurely outdoor activities. Local landmarks such as beautiful lakes, the national state park, and nearby islands make Vance a delightful stop for those looking to immerse themselves in South Carolina's natural beauty. - **[Elloree:](https://www.expedia.ca/Elloree-Hotels.d3000455923.Travel-Guide-Hotels)** Only 9.7km away from Santee, Elloree is a vibrant city that attracts visitors year-round, with peak periods in March, July, and September. This charming location is ideal for outdoor enthusiasts and couples seeking scenic experiences. Guests can enjoy a variety of activities, including access to golf courses and recreational spaces. Notable nearby attractions include tranquil lakes and the captivating national park, making Elloree a fantastic spot for nature lovers to unwind and explore the great outdoors. ### Things to do in and around Santee Santee, South Carolina, is perfect for outdoor enthusiasts and couples seeking a romantic getaway. Enjoy activities like hiking scenic trails, playing a round of golf at one of the local golf courses, or exploring the recreational areas. After a day of adventure, unwind with the nightlife options available or indulge in some shopping at the nearby outlet mall, ensuring a well-rounded vacation experience. **Shopping** In Santee, check out local gem [Bee City](https://www.expedia.ca/Bee-City-Hotels.0-l553248621532654894-0.Travel-Guide-Filter-Hotels) for unique gifts. If you're up for a drive, visit Pocalla Crossing Shopping Center, located 43.5km away, featuring a variety of shops and a family-friendly atmosphere, perfect for souvenirs and local finds. **Recreation** [Santee Cooper Country Club](https://www.expedia.ca/Santee-Cooper-Country-Club-Hotels.0-l553248621532654899-0.Travel-Guide-Filter-Hotels) offers a scenic golfing experience amid lush landscapes, perfect for sports enthusiasts. [Santee National Wildlife Refuge](https://www.expedia.ca/Santee-National-Wildlife-Refuge-Hotels.0-l553248621532654901-0.Travel-Guide-Filter-Hotels) provides a serene retreat for relaxation and nature appreciation, while [Patriots Sports Plex](https://www.expedia.ca/Patriots-Sports-Plex-Hotels.0-l553248623546509706-0.Travel-Guide-Filter-Hotels) features various recreational activities to rejuvenate your spirit and promote wellness. **Adventure** Santee State Park offers thrilling opportunities for hiking, fishing, and canoeing amidst beautiful landscapes. Explore the scenic trails or cast a line into the tranquil waters of Lake Marion, where you can enjoy peaceful surroundings and spot local wildlife in their natural habitat. **Nightlife** Santee offers a laid-back nightlife scene, perfect for unwinding after a day of exploration. Enjoy live music at the local pubs or relax by the lake with friends. The nearby restaurants offer cozy atmospheres for evening dining, making it an ideal spot for a casual night out. *\*Distances are measured in a straight line; actual driving distances may vary depending on the route.* ### Booking tips and Expedia advantages for Santee Santee, South Carolina, is a budget-friendly destination with free entry to attractions like Taw Caw Creek. To save on accommodations, consider visiting between December and February, with Mondays typically offering the lowest rates. For getting around, options include cars, buses, and bikes. Utilize Expedia to find eco-certified hotels and combine your hotel, flights, and activities for additional savings. Remember, Saturdays are the priciest days to stay, so planning around this can help you save more during your visit. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in Santee are December to February, where the prices are slightly lower. This is in comparison to April to May and October, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Santee is Monday. The most expensive day to stay in Santee is Saturday. - **Find cheap hotels on Expedia:** Utilize Expedia's search tool to refine your preferences, such as your budget, desired location, and preferred type of accommodation. For instance, selecting the Eco-certified option will showcase sustainable and environmentally friendly hotels currently available. To find the best prices and offers, sort the price filter from lowest to highest. - **Consider bundling your trip:** You can save money by combining your hotel stay in Santee with your flights and activities through an Expedia package. ### Best time to go to Santee The best time to visit Santee is dependant on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | --- | --- | --- | --- | --- | --- | | January | 47.3°F (8.5°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | February | 51.4°F (10.8°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | March | 56.8°F (13.8°C) | Light Rain | Mostly Sunny | Slightly High | Average | | April | 64.4°F (18.0°C) | Light Rain | Mostly Sunny | Slightly High | Slightly High | | May | 72.0°F (22.2°C) | Light Rain | Mostly Sunny | Average | Slightly High | | June | 78.6°F (25.9°C) | Light Rain | Mostly Sunny | Average | Average | | July | 81.5°F (27.5°C) | Light Rain | Mostly Sunny | Slightly High | Average | | August | 79.9°F (26.6°C) | Light Rain | Mostly Sunny | Average | Average | | September | 75.4°F (24.1°C) | Light Rain | Mostly Sunny | Average | Average | | October | 66.4°F (19.1°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly High | | November | 56.1°F (13.4°C) | Light Rain | Mostly Sunny | Slightly Low | Average | | December | 51.3°F (10.7°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly Low | ### The nearest major airports for your trip to Santee For your visit to Santee, South Carolina, you can conveniently fly into two major airports. Charleston International Airport ([CHS](https://www.expedia.ca/Charleston-Intl-Airport-Hotels.0-aCHS-0.Travel-Guide-Filter-Hotels)) is situated 78.9km away, with excellent hotel options like [The Charleston Place](https://www.expedia.ca/Charleston-Hotels-Charleston-Place.h28504.Hotel-Information), [The Dewberry Charleston](https://www.expedia.ca/Charleston-Hotels-The-Dewberry-Charleston.h12880056.Hotel-Information), and [Hotel Bennett](https://www.expedia.ca/Charleston-Hotels-Hotel-Bennett.h22649862.Hotel-Information), all 14.5km from the airport and offering transfers and shuttles. Alternatively, Columbia Metropolitan Airport ([CAE](https://www.expedia.ca/Columbia-Metropolitan-Airport-Hotels.0-aCAE-0.Travel-Guide-Filter-Hotels)) is also 78.9km from Santee, with hotels such as [Graduate by Hilton Columbia SC](https://www.expedia.ca/Columbia-Hotels-Graduate-Columbia.h2515057.Hotel-Information), [Doubletree by Hilton Columbia](https://www.expedia.ca/Columbia-Hotels-Doubletree-By-Hilton-Columbia.h1090.Hotel-Information), and [Marriott Columbia](https://www.expedia.ca/Columbia-Hotels-Marriott-Columbia.h17353.Hotel-Information) located 6 to 11.3km away, providing easy access to the airport. Both airports ensure a smooth travel experience to your destination. ## Recent reviews of Santee hotels ![Baymont by Wyndham Santee](//images.trvl-media.com/lodging/1000000/20000/15400/15379/1987eeb3_y.jpg) ### Baymont by Wyndham Santee 5/5 Excellent "Best night's sleep I've had on the road. Friendly, helpful staff accommodated my needs of ground floor room. " A verified traveller stayed at Baymont by Wyndham Santee Posted 3 days ago [](https://expedia.ca/Orangeburg-Hotels-Baymont-By-Wyndham-Santee.h15379.Hotel-Information) ![Tru By Hilton Santee](//images.trvl-media.com/lodging/93000000/92610000/92601000/92600969/5c693db6_y.jpg) ### Tru By Hilton Santee 5/5 Excellent "Easy off/on I-95, staff very nicely accommodated my request to refreeze some ice packs I had to keep medicine cold while traveling and quickly retrieved ice packs for me in morning, staff very friendly and efficient. Room was nice and well stocked with towels soaps etc and bed very clean" A verified traveller stayed at Tru By Hilton Santee Posted 4 days ago [](https://expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information) ![Comfort Inn & Suites Santee](//images.trvl-media.com/lodging/1000000/520000/518500/518401/8e89959e_y.jpg) ### Comfort Inn & Suites Santee 5/5 Excellent "I like the smell" A verified traveller stayed at Comfort Inn & Suites Santee Posted 6 days ago [](https://expedia.ca/Orangeburg-Hotels-Comfort-Inn-Suites-Santee.h518401.Hotel-Information) ![Hampton Inn Santee-I-95](//images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276_y.jpg) ### Hampton Inn Santee-I-95 5/5 Excellent "every thing was great" A verified traveller stayed at Hampton Inn Santee-I-95 Posted 7 days ago [](https://expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) ![Fairfield Inn & Suites by Marriott Santee](//images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb_y.jpg) ### Fairfield Inn & Suites by Marriott Santee 5/5 Excellent "Staff was friendly and room was clean and comfortable " A verified traveller stayed at Fairfield Inn & Suites by Marriott Santee Posted 10 days ago [](https://expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) ![Best Western Plus Santee Inn](//images.trvl-media.com/lodging/1000000/30000/21900/21863/6d1459c3_y.jpg) ### Best Western Plus Santee Inn 5/5 Excellent "This is a great place to stop on our drive South. It has gotten more expensive. " A verified traveller stayed at Best Western Plus Santee Inn Posted 2 weeks ago [](https://expedia.ca/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information) ![Holiday Inn Santee by IHG](//images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/c82722a1_y.jpg) ### Holiday Inn Santee by IHG 5/5 Excellent "Great hotel w" A verified traveller stayed at Holiday Inn Santee by IHG Posted 3 weeks ago [](https://expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) ![Travelodge by Wyndham Santee](//images.trvl-media.com/lodging/6000000/5640000/5630800/5630775/4ab49efd_y.jpg) ### Travelodge by Wyndham Santee 5/5 Excellent "The counter tops and appliances needed cleaning, they were greasy. Otherwise the room was okay." A verified traveller stayed at Travelodge by Wyndham Santee Posted 1 month ago [](https://expedia.ca/Orangeburg-Hotels-Travelodge-By-Wyndham-Santee.h5630775.Hotel-Information) ![Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!](//images.trvl-media.com/lodging/92000000/91790000/91788500/91788460/dc99579a_y.jpg) ### Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95! 5/5 Excellent "Great house, very modern interior. Very clean. Close to town. We’ll definitely book the house on our fishing trip. " A verified traveller stayed at Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95! Posted 1 month ago [](https://expedia.ca/Santee-Hotels-This-House-Is-A-3-Bedroom.h91788460.Hotel-Information) ## Frequently asked questions ### What are the most popular pet-friendly hotels in Santee? > Some of the most popular pet-friendly hotels in Santee are [Fairfield Inn & Suites by Marriott Santee](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information), [Hampton Inn Santee-I-95](https://www.expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information), and [Tru By Hilton Santee](https://www.expedia.ca/Santee-Hotels-Tru-By-Hilton-Santee.h92600969.Hotel-Information). > > > > The Fairfield Inn & Suites by Marriott Santee, with a 9.8 rating, is highly praised by guests for its comfortable and clean rooms, as well as an excellent complimentary breakfast. It also offers free parking for RVs and buses, which can be convenient for travellers with larger vehicles. > > > > Hampton Inn Santee-I-95, rated 9.6, stands out for its friendly and helpful staff and delicious complimentary breakfast. Guests frequently comment on the comfortable and modern amenities available, ensuring a pleasant stay for both pets and their owners. > > > > Tru By Hilton Santee, with a 9.2 rating, is known for its clean rooms and exceptionally helpful staff at the front desk. The hotel provides a complimentary buffet breakfast and free toiletries, adding value to the stay. > > > > [Best Western Plus Santee Inn](https://www.expedia.ca/Orangeburg-Hotels-Best-Western-Plus-Santee-Inn.h21863.Hotel-Information), with an 8.8 rating, offers nice, clean rooms with super comfortable beds, according to guest feedback. A free continental breakfast is also provided, which is often described as delicious. > > > > The 3-star [Holiday Inn Santee by IHG](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information), rated 8.2, is appreciated for its clean and quiet rooms and helpful staff. Guests frequently mention the comfortable beds, ensuring a good night's sleep for everyone. ### How much does a pet-friendly hotel in Santee cost? > You can find pet-friendly hotels in Santee from CA $79 with Expedia. Staying at a pet-friendly hotel offers a convenient and welcoming experience for travellers who don't want to leave their furry companions behind. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates. ### Which area of Santee is best to stay in for pet-friendly hotels? > The best area to stay in Santee for pet-friendly hotels is along the US-15 and US-301 corridors, particularly around the I-95 interchange. > > > > This area is the primary commercial centre of Santee, offering a good selection of hotels, restaurants, and essential services geared towards travellers. You'll find most of the lodging options concentrated here, making it convenient for those travelling with pets to find suitable accommodation. The general layout is practical, with easy access to major roads. > > > > Families travelling with pets will find this area particularly convenient. Most hotels here are accustomed to guests with animals, often providing designated pet relief areas and sometimes even welcome amenities for furry friends. The ease of access to the interstate also means less stress when arriving or departing with pets, as you won't have to navigate through residential areas. > > > > For couples looking for a comfortable stopover with their pets, this area offers practical advantages. Many hotels provide comfortable rooms, and the proximity to dining options means you won't have to travel far for a meal after settling your pet. ### What are some great pet-friendly hotels in Santee with outdoor spaces? > For pet-friendly hotels in Santee offering outdoor spaces, consider the [Fairfield Inn & Suites by Marriott Santee](https://www.expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information), [Hampton Inn Santee-I-95](https://www.expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information), and [Holiday Inn Santee by IHG](https://www.expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information). > > > > The Fairfield Inn & Suites by Marriott Santee, with a 9.8 rating, features a patio for guests and their pets to enjoy. Reviewers frequently praise the excellent and friendly staff, as well as the comfortable and clean rooms. > > > > The Hampton Inn Santee-I-95, rated 9.6, provides a terrace, offering a pleasant outdoor area. Guests often highlight the friendly and helpful staff, along with comfortable and clean rooms. > > > > The Holiday Inn Santee by IHG, a 3-star hotel with an 8.2 rating, also offers a terrace. Its clean and quiet rooms, along with friendly staff, are often mentioned positively by guests. ### How do I ensure I have booked a pet-friendly room in Santee? > To ensure you've booked a pet-friendly room on Expedia, use the filters in your search and select "Pet friendly" under the "Amenities" section. This will narrow your options to properties that allow pets. Once you find a hotel you're interested in, click on it and review the "Policies" section for specific details about their pet policy. This often includes information about pet types, size restrictions, fees, and whether pets are allowed in all rooms or only certain ones.When selecting your room type, read the room description to check that its pet-friendly, as not all rooms in a pet-friendly hotel may accommodate pets. For added peace of mind, contact the hotel directly to confirm the room you've selected allows pets. ### What pet-friendly activities should we do in Santee? > There are a few pet-friendly activities to enjoy with your furry friends in Santee. > > > > For those who enjoy the outdoors, a walk along the Santee State Park trails is a wonderful option. Many of the trails welcome well-behaved, leashed dogs, offering scenic views of Lake Marion and the surrounding woodlands. It's a great way to get some exercise and fresh air together. > > > > Another excellent choice for pet owners is visiting the Santee National Wildlife Refuge. This vast area provides pathways and observation points where you can explore with your leashed pet, observing local wildlife in their natural habitat. ### What amenities should I look for in a pet-friendly hotel in Santee? > When selecting a hotel in Santee for you and your pet, look for amenities like food and water bowls, pet-friendly outdoor spaces and pet beds. You may find hotels that go the extra mile with pet-friendly dining options, treats and toys. It's also worth looking to see if there are any pet-friendly parks or walking trails nearby. ### How can I save on a pet-friendly hotel in Santee with Expedia? > There are plenty of ways to save on a pet-friendly hotel in Santee. Join [One Key™](https://www.expedia.ca/welcome-one-key)—Expedia's free travel rewards program—to unlock discounted Member Prices. Typically, booking in advance will help you save on your pet-friendly hotel booking. ### Do any Santee hotels have restrictions on pet sizes or breeds? > First ensure you have picked a pet-friendly hotel by using the "Pet friendly" filter under the "Amenities" section in your search. If a hotel in Santee has restrictions on pet sizes or breeds, you will find this information clearly in their property listing on Expedia. When you're on the property listing page, simply click on "Policies" to see what pet-specific policies the hotel implements. ### Is it cheaper to book flights and a pet-friendly hotel in Santee as a package? > Booking a hotel and flight package on Expedia can be cheaper than booking flights and hotels separately. Bundling can lead to significant savings, especially for international travel or when booking well in advance. However, savings vary depending on factors like destination, travel dates, and availability, so it's wise to compare options. With access to over 300,000 hotels worldwide, Expedia makes it easy to build the perfect travel package. ### Can I cancel my pet-friendly hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline. This is often within 24-48 hours of your scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use Expedia's "Fully refundable property" filter during your search to find the right pet-friendly hotel in Santee for you. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - More ways to book - [5 Star Hotels in Manning](https://www.expedia.ca/5Star-Manning-Hotels.s50-0-d8454.Travel-Guide-Filter-Hotels) - [Alcolu Hotels](https://www.expedia.ca/Alcolu-Hotels.d3000422483.Travel-Guide-Hotels) - [B&B in Bowman](https://www.expedia.ca/Bowman-Bed-And-Breakfast.d553248634998681915-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Red Roof Inn Hotels in Bowman](https://www.expedia.ca/Bowman-Hotels-Red-Roof-Inn.0-0-d553248634998681915--bRedRoofInn.Travel-Guide-Filter-Hotels) - [Bowman Hotels](https://www.expedia.ca/Bowman-Hotels.d553248634998681915.Travel-Guide-Hotels) - [Branchville Hotels](https://www.expedia.ca/Branchville-Hotels.d3000455875.Travel-Guide-Hotels) - [Apartments in Brookdale](https://www.expedia.ca/Brookdale-Apartments.d553248634999003908-aaApartments.Travel-Guide-Accommodation) - 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