Title: Book the Best BUSINESS Hotels in Santa Maria in 2026 | Expedia.ca [Santa Maria Travel Guide](https://expedia.ca/Santa-Maria.dx3224)[Hotels in Santa Maria](https://expedia.ca/Santa-Maria-Hotels.d3224.Travel-Guide-Hotels)[Vacation Rentals in Santa Maria](https://expedia.ca/Santa-Maria-Vacation-Rentals.d3224.Travel-Guide-VacationRentals)[Flights to Santa Maria](https://expedia.ca/Cheap-Flights-To-Santa-Maria.d3224.Travel-Guide-Flights)[Things to do in Santa Maria](https://expedia.ca/Things-To-Do-In-Santa-Maria.d3224.Travel-Guide-Activities)[Santa Maria Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Maria.d3224.Car-Rental-Guide)[Santa Maria Vacation Packages](https://expedia.ca/Santa-Maria.d3224.Destination-Travel-Guides) ![Vineyard in Santa Maria California; Shutterstock ID 206444242](https://images.trvl-media.com/place/3224/ba8b33be-89d4-4e66-b78a-b7d7bf6cc964.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Santa Maria, CA from CA $110 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Maria Business Hotels Tonight [Dec 12 - Dec 13](https://www.expedia.ca/Hotel-Search?regionId=3224&startDate=2025-12-12&endDate=2025-12-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 13 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=3224&startDate=2025-12-13&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=3224&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=3224&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Santa Maria business-friendly hotels ![Restaurant](https://images.trvl-media.com/lodging/1000000/20000/12500/12424/w3840h2557x0y3-fef746b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/12500/12424/w3837h2557x3y3-e09a7f68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/12500/12424/w3836h2557x4y3-8640246b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/12500/12424/w3837h2557x3y3-19ccb77e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites by Hilton Santa Maria [](https://www.expedia.ca/Santa-Maria-Hotels-Homewood-Suites-By-Hilton-Santa-Maria.h12424.Hotel-Information) Santa Maria 8.4/10 Very good (35) "Friendly staff and nice hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elisa CA $136 CA $153 total includes taxes & fees Jan 9 - Jan 10, 2026 [](https://www.expedia.ca/Santa-Maria-Hotels-Homewood-Suites-By-Hilton-Santa-Maria.h12424.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/39000000/38230000/38230000/38229980/1cf0eed4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/39000000/38230000/38230000/38229980/0f7b2fce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, cribs/infant beds](https://images.trvl-media.com/lodging/39000000/38230000/38230000/38229980/d9c1ee80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar](https://images.trvl-media.com/lodging/39000000/38230000/38230000/38229980/d2f85309.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Santa Maria [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hampton-Inn-Suites-Santa-Maria.h38229980.Hotel-Information) Santa Maria 9.4/10 Exceptional (1002) "Lovely hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Adrian CA $148 CA $166 total includes taxes & fees Dec 30 - Dec 31 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hampton-Inn-Suites-Santa-Maria.h38229980.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/20400/20393/53eb999c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Master Suite | Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/20400/20393/7f2c7157.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Master Suite](https://images.trvl-media.com/lodging/1000000/30000/20400/20393/b334fb79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20400/20393/0396337b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Historic Santa Maria Inn [](https://www.expedia.ca/Santa-Maria-Hotels-Historic-Santa-Maria-Inn.h20393.Hotel-Information) Santa Maria 8.4/10 Very good (1849) "Great place to stay the staff very friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Raffy CA $108 CA $121 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Santa-Maria-Hotels-Historic-Santa-Maria-Inn.h20393.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/20000/15400/15345/fda3cb7d_edited_c5f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/20000/15400/15345/dc279f99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking (Oversized Room;with Sofabed)](https://images.trvl-media.com/lodging/1000000/20000/15400/15345/50e2f2cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15345/w5755h3835x5y5-f126bb4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Big America [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Best-Western-Plus-Big-America.h15345.Hotel-Information) Santa Maria 8.8/10 Excellent (1002) "great place - clean n comfy beds " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nancy CA $143 CA $161 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Best-Western-Plus-Big-America.h15345.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/440000/433700/433636/71e9333e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/440000/433700/433636/578eeb28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/440000/433700/433636/33b4a0e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/440000/433700/433636/f81f9296.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Hotel Santa Maria [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Radisson-Hotel-Santa-Maria.h433636.Hotel-Information) Santa Maria 7.6/10 Good (1325) "Very nice hotel. It is currently being renovated." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elsa CA $136 CA $153 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Radisson-Hotel-Santa-Maria.h433636.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/40000000/39520000/39514500/39514495/ecb45d63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, individually decorated](https://images.trvl-media.com/lodging/40000000/39520000/39514500/39514495/2f1d1804.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/40000000/39520000/39514500/39514495/c2079151.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/40000000/39520000/39514500/39514495/1bbd8589.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wine Stone Inn [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Wine-Stone-Inn.h39514495.Hotel-Information) Santa Maria 9.8/10 Exceptional (600) "Room was super clean and roomy ...bed was very comfortable! Love the decor in the entire hotel. Staff was friendly and accommodating. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) shannon CA $216 CA $258 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Wine-Stone-Inn.h39514495.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2740000/2733300/2733222/6f4a6585.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2740000/2733300/2733222/be90ec77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2740000/2733300/2733222/d7a2a144.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/3000000/2740000/2733300/2733222/0b303e7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Santa Maria [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Fairfield-Inn-Suites-By-Marriott-Santa-Maria.h2733222.Hotel-Information) Santa Maria 8.6/10 Excellent (721) "Staff for breakfast" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kiari CA $154 CA $174 total includes taxes & fees Dec 30 - Dec 31 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Fairfield-Inn-Suites-By-Marriott-Santa-Maria.h2733222.Hotel-Information) ![Studio Suite, 2 Double Beds](https://images.trvl-media.com/lodging/3000000/2620000/2618300/2618252/0df55700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/3000000/2620000/2618300/2618252/40c6d2ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/3000000/2620000/2618300/2618252/11245da2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2620000/2618300/2618252/5fae8499.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Candlewood Suites Santa Maria by IHG [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Candlewood-Suites-Santa-Maria.h2618252.Hotel-Information) Santa Maria 8.6/10 Excellent (1000) "Clean room . Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Derek CA $139 CA $157 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Candlewood-Suites-Santa-Maria.h2618252.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1090000/1088200/1088174/cc3976ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1090000/1088200/1088174/0e007283.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds](https://images.trvl-media.com/lodging/2000000/1090000/1088200/1088174/483bd489.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/2000000/1090000/1088200/1088174/b5ae9feb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Santa Maria [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Days-Inn-By-Wyndham-Santa-Maria.h1088174.Hotel-Information) Santa Maria 6.8/10 (1000) "Room was clean staff was nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly Dawn CA $98 CA $111 total includes taxes & fees Dec 17 - Dec 18 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Days-Inn-By-Wyndham-Santa-Maria.h1088174.Hotel-Information) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/24800/24701/499bf389.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24800/24701/bec53989.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/30000/24800/24701/41e1ae07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/1000000/30000/24800/24701/9f6137db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Buellton - Solvang [](https://www.expedia.ca/Santa-Barbara-Hotels-Quality-Inn-Buellton-Solvang.h24701.Hotel-Information) Buellton 8.8/10 Excellent (1120) "good breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) alejandra CA $92 CA $110 total includes taxes & fees Jan 7 - Jan 8, 2026 [](https://www.expedia.ca/Santa-Barbara-Hotels-Quality-Inn-Buellton-Solvang.h24701.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-27&endDate=2025-12-28®ionId=3224&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Santa Maria Hotel Reviews ![Pea Soup Andersen's Inn](https://images.trvl-media.com/lodging/1000000/20000/19400/19331/1b7acd45_y.jpg) ### Pea Soup Andersen's Inn 10/10 Excellent "The front office staff was friendly and was helpful " [](https://expedia.ca/Santa-Barbara-Hotels-Pea-Soup-Andersens-Inn.h19331.Hotel-Information) ![Homewood Suites by Hilton Santa Maria](https://images.trvl-media.com/lodging/1000000/20000/12500/12424/w3837h2556x3y4-e2ba7794_y.jpg) ### Homewood Suites by Hilton Santa Maria 10/10 Excellent "rooms are absolutely beautiful. Breakfast was delicious. Only thing I didn’t like. Is you pay $10 a night per parking per vehicle highly recommend " [](https://expedia.ca/Santa-Maria-Hotels-Homewood-Suites-By-Hilton-Santa-Maria.h12424.Hotel-Information) ![Vinland Hotel and Lounge](https://images.trvl-media.com/lodging/1000000/20000/19500/19473/cd77ad55_y.jpg) ### Vinland Hotel and Lounge 10/10 Excellent "Great service, lovely lady ant the counter, and even allowed for an early check in. Much appreciated! " [](https://expedia.ca/Santa-Barbara-Hotels-Vinland-Hotel-And-Lounge.h19473.Hotel-Information) ![Historic Santa Maria Inn](https://images.trvl-media.com/lodging/1000000/30000/20400/20393/53eb999c_y.jpg) ### Historic Santa Maria Inn 10/10 Excellent "My stay was great!" [](https://expedia.ca/Santa-Maria-Hotels-Historic-Santa-Maria-Inn.h20393.Hotel-Information) ![Spyglass Inn](https://images.trvl-media.com/lodging/1000000/50000/41300/41235/44c3350f_y.jpg) ### Spyglass Inn 10/10 Excellent "View was amazing, large clean room" [](https://expedia.ca/San-Luis-Obispo-Hotels-Spyglass-Inn.h41235.Hotel-Information) ![SeaCrest OceanFront Hotel](https://images.trvl-media.com/lodging/2000000/1370000/1365400/1365352/w3000h1999x0y0-15b2e131_y.jpg) ### SeaCrest OceanFront Hotel 10/10 Excellent "Everything was amazing ! I love staying at Seacrest " [](https://expedia.ca/San-Luis-Obispo-Hotels-SeaCrest-OceanFront-Hotel.h1365352.Hotel-Information) ![Edgewater Inn And Suites](https://images.trvl-media.com/lodging/1000000/900000/894000/893902/3d1c5694_y.jpg) ### Edgewater Inn And Suites 10/10 Excellent "Clean rooms" [](https://expedia.ca/San-Luis-Obispo-Hotels-Edgewater-Inn-And-Suites.h893902.Hotel-Information) ![Embassy Suites by Hilton San Luis Obispo](https://images.trvl-media.com/lodging/1000000/20000/15500/15406/48c2929b_y.jpg) ### Embassy Suites by Hilton San Luis Obispo 10/10 Excellent "Customer service, clean rooms and cocktail hour" [](https://expedia.ca/San-Luis-Obispo-Hotels-Embassy-Suites-By-Hilton-San-Luis-Obispo.h15406.Hotel-Information) ![Wine Valley Inn](https://images.trvl-media.com/lodging/1000000/50000/41300/41236/92aad964_y.jpg) ### Wine Valley Inn 10/10 Excellent "The cottage was beautiful! We had a spa and the room was huge! Cottage 3 is where it’s at!" [](https://expedia.ca/Santa-Barbara-Hotels-Wine-Valley-Inn.h41236.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Santa Maria cost? ### What are the best business-friendly hotels in Santa Maria? ### How many business-friendly hotels are there in Santa Maria? ### What are the best cheap business-friendly hotels in Santa Maria? ### What are the top business-friendly motels in Santa Maria? ### Are there any family-friendly hotels in Santa Maria that are also business friendly? ### Why book your business-friendly hotel in Santa Maria with Expedia? ### How can I find cheap business-friendly hotels in Santa Maria? ### What is there to do in Santa Maria near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Adults Only Resorts & in Central Coast California ](https://www.expedia.ca/Central-Coast-California-Hotels-Adults-Only-Resorts.0-0-d6055477-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - 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