Find hotels in Santa Fe, FL from CA $84

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
May 12 - May 13
Tomorrow
May 13 - May 14
This weekend
May 15 - May 17
Next weekend
May 22 - May 24

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Fe hotels

Free daily full breakfast

Holiday Inn Express Starke by IHG

Holiday Inn Express Starke by IHG
2.5 star property
Starke
9.6 out of 10, Exceptional, (549 reviews)
"Facility was very clean and breakfast was very good. Would definitely stay again. "
United States
Sheila
The price is CA $167
CA $185 total
includes taxes & fees
May 31 - Jun 1
Holiday Inn Express Starke by IHG
Outdoor pool

Best Western Waldo Inn and Suites

Best Western Waldo Inn and Suites
2.5 star property
Waldo
8.8 out of 10, Excellent, (999 reviews)
"The breakfast area was clean. Enjoyed the wide selection of food."
United States
Jeanne
The price is CA $139
CA $157 total
includes taxes & fees
May 24 - May 25
Best Western Waldo Inn and Suites
Lobby

Comfort Suites Gainesville near University

Comfort Suites Gainesville near University
2.5 star property
Gainesville
9.2 out of 10, Wonderful, (1,347 reviews)
"Very nice and clean, good breakfast"
United States
Natalya
The price is CA $129
CA $145 total
includes taxes & fees
May 24 - May 25
Comfort Suites Gainesville near University
Exterior

La Quinta by Wyndham Gainesville

La Quinta by Wyndham Gainesville
3.0 star property
Gainesville
9.0 out of 10, Wonderful, (1,223 reviews)
"The hotel was clean, complementary breakfast was better than most, bed was comfortable, and the room was spacious. We would definitely stay here again."
United States
MICHELLE
The price is CA $128
CA $144 total
includes taxes & fees
May 13 - May 14
La Quinta by Wyndham Gainesville
Exterior

Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL
3.0 star property
Gainesville
9.2 out of 10, Wonderful, (1,817 reviews)
"We had the best stay here. Will stay here the next time we are in town! "
United States
Elisabeth
The price is CA $126
CA $142 total
includes taxes & fees
May 26 - May 27
Country Inn & Suites by Radisson, Gainesville, FL
Standard Double Room

Soho Inn Waldo

Soho Inn Waldo
2.0 star property
Waldo
5.2 out of 10, (20 reviews)
"Clean linens and towels, lots of parking, room is newly painted. There’s TV, A/C, microwave. Receptionist is very nice. "
Canada
Cynthia
The price is CA $96
CA $108 total
includes taxes & fees
May 14 - May 15
Soho Inn Waldo
Exterior

Super 8 by Wyndham Gainesville I-75 Hospital University Area

Super 8 by Wyndham Gainesville I-75 Hospital University Area
2.0 star property
Gainesville
7.6 out of 10, Good, (1,018 reviews)
"Clean room, welcoming staff, location great"
United States
Jon
The price is CA $74
CA $84 total
includes taxes & fees
May 17 - May 18
Super 8 by Wyndham Gainesville I-75 Hospital University Area
Lobby

Drury Inn & Suites Gainesville

Drury Inn & Suites Gainesville
3.0 star property
Gainesville
9.6 out of 10, Exceptional, (1,474 reviews)
"Everything about our stay was perfect. The staff is friendly and I loved the breakfast. "
United States
Gregory
The price is CA $144
CA $162 total
includes taxes & fees
Jun 9 - Jun 10
Drury Inn & Suites Gainesville
Exterior

Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands
2.5 star property
Gainesville
8.8 out of 10, Excellent, (1,206 reviews)
"We had a great stay! Breakfast was good and the staff were very nice. "
United States
Christina
The price is CA $111
CA $133 total
includes taxes & fees
Jun 9 - Jun 10
Sleep Inn & Suites University/Shands
Premium bedding, desk, blackout drapes, soundproofing

Palms Garden Inn

Palms Garden Inn
2.0 star property
Lake City
7.4 out of 10, Good, (606 reviews)
"Staff nice and helpful"
United States
Drew
The price is CA $89
CA $100 total
includes taxes & fees
May 14 - May 15
Palms Garden Inn
Exterior

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
Alachua
9.4 out of 10, Exceptional, (1,013 reviews)
"Great stay, nice area"
United States
Jennifer
The price is CA $140
CA $157 total
includes taxes & fees
May 24 - May 25
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Reception

Best Western Gateway Grand

Best Western Gateway Grand
3.0 star property
Gainesville
8.6 out of 10, Excellent, (1,472 reviews)
"The staff was very helpful with checking and out and shuttle to the airport"
United States
Alesa
The price is CA $127
CA $143 total
includes taxes & fees
May 18 - May 19
Best Western Gateway Grand
Breakfast area

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
Alachua
9.4 out of 10, Exceptional, (510 reviews)
"Room was very clean, breakfast was awesome, everything was good."
United States
James
The price is CA $127
CA $143 total
includes taxes & fees
May 24 - May 25
Hampton Inn & Suites Alachua I-75
Exterior

Hampton Inn Gainesville

Hampton Inn Gainesville
2.5 star property
Gainesville
8.8 out of 10, Excellent, (1,008 reviews)
"Love this hotel and the staff. "
United States
Tamara
The price is CA $129
CA $145 total
includes taxes & fees
May 24 - May 25
Hampton Inn Gainesville
Exterior

Comfort Inn University

Comfort Inn University
2.5 star property
Gainesville
8.4 out of 10, Very good, (1,061 reviews)
"Clean and staff was amazing the breakfast was perfect"
United States
Christina
The price is CA $111
CA $133 total
includes taxes & fees
May 26 - May 27
Comfort Inn University
Lobby sitting area

HOM Hotel Gainesville, SureStay Collection by Best Western

HOM Hotel Gainesville, SureStay Collection by Best Western
2.5 star property
Gainesville
8.6 out of 10, Excellent, (1,927 reviews)
"Clean rooms, good breakfast would stay here again "
United States
Seana
The price is CA $117
CA $132 total
includes taxes & fees
May 13 - May 14
HOM Hotel Gainesville, SureStay Collection by Best Western
Lobby

SpringHill Suites by Marriott Gainesville

SpringHill Suites by Marriott Gainesville
3.0 star property
Gainesville
8.8 out of 10, Excellent, (1,007 reviews)
"Hotel was great, friendly staff. "
United States
AnaMaria
The price is CA $127
CA $143 total
includes taxes & fees
May 24 - May 25
SpringHill Suites by Marriott Gainesville
Meeting facility

Hilton University of Florida Conference Center Gainesville

Hilton University of Florida Conference Center Gainesville
3.5 star property
Gainesville
8.4 out of 10, Very good, (1,017 reviews)
"A very good stay at a clean hotel."
United States
Kenneth
The price is CA $156
CA $175 total
includes taxes & fees
May 27 - May 28
Hilton University of Florida Conference Center Gainesville
Lobby

Fairfield Inn & Suites by Marriott Gainesville I-75

Fairfield Inn & Suites by Marriott Gainesville I-75
3.0 star property
Gainesville
9.6 out of 10, Exceptional, (1,008 reviews)
"Very clean and staff was very friendly. "
United States
Lorty
The price is CA $163
CA $183 total
includes taxes & fees
May 17 - May 18
Fairfield Inn & Suites by Marriott Gainesville I-75
Free daily full breakfast

Quality Inn Alachua - Gainesville Area

Quality Inn Alachua - Gainesville Area
2.5 star property
Alachua
7.2 out of 10, Good, (1,015 reviews)
"Solid hotel for the price"
United States
Michael
The price is CA $102
CA $114 total
includes taxes & fees
Jun 2 - Jun 3
Quality Inn Alachua - Gainesville Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santa Fe Hotel Reviews

Recent Reviews in Santa Fe

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

10/10 Excellent
"Todo muy rico"
Maria 1-night trip
Posted 2 hours ago
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

More cheap stays in Santa Fe

Red Roof Inn PLUS+ Gainesville

Red Roof Inn PLUS+ Gainesville

3500 Southwest 42nd St Gainesville FL
The price is CA $89 per night from Jun 1 to Jun 2
CA $89
CA $100 total
Jun 1 - Jun 2
includes taxes & fees
7.4/10 Good! (1,298 reviews)

Hotels in Santa Fe with star rating

Frequently asked questions

What's the best place for a stay in Santa Fe?
Located 18.6 mi (29.9 km) from the heart of Santa Fe, Country Inn & Suites by Radisson, Gainesville, FL is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are Sleep Inn & Suites University/Shands and Drury Inn & Suites Gainesville. See all available top hotels, or vacation rentals in Santa Fe.
What are some of the best vacation rentals in Santa Fe?
Family-Friendly Gainesville Home - Walk to UF - Pool + Sleeps 16: This vacation home rental outside of Santa Fe offers an outdoor pool, a fireplace, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. It offers a balcony, a garden, and a selection of games so you can immerse yourself in your vacation. See all vacation rentals in Santa Fe.
If I need to cancel my hotel reservation in Santa Fe, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled before the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Fe.
What is staying in Santa Fe like?
Travelers to Santa Fe will find plenty to explore and enjoy. There are 781 hotels and other accommodations in the surrounding area. Find out more about Santa Fe.
What are the top places to visit in Santa Fe?
Places to visit in the wider area include O'Leno State Park, San Felasco Hammock Preserve State Park, and Camp Kulaqua Conservation Easement. You'll also find Devil's Milhopper Geological State Park and Gainesville Raceway in the area. Check out what more to see and do in Expedia's Santa Fe guide.
What's the seasonal weather like in Santa Fe?
The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 59°F. The rainiest months in Santa Fe are August, June, July, and September, with each month seeing an average of 7 inches of rainfall.

Explore a world of travel with Expedia