Title: 10 Best Hotels in Santa Fé, Guarani das Missões for 2026 | Expedia.ca [Vacation Rentals in Guarani das Missões](https://expedia.ca/Guarani-Das-Missoes-Vacation-Rentals.d553248634664609476.Travel-Guide-VacationRentals)[Santa Fé Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Fe.d553248635318393892.Car-Rental-Guide)[Santa Fé Vacations](https://expedia.ca/Santa-Fe.d553248635318393892.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Hotels in Santa Fé, Guarani das Missões - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 11 - Dec 12](https://www.expedia.ca/Hotel-Search?regionId=553248635318393892&startDate=2025-12-11&endDate=2025-12-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 12 - Dec 13](https://www.expedia.ca/Hotel-Search?regionId=553248635318393892&startDate=2025-12-12&endDate=2025-12-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=553248635318393892&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=553248635318393892&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Where to stay in Santa Fé Find the best Santa Fé areas and neighborhoods for the activities you enjoy most. - Vila Esperança - Santa Tereza - Pampa - Guarani das Missões Centro [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635318435509) ![Vila Esperança map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:x_wjDvi_lIa%40%7DGeB%7DFoBuBsEVcAfCa%40my%40bN%5Br%40zj%40h%40THdF%7BA%40KlAnBpFr%40bIUfA_AT&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=TwqYRio2heDn5IRwFrukX0ueFMQ=) ### Vila Esperança [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635318435509) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635318411795) ![Santa Tereza map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:r%60wjDrr%7EkIIeFi%40Us%40%7Bj%40lz%40kAAls%40cw%40t%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=zwLNPISpLGAE7kPVVwzkIH_-n4U=) ### Santa Tereza [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635318411795) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635318379875) ![Pampa map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7CrwjDno%60lIuECM_Cv%40kJpLICmFxd%40y%40_BzTwi%40PCrA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=ozGuPpexvBxOxc2_ZgjVzin21uc=) ### Pampa [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635318379875) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635318324713) ![Guarani das Missões Centro map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:flwjDjo%60lIsYKdFuF%60HaRaAoI%7E%40UTgAs%40cIoBqFJmA%7Ey%40w%40%40ms%40rRDGjRkJjeAyd%40x%40BlFqLHw%40jJL%7EB&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=4yVzzb2NDVcgxY50AT-u2p4qy7E=) ### Guarani das Missões Centro [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635318324713) ## Top Santa Fé Hotel Reviews ## Frequently asked questions ### What is Santa Fé like? ### If I need to cancel my hotel reservation in Santa Fé, will I receive a refund? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [Alecrim Hotels ](https://www.expedia.ca/Alecrim-Hotels.d553248634664577739.Travel-Guide-Hotels) - [Augusto Pestana Hotels ](https://www.expedia.ca/Augusto-Pestana-Hotels.d6352044.Travel-Guide-Hotels) - [Boa Vista do Burica Hotels ](https://www.expedia.ca/Boa-Vista-Do-Burica-Hotels.d6352016.Travel-Guide-Hotels) - [Lgbt Friendly Hotels in Boqueirão ](https://www.expedia.ca/Boqueirao-Passo-Fundo-Hotels-LGBT-Friendly-Hotel.0-n553248635318477682-0-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - [Caibaté Hotels ](https://www.expedia.ca/Caibate-Hotels.d553248634664619721.Travel-Guide-Hotels) - [Cândido Godói Hotels ](https://www.expedia.ca/Candido-Godoi-Hotels.d553248634664564911.Travel-Guide-Hotels) - [Cerro Largo Hotels ](https://www.expedia.ca/Cerro-Largo-Hotels.d6352387.Travel-Guide-Hotels) - [Doutor Maurício Cardoso Hotels ](https://www.expedia.ca/Doutor-Mauricio-Cardoso-Hotels.d553248634664619751.Travel-Guide-Hotels) - [Duque de Caxias Hotels ](https://www.expedia.ca/Duque-De-Caxias-Sao-Luiz-Gonzaga-Hotels.0-n553248635318335528-0.Travel-Guide-Filter-Hotels) - [Girua Hotels ](https://www.expedia.ca/Girua-Hotels.d6351759.Travel-Guide-Hotels) - [Herval Hotels ](https://www.expedia.ca/Herval-Ijui-Hotels.0-n553248635318369481-0.Travel-Guide-Filter-Hotels) - [Horizontina Hotels ](https://www.expedia.ca/Horizontina-Hotels.d6352014.Travel-Guide-Hotels) - [Ijui Hotels ](https://www.expedia.ca/Ijui-Hotels.d6351760.Travel-Guide-Hotels) - [Industrial Hotels ](https://www.expedia.ca/Industrial-Ijui-Hotels.0-n553248635318313950-0.Travel-Guide-Filter-Hotels) - [Jardim Hotels ](https://www.expedia.ca/Jardim-Ijui-Hotels.0-n553248635318261924-0.Travel-Guide-Filter-Hotels) - [Modelo Hotels ](https://www.expedia.ca/Modelo-Ijui-Hotels.0-n553248635318392574-0.Travel-Guide-Filter-Hotels) - [Operário Hotels ](https://www.expedia.ca/Operario-Catuipe-Hotels.0-n553248635318411391-0.Travel-Guide-Filter-Hotels) - [Pindorama Hotels ](https://www.expedia.ca/Pindorama-Ijui-Hotels.0-n553248635318443933-0.Travel-Guide-Filter-Hotels) - 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[São Cristovão Hotels ](https://www.expedia.ca/Sao-Cristovao-Catuipe-Hotels.0-n553248635318439611-0.Travel-Guide-Filter-Hotels) - [Sao Luiz Gonzaga Hotels ](https://www.expedia.ca/Sao-Luiz-Gonzaga-Hotels.d6352010.Travel-Guide-Hotels) - [Sao Miguel das Missoes Hotels ](https://www.expedia.ca/Sao-Miguel-Das-Missoes-Hotels.d6205194.Travel-Guide-Hotels) - [São Paulo das Missões Hotels ](https://www.expedia.ca/Sao-Paulo-Das-Missoes-Hotels.d553248634664612230.Travel-Guide-Hotels) - [São Valério do Sul Hotels ](https://www.expedia.ca/Sao-Valerio-Do-Sul-Hotels.d553248634664632436.Travel-Guide-Hotels) - [Sol Nascente Hotels ](https://www.expedia.ca/Sol-Nascente-Ijui-Hotels.0-n553248635318417308-0.Travel-Guide-Filter-Hotels) - [Tres de Maio Hotels ](https://www.expedia.ca/Tres-De-Maio-Hotels.d3000379157.Travel-Guide-Hotels) - [Flights to Encantado ](https://www.expedia.ca/Cheap-Flights-To-Encantado.d178485.Travel-Guide-Flights) - [Flights to Lauro Kurtz ](https://www.expedia.ca/Cheap-Flights-To-Lauro-Kurtz.d6031056.Travel-Guide-Flights) - [Flights to Santa Maria ](https://www.expedia.ca/Cheap-Flights-To-Santa-Maria.d2991.Travel-Guide-Flights) - [Flights from Andros Town (ASD) to Santa Maria (RIA) ](https://www.expedia.ca/lp/flights/asd/ria/andros-town-to-santa-maria) - [Flights from São Paulo (GRU) to Santo Angelo (GEL) ](https://www.expedia.ca/lp/flights/gru/gel/sao-paulo-to-santo-angelo) - [Flights from São Paulo (GRU) to Passo Fundo (PFB) ](https://www.expedia.ca/lp/flights/gru/pfb/sao-paulo-to-passo-fundo) - [Flights from São Paulo (GRU) to Santa Maria (RIA) ](https://www.expedia.ca/lp/flights/gru/ria/sao-paulo-to-santa-maria) - [Flights from Kashi (KHG) to Santa Maria (RIA) ](https://www.expedia.ca/lp/flights/khg/ria/kashi-to-santa-maria) - [Flights from Calgary (YYC) to Santa Maria (RIA) ](https://www.expedia.ca/lp/flights/yyc/ria/calgary-to-santa-maria) - [Flights from Toronto (YYZ) to Santa Maria (RIA) ](https://www.expedia.ca/lp/flights/yyz/ria/toronto-to-santa-maria) - [Condor Vacations ](https://www.expedia.ca/Condor.d553248634664619376.Destination-Travel-Guides) - [Encantado Vacations ](https://www.expedia.ca/Encantado.d178485.Destination-Travel-Guides) - [Visit Encantado ](https://www.expedia.ca/Encantado.dx178485) - [Visit Horizontina ](https://www.expedia.ca/Horizontina.dx6352014) - [Visit Canudinho ](https://www.expedia.ca/Machadinho-Canudinho.dx553248635318328677) - [Visit Mucum ](https://www.expedia.ca/Mucum.dx6352125) - [Visit Passo Fundo ](https://www.expedia.ca/Passo-Fundo.dx2772) - [Santo Cristo Vacations ](https://www.expedia.ca/Santo-Cristo.d6352012.Destination-Travel-Guides) - [Visit Santo Expedito do Sul ](https://www.expedia.ca/Santo-Expedito-Do-Sul.dx553248634664633410) - [Visit São Borja ](https://www.expedia.ca/Sao-Borja.dx6352007) - [Visit Sao Gabriel ](https://www.expedia.ca/Sao-Gabriel.dx6351764) - [Visit Sao Sepe ](https://www.expedia.ca/Sao-Sepe.dx6352077) - [Visit Sertão ](https://www.expedia.ca/Sertao.dx553248634664616904) - [Visit Tapera ](https://www.expedia.ca/Tapera.dx6353379) - [Car rental Candelaria ](https://www.expedia.ca/Car-Rentals-In-Candelaria.d6352390.Car-Rental-Guide) - [Car rentals near Country ](https://www.expedia.ca/Car-Rentals-In-Country.d553248635318489703.Car-Rental-Guide) - [Car rentals near Fátima ](https://www.expedia.ca/Car-Rentals-In-Fatima.d553248635318361542.Car-Rental-Guide) - [Car rentals near Gare Park ](https://www.expedia.ca/Car-Rentals-In-Gare-Park.d6223109.Car-Rental-Guide) - [Car rentals near Our Lady Of Fatima Monument ](https://www.expedia.ca/Car-Rentals-In-Our-Lady-Of-Fatima-Monument.d553248621562279830.Car-Rental-Guide) - [Car rentals near Santa Lúcia ](https://www.expedia.ca/Car-Rentals-In-Santa-Lucia.d553248635318492928.Car-Rental-Guide) - [Itaqui Vacation Rentals ](https://www.expedia.ca/Itaqui-Vacation-Rentals.d6352005.Travel-Guide-VacationRentals) - [Book Hotels in Santa Fé on Expedia.com.br ](https://www.expedia.com.br/Santa-Fe-Guarani-Das-Missoes-Hoteis.0-n553248635318393892-0.Guia-de-Viagem-Filtrar-Hoteis)