Title: 10 Best Hotels in Santa Cruz, Santo Antônio de Pádua for 2025 | Expedia.ca [Vacation Rentals in Santo Antônio de Pádua](https://expedia.ca/Santo-Antonio-De-Padua-Vacation-Rentals.d553248634664619176.Travel-Guide-VacationRentals)[Santa Cruz Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Cruz.d553248635318504840.Car-Rental-Guide)[Santa Cruz Vacations](https://expedia.ca/Santa-Cruz.d553248635318504840.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Hotels in Santa Cruz, Santo Antônio de Pádua ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 6 - Oct 7](https://www.expedia.ca/Hotel-Search?regionId=553248635318504840&startDate=2025-10-06&endDate=2025-10-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 7 - Oct 8](https://www.expedia.ca/Hotel-Search?regionId=553248635318504840&startDate=2025-10-07&endDate=2025-10-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=553248635318504840&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635318504840&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Santa Cruz hotels and places to stay ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Santo-Antonio-De-Padua-Hotels.0-n553248635318504840-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Santo-Antonio-De-Padua-Hotels.0-n553248635318504840-0.Travel-Guide-Filter-Hotels) ## Where to stay in Santa Cruz Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. - Ibitiguaçu [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635318335384) ![Ibitiguaçu map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7CxfbC%60_z_G%7BIoKfEmFlOfFyJtK&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=1TAt5K6zIviK6WJGdxEyDyMd9sE=) ### Ibitiguaçu [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635318335384) ## Top Santa Cruz Hotel Reviews ## Explore a world of travel with Expedia - More ways to book - [Book Hotels in Santa Cruz on Expedia.com.br](https://www.expedia.com.br/Santa-Cruz-Santo-Antonio-De-Padua-Hoteis.0-n553248635318504840-0.Guia-de-Viagem-Filtrar-Hoteis) - Explore a world of travel with Expedia ### More ways to book - [Book Hotels in Santa Cruz on Expedia.com.br](https://www.expedia.com.br/Santa-Cruz-Santo-Antonio-De-Padua-Hoteis.0-n553248635318504840-0.Guia-de-Viagem-Filtrar-Hoteis)