Title: Book the Best BUSINESS Hotels in Santa Clarita in 2026 | Expedia.ca [Santa Clarita Travel Guide](https://expedia.ca/Santa-Clarita.dx9878)[Hotels in Santa Clarita](https://expedia.ca/Santa-Clarita-Hotels.d9878.Travel-Guide-Hotels)[Vacation Rentals in Santa Clarita](https://expedia.ca/Santa-Clarita-Vacation-Rentals.d9878.Travel-Guide-VacationRentals)[Flights to Santa Clarita](https://expedia.ca/Cheap-Flights-To-Santa-Clarita.d9878.Travel-Guide-Flights)[Santa Clarita Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Clarita.d9878.Car-Rental-Guide)[Santa Clarita Vacation Packages](https://expedia.ca/Santa-Clarita.d9878.Destination-Travel-Guides) ![Vasquez Rocks Natural Area Park is a 932-acre park located in the Sierra Pelona Mountains, in northern Los Angeles County, California. ](https://images.trvl-media.com/place/9878/fb8bc6d4-261e-4d1f-b808-910aa1a88ffc.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Pon Xayavong Photography ![](https://images.trvl-media.com/place/9878/fb8bc6d4-261e-4d1f-b808-910aa1a88ffc.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Clarita Business Hotels Tonight [Jan 25 - Jan 26](https://www.expedia.ca/Hotel-Search?regionId=9878&startDate=2026-01-25&endDate=2026-01-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Jan 26 - Jan 27](https://www.expedia.ca/Hotel-Search?regionId=9878&startDate=2026-01-26&endDate=2026-01-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=9878&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) In two weeks [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=9878&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Santa Clarita business-friendly hotels ![Lounge](https://images.trvl-media.com/lodging/12000000/11010000/11005400/11005321/2f3ab7d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/12000000/11010000/11005400/11005321/1c2d1748.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11010000/11005400/11005321/07700e09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/12000000/11010000/11005400/11005321/8d1ffb33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Garden Lancaster CA [](https://www.expedia.ca/Lancaster-Hotels-Wyndham-Garden-Lancaster-CA.h11005321.Hotel-Information) Lancaster 9.0/10 Wonderful (1,010 reviews) "Great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leonel CA $139 CA $153 total includes taxes & fees Jan 29 - Jan 30 [](https://www.expedia.ca/Lancaster-Hotels-Wyndham-Garden-Lancaster-CA.h11005321.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1210000/1209300/1209293/b274eb8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1210000/1209300/1209293/5675aba7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Two queen beds non smoking](https://images.trvl-media.com/lodging/2000000/1210000/1209300/1209293/w3837h2561x3y0-841e0126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1210000/1209300/1209293/10e5326a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Palmdale [](https://www.expedia.ca/Lancaster-Hotels-Hampton-Inn-Suites-Palmdale.h1209293.Hotel-Information) Palmdale 8.4/10 Very good (1,001 reviews) "Great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) FA'AFETAI CA $104 CA $120 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Lancaster-Hotels-Hampton-Inn-Suites-Palmdale.h1209293.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/2800/2702/01d37155.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed](https://images.trvl-media.com/lodging/1000000/10000/2800/2702/e7226281.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dinner served](https://images.trvl-media.com/lodging/1000000/10000/2800/2702/5b952352.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2800/2702/f46936e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Palmdale, CA [](https://www.expedia.ca/Lancaster-Hotels-Ramada-By-Wyndham-Palmdale.h2702.Hotel-Information) Palmdale 9.2/10 Wonderful (794 reviews) "Property was clean, staff was awesome and check-in was easy" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hernan CA $118 CA $133 total includes taxes & fees Feb 21 - Feb 22 [](https://www.expedia.ca/Lancaster-Hotels-Ramada-By-Wyndham-Palmdale.h2702.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1560000/1550200/1550158/9847c5b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1560000/1550200/1550158/637112b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/2000000/1560000/1550200/1550158/96e24986.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/2000000/1560000/1550200/1550158/b5be4c8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Santa Clarita - Valencia [](https://www.expedia.ca/Los-Angeles-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Santa-Clarita-Valencia.h1550158.Hotel-Information) Stevenson Ranch 9.2/10 Wonderful (1,982 reviews) "Clean room, breakfast a lot to choose from,friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Miguel CA $171 CA $192 total includes taxes & fees Jan 27 - Jan 28 [](https://www.expedia.ca/Los-Angeles-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Santa-Clarita-Valencia.h1550158.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/83000000/82500000/82490600/82490563/536b77ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/83000000/82500000/82490600/82490563/ee037979.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/83000000/82500000/82490600/82490563/0efc4b8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/83000000/82500000/82490600/82490563/3972c3d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Lancaster Palmdale [](https://www.expedia.ca/Lancaster-Hotels-Fairfield-Inn-Suites-By-Marriott-Lancaster-Palmdale.h82490563.Hotel-Information) Lancaster 9.4/10 Exceptional (701 reviews) "Have stayed here for the 2nd time and it has been great! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maria CA $159 CA $176 total includes taxes & fees Jan 29 - Jan 30 [](https://www.expedia.ca/Lancaster-Hotels-Fairfield-Inn-Suites-By-Marriott-Lancaster-Palmdale.h82490563.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/19000000/18560000/18553000/18552917/4ae6cb20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18560000/18553000/18552917/7bf979d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/19000000/18560000/18553000/18552917/d282ef8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/19000000/18560000/18553000/18552917/7a4ec1e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Element Palmdale [](https://www.expedia.ca/Lancaster-Hotels-Element-Palmdale.h18552917.Hotel-Information) Palmdale 9.2/10 Wonderful (652 reviews) "This hotel was very convenient and lots of things around to do. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Denise CA $130 CA $146 total includes taxes & fees Jan 30 - Jan 31 [](https://www.expedia.ca/Lancaster-Hotels-Element-Palmdale.h18552917.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/28500/28453/8a1e47db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/28500/28453/31671696.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/28500/28453/a7c555d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/30000/28500/28453/f103029a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Oxnard Inn Lancaster [](https://www.expedia.ca/Lancaster-Hotels-Oxford-Suites-Lancaster.h28453.Hotel-Information) Lancaster 8.8/10 Excellent (1,005 reviews) "I enjoyed my stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anthony CA $126 CA $139 total includes taxes & fees Feb 24 - Feb 25 [](https://www.expedia.ca/Lancaster-Hotels-Oxford-Suites-Lancaster.h28453.Hotel-Information) ![One King Deluxe Room](https://images.trvl-media.com/lodging/1000000/90000/85000/84912/4950c9a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Two Queen Deluxe Room](https://images.trvl-media.com/lodging/1000000/90000/85000/84912/d59bce06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Queen Room with Two Queen Beds | Bathroom](https://images.trvl-media.com/lodging/1000000/90000/85000/84912/a51b0092.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/90000/85000/84912/6d78483d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Santa Clarita Motel [](https://www.expedia.ca/Los-Angeles-Hotels-Santa-Clarita-Motel.h84912.Hotel-Information) Newhall 8.8/10 Excellent (1,012 reviews) "I like staying at Santa Clarita motel every time I visit the area. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Arqui CA $105 CA $119 total includes taxes & fees Jan 27 - Jan 28 [](https://www.expedia.ca/Los-Angeles-Hotels-Santa-Clarita-Motel.h84912.Hotel-Information) ![Banquet hall](https://images.trvl-media.com/lodging/1000000/30000/23000/22953/05da0425.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/1000000/30000/23000/22953/5e8d767f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/23000/22953/07be5002.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, 1 King Bed](https://images.trvl-media.com/lodging/1000000/30000/23000/22953/37540cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Vista Hotel [](https://www.expedia.ca/Simi-Valley-Hotels-Grand-Vista-Hotel.h22953.Hotel-Information) Simi Valley 8.2/10 Very good (1,509 reviews) "Everyone was super polite and helpful" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Atinuke CA $122 CA $137 total includes taxes & fees Jan 27 - Jan 28 [](https://www.expedia.ca/Simi-Valley-Hotels-Grand-Vista-Hotel.h22953.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/55000000/54090000/54081600/54081573/789e28c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/55000000/54090000/54081600/54081573/c53d1adf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/55000000/54090000/54081600/54081573/e1f92b50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/55000000/54090000/54081600/54081573/6108abdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Valencia - Santa Clarita by IHG [](https://www.expedia.ca/Los-Angeles-Hotels-Holiday-Inn-Express-Suites-Valencia-Santa-Clarita.h54081573.Hotel-Information) Valencia 9.4/10 Exceptional (1,011 reviews) "One of the nicer hires we’ve stayed at, definitely coming back " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mercedes CA $167 CA $188 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Los-Angeles-Hotels-Holiday-Inn-Express-Suites-Valencia-Santa-Clarita.h54081573.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-09&endDate=2026-02-10®ionId=9878&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Santa Clarita Hotel Reviews ![The Garland](https://images.trvl-media.com/lodging/1000000/20000/16400/16395/d7742937_y.jpg) ### The Garland 10/10 Excellent "The staff were attentive when we needed something and the room service was quick. Great ambiance " [](https://expedia.ca/Los-Angeles-Hotels-The-Garland.h16395.Hotel-Information) ![Los Angeles Marriott Burbank Airport](https://images.trvl-media.com/lodging/1000000/10000/5900/5842/059d1ed7_y.jpg) ### Los Angeles Marriott Burbank Airport 10/10 Excellent "Great room, great location, great outdoor bar." [](https://expedia.ca/Los-Angeles-Hotels-Los-Angeles-Marriott-Burbank-Airport.h5842.Hotel-Information) ![Hotel Burbank](https://images.trvl-media.com/lodging/1000000/10000/7500/7457/7ff5ade4_y.jpg) ### Hotel Burbank 10/10 Excellent "Well located and priced hotel for a quick overnight near Burbank airport. Friendly staff and comfortable rooms with a great view from high floors and the elevator" [](https://expedia.ca/Los-Angeles-Hotels-Hotel-Burbank.h7457.Hotel-Information) ![The Tangerine - A Burbank Hotel](https://images.trvl-media.com/lodging/4000000/3520000/3510900/3510869/14c3f3d4_y.jpg) ### The Tangerine - A Burbank Hotel 10/10 Excellent "A cosy, clean, and well-maintained stay. The staff is polite, approachable, and happy to accommodate requests within reason. The continental breakfast is a definite plus. Would highly recommend and would love to revisit." [](https://expedia.ca/Los-Angeles-Hotels-The-Tangerine.h3510869.Hotel-Information) ![Best Western Plus Carriage Inn](https://images.trvl-media.com/lodging/1000000/10000/4800/4753/w5760h3835x0y5-42244a68_y.jpg) ### Best Western Plus Carriage Inn 10/10 Excellent "Very accommodating... We asked for a quiet room and they gave us a great room. Allowing us an early nights sleep. " [](https://expedia.ca/Los-Angeles-Hotels-Best-Western-Plus-Carriage-Inn.h4753.Hotel-Information) ![Sheraton Universal Hotel](https://images.trvl-media.com/lodging/1000000/20000/10100/10003/c6cd1373_y.jpg) ### Sheraton Universal Hotel 10/10 Excellent "Lovely, clean and spacious hotel right next to the park. Absolutely loved staying here and would definitely book again for future visits. " [](https://expedia.ca/Los-Angeles-Hotels-Sheraton-Universal-Hotel.h10003.Hotel-Information) ![Hilton Garden Inn Calabasas](https://images.trvl-media.com/lodging/1000000/890000/889300/889222/6b3ea089_y.jpg) ### Hilton Garden Inn Calabasas 10/10 Excellent "Shower curtain too short, small flood. Toilet 12 inches off the floor, no air vent, in thr bathroom. Stiff beds, and the TV signal went in and out all night. Other than that it was very nice..." [](https://expedia.ca/Los-Angeles-Hotels-Hilton-Garden-Inn-Calabasas.h889222.Hotel-Information) ![The Anza - A Calabasas Hotel](https://images.trvl-media.com/lodging/1000000/10000/4000/3917/80cbfa59_y.jpg) ### The Anza - A Calabasas Hotel 10/10 Excellent "Very nice front desk clerk. Great customer service and clean room." [](https://expedia.ca/Los-Angeles-Hotels-The-Anza-A-Calabasas-Hotel.h3917.Hotel-Information) ![Hilton Los Angeles/Universal City](https://images.trvl-media.com/lodging/1000000/30000/20700/20611/633a235c_y.jpg) ### Hilton Los Angeles/Universal City 10/10 Excellent "All the staff were phenomenal. Hugely efficient and hospitable. Danny in particular was incredibly warm and helpful, nothing was too much trouble when helping me with my suitcases. 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