Santa Clara Vacation Rentals

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Santa Clara vacation rentals

Enchanting Love Nest la Fortuna. It's a haven of beauty and relaxation.

Enchanting Love Nest la Fortuna. It's a haven of beauty and relaxation.
Altos del Maria
The price is CA $188
CA $289 total
includes taxes & fees
Apr 6 - Apr 7
Enchanting Love Nest la Fortuna. It's a haven of beauty and relaxation.

Cozy 1-bedroom apartment in adorable Las Lajas with AC

Cozy 1-bedroom apartment in adorable Las Lajas with AC
Las Lajas
6.0 out of 10, (1 review)
"Took some cleaning, sparse utensils and towels, refrigerator could use a good defrosting. "
United States
Jeff B.
The price is CA $126
CA $181 total
includes taxes & fees
Apr 6 - Apr 7
Cozy 1-bedroom apartment in adorable Las Lajas with AC

Lovely condo with beach, mountain and pool view.

Lovely condo with beach, mountain and pool view.
Nueva Gorgona
10.0 out of 10, Exceptional, (12 reviews)
"The property was a great place to settle in and call home for a week."
Canada
Chad B.
The price is CA $126
CA $202 total
includes taxes & fees
Apr 7 - Apr 8
Lovely condo with beach, mountain and pool view.

Villa de Montana en Altos del Maria

Villa de Montana en Altos del Maria
sora , Altos del Maria
The price is CA $351
CA $439 total
includes taxes & fees
Apr 16 - Apr 17
Villa de Montana en Altos del Maria

Romantic and cozy apartment in tropical villa w/ mountain and flowers view.

Romantic and cozy apartment in tropical villa w/ mountain and flowers view.
Altos del Maria
10.0 out of 10, Exceptional, (1 review)
"As advertised. Quiet, beautiful, and relaxing. Loved the pool"
United States
Donald R.
The price is CA $307
CA $414 total
includes taxes & fees
Apr 6 - Apr 7
Romantic and cozy apartment in tropical villa w/ mountain and flowers view.

Riomar Luxurious Beachfront Aptartment, 3 bedroom

Riomar Luxurious Beachfront Aptartment, 3 bedroom
San Carlos
The price is CA $314
CA $531 total
includes taxes & fees
Apr 6 - Apr 7
Riomar Luxurious Beachfront Aptartment, 3 bedroom

Cabanas Potosi, El Valle de Anton, Panama Birders-Nature Lovers-Waterfalls-ETC

Cabanas Potosi, El Valle de Anton, Panama Birders-Nature Lovers-Waterfalls-ETC
El Valle de Anton
9.6 out of 10, Exceptional, (17 reviews)
"We had a fantastic stay. Our cabin was very comfortable in clean. Our host Dennis was most friendly and helpful at all times. Truly enjoyed the beautiful, botanical grounds and the variety of birds we were able to view on the property. Very well maintained. We highly recommend a visit!!"
United States
Tracy B R.
The price is CA $110
CA $149 total
includes taxes & fees
Apr 16 - Apr 17
Cabanas Potosi, El Valle de Anton, Panama Birders-Nature Lovers-Waterfalls-ETC

PLAYA BLANCA GOLF and BEACH VILLA

PLAYA BLANCA GOLF and BEACH VILLA
3.5 star property
Rio Hato
The price is CA $321
CA $388 total
includes taxes & fees
May 2 - May 3
PLAYA BLANCA GOLF and BEACH VILLA

Altavida Lodge · Private Studio with Pool · N6

Altavida Lodge · Private Studio with Pool · N6
Valle de Anton
Altavida Lodge · Private Studio with Pool · N6

★ Quinta Pavo Real - The Magic Tree House

★ Quinta Pavo Real - The Magic Tree House
Quinta Pavo Real
8.0 out of 10, Very good, (1 review)
"Hay muchos animales tipo zoológico que andan libres por la propiedad lo que te transporta a otro lugar y te ayuda a desconectar "
Mexico
Franklin
★ Quinta Pavo Real - The Magic Tree House

Cozy Condo con piscina en Playa Coronado/Cozy Condo with pool in Coronado

Cozy Condo con piscina en Playa Coronado/Cozy Condo with pool in Coronado
Las Lajas
7.8 out of 10, Good, (10 reviews)
"Everyone was very nice, the pool was wonderful, it is close to restaurants and shopping. The kitchen was a little to small to really cook, but we had a great time for the week we were there."
United States
Sherry P.
The price is CA $88
CA $158 total
includes taxes & fees
Apr 19 - Apr 20
Cozy Condo con piscina en Playa Coronado/Cozy Condo with pool in Coronado

Linda Vista, Enorme Terraza, Barbacoa y Piscina. Disfruta del Grato Ambiente

Linda Vista, Enorme Terraza, Barbacoa y Piscina. Disfruta del Grato Ambiente
Provincia de Panamá Oeste
The price is CA $383
CA $476 total
includes taxes & fees
Apr 6 - Apr 7
Linda Vista, Enorme Terraza, Barbacoa y Piscina. Disfruta del Grato Ambiente

Apartment in Playa Blanca, in front of the sea. Swimming Pool and Direct Access to the Beach

Apartment in Playa Blanca, in front of the sea. Swimming Pool and Direct Access to the Beach
Coclé
9.0 out of 10, Wonderful, (2 reviews)
"Neidy was very easy to work with and was flexible with the check in time since no one was renting the day before our arrival. "
United States
Sean T.
The price is CA $338
CA $438 total
includes taxes & fees
Apr 7 - Apr 8
Apartment in Playa Blanca, in front of the sea. Swimming Pool and Direct Access to the Beach

COUNTRY HOUSE

COUNTRY HOUSE
El Valle de Antón
The price is CA $342
CA $389 total
includes taxes & fees
Apr 6 - Apr 7
COUNTRY HOUSE

Coronado Hideaway with Private Pool

Coronado Hideaway with Private Pool
2.0 star property
Las Lajas
The price is CA $114
CA $167 total
includes taxes & fees
Apr 12 - Apr 13
Coronado Hideaway with Private Pool

Studio

Studio
Río Hato
10.0 out of 10, Exceptional, (1 review)
"Todo bien"
United States
Irving R.
The price is CA $153
CA $238 total
includes taxes & fees
Apr 6 - Apr 7
Studio

Spacious mountain villa with 5 bedrooms and brand new AC

Spacious mountain villa with 5 bedrooms and brand new AC
Anton Valley
10.0 out of 10, Exceptional, (4 reviews)
"What a perfect location, an immaculate property, and a genuinely gracious host! This home has all of the amenities to make an El Valle visit warm, welcoming, and memorable. Only good and positive things to say about our stay! Thank you!!"
United States
Robert P.
The price is CA $300
CA $407 total
includes taxes & fees
Apr 6 - Apr 7
Spacious mountain villa with 5 bedrooms and brand new AC

Modern House with Heated Pool and Great Views

Modern House with Heated Pool and Great Views
Chame, Sora
9.0 out of 10, Wonderful, (7 reviews)
"The views and pool were amazing. It did lack some things like sufficient dishes and instructions for the home. Overall, it is a lovely property and the neighborhood is amazing."
United States
Lisa W.
The price is CA $346
CA $432 total
includes taxes & fees
Apr 20 - Apr 21
Modern House with Heated Pool and Great Views

Modern Studio for 4 Guests Valle de Antón A1

Modern Studio for 4 Guests Valle de Antón A1
Valle de Anton
Modern Studio for 4 Guests Valle de Antón A1

Panama's Paradise - Playa Blanca - Ocean & Pool View - Huge Saltwater Pool

Panama's Paradise - Playa Blanca - Ocean & Pool View - Huge Saltwater Pool
Rio Hato
10.0 out of 10, Exceptional, (1 review)
The price is CA $188
CA $293 total
includes taxes & fees
Apr 14 - Apr 15
Panama's Paradise - Playa Blanca - Ocean & Pool View - Huge Saltwater Pool
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Santa Clara Hotel Reviews

Find out more about Santa Clara

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Santa Clara. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find a vacation rental in Santa Clara?

Yes, we offer vacation rentals close to popular sights in Santa Clara, or you can go with a secluded option if you want a relaxing place to stay. Santa Clara is known for its beaches.

What are some of the best vacation rentals in Santa Clara?

Chic 1-bedroom with WiFi and AC in enchanting Río Hato: Visitors like this Santa Clara vacation home rental. It has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings.

How many vacation rentals will I find in Santa Clara?

Choose from 6 Expedia vacation rentals in Santa Clara for a memorable vacation.

What’s there to see and do in Santa Clara?

While exploring the area, visit family-friendly sights like Serpentarium, or get outside and enjoy nature at Playa Blanca. Santa Clara Beach and Farallón Beach are a couple of places you'll find in the larger area.

What’s a vacation rental in Santa Clara like?

Vacation rentals are privately owned properties you can stay in for several days or longer in Santa Clara. Vacation rentals offer amenities such as patios, hot tubs, and fire pits so you'll have all the conveniences of home. If you're concerned about a sanitized environment, a vacation rental can offer a sense of safety away from public hotel elevators and busy concierge desks while still allowing you the excitement and enjoyment of travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a popular option for small groups.