Title: 10 Best Hotels in Sanctuary, Sanibel for 2025 | Expedia.ca [Vacation Rentals in Sanibel](https://expedia.ca/Sanibel-Vacation-Rentals.d9791.Travel-Guide-VacationRentals)[Flights to Sanibel](https://expedia.ca/Cheap-Flights-To-Sanibel.d9791.Travel-Guide-Flights)[Things to do in Sanibel](https://expedia.ca/Things-To-Do-In-Sanibel.d9791.Travel-Guide-Activities)[Sanctuary Car Rentals](https://expedia.ca/Car-Rentals-In-Sanctuary.d553248635976469368.Car-Rental-Guide)[Sanctuary Vacations](https://expedia.ca/Sanctuary.d553248635976469368.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Hotels in Sanctuary, Sanibel ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Sanctuary Resort [](https://www.expedia.ca/Hotel-Search?destination=Sanctuary%2C+Wulfert%2C+Florida%2C+United+States+of+America®ionId=553248635976469368&latLong=26.482284%2C-82.168264&adults=2&startDate=2025-11-01&d1=2025-11-01&endDate=2025-11-03&d2=2025-11-03&lodging=HOTEL_RESORT) Spa [](https://www.expedia.ca/Hotel-Search?destination=Sanctuary%2C+Wulfert%2C+Florida%2C+United+States+of+America®ionId=553248635976469368&latLong=26.482284%2C-82.168264&adults=2&startDate=2025-11-01&d1=2025-11-01&endDate=2025-11-03&d2=2025-11-03&amenities=SPA_ON_SITE) Ocean view [](https://www.expedia.ca/Hotel-Search?destination=Sanctuary%2C+Wulfert%2C+Florida%2C+United+States+of+America®ionId=553248635976469368&latLong=26.482284%2C-82.168264&adults=2&startDate=2025-11-01&d1=2025-11-01&endDate=2025-11-03&d2=2025-11-03&amenities=OCEAN_VIEW) Cottage [](https://www.expedia.ca/Hotel-Search?destination=Sanctuary%2C+Wulfert%2C+Florida%2C+United+States+of+America®ionId=553248635976469368&latLong=26.482284%2C-82.168264&adults=2&startDate=2025-11-01&d1=2025-11-01&endDate=2025-11-03&d2=2025-11-03&lodging=COTTAGE) Apart hotel [](https://www.expedia.ca/Hotel-Search?destination=Sanctuary%2C+Wulfert%2C+Florida%2C+United+States+of+America®ionId=553248635976469368&latLong=26.482284%2C-82.168264&adults=2&startDate=2025-11-01&d1=2025-11-01&endDate=2025-11-03&d2=2025-11-03&lodging=APART_HOTEL) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Sanctuary%2C+Wulfert%2C+Florida%2C+United+States+of+America®ionId=553248635976469368&latLong=26.482284%2C-82.168264&adults=2&startDate=2025-11-01&d1=2025-11-01&endDate=2025-11-03&d2=2025-11-03&travelerType=family_friendly) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Sanctuary%2C+Wulfert%2C+Florida%2C+United+States+of+America®ionId=553248635976469368&latLong=26.482284%2C-82.168264&adults=2&startDate=2025-11-01&d1=2025-11-01&endDate=2025-11-03&d2=2025-11-03&amenities=PETS) Condo [](https://www.expedia.ca/Hotel-Search?destination=Sanctuary%2C+Wulfert%2C+Florida%2C+United+States+of+America®ionId=553248635976469368&latLong=26.482284%2C-82.168264&adults=2&startDate=2025-11-01&d1=2025-11-01&endDate=2025-11-03&d2=2025-11-03&lodging=CONDO) Waterpark [](https://www.expedia.ca/Hotel-Search?destination=Sanctuary%2C+Wulfert%2C+Florida%2C+United+States+of+America®ionId=553248635976469368&latLong=26.482284%2C-82.168264&adults=2&startDate=2025-11-01&d1=2025-11-01&endDate=2025-11-03&d2=2025-11-03&amenities=WATER_PARK) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Sanctuary%2C+Wulfert%2C+Florida%2C+United+States+of+America®ionId=553248635976469368&latLong=26.482284%2C-82.168264&adults=2&startDate=2025-11-01&d1=2025-11-01&endDate=2025-11-03&d2=2025-11-03&lodging=APARTMENT) Villa [](https://www.expedia.ca/Hotel-Search?destination=Sanctuary%2C+Wulfert%2C+Florida%2C+United+States+of+America®ionId=553248635976469368&latLong=26.482284%2C-82.168264&adults=2&startDate=2025-11-01&d1=2025-11-01&endDate=2025-11-03&d2=2025-11-03&lodging=VILLA) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Sanctuary%2C+Wulfert%2C+Florida%2C+United+States+of+America®ionId=553248635976469368&latLong=26.482284%2C-82.168264&adults=2&startDate=2025-11-01&d1=2025-11-01&endDate=2025-11-03&d2=2025-11-03&amenities=HOT_TUB) ## Check prices for these dates Tonight [Oct 18 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635976469368&startDate=2025-10-18&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 19 - Oct 20](https://www.expedia.ca/Hotel-Search?regionId=553248635976469368&startDate=2025-10-19&endDate=2025-10-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635976469368&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=553248635976469368&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Sanctuary hotels and places to stay ![On the beach, white sand, kayaking, motor boating](https://images.trvl-media.com/lodging/1000000/10000/3100/3079/ac9a3a07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Water view](https://images.trvl-media.com/lodging/1000000/10000/3100/3079/4914d2c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, 3 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/10000/3100/3079/17d9d33f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/3100/3079/89736118.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Sanibel Harbour Resort & Spa 15.6 km from Sanctuary 8.4/10 Very good (1014) "It is a beautiful resort! It had everything, dining , pool, very relaxing. The staff and rooms were incredible." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christine CA $265 CA $331 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Fort-Myers-Hotels-Marriott-Sanibel-Harbour-Resort-Spa.h3079.Hotel-Information) ![Deluxe Studio, 1 King Bed, Marina View | View from room](https://images.trvl-media.com/lodging/17000000/16660000/16651900/16651890/bde78c89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/17000000/16660000/16651900/16651890/w1995h1500x652y0-ac9ecb97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sundeck](https://images.trvl-media.com/lodging/17000000/16660000/16651900/16651890/2c59b397.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bicycling](https://images.trvl-media.com/lodging/17000000/16660000/16651900/16651890/e693cbff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Latitude 26 Waterfront Boutique Resort - Fort Myers Beach 21.5 km from Sanctuary 8.8/10 Excellent (1008) "This place is a gem! Rooms are so cute and the beach vibe is wonderful. Staff is very friendly and so accommodating. Looking forward to staying again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sharon CA $130 CA $145 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Fort-Myers-Hotels-Latitude-26-Waterfront-Boutique-Resort-Fort-Myers-Beach.h16651890.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/1000000/210000/200700/200632/814c4388.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/210000/200700/200632/2fcdc994.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/210000/200700/200632/c9ca07cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast served, American cuisine, beach views ](https://images.trvl-media.com/lodging/1000000/210000/200700/200632/50af8801.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DiamondHead Beach Resort 22.3 km from Sanctuary 9.0/10 Wonderful (1023) "It was a very clean friendly and safe place!!We will be back!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bryan CA $194 CA $272 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Fort-Myers-Hotels-DiamondHead-Beach-Resort.h200632.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/0be36f55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/693ea816.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/a06607fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/98f0aac3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Allure Suites 27.2 km from Sanctuary 7.6/10 Good (1016) "Friendly staff appreciated having a mini kitchen. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jerry Todd CA $95 CA $106 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Fort-Myers-Hotels-Allure-Suites.h421546.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/a69cd385.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/088bfb58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/798de6a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/fe3aa003.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG 23.1 km from Sanctuary 9.4/10 Exceptional (1011) "Great spot, good staff refreshing " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roland CA $130 CA $145 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Fort-Myers-Hotels-Holiday-Inn-Express-Suites-Ft-Myers-Beach-Sanibel-Gateway.h49152700.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2630000/2625800/2625745/83cb6bb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/3000000/2630000/2625800/2625745/2c14a98f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2630000/2625800/2625745/432e75cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/3000000/2630000/2625800/2625745/e00a9bae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Fort Myers Sanibel 19.3 km from Sanctuary 8.6/10 Excellent (1009) "Nice place to stay and staff was friendly." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Monique CA $144 CA $161 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Fort-Myers-Hotels-Residence-Inn-By-Marriott-Fort-Myers-Sanibel.h2625745.Hotel-Information) ![Suite with King Bed, Beachfront, Balcony | Terrace/patio](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/b5b17142.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sundeck](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/1808ce0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/767ba460.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Beachfront, Balcony, Two Doubles](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/de245384.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lani Kai Beachfront Resort 21.8 km from Sanctuary 8.8/10 Excellent (1059) "Very nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrea CA $226 CA $284 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11200/11134/b06bf9be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/20000/11200/11134/8f32b7a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/11200/11134/w3000h1997x0y3-c76bf6b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11200/11134/4ec8c9b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway 19.9 km from Sanctuary 8.0/10 Very good (1009) "Great place to stay and breakfast was delicious " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Keishly CA $122 CA $136 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Fort-Myers-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Ft-Myers-Sanibel-Gateway.h11134.Hotel-Information) ![View from room](https://images.trvl-media.com/lodging/93000000/92430000/92421800/92421769/ead25301.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/93000000/92430000/92421800/92421769/c1a22212.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Condo, 2 Bedrooms, Patio (waterview) | Private kitchen](https://images.trvl-media.com/lodging/93000000/92430000/92421800/92421769/1f1c096d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Condo, 1 Bedroom, Patio | Living area](https://images.trvl-media.com/lodging/93000000/92430000/92421800/92421769/5e014075.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Matlacha on Shoreview 20.2 km from Sanctuary 9.6/10 Exceptional (198) "Lovely little propery for the price!" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Kirsty CA $91 CA $195 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Cape-Coral-Hotels-Matlacha-At-Shoreview.h92421769.Hotel-Information) ![Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/1000000/560000/551900/551886/8158a459.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/560000/551900/551886/e15af7d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 Queen Beds Study with Patio](https://images.trvl-media.com/lodging/1000000/560000/551900/551886/ea38270a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/560000/551900/551886/e94c2dc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway 22.9 km from Sanctuary 8.4/10 Very good (1009) "Great stay - really friendly staff" ![Germany](https://a.travel-assets.com/egds/marks/flags/de.svg) Monika CA $137 CA $153 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Fort-Myers-Beach-Hotels-Hampton-Inn-Suites-Fort-Myers-BeachSanibel-Gateway.h551886.Hotel-Information) ![Apartment, Multiple Beds, Partial Ocean View | Beach/ocean view](https://images.trvl-media.com/lodging/12000000/11760000/11753200/11753200/fb0b7d7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 Queen Bed, Partial Ocean View](https://images.trvl-media.com/lodging/12000000/11760000/11753200/11753200/96081da3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, Multiple Beds, Beach View | Living room](https://images.trvl-media.com/lodging/12000000/11760000/11753200/11753200/1081c4bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms, Partial Ocean View](https://images.trvl-media.com/lodging/12000000/11760000/11753200/11753200/ee4ac5cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Edison Beach House 21.2 km from Sanctuary 9.4/10 Exceptional (1533) "very friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steven CA $218 CA $243 total includes taxes & fees Oct 22 - Oct 23 [](https://www.expedia.ca/Fort-Myers-Hotels-Edison-Beach-House.h11753200.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/850000/848800/848740/d8bd559a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/848800/848740/24e2211e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/850000/848800/848740/030c0a00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily cooked-to-order breakfast (USD 15.95 per person)](https://images.trvl-media.com/lodging/1000000/850000/848800/848740/fc5edcf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Ft Myers 29.5 km from Sanctuary 8.6/10 Excellent (1011) "Convenient location to shopping and dining very polite staff clean and luxurious room and delicious breakfast / Buffett will be returning " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nickelle CA $160 CA $178 total includes taxes & fees Oct 24 - Oct 25 [](https://www.expedia.ca/Fort-Myers-Hotels-Hilton-Garden-Inn-Ft-Myers.h848740.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/w2247h1500x326y0-2ea06bb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, sun loungers, beach towels](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/86e902b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/2ab8abc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, sun loungers, beach towels](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/6b3a0fb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sanibel Island Beach Resort 13.1 km from Sanctuary 9.2/10 Wonderful (1351) "The location was perfect, the rooms were freshly remodeled, clean & beautiful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sybil CA $276 CA $343 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) ![Outdoor pool, open 8:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/d961205e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/4aba0d83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms, Non Smoking, River View (Balcony)](https://images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/43311ff7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/1175676c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Cape Coral Resort At Marina Village 18.1 km from Sanctuary 9.2/10 Wonderful (1012) "Very clean room staff is amazing" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MARY CA $201 CA $277 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Fort-Myers-Hotels-The-Westin-Cape-Coral-Resort-At-Marina-Village.h2721880.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292854/13e65390.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292854/551a1a6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292854/b3765e55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292854/407fdb8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Candlewood Suites Fort Myers Sanibel Gateway by IHG 25.4 km from Sanctuary 7.4/10 Good (1005) "It was a great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donald CA $100 CA $111 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Fort-Myers-Hotels-Candlewood-Suites-Fort-Myers-Sanibel-Gateway.h2292854.Hotel-Information) ![Outdoor pool, open 7:30 AM to 9:30 PM, free cabanas, sun loungers](https://images.trvl-media.com/lodging/6000000/5110000/5107300/5107225/08406205.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/6000000/5110000/5107300/5107225/91630e70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/6000000/5110000/5107300/5107225/05f74623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Floating Coconut Cottage Houseboat](https://images.trvl-media.com/lodging/6000000/5110000/5107300/5107225/0badd225.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Latitude 26 Waterfront Resort & Marina 22 km from Sanctuary 8.6/10 Excellent (888) "Really enjoyed our stay! Made use of kayaks and felt comfortable and safe. Id def stay again! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) erica CA $146 CA $163 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/Fort-Myers-Hotels-Tip-Top-Isles-Waterfront-Resort-Marina.h5107225.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/50000/40800/40711/6c1090cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/50000/40800/40711/925dd3c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/50000/40800/40711/09cc3103.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/50000/40800/40711/0f55ab5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sanibel Inn 13.8 km from Sanctuary 9.0/10 Wonderful (1010) "The reception was welcoming and the room we stayed in was excellent." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steven CA $371 CA $495 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Fort-Myers-Hotels-Sanibel-Inn.h40711.Hotel-Information) ![2 outdoor pools](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/w2800h1779x0y3-dbc2bfa3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Offshore King Suite(Family Friendly, Not Pet Friendly) | Living area](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/faeeca91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/2db9fe7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Offshore King, 1 Bedroom Studio (Family friendly, Not Pet Friendly)](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/348f4fe8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lighthouse Resort Inn & Suites 21.5 km from Sanctuary 8.6/10 Excellent (1502) "It was close to everything and I love their 2 bedroom suite options along with the Tiki Bar" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tricia CA $140 CA $184 total includes taxes & fees Oct 22 - Oct 23 [](https://www.expedia.ca/Fort-Myers-Hotels-The-Lighthouse-Resort-Inn-Suites.h800715.Hotel-Information) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/26900/26860/ab39b98c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/26900/26860/c3c27af0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/26900/26860/3133721f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/30000/26900/26860/42ce38d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Cape Coral-Fort Myers Area by IHG 23.9 km from Sanctuary 9.2/10 Wonderful (1016) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ubaldo CA $158 CA $177 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Fort-Myers-Hotels-Holiday-Inn-Express-Cape-Coral-Fort-Myers-Area.h26860.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2670000/2665100/2665085/fc463bf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/3000000/2670000/2665100/2665085/a62366ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fishing](https://images.trvl-media.com/lodging/3000000/2670000/2665100/2665085/6e3a1f40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2670000/2665100/2665085/e46c7f87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Matanzas Inn Bayside Resort and Marina 21.6 km from Sanctuary 9.2/10 Wonderful (1016) "Great place! Great location!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela CA $170 CA $225 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Fort-Myers-Hotels-Matanzas-Inn-Bayside-Resort-And-Marina.h2665085.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-01&endDate=2025-11-02®ionId=553248635976469368&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanctuary-Sanibel-Hotels.0-n553248635976469368-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanctuary-Sanibel-Hotels.0-n553248635976469368-0.Travel-Guide-Filter-Hotels) ## Where to stay in Sanctuary Find the best Sanctuary areas and neighborhoods for the activities you enjoy most. - Beachview Country Club Estates - Shell Harbor - The Dunes - Ybel - Murex Lakes ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496031-periwinkle-way.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496033-southwest-coast-florida.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496099-periwinkle-way.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496100-periwinkle-way.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496067-periwinkle-way.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976658737) ![Beachview Country Club Estates map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:_xi%60DnhzsN%7DF%7BKm%40qJo%60%40WcFgQsIGkFm%5BlPuInCdJrU%3Fh%40cBhAh%40vCwAve%40%7CjAuVF&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=01bhKNjFz-Z_Q0nxmzzaWzGMm0I=) ### Beachview Country Club Estates If you're spending some time in Beachview Country Club Estates, Periwinkle Way and Sanibel Island Golf Club are top sights worth seeing. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976658737) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976472731) ![Shell Harbor map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:ank%60DjcvsNaa%40c%40wAuGuDr%40yQeEJ%7DG%7CBsSnIf%40hAm%40nBtLx_%40m%40pGbZUvC&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=dyLU-1Cyb2oZ37lPkaJou-mrmt0=) ### Shell Harbor Though Shell Harbor might not have many top sights, you can venture to the surrounding area to see attractions like Bailey's Beach and Sanibel Sea School. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976472731) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976473424) ![The Dunes map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:gvl%60DjqysN%5Da%40GoTiDmA%5DaKsAO_%40%60%40FnJUXoQGiJlEm%40%3F%7DEyCuX%3FWYNcW%5Ck%40jTOdAc%40%7ED_d%40rHkH%7CEqJ%7C%40q%40%7CWtE%5Cb%40%5DrAcHX%5Dj%40FbS%5Ch%40zHF%5C%60%40fEbV%60CVd%40j%40FvQ%3FzD%5Db%40kB%3F%5D%60%40%3FvTWX_EF&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=QNDycSiBNVVgdJgH6IlVnwej89o=) ### The Dunes When in The Dunes, you can plan a visit to Dunes Golf and Tennis Club and Bailey's Beach, some noteworthy sights in the nearby area. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976473424) ![](https://mediaim.expedia.com/destination/1/a6c0ed9b6d24d6c6ad71ca0a3d8d9a0a.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635975848029) ![Ybel map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:u_h%60Df%7B%7CsNcFmNz%40cJ%7EJ%7DArBnM%7C%40pMiKL&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=dWkoqOkAgwyc3m6DOLdjH2IEnRA=) ### Ybel While Ybel might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Sanibel Island Southern Beach and Periwinkle Way. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635975848029) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976468770) ![Murex Lakes map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:k_j%60Dr%7CbtNe%40oo%40%60%5D_A%5Cd%5EdIPf%40e%40Tr%40SfA%5E%60%40iAz%40i%40xA%7BAUmCrIk%5EJ&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=ydvPcTDzMQ3Z-5qFnI5mamLjTZY=) ### Murex Lakes If you're looking for some top things to see and do in Murex Lakes and surrounding area, you can visit Sanibel Island Southern Beach and Bailey - Matthews Shell Museum. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976468770) ## Top Sanctuary Hotel Reviews ## Frequently asked questions ### What is Sanctuary like? > Travelers are sure to enjoy a stay in Wulfert's Sanctuary neighborhood. Consider a visit to J. N. Ding Darling National Wildlife Refuge as part of your Sanctuary travel plans. ### How many hotels are there in the Sanctuary area? > With 13 Expedia hotels and other accommodations in Sanctuary to choose from, this is a good starting point for exploring the greater Wulfert area. ### If I need to cancel my hotel reservation in Sanctuary, will I receive a refund? > Yes! You'll find that most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to review top deals in Sanctuary. ### What is there to do around this Wulfert neighborhood? > J. N. Ding Darling National Wildlife Refuge is an attraction you might want to check out while you're in Sanctuary. Castaways Marina and Blind Pass Beach are also worth a visit when you're out sightseeing in Wulfert. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [Hotels near Alison Hagerup Beach Park](https://www.expedia.ca/Alison-Hagerup-Beach-Park-Hotels.0-l6182809-0.Travel-Guide-Filter-Hotels) - [Hotels near Bailey - Matthews Shell Museum](https://www.expedia.ca/Bailey-Matthews-Shell-Museum-Hotels.0-l6123901-0.Travel-Guide-Filter-Hotels) - [Hotels near Bowman's Beach](https://www.expedia.ca/Bowmans-Beach-Hotels.0-l6296151-0.Travel-Guide-Filter-Hotels) - [Bright Water Hotels](https://www.expedia.ca/Bright-Water-Sanibel-Hotels.0-n553248635976473851-0.Travel-Guide-Filter-Hotels) - [Aparthotels in Captiva](https://www.expedia.ca/Captiva-Apart-Hotels.d86452-aaApartHotels.Travel-Guide-Accommodation) - [Apartments in Captiva](https://www.expedia.ca/Captiva-Apartments.d86452-aaApartments.Travel-Guide-Accommodation) - [Hotels near Captiva Beach](https://www.expedia.ca/Captiva-Beach-Hotels.0-l6296288-0.Travel-Guide-Filter-Hotels) - 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