Title: Book the Best BUSINESS Hotels in Downtown San Diego in 2025 | Expedia.ca [Downtown San Diego Travel Guide](https://expedia.ca/San-Diego-Downtown-San-Diego.dx800123)[Vacation Rentals in San Diego](https://expedia.ca/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)[Flights to San Diego](https://expedia.ca/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.ca/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Downtown San Diego Car Rentals](https://expedia.ca/Car-Rentals-In-Downtown-San-Diego.d800123.Car-Rental-Guide)[Downtown San Diego Vacations](https://expedia.ca/Downtown-San-Diego.d800123.Destination-Travel-Guides) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/480000/480742-Maritime-Museum-Of-San-Diego.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Downtown San Diego, CA from CA $180 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Downtown San Diego Business Hotels Tonight [Oct 9 - Oct 10](https://www.expedia.ca/Hotel-Search?regionId=800123&startDate=2025-10-09&endDate=2025-10-10&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 10 - Oct 11](https://www.expedia.ca/Hotel-Search?regionId=800123&startDate=2025-10-10&endDate=2025-10-11&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=800123&startDate=2025-10-10&endDate=2025-10-12&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=800123&startDate=2025-10-17&endDate=2025-10-19&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Downtown San Diego Business Hotels ![Exterior](https://images.trvl-media.com/lodging/3000000/2920000/2918200/2918129/a0a6825c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2920000/2918200/2918129/f3168007.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2920000/2918200/2918129/49bcb235.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2920000/2918200/2918129/e3befa7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter Downtown San Diego 9.0/10 Wonderful (1156) "Clean room ,friendly staff, great location " CA $201 CA $233 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/San-Diego-Hotels-Residence-Inn-By-Marriott-San-Diego-DowntownGaslamp-Quarter.h2918129.Hotel-Information) ![Pillowtop beds, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/50000/40700/40681/a459623d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/50000/40700/40681/59e49d5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/50000/40700/40681/cea2c55c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/40700/40681/a0831a86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express San Diego Downtown by IHG Downtown San Diego 8.4/10 Very good (1478) "It was a very clean and safe place to stay" CA $166 CA $193 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/San-Diego-Hotels-Holiday-Inn-Express-San-Diego-Downtown.h40681.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/9fc82331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Californian cuisine, ocean views ](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/06f19e3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/2df2def5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, lobby lounge](https://images.trvl-media.com/lodging/2000000/1880000/1871700/1871645/ed2e1ba0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton San Diego Bayfront Downtown San Diego 8.6/10 Excellent (1775) "My stay here is excellent and the staff is amazing. " CA $268 CA $379 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/San-Diego-Hotels-Hilton-San-Diego-Bayfront.h1871645.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/84efd019.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/36f8ccfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/w3840h2557x0y3-2d2de3f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/180000/170400/170338/w3837h2560x3y0-07d390b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The DEXTRO Little Italy, BW Premier Collection Downtown San Diego 8.8/10 Excellent (522) "Great place to stay! " CA $155 CA $180 total includes taxes & fees Oct 15 - Oct 16 [](https://www.expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) ![Outdoor pool, open 7:00 AM to 10:00 PM, free cabanas, sun loungers](https://images.trvl-media.com/lodging/14000000/13340000/13339900/13339817/308d14a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/14000000/13340000/13339900/13339817/dc05fea3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/14000000/13340000/13339900/13339817/a15a7e64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Harbour View | View from room](https://images.trvl-media.com/lodging/14000000/13340000/13339900/13339817/15c37db5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn San Diego Downtown/Bayside Downtown San Diego 8.6/10 Excellent (1168) "We like our stay " CA $203 CA $235 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/San-Diego-Hotels-Hilton-Garden-Inn-San-Diego-DowntownBayside.h13339817.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/920000/914400/914373/236157bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/920000/914400/914373/w395h595x4y3-183171c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/920000/914400/914373/dc860349.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/920000/914400/914373/8114cbc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Pensione Hotel Downtown San Diego 8.6/10 Excellent (1874) "Great place to stay they are right in the middle of everything " CA $187 CA $213 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/San-Diego-Hotels-La-Pensione-Hotel.h914373.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/13000000/12070000/12068000/12067966/ff498cc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed with Sofa bed, Non Smoking, Bay View (Corner)](https://images.trvl-media.com/lodging/13000000/12070000/12068000/12067966/0efa27d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/13000000/12070000/12068000/12067966/f032ed38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed with Sofa bed, Non Smoking, Bay View (Corner)](https://images.trvl-media.com/lodging/13000000/12070000/12068000/12067966/cba705bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Springhill Suites San Diego Downtown/Bayfront Downtown San Diego 9.2/10 Wonderful (1005) "We had a great time, will stay again!" CA $262 CA $305 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/San-Diego-Hotels-Springhill-Suites-San-Diego-DowntownBayfront.h12067966.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/ba6cea84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/75ec9582.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Suite, 2 Double Beds, Roll-in Shower, City View](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/c0dfd2f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/589f8e80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Sofia Hotel Downtown San Diego 8.4/10 Very good (1607) "I loved the stay here, highly recommended " CA $143 CA $199 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/San-Diego-Hotels-The-Sofia-Hotel.h1573807.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/7f3bc7ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City view](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/88f9cd22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/5142b853.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham San Diego Bayside Downtown San Diego 8.4/10 Very good (5988) "Great stay near the airport." CA $212 CA $287 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21200/21135/5c5f8e88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 King Bed, Balcony, Bay View](https://images.trvl-media.com/lodging/1000000/30000/21200/21135/c18834b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/21200/21135/dd9a437a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/30000/21200/21135/5f4328a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin San Diego Gaslamp Quarter Downtown San Diego 8.8/10 Excellent (1010) "Clean room, friendly staff" CA $262 CA $345 total includes taxes & fees Oct 31 - Nov 1 [](https://www.expedia.ca/San-Diego-Hotels-The-Westin-San-Diego-Gaslamp-Quarter.h21135.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-24&endDate=2025-10-25®ionId=800123&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Price trends for hotels in Downtown San Diego | Less expensive | More expensive | This month | Next month | | --- | --- | --- | --- | | December | June | CA $260 | CA $256 | | Month | Price | | --- | --- | | January | CA $297 | | February | CA $343 | | March | CA $362 | | April | CA $405 | | May | CA $415 | | June | CA $498 | | July | CA $479 | | August | CA $440 | | September | CA $450 | | October | CA $260 | | November | CA $256 | | December | CA $223 | Price trend information excludes taxes and fees and is based on base rates for a nightly stay for 2 adults found in the last 7 days on our site and averaged for commonly viewed hotels in Downtown San Diego. Select dates and complete search for nightly totals inclusive of taxes and fees. ## Top Downtown San Diego Hotel Reviews ![The DEXTRO Little Italy, BW Premier Collection](//images.trvl-media.com/lodging/1000000/180000/170400/170338/84efd019_y.jpg) ### The DEXTRO Little Italy, BW Premier Collection 10/10 Excellent "Very Convenient being a few blocks away from little italy and then the metro station was right there too!" [](https://expedia.ca/San-Diego-Hotels-Four-Points-By-Sheraton-San-Diego-Downtown-Little-Italy.h170338.Hotel-Information) ![Embassy Suites by Hilton San Diego Bay Downtown](//images.trvl-media.com/lodging/1000000/10000/5400/5328/cfe599b5_y.jpg) ### Embassy Suites by Hilton San Diego Bay Downtown 10/10 Excellent "Amazing stay!! The staff and location were incredible. As soon as we arrived, the staff made us feel welcomed. Morning breakfast had great options. " [](https://expedia.ca/San-Diego-Hotels-Embassy-Suites-By-Hilton-San-Diego-Bay-Downtown.h5328.Hotel-Information) ![Hard Rock Hotel San Diego](//images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Very clean, easy to move a lot things to do and Tourist Really love it" [](https://expedia.ca/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![The Sofia Hotel](//images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/ba6cea84_y.jpg) ### The Sofia Hotel 10/10 Excellent "Great location for the gaslamp" [](https://expedia.ca/San-Diego-Hotels-The-Sofia-Hotel.h1573807.Hotel-Information) ![Wyndham San Diego Bayside](//images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "Loved the location & ease of access to the city." [](https://expedia.ca/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Margaritaville Hotel San Diego Gaslamp Quarter](//images.trvl-media.com/lodging/2000000/1120000/1117700/1117693/0db99a00_y.jpg) ### Margaritaville Hotel San Diego Gaslamp Quarter 10/10 Excellent "Perfect for a small conference" [](https://expedia.ca/San-Diego-Hotels-Solamar-San-Diego.h1117693.Hotel-Information) ![Manchester Grand Hyatt San Diego](//images.trvl-media.com/lodging/1000000/20000/12100/12073/w3840h2092x0y3-447c77a4_y.jpg) ### Manchester Grand Hyatt San Diego 10/10 Excellent "The staff was very helpful and accommodating whenever I needed something they were able to help me right away and had a quick response if I needed to have anything delivered to the room or any other questions I had" [](https://expedia.ca/San-Diego-Hotels-Manchester-Grand-Hyatt-San-Diego.h12073.Hotel-Information) ![Pendry San Diego](//images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/05d0e601_y.jpg) ### Pendry San Diego 10/10 Excellent "Staff was so friendly and welcoming. " [](https://expedia.ca/San-Diego-Hotels-Pendry-San-Diego.h16298963.Hotel-Information) ![Marriott Marquis San Diego Marina](//images.trvl-media.com/lodging/1000000/30000/24400/24394/9078a9ee_y.jpg) ### Marriott Marquis San Diego Marina 10/10 Excellent "Clean, amazing staff, wheel chair accessible " [](https://expedia.ca/San-Diego-Hotels-Marriott-Marquis-San-Diego-Marina.h24394.Hotel-Information) ## Frequently asked questions ### Why book your business-friendly hotel in Downtown San Diego with Expedia? > Expedia is here to help you find a fantastic business-friendly hotel when work takes you out of town. From free parking and WiFi to on-site restaurants and cafés, our stays come with all you'll need to settle that big contract. ### How can I find cheap business-friendly hotels in Downtown San Diego? > Expedia can help you easily find cheap business-friendly hotels in Downtown San Diego. Head to our "traveller experience" filter and click on "business friendly." This will show you stays with amenities designed to help you work and rest comfortably, like free WiFi and included breakfast. 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