Title: Book the Best BUSINESS Hotels in San Luis Obispo Wine Country in 2026 | Expedia.ca [San Luis Obispo Wine Country Travel Guide](https://expedia.ca/San-Luis-Obispo-Wine-Country.dx553248621593965865)[Hotels in San Luis Obispo Wine Country](https://expedia.ca/San-Luis-Obispo-Wine-Country-Hotels.d553248621593965865.Travel-Guide-Hotels)[Vacation Rentals in San Luis Obispo Wine Country](https://expedia.ca/San-Luis-Obispo-Wine-Country-Vacation-Rentals.d553248621593965865.Travel-Guide-VacationRentals)[Flights to San Luis Obispo Wine Country](https://expedia.ca/Cheap-Flights-To-San-Luis-Obispo-Wine-Country.d553248621593965865.Travel-Guide-Flights)[San Luis Obispo Wine Country Car Rentals](https://expedia.ca/Car-Rentals-In-San-Luis-Obispo-Wine-Country.d553248621593965865.Car-Rental-Guide)[San Luis Obispo Wine Country Vacation Packages](https://expedia.ca/San-Luis-Obispo-Wine-Country.d553248621593965865.Destination-Travel-Guides) ![#Hiking along the coast of Avila Beach in California. While hiking in this area, BEWARE, because on your left from this spot, is the Nude Beach. Yup, it's the only nude beach that I know of that still exist in California. P.s. It was an accidental find for us, and no, we didn't go. #Waterlust #WeekendGetaway](https://images.trvl-media.com/place/11911/da9298a6-d014-4db2-a780-5eb15f4e4aae.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Anthony Hilario ![](https://images.trvl-media.com/place/11911/da9298a6-d014-4db2-a780-5eb15f4e4aae.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on San Luis Obispo Wine Country Business Hotels Tonight [Jan 29 - Jan 30](https://www.expedia.ca/Hotel-Search?regionId=553248621593965865&startDate=2026-01-29&endDate=2026-01-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Jan 30 - Jan 31](https://www.expedia.ca/Hotel-Search?regionId=553248621593965865&startDate=2026-01-30&endDate=2026-01-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=553248621593965865&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=553248621593965865&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for San Luis Obispo Wine Country business-friendly hotels ![Outdoor pool, pool umbrellas](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/1ea42b7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, individually decorated](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/45433961.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, individually decorated](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/63206dec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/eaa8a221.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Madonna Inn [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Madonna-Inn.h1190976.Hotel-Information) San Luis Obispo 9.2/10 Wonderful (1,367 reviews) "Nice room, clean, friendly staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roxana CA $186 CA $258 total includes taxes & fees Feb 4 - Feb 5 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Madonna-Inn.h1190976.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/1000000/40000/39500/39435/f5438f41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 9:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/40000/39500/39435/880cde75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/39500/39435/cd19526e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/40000/39500/39435/462ce0c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apple Farm [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Apple-Farm.h39435.Hotel-Information) San Luis Obispo 9.0/10 Wonderful (1,597 reviews) "Amazing stay - loved the room and the property! Absolutely loved it and can’t wait to go back" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jinna [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Apple-Farm.h39435.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42000/41941/83cec734.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/50000/42000/41941/a0f0bdf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42000/41941/27e8ce9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42000/41941/e7d3c4b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vagabond Inn San Luis Obispo [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Vagabond-Inn-San-Luis-Obispo.h41941.Hotel-Information) San Luis Obispo 8.4/10 Very good (1,212 reviews) "Great room for the price" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kishan CA $77 CA $103 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Vagabond-Inn-San-Luis-Obispo.h41941.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/15500/15406/be1d8b89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Suite, 1 King Bed, Accessible (Mobility & Hearing - Roll-in Shower)](https://images.trvl-media.com/lodging/1000000/20000/15500/15406/a8050678.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15500/15406/b27f9120.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/15500/15406/a8c81bdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites by Hilton San Luis Obispo [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Embassy-Suites-By-Hilton-San-Luis-Obispo.h15406.Hotel-Information) San Luis Obispo 8.8/10 Excellent (1,316 reviews) "Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Areli CA $131 CA $149 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Embassy-Suites-By-Hilton-San-Luis-Obispo.h15406.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/28000000/27200000/27194600/27194534/99fa5dc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27200000/27194600/27194534/95fd9e4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27200000/27194600/27194534/d050f4c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served, American cuisine](https://images.trvl-media.com/lodging/28000000/27200000/27194600/27194534/d0e886ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown [](https://www.expedia.ca/San-Luis-Obispo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Luis-Obispo-Downtown.h27194534.Hotel-Information) San Luis Obispo 9.0/10 Wonderful (1,861 reviews) "Lovely property, nice clean room and great breakfast! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robin CA $177 CA $201 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-San-Luis-Obispo-Downtown.h27194534.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/112000000/111660000/111653900/111653811/cb2f400e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/112000000/111660000/111653900/111653811/d97ba677.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/112000000/111660000/111653900/111653811/ef7b31d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/112000000/111660000/111653900/111653811/c9526654.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott San Luis Obispo [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Residence-Inn-By-Marriott-San-Luis-Obispo.h111653811.Hotel-Information) San Luis Obispo 9.2/10 Wonderful (104 reviews) "Clean Room, Helpful Staff, Breakfast, Evening Bar" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lesley CA $206 CA $234 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Residence-Inn-By-Marriott-San-Luis-Obispo.h111653811.Hotel-Information) ![View from room](https://images.trvl-media.com/lodging/2000000/1380000/1379200/1379138/00638b10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/2000000/1380000/1379200/1379138/b29cd20f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor banquet area](https://images.trvl-media.com/lodging/2000000/1380000/1379200/1379138/8a33ff76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch flat-screen TV with digital channels, TV, pay movies](https://images.trvl-media.com/lodging/2000000/1380000/1379200/1379138/04635922.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Avila Lighthouse Suites [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Avila-Lighthouse-Suites.h1379138.Hotel-Information) Avila Beach 9.4/10 Exceptional (1,000 reviews) "Clean room, quietness, great location right on front of the ocean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sang Wook CA $203 CA $306 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Avila-Lighthouse-Suites.h1379138.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4860000/4857100/4857071/893b69cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4860000/4857100/4857071/24c94233.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Accessible, Non Smoking (Roll-In Shower) | Living area](https://images.trvl-media.com/lodging/5000000/4860000/4857100/4857071/8845c585.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/5000000/4860000/4857100/4857071/e223e26f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites San Luis Obispo [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hampton-Inn-And-Suites-San-Luis-Obispo.h4857071.Hotel-Information) San Luis Obispo 8.8/10 Excellent (1,000 reviews) "Great staff, great room, comfortable bed, delicious breakfast!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Linnea CA $141 CA $160 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hampton-Inn-And-Suites-San-Luis-Obispo.h4857071.Hotel-Information) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/3900/3864/8d25ff25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/3900/3864/c518ad88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, a heated pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/3900/3864/da856618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/3900/3864/c3f0f2f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Royal Oak Hotel [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Best-Western-Plus-Royal-Oak-Hotel.h3864.Hotel-Information) San Luis Obispo 8.6/10 Excellent (1,000 reviews) "Staff was nice. Amenities was good." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christy CA $151 CA $171 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Best-Western-Plus-Royal-Oak-Hotel.h3864.Hotel-Information) ![Fireplace](https://images.trvl-media.com/lodging/2000000/1680000/1674700/1674664/784d3c40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1680000/1674700/1674664/8cea3a2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1680000/1674700/1674664/43b3fdb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach](https://images.trvl-media.com/lodging/2000000/1680000/1674700/1674664/c1f297fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott San Luis Obispo [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Courtyard-By-Marriott-San-Luis-Obispo.h1674664.Hotel-Information) San Luis Obispo 8.6/10 Excellent (1,001 reviews) "Room was spacious " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christy CA $160 CA $182 total includes taxes & fees Feb 17 - Feb 18 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Courtyard-By-Marriott-San-Luis-Obispo.h1674664.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-12&endDate=2026-02-13®ionId=553248621593965865&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top San Luis Obispo Wine Country Hotel Reviews ![Quality Suites Downtown San Luis Obispo](https://images.trvl-media.com/lodging/1000000/10000/3200/3138/9ac45291_y.jpg) ### Quality Suites Downtown San Luis Obispo 10/10 Excellent "Large rooms good breakfast. The place has a resort vibe. The beds were very comfortable with the best feeling sheets I was surprised that the rooms do not have individual thermostats. " [](https://expedia.ca/San-Luis-Obispo-Hotels-Quality-Suites-Downtown-San-Luis-Obispo.h3138.Hotel-Information) ![Embassy Suites by Hilton San Luis Obispo](https://images.trvl-media.com/lodging/1000000/20000/15500/15406/48c2929b_y.jpg) ### Embassy Suites by Hilton San Luis Obispo 10/10 Excellent "Excellent service, we really enjoyed our stay." [](https://expedia.ca/San-Luis-Obispo-Hotels-Embassy-Suites-By-Hilton-San-Luis-Obispo.h15406.Hotel-Information) ![Vagabond Inn San Luis Obispo](https://images.trvl-media.com/lodging/1000000/50000/42000/41941/488fecb6_y.jpg) ### Vagabond Inn San Luis Obispo 10/10 Excellent "Friendly staff, easy check in, food and shops close by, very clean and spacious room. I stay in the area often and will definitely stay their again." [](https://expedia.ca/San-Luis-Obispo-Hotels-Vagabond-Inn-San-Luis-Obispo.h41941.Hotel-Information) ![Avenue Inn Downtown San Luis Obispo](https://images.trvl-media.com/lodging/1000000/70000/67500/67485/ec6a1c5f_y.jpg) ### Avenue Inn Downtown San Luis Obispo 10/10 Excellent "Very helpful staff" [](https://expedia.ca/San-Luis-Obispo-Hotels-Avenue-Inn-Downtown-San-Luis-Obispo.h67485.Hotel-Information) ![Spyglass Inn](https://images.trvl-media.com/lodging/1000000/50000/41300/41235/44c3350f_y.jpg) ### Spyglass Inn 10/10 Excellent "Great room" [](https://expedia.ca/San-Luis-Obispo-Hotels-Spyglass-Inn.h41235.Hotel-Information) ![La Cuesta Inn, BW Signature Collection](https://images.trvl-media.com/lodging/1000000/20000/14400/14372/f5b74a44_y.jpg) ### La Cuesta Inn, BW Signature Collection 10/10 Excellent "Check in staff was so friendly and helpful; the room is beautiful, clean, and the heat/ac works very efficiently and quietly. " [](https://expedia.ca/San-Luis-Obispo-Hotels-La-Cuesta-Inn.h14372.Hotel-Information) ![Apple Farm](https://images.trvl-media.com/lodging/1000000/40000/39500/39435/f5438f41_y.jpg) ### Apple Farm 10/10 Excellent "Yes, the room was spotless and comfortable. " [](https://expedia.ca/San-Luis-Obispo-Hotels-Apple-Farm.h39435.Hotel-Information) ![Madonna Inn](https://images.trvl-media.com/lodging/2000000/1200000/1191000/1190976/1ea42b7b_y.jpg) ### Madonna Inn 10/10 Excellent "It was an amazing!! Had my daughter's 16th birthday here and it was perfect. We are locals and frequent the Madonna Inn often. It's always an experience that you never forget." [](https://expedia.ca/San-Luis-Obispo-Hotels-Madonna-Inn.h1190976.Hotel-Information) ![Avila Village Inn](https://images.trvl-media.com/lodging/2000000/1180000/1178000/1177942/d33bd7d9_y.jpg) ### Avila Village Inn 10/10 Excellent "Everything was beautiful, thank you so much!" [](https://expedia.ca/San-Luis-Obispo-Hotels-Avila-Village-Inn.h1177942.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in San Luis Obispo Wine Country cost? ### What are the best business-friendly hotels in San Luis Obispo Wine Country? ### How many business-friendly hotels are there in San Luis Obispo Wine Country? ### What are the top business-friendly motels in San Luis Obispo Wine Country? ### Are there any family-friendly hotels in San Luis Obispo Wine Country that are also business friendly? ### Are there any 5-star business-friendly hotels in San Luis Obispo Wine Country? ### Why book your business-friendly hotel in San Luis Obispo Wine Country with Expedia? ### How can I find cheap business-friendly hotels in San Luis Obispo Wine Country? ### What is there to do in San Luis Obispo Wine Country near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [Hotels near Cerro San Luis Obispo ](https://www.expedia.ca/Cerro-San-Luis-Obispo-Hotels.0-l553248621532640001-0.Travel-Guide-Filter-Hotels) - 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[Shopping Hotels in Santa Barbara ](https://www.expedia.ca/Santa-Barbara-Hotels-Shopping-Hotel.0-0-d602277-tShoppingHotel.Travel-Guide-Filter-Hotels) - [Ski Hotels in Santa Barbara ](https://www.expedia.ca/Santa-Barbara-Hotels-Ski-Hotel.0-0-d602277-tSkiHotel.Travel-Guide-Filter-Hotels) - [Flights to San Luis Obispo County Regional ](https://www.expedia.ca/Cheap-Flights-To-San-Luis-Obispo-County-Regional.d6031729.Travel-Guide-Flights) - [Flights to San Luis Obispo ](https://www.expedia.ca/Cheap-Flights-To-San-Luis-Obispo.d6046822.Travel-Guide-Flights) - [Flights from San Luis Obispo County Regional ](https://www.expedia.ca/lp/airports/sbp/flights-from-san-luis-obispo-county-regional-airport) - [Flights from Bishop (BIH) to San Luis Obispo (SBP) ](https://www.expedia.ca/lp/flights/bih/sbp/bishop-to-san-luis-obispo) - [Flights from Bellingham (BLI) to San Luis Obispo (SBP) ](https://www.expedia.ca/lp/flights/bli/sbp/bellingham-to-san-luis-obispo) - [Flights from Buffalo (BUF) to San Luis Obispo (SBP) ](https://www.expedia.ca/lp/flights/buf/sbp/buffalo-to-san-luis-obispo) - 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