Antofagasta Region Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to CA $1,096 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Top vacation destinations in Antofagasta Region

San Pedro de Atacama as well as a small group of people
FlightsFlightsHotelsHotels

San Pedro de Atacama

San Pedro de Atacama

Top Antofagasta Region Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Hotel Modular Express Calama

Hotel Modular Express Calama

2.5 out of 5
Price was CA $1,933, price is now CA $1,733 per person
CA $1,733
per person
Oct 17 - Oct 23
found 21 hours ago
Roundtrip non-stop flight included
Kingston (KIN) to Calama (CJC)
7.8/10 Good! (57 reviews)
Really nice overall but a bit noisy outside

Reviewed on Mar. 8, 2025

Tierra Atacama

Tierra Atacama

4.5 out of 5
Price was CA $11,616, price is now CA $8,837 per person
CA $8,837
per person
Nov 16 - Nov 22
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Calama (CJC)
9.8/10 Exceptional! (44 reviews)
Staff and our guide Cyna was excellent. Hotel manager Maria made sure our stay was comfortable and enjoyable. Our room was cleaned and stocked without any complaints. All in all they were great.

Reviewed on Aug. 18, 2025

UNAI Atacama Luxury Tents

UNAI Atacama Luxury Tents

3.5 out of 5
Price was CA $8,188, price is now CA $6,844 per person
CA $6,844
per person
Nov 16 - Nov 22
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Calama (CJC)
No reviews
Hotel Agua del Desierto

Hotel Agua del Desierto

3.5 out of 5
Price was CA $2,332, price is now CA $1,960 per person
CA $1,960
per person
Oct 17 - Oct 23
found 21 hours ago
Roundtrip non-stop flight included
Kingston (KIN) to Calama (CJC)
8.8/10 Excellent! (81 reviews)
convenient location with very helpful staff

Reviewed on Dec. 8, 2024

Lodge Quelana

Lodge Quelana

3 out of 5
Price was CA $2,828, price is now CA $2,473 per person
CA $2,473
per person
Oct 17 - Oct 23
found 21 hours ago
Roundtrip non-stop flight included
Kingston (KIN) to Calama (CJC)
10/10 Exceptional! (108 reviews)
This is a lovely retreat. Each room is an individual cabana. The decor in the room was beautiful, and the landscaping of the grounds is wonderful. The staff was extremely gracious. I used this as a base to explore the area for 3 days and it was perfect. I had a rental car and explored on my own without booking any tours. It was easy and safe. A perfect trip. I will do it again soon.

Reviewed on Aug. 6, 2025

Antofagasta Region Hotel Deals

Diego de Almagro San Pedro de Atacama

Diego de Almagro San Pedro de Atacama

3 out of 5
Toconao 460, San Pedro de Atacama, Antofagasta
Fully refundableReserve now, pay when you stay
The price is CA $151 per night from Sep 5 to Sep 6
CA $151
CA $151 total
Sep 5 - Sep 6
Diego de Almagro San Pedro de Atacama
Park Hotel Calama

Park Hotel Calama

3.5 out of 5
Alcalde Jose Lira 1392, Calama, Antofagasta
Fully refundableReserve now, pay when you stay
The price is CA $75 per night from Sep 4 to Sep 5
CA $75
CA $75 total
Sep 4 - Sep 5
Park Hotel Calama
Hotel Cumbres San Pedro de Atacama

Hotel Cumbres San Pedro de Atacama

4 out of 5
Avenida Las Chilcas S/N, Lote 10 Parcela 2, San Pedro de Atacama, Antofagasta
The price is CA $334 per night from Oct 1 to Oct 2
CA $334
CA $334 total
Oct 1 - Oct 2
Hotel Cumbres San Pedro de Atacama
See all 291 properties in Antofagasta Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Frequently asked questions

How much does an Antofagasta Region vacation package cost?
From as low as CA $1,733. Yes, you read that right. Our Antofagasta Region packages are the best way to stretch your budget. Combine your hotels, flights and car rentals and discover this lively destination.
How do I get a cheap travel package to Antofagasta Region?
Our Antofagasta Region vacation packages promise plenty of savings for the savvy traveler. For the best deals, simply bundle your hotel, flights and activities into an affordable package. But impressive bargains are only the start of your next unforgettable adventure. Book with Expedia and you'll have more than 550 airlines and 1,000,000 properties throughout the world to pick from. Whatever your budget, there's a package that's perfect for you.
What are the top hotels in Antofagasta Region?
Have a look at ibis Antofagasta and NH Antofagasta. They're the first choice for lots of travelers to Antofagasta. If San Pedro de Atacama is on your travel itinerary, Park Hotel Calama and Noi Casa Atacama are cozy options.
How far in advance should I book my Antofagasta Region vacation?
It can be tricky to know when is the ideal time to book your trip to Antofagasta Region. But typically the earlier you book, the better the prices. Sometimes, you can reserve your flights and hotels up to a year before your departure date. If you're considering a last-minute getaway, no need to stress! There are fabulous deals featured on Expedia every single day.
What does an Expedia Antofagasta Region travel package include?
From hotels and airfares to rental cars, Expedia can help you shape an Antofagasta Region package that's perfect for you. Vacationing for a week or two? Consider a rental car, hotel and flight bundle. If you're taking a short break, a flight and hotel deal could be more your style. Activities can also be added once you've made your booking. Our vacation packages make it simple to save and plan.
What should I know before booking an Antofagasta Region travel package?
Tailor deals to suit your budget with an Expedia package. Airfares, hotels, rental cars — we're a one-stop shop for all of them. You'll save precious dollars just for bundling your bookings. Whether you're embarking on a skiing adventure or drinking cocktails on a beach, your perfect getaway is just clicks away.
Can I choose my airline with an Antofagasta Region Expedia vacation package?
Expedia has access to more than 550 airline partners worldwide, so you sure can! Simply select your preferred carrier and put together the perfect Antofagasta Region trip.
If I'm not able to travel, can I cancel my Antofagasta Region vacation package?
Whether it's your flight or hotel, you can cancel and rebook it. Locked in your Antofagasta Region vacation package in the last 24 hours? You may be able to make changes at no cost. For bookings older than that, you may be charged a fee by your hotel, airline or car rental company. For further information, visit our Customer Service Portal. We'll help you every step of the way.

Discover the most popular places to visit in Antofagasta Region

Plaza de San Pedro de Atacama

Plaza de San Pedro de Atacama

You can find out about the history of San Pedro de Atacama when you stop by Plaza de San Pedro de Atacama. You can seek out the local tours in this quaint area.

Plaza de San Pedro de Atacama
Valle de la Luna featuring desert views

Valley of the Moon

Treat your eyes to the variety of colors in a deserted valley that looks like a scene from a science fiction movie.

Valley of the Moon
Piedra del Coyote Overlook

Piedra del Coyote Overlook

Explore the great outdoors at Piedra del Coyote Overlook, a lovely green space in San Pedro de Atacama. You can seek out the local tours in this quaint area.

Piedra del Coyote Overlook

What to do in Antofagasta Region

Altiplanic Lagoons

4 Tours to Discover Atacama (3 days)

CA $343
per adult
4 Tours to Discover Atacama (3 days)
San Pedro de Atacama: 3-Day Activity Combo with 4 Tours

San Pedro de Atacama: 3-Day Activity Combo with 4 Tours

CA $330
per adult
100% of travellers recommend
San Pedro de Atacama: 3-Day Activity Combo with 4 Tours
San Pedro de Atacama: Etno-Stargazing Tour with Transfer

San Pedro de Atacama: Etno-Stargazing Tour with Transfer

CA $55
per adult
San Pedro de Atacama: Etno-Stargazing Tour with Transfer
See all activities in Antofagasta Region
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.