Title: Book the Best BUSINESS Hotels in Quad Cities in 2026 | Expedia.ca [Quad Cities Travel Guide](https://expedia.ca/Quad-Cities.dx603001)[Hotels in Quad Cities](https://expedia.ca/Quad-Cities-Hotels.d603001.Travel-Guide-Hotels)[Vacation Rentals in Quad Cities](https://expedia.ca/Quad-Cities-Vacation-Rentals.d603001.Travel-Guide-VacationRentals)[Flights to Quad Cities](https://expedia.ca/Cheap-Flights-To-Quad-Cities.d603001.Travel-Guide-Flights)[Things to do in Quad Cities](https://expedia.ca/Things-To-Do-In-Quad-Cities.d603001.Travel-Guide-Activities)[Quad Cities Car Rentals](https://expedia.ca/Car-Rentals-In-Quad-Cities.d603001.Car-Rental-Guide)[Quad Cities Vacation Packages](https://expedia.ca/Quad-Cities.d603001.Destination-Travel-Guides) ![Davenport which includes a bridge and a river or creek](https://images.trvl-media.com/place/10445/64d9566f-810c-41ab-80c2-bf561cd176b8.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Quad Cities from CA $111 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Quad Cities Business Hotels Tonight [Dec 8 - Dec 9](https://www.expedia.ca/Hotel-Search?regionId=603001&startDate=2025-12-08&endDate=2025-12-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 9 - Dec 10](https://www.expedia.ca/Hotel-Search?regionId=603001&startDate=2025-12-09&endDate=2025-12-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=603001&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=603001&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top Quad Cities Business Hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/28200/28199/w3839h2586x0y0-7ce07d45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily cooked-to-order breakfast for a fee](https://images.trvl-media.com/lodging/1000000/30000/28200/28199/d7ad7127.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed](https://images.trvl-media.com/lodging/1000000/30000/28200/28199/09fc0f96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/28200/28199/2c87e290.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Davenport Downtown Davenport 7.4/10 Good (1006) "Great downtown location. Very friendly staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Adam CA $111 CA $124 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/Davenport-Hotels-DoubleTree-By-Hilton-Davenport.h28199.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/43400/43329/bc3dbe4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor spa tub](https://images.trvl-media.com/lodging/1000000/50000/43400/43329/7a85d965.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/50000/43400/43329/6856d132.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/50000/43400/43329/8218adec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Moline on John Deere Commons Moline 9.0/10 Wonderful (1219) "Clean room , breakfast was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles CA $123 CA $139 total includes taxes & fees Dec 23 - Dec 24 [](https://www.expedia.ca/Moline-Hotels-Radisson-On-John-Deere-Commons-Moline.h43329.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/30000000/29520000/29516100/29516065/bb721367.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/30000000/29520000/29516100/29516065/be8ae851.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/30000000/29520000/29516100/29516065/2157101d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/30000000/29520000/29516100/29516065/bfc34636.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt House East Moline Quad Cities East Moline 9.2/10 Wonderful (1001) "The room was very clean and the staff were amazing. The view of the river was very relaxing as well. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dara CA $128 CA $143 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/East-Moline-Hotels-Hyatt-House-East-Moline-Quad-Cities.h29516065.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/20000000/19840000/19835500/19835449/27ed65a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/20000000/19840000/19835500/19835449/00918b58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/20000000/19840000/19835500/19835449/cda72878.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/20000000/19840000/19835500/19835449/24442645.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Element Moline Moline 9.4/10 Exceptional (650) "Amazing staff, immaculate rooms, and and great food and atmosphere. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paola CA $148 CA $170 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Moline-Hotels-Element-Moline.h19835449.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/55000000/54030000/54026000/54025963/4715d2a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/55000000/54030000/54026000/54025963/28830d0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/55000000/54030000/54026000/54025963/2e125d8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/55000000/54030000/54026000/54025963/3311940e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Davenport Quad Cities Davenport 9.4/10 Exceptional (405) "Room was clean and spacious, breakfast was delicious, and staff was kind and accommodating. Would absolutely stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Connor CA $140 CA $156 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/Quad-Cities-Hotels-Fairfield-Inn-Suites-By-Marriott-Davenport-Quad-Cities.h54025963.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1780000/1772100/1772036/47d7cf92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1780000/1772100/1772036/0a2a3e3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed with Sofa bed](https://images.trvl-media.com/lodging/2000000/1780000/1772100/1772036/d5a99adc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1780000/1772100/1772036/43d5cd7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Davenport Davenport 9.2/10 Wonderful (993) "Very clean and comfortable!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tamara CA $137 CA $154 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Davenport-Hotels-Hampton-Inn-Suites-Davenport.h1772036.Hotel-Information) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/60000/50600/50530/34a549a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/50600/50530/d8ddce4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/50600/50530/39704f43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Non Smoking](https://images.trvl-media.com/lodging/1000000/60000/50600/50530/28f9d757.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Davenport near I-80 Davenport 8.6/10 Excellent (300) "The room was comfortable & quiet. The staff was friendly with goid knowledge of the area for restaurants & shopping." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kris CA $99 CA $111 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Davenport-Hotels-Quality-Inn-Suites-Davenport-Near-I-80.h50530.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/30000000/29520000/29516100/29516073/b574df25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/30000000/29520000/29516100/29516073/w3837h2560x3y0-e17f6df7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/30000000/29520000/29516100/29516073/db4cbc45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/30000000/29520000/29516100/29516073/b1cd1e7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place East Moline Quad Cities East Moline 9.2/10 Wonderful (987) "Excellent condition, friendly staff, great rooftop bar." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $139 CA $156 total includes taxes & fees Dec 15 - Dec 16 [](https://www.expedia.ca/East-Moline-Hotels-Hyatt-Place-East-Moline-Quad-Cities.h29516073.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1690000/1683000/1682934/fb09d4cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1690000/1683000/1682934/ecf2be7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast on weekends](https://images.trvl-media.com/lodging/2000000/1690000/1683000/1682934/w2879h1920x1y0-6d3f2881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1690000/1683000/1682934/66a0d0ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Davenport - Quad Cities Davenport 8.8/10 Excellent (1003) "Nice hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristina CA $103 CA $115 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Davenport-Hotels-Comfort-Inn-Suites-Davenport-Quad-Cities.h1682934.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1370000/1364000/1363998/14573bee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1370000/1364000/1363998/0f804455.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Single Room, 1 King Bed, Hot Tub](https://images.trvl-media.com/lodging/2000000/1370000/1364000/1363998/3a871449.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/2000000/1370000/1364000/1363998/68f711dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stoney Creek Hotel Quad Cities - Moline Moline 8.4/10 Very good (1088) "Front desk staff were friendly very helpful and the room was clean and plenty of parking in area." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Perry CA $124 CA $141 total includes taxes & fees Dec 9 - Dec 10 [](https://www.expedia.ca/Moline-Hotels-Stoney-Creek-Hotel-Quad-Cities-Moline.h1363998.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-22&endDate=2025-12-23®ionId=603001&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Quad Cities Hotel Reviews ![Hotel Blackhawk, Autograph Collection](https://images.trvl-media.com/lodging/1000000/30000/26400/26385/1d458afa_y.jpg) ### Hotel Blackhawk, Autograph Collection 10/10 Excellent "We didnt have breakfast " [](https://expedia.ca/Davenport-Hotels-Hotel-Blackhawk.h26385.Hotel-Information) ![Wyndham Moline on John Deere Commons](https://images.trvl-media.com/lodging/1000000/50000/43400/43329/bc3dbe4c_y.jpg) ### Wyndham Moline on John Deere Commons 10/10 Excellent "Very happy with my stay. The room was very clean. Bathroom needs a little update, but was clean. Bed and linens were luxurious. Service was excellent all the way around. Free breakfast was terrific. Lots of choices. Parking was great. Wonderful location. Will stay there again. " [](https://expedia.ca/Moline-Hotels-Radisson-On-John-Deere-Commons-Moline.h43329.Hotel-Information) ![Sleep Inn & Suites Davenport - Quad Cities](https://images.trvl-media.com/lodging/1000000/900000/890800/890745/e44b240f_y.jpg) ### Sleep Inn & Suites Davenport - Quad Cities 10/10 Excellent "Very nice. Bed looked “iffy” in terms of comfort but was great. Service is amazing from the super pleasant woman that check us in to the gentleman that helped serve breakfast. He was very friendly and made sure to check on everyone to make sure they had good. Will definitely come back and 100% recommend!" [](https://expedia.ca/Davenport-Hotels-Sleep-Inn-Suites-Davenport-Quad-Cities.h890745.Hotel-Information) ![DoubleTree by Hilton Davenport](https://images.trvl-media.com/lodging/1000000/30000/28200/28199/w3839h2586x0y0-7ce07d45_y.jpg) ### DoubleTree by Hilton Davenport 10/10 Excellent "Great downtown location. Very friendly staff. " [](https://expedia.ca/Davenport-Hotels-DoubleTree-By-Hilton-Davenport.h28199.Hotel-Information) ![La Quinta Inn by Wyndham Davenport & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/6100/6063/8e5f2e52_y.jpg) ### La Quinta Inn by Wyndham Davenport & Conference Center 10/10 Excellent "We had to check out 2 days early due to the impending winter storm. We were told we would likely get a refund for the 2 nights we couldn't stay. Can someone let me know if that is the case and when we will get the refund?" [](https://expedia.ca/Davenport-Hotels-La-Quinta-Inn-By-Wyndham-Davenport-Conference-Center.h6063.Hotel-Information) ![Country Inn & Suites by Radisson, Moline Airport, IL](https://images.trvl-media.com/lodging/1000000/450000/445600/445572/f9a46e6b_y.jpg) ### Country Inn & Suites by Radisson, Moline Airport, IL 10/10 Excellent "Staff was very friendly and accommodating with service. Clean rooms and close to airport." [](https://expedia.ca/Moline-Hotels-Country-Inn-Suites-By-Radisson.h445572.Hotel-Information) ![Stoney Creek Hotel Quad Cities - Moline](https://images.trvl-media.com/lodging/2000000/1370000/1364000/1363998/14573bee_y.jpg) ### Stoney Creek Hotel Quad Cities - Moline 10/10 Excellent "Breakfast was hot and fresh comfy rooms " [](https://expedia.ca/Moline-Hotels-Stoney-Creek-Hotel-Quad-Cities-Moline.h1363998.Hotel-Information) ![Isle Casino Hotel - Bettendorf](https://images.trvl-media.com/lodging/2000000/1780000/1771100/1771006/dcb75544_y.jpg) ### Isle Casino Hotel - Bettendorf 10/10 Excellent "Great room, courteous staff." [](https://expedia.ca/Bettendorf-Hotels-Isle-Casino-Hotel-Bettendorf.h1771006.Hotel-Information) ![Best Western Plus Steeplegate Inn](https://images.trvl-media.com/lodging/1000000/10000/8300/8203/8bde8192_y.jpg) ### Best Western Plus Steeplegate Inn 10/10 Excellent "Clean room, staff very friendly and helpful, breakfast was very good. Lots of close parking." [](https://expedia.ca/Davenport-Hotels-Best-Western-Plus-Steeplegate-Inn.h8203.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Quad Cities cost? ### What are the best business-friendly hotels in Quad Cities? ### How many business-friendly hotels are there in Quad Cities? ### What are the best cheap business-friendly hotels in Quad Cities? ### Are there any family-friendly hotels in Quad Cities that are also business friendly? ### Are there any 5-star business-friendly hotels in Quad Cities? ### Why book your business-friendly hotel in Quad Cities with Expedia? ### How can I find cheap business-friendly hotels in Quad Cities? ### What is there to do in Quad Cities near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [1 Star Hotels in Historic Route 66 ](https://www.expedia.ca/1Star-Historic-Route-66-Hotels.s10-0-d702654640613646336.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Historic Route 66 ](https://www.expedia.ca/2Star-Historic-Route-66-Hotels.s20-0-d702654640613646336.Travel-Guide-Filter-Hotels) - [Aparthotels in Historic Route 66 ](https://www.expedia.ca/Historic-Route-66-Apart-Hotels.d702654640613646336-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Historic Route 66 ](https://www.expedia.ca/Historic-Route-66-Bed-And-Breakfast.d702654640613646336-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cabin Rentals in Historic Route 66 ](https://www.expedia.ca/Historic-Route-66-Cabins.d702654640613646336-aaCabins.Travel-Guide-Accommodation) - [Chalets in Historic Route 66 ](https://www.expedia.ca/Historic-Route-66-Chalets.d702654640613646336-aaChalets.Travel-Guide-Accommodation) - [Condo Rentals in Historic Route 66 ](https://www.expedia.ca/Historic-Route-66-Condos.d702654640613646336-aaCondos.Travel-Guide-Accommodation) - [Cottages in Historic Route 66 ](https://www.expedia.ca/Historic-Route-66-Cottages.d702654640613646336-aaCottages.Travel-Guide-Accommodation) - [Hostels in Historic Route 66 ](https://www.expedia.ca/Historic-Route-66-Hostels.d702654640613646336-aaHostels.Travel-Guide-Accommodation) - [Cheap Hotels in Historic Route 66 ](https://www.expedia.ca/Historic-Route-66-Hotels-Cheap-Hotels.0-0-d702654640613646336-tCheapHotels.Travel-Guide-Filter-Hotels) - [Club Quarters Hotels in Historic Route 66 ](https://www.expedia.ca/Historic-Route-66-Hotels-Club-Quarters.0-0-d702654640613646336--bClubQuarters.Travel-Guide-Filter-Hotels) - [Kimpton Hotels in Historic Route 66 ](https://www.expedia.ca/Historic-Route-66-Hotels-Kimpton-Hotels.0-0-d702654640613646336--bKimptonHotels.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Historic Route 66 ](https://www.expedia.ca/Historic-Route-66-Hotels-Luxury-Hotel.0-0-d702654640613646336-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Motel 6 Hotels in Historic Route 66 ](https://www.expedia.ca/Historic-Route-66-Hotels-Motel-6.0-0-d702654640613646336--bMotel6.Travel-Guide-Filter-Hotels) - [Red Roof Inn Hotels in Historic Route 66 ](https://www.expedia.ca/Historic-Route-66-Hotels-Red-Roof-Inn.0-0-d702654640613646336--bRedRoofInn.Travel-Guide-Filter-Hotels) - [Sonesta Hotel in Historic Route 66 ](https://www.expedia.ca/Historic-Route-66-Hotels-Sonesta-Hotel.0-0-d702654640613646336--bSonestaHotel.Travel-Guide-Filter-Hotels) - [Wyndham Extra Holidays Hotels in Historic Route 66 ](https://www.expedia.ca/Historic-Route-66-Hotels-Wyndham-Extra-Holidays.0-0-d702654640613646336--bWyndhamExtraHolidays.Travel-Guide-Filter-Hotels) - [Historic Route 66 Hotels ](https://www.expedia.ca/Historic-Route-66-Hotels.d702654640613646336.Travel-Guide-Hotels) - [Inns in Historic Route 66 ](https://www.expedia.ca/Historic-Route-66-Inns.d702654640613646336-aaInns.Travel-Guide-Accommodation) - [Lodges in Historic Route 66 ](https://www.expedia.ca/Historic-Route-66-Lodges.d702654640613646336-aaLodges.Travel-Guide-Accommodation) - [Motels in Historic Route 66 ](https://www.expedia.ca/Historic-Route-66-Motels.d702654640613646336-aaMotels.Travel-Guide-Accommodation) - [Resorts in Historic Route 66 ](https://www.expedia.ca/Historic-Route-66-Resort-Hotels.d702654640613646336-aaResortHotels.Travel-Guide-Accommodation) - [Hotels near Mississippi River ](https://www.expedia.ca/Mississippi-River-Hotels.0-l6209928-0.Travel-Guide-Filter-Hotels) - [B&B in Southeast Iowa ](https://www.expedia.ca/Southeast-Iowa-Bed-And-Breakfast.d6234151-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Americinn Hotels in Southeast Iowa ](https://www.expedia.ca/Southeast-Iowa-Hotels-Americinn.0-0-d6234151--bAmericinn.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Southeast Iowa ](https://www.expedia.ca/Southeast-Iowa-Hotels-Luxury-Hotel.0-0-d6234151-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Southeast Iowa ](https://www.expedia.ca/Southeast-Iowa-Hotels-Pet-Friendly-Hotel.0-0-d6234151-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Southeast Iowa ](https://www.expedia.ca/Southeast-Iowa-Hotels-Romantic-Hotel.0-0-d6234151-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Southeast Iowa Hotels ](https://www.expedia.ca/Southeast-Iowa-Hotels.d6234151.Travel-Guide-Hotels) - [Flights to Historic Route 66 ](https://www.expedia.ca/Cheap-Flights-To-Historic-Route-66.d702654640613646336.Travel-Guide-Flights) - [Flights to Southeast Iowa ](https://www.expedia.ca/Cheap-Flights-To-Southeast-Iowa.d6234151.Travel-Guide-Flights) - [Flights from Phoenix to Historic Route 66 ](https://www.expedia.ca/lp/flights/178298/702654640613646336/phoenix-to-historic-route-66) - [Historic Route 66 Vacations ](https://www.expedia.ca/Historic-Route-66.d702654640613646336.Destination-Travel-Guides) - [Mississippi River ](https://www.expedia.ca/Mississippi-River-United-States-of-America.d6209928.Vacation-Attraction) - [Visit Southeast Iowa ](https://www.expedia.ca/Southeast-Iowa.dx6234151) - [Ada Rental Cars in Historic Route 66 ](https://www.expedia.ca/ADA-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1109.Car-Rental-Guide-Suppliers) - [Airport Van Rental Rental Cars in Historic Route 66 ](https://www.expedia.ca/Airport-Van-Rental-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1092.Car-Rental-Guide-Suppliers) - [Amigo Autos Rental Cars in Historic Route 66 ](https://www.expedia.ca/Amigo-Autos-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1128.Car-Rental-Guide-Suppliers) - [Avis Rental Cars in Historic Route 66 ](https://www.expedia.ca/Avis-Car-Rentals-In-Historic-Route-66.d702654640613646336-c41.Car-Rental-Guide-Suppliers) - [Car rentals near Historic Route 66 ](https://www.expedia.ca/Car-Rentals-In-Historic-Route-66.d702654640613646336.Car-Rental-Guide) - [Click & Rent Rental Cars in Historic Route 66 ](https://www.expedia.ca/Click-Rent-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1089.Car-Rental-Guide-Suppliers) - [Convertible Car Rentals in Historic Route 66 ](https://www.expedia.ca/Convertible-Car-Rentals-In-Historic-Route-66.d702654640613646336-tConvertible.Car-Rental-Guide-Class) - [Drive-A-Matic Rental Cars in Historic Route 66 ](https://www.expedia.ca/Drive-A-Matic-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1082.Car-Rental-Guide-Suppliers) - [Drive on Holidays Rental Cars in Historic Route 66 ](https://www.expedia.ca/Drive-On-Holidays-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1050.Car-Rental-Guide-Suppliers) - [Firefly Rental Cars in Historic Route 66 ](https://www.expedia.ca/Firefly-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1040.Car-Rental-Guide-Suppliers) - [Firefly Portugal Rental Cars in Historic Route 66 ](https://www.expedia.ca/Firefly-Portugal-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1071.Car-Rental-Guide-Suppliers) - [First Car Rental Rental Cars in Historic Route 66 ](https://www.expedia.ca/First-Car-Rental-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1107.Car-Rental-Guide-Suppliers) - [Hertz Rental Cars in Historic Route 66 ](https://www.expedia.ca/Hertz-Car-Rentals-In-Historic-Route-66.d702654640613646336-c40.Car-Rental-Guide-Suppliers) - [Jumbo Car Rental Cars in Historic Route 66 ](https://www.expedia.ca/Jumbo-Car-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1067.Car-Rental-Guide-Suppliers) - [Luxury Car Rentals in Historic Route 66 ](https://www.expedia.ca/Luxury-Car-Rentals-In-Historic-Route-66.d702654640613646336-tLuxury.Car-Rental-Guide-Class) - [Midway Car Rental Rental Cars in Historic Route 66 ](https://www.expedia.ca/Midway-Car-Rental-Car-Rentals-In-Historic-Route-66.d702654640613646336-c27.Car-Rental-Guide-Suppliers) - [National Car Rental Rental Cars in Historic Route 66 ](https://www.expedia.ca/National-Car-Rental-Car-Rentals-In-Historic-Route-66.d702654640613646336-c42.Car-Rental-Guide-Suppliers) - [Offer Car Hire Rental Cars in Historic Route 66 ](https://www.expedia.ca/Offer-Car-Hire-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1141.Car-Rental-Guide-Suppliers) - [Orlando Rental Cars in Historic Route 66 ](https://www.expedia.ca/Orlando-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1047.Car-Rental-Guide-Suppliers) - [Pickup Car Rentals in Historic Route 66 ](https://www.expedia.ca/Pickup-Car-Rentals-In-Historic-Route-66.d702654640613646336-tPickup.Car-Rental-Guide-Class) - [Priceless Car Rental Rental Cars in Historic Route 66 ](https://www.expedia.ca/Priceless-Car-Rental-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1060.Car-Rental-Guide-Suppliers) - [Rent A Wreck Rental Cars in Historic Route 66 ](https://www.expedia.ca/Rent-A-Wreck-Car-Rentals-In-Historic-Route-66.d702654640613646336-c33.Car-Rental-Guide-Suppliers) - [Routes Rental Cars in Historic Route 66 ](https://www.expedia.ca/Routes-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1101.Car-Rental-Guide-Suppliers) - [Thai Cars Rental Cars in Historic Route 66 ](https://www.expedia.ca/Thai-Cars-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1027.Car-Rental-Guide-Suppliers) - [Thrifty Car Rental Rental Cars in Historic Route 66 ](https://www.expedia.ca/Thrifty-Car-Rental-Car-Rentals-In-Historic-Route-66.d702654640613646336-c45.Car-Rental-Guide-Suppliers) - [Van Car Rentals in Historic Route 66 ](https://www.expedia.ca/Van-Car-Rentals-In-Historic-Route-66.d702654640613646336-tVan.Car-Rental-Guide-Class) - [Wiber Rental Cars in Historic Route 66 ](https://www.expedia.ca/WIber-Car-Rentals-In-Historic-Route-66.d702654640613646336-c1127.Car-Rental-Guide-Suppliers) - [Historic Route 66 Vacation Rentals ](https://www.expedia.ca/Historic-Route-66-Vacation-Rentals.d702654640613646336.Travel-Guide-VacationRentals) - [Book Business Hotels in Quad Cities on Expedia.com ](https://www.expedia.com/Quad-Cities-Hotels-Business-Hotel.0-0-d603001-tBusinessHotel.Travel-Guide-Filter-Hotels)