Title: 10 Best Hotels in Puerto Santa Ana, Guayaquil for 2025 | Expedia.ca [Puerto Santa Ana Travel Guide](https://expedia.ca/Guayaquil-Puerto-Santa-Ana.dx6338310)[Vacation Rentals in Guayaquil](https://expedia.ca/Guayaquil-Vacation-Rentals.d1414.Travel-Guide-VacationRentals)[Flights to Guayaquil](https://expedia.ca/Cheap-Flights-To-Guayaquil.d1414.Travel-Guide-Flights)[Things to do in Guayaquil](https://expedia.ca/Things-To-Do-In-Guayaquil.d1414.Travel-Guide-Activities)[Puerto Santa Ana Car Rentals](https://expedia.ca/Car-Rentals-In-Puerto-Santa-Ana.d6338310.Car-Rental-Guide)[Puerto Santa Ana Vacations](https://expedia.ca/Puerto-Santa-Ana.d6338310.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Hotels in Puerto Santa Ana, Guayaquil ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Puerto Santa Ana Spa [](https://www.expedia.ca/Hotel-Search?destination=Puerto+Santa+Ana%2C+Guayaquil%2C+Guayas%2C+Ecuador®ionId=6338310&latLong=-2.177141%2C-79.876532&adults=2&startDate=2025-10-16&d1=2025-10-16&endDate=2025-10-18&d2=2025-10-18&amenities=SPA_ON_SITE) Apart hotel [](https://www.expedia.ca/Hotel-Search?destination=Puerto+Santa+Ana%2C+Guayaquil%2C+Guayas%2C+Ecuador®ionId=6338310&latLong=-2.177141%2C-79.876532&adults=2&startDate=2025-10-16&d1=2025-10-16&endDate=2025-10-18&d2=2025-10-18&lodging=APART_HOTEL) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Puerto+Santa+Ana%2C+Guayaquil%2C+Guayas%2C+Ecuador®ionId=6338310&latLong=-2.177141%2C-79.876532&adults=2&startDate=2025-10-16&d1=2025-10-16&endDate=2025-10-18&d2=2025-10-18&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=Puerto+Santa+Ana%2C+Guayaquil%2C+Guayas%2C+Ecuador®ionId=6338310&latLong=-2.177141%2C-79.876532&adults=2&startDate=2025-10-16&d1=2025-10-16&endDate=2025-10-18&d2=2025-10-18&amenities=POOL) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Puerto+Santa+Ana%2C+Guayaquil%2C+Guayas%2C+Ecuador®ionId=6338310&latLong=-2.177141%2C-79.876532&adults=2&startDate=2025-10-16&d1=2025-10-16&endDate=2025-10-18&d2=2025-10-18&lodging=APARTMENT) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Puerto+Santa+Ana%2C+Guayaquil%2C+Guayas%2C+Ecuador®ionId=6338310&latLong=-2.177141%2C-79.876532&adults=2&startDate=2025-10-16&d1=2025-10-16&endDate=2025-10-18&d2=2025-10-18&amenities=HOT_TUB) Condo [](https://www.expedia.ca/Hotel-Search?destination=Puerto+Santa+Ana%2C+Guayaquil%2C+Guayas%2C+Ecuador®ionId=6338310&latLong=-2.177141%2C-79.876532&adults=2&startDate=2025-10-16&d1=2025-10-16&endDate=2025-10-18&d2=2025-10-18&lodging=CONDO) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Puerto+Santa+Ana%2C+Guayaquil%2C+Guayas%2C+Ecuador®ionId=6338310&latLong=-2.177141%2C-79.876532&adults=2&startDate=2025-10-16&d1=2025-10-16&endDate=2025-10-18&d2=2025-10-18&amenities=PETS) ## Check prices for these dates Tonight [Oct 1 - Oct 2](https://www.expedia.ca/Hotel-Search?regionId=6338310&startDate=2025-10-01&endDate=2025-10-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 2 - Oct 3](https://www.expedia.ca/Hotel-Search?regionId=6338310&startDate=2025-10-02&endDate=2025-10-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6338310&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6338310&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Puerto Santa Ana hotels and places to stay ![Outdoor pool](https://images.trvl-media.com/lodging/23000000/22660000/22652600/22652575/b3ec1eca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Suite, 1 Bedroom](https://images.trvl-media.com/lodging/23000000/22660000/22652600/22652575/ea95563d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Suite, 1 Bedroom | Living room](https://images.trvl-media.com/lodging/23000000/22660000/22652600/22652575/ca36f487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/23000000/22660000/22652600/22652575/1ace7a1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### River View suites Puerto Santa Ana gye Puerto Santa Ana 8.4/10 Very good (37) "The staff were soo nice with me and my family !! I really enjoy my stay :)" CA $112 CA $113 total Oct 3 - Oct 4 [](https://www.expedia.ca/Guayaquil-Hotels-River-View-Suites-Puerto-Santa-Ana-Gye.h22652575.Hotel-Information) ![43-inch flat-screen TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/33000000/32050000/32048100/32048032/42319f76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Apartment, 2 Bedrooms, Kitchen, Hill View (2 Bedrooms with 3 Beds) | Private kitchen](https://images.trvl-media.com/lodging/33000000/32050000/32048100/32048032/e88f5dd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/33000000/32050000/32048100/32048032/6c4f3ade.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Apartment, 2 Bedrooms, Kitchen, Hill View (2 Bedrooms with 3 Beds) | Living area](https://images.trvl-media.com/lodging/33000000/32050000/32048100/32048032/332f0478.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury Suites Riverfront GYE Puerto Santa Ana 9.4/10 Exceptional (95) "Beautiful view" [](https://www.expedia.ca/Guayaquil-Hotels-Luxury-Suites-Riverfront-GYE.h32048032.Hotel-Information) ![Presidential Suite, 1 King Bed, Jetted Tub, River View](https://images.trvl-media.com/lodging/7000000/6320000/6312500/6312483/79b2b000.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/7000000/6320000/6312500/6312483/bf4ba68b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 King Bed, Jetted Tub, River View](https://images.trvl-media.com/lodging/7000000/6320000/6312500/6312483/8315afb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/7000000/6320000/6312500/6312483/69ea8661.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Guayaquil Puerto Santa Ana Puerto Santa Ana 9.2/10 Wonderful (1012) "Very nice hotel " CA $153 CA $172 total Oct 12 - Oct 13 [](https://www.expedia.ca/Guayaquil-Hotels-Wyndham-Guayaquil.h6312483.Hotel-Information) ![Apartment, 1 Bedroom | Terrace/patio](https://images.trvl-media.com/lodging/39000000/38030000/38028100/38028039/7a82f9a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/39000000/38030000/38028100/38028039/198e174a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 Bedroom | Living area](https://images.trvl-media.com/lodging/39000000/38030000/38028100/38028039/a859869c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/39000000/38030000/38028100/38028039/50834064.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NCG Suite Samanes 1 8.2 km from Puerto Santa Ana 6.0/10 (2) "Terrible,sorry I didn’t do my research on this place. No hot water and air conditioner worked when it wanted." CA $44 CA $45 total Oct 5 - Oct 6 [](https://www.expedia.ca/Guayaquil-Hotels-NCG-Suite-Samanes-1.h38028039.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/39000000/38030000/38028100/38028078/2dc50b33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms | Living area](https://images.trvl-media.com/lodging/39000000/38030000/38028100/38028078/74962654.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms](https://images.trvl-media.com/lodging/39000000/38030000/38028100/38028078/6b7630e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms | Dining room](https://images.trvl-media.com/lodging/39000000/38030000/38028100/38028078/42faf542.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NCG Suite Samanes 2 8.2 km from Puerto Santa Ana 8.8/10 Excellent (3) "Propiedad segura, ordenada, limpia y tranquila." CA $45 CA $47 total Oct 4 - Oct 5 [](https://www.expedia.ca/Guayaquil-Hotels-NCG-Suite-Samanes-2.h38028078.Hotel-Information) ![Family Studio Suite, 1 Bedroom, Private Bathroom](https://images.trvl-media.com/lodging/16000000/15830000/15824400/15824334/e56bced4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 Double Bed, Kitchenette | Private kitchenette](https://images.trvl-media.com/lodging/16000000/15830000/15824400/15824334/1ee38dd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/16000000/15830000/15824400/15824334/a27d1c14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/16000000/15830000/15824400/15824334/07773d1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Francisco Apart Hotel La Atarazana, 1.4 km from Puerto Santa Ana 6.2/10 (23) "Receptionist was very helpful finding us delivery food on arrival." CA $49 CA $50 total Oct 3 - Oct 4 [](https://www.expedia.ca/Guayaquil-Hotels-San-Francisco-Apart-Hotel.h15824334.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/4000000/3090000/3081200/3081144/fee31467.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/4000000/3090000/3081200/3081144/672aeff9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and lunch served](https://images.trvl-media.com/lodging/4000000/3090000/3081200/3081144/cf3efa1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Quadruple Room](https://images.trvl-media.com/lodging/4000000/3090000/3081200/3081144/fc65cf90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Guayaquil Hostel Suites Madrid 1.7 km from Puerto Santa Ana 7.2/10 Good (31) "noisy and dark but friendly staff central location" CA $52 CA $53 total Oct 3 - Oct 4 [](https://www.expedia.ca/Guayaquil-Hotels-Guayaquil-Hostel-Suites-Madrid.h3081144.Hotel-Information) ![Deluxe Apartment | Dining room](https://images.trvl-media.com/lodging/67000000/66420000/66414400/66414321/2fff35c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment | Bathroom](https://images.trvl-media.com/lodging/67000000/66420000/66414400/66414321/3aa5168b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/67000000/66420000/66414400/66414321/db6a880a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Land view from property](https://images.trvl-media.com/lodging/67000000/66420000/66414400/66414321/a7a3864f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NCG Suite Centro 9 de Octubre - 2 1.7 km from Puerto Santa Ana CA $53 CA $82 total Oct 10 - Oct 11 [](https://www.expedia.ca/Guayaquil-Hotels-NCG-Suite-Centro-9-De-Octubre-2.h66414321.Hotel-Information) ![Twin Room, 2 Queen Beds](https://images.trvl-media.com/lodging/13000000/12260000/12254300/12254205/bb5dd424.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/13000000/12260000/12254300/12254205/181e2972.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Elevator](https://images.trvl-media.com/lodging/13000000/12260000/12254300/12254205/9669ca5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/13000000/12260000/12254300/12254205/74e2f730.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Presidente Internacional 1.6 km from Puerto Santa Ana 6.0/10 (27) CA $48 CA $62 total Oct 17 - Oct 18 [](https://www.expedia.ca/Guayaquil-Hotels-Hotel-Presidente-Internacional.h12254205.Hotel-Information) ![6 bedrooms, in-room safe, free WiFi](https://images.trvl-media.com/lodging/100000000/99980000/99979800/99979748/9195a1a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![6 bedrooms, in-room safe, free WiFi](https://images.trvl-media.com/lodging/100000000/99980000/99979800/99979748/771f37a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Double Room](https://images.trvl-media.com/lodging/100000000/99980000/99979800/99979748/96f63d6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![6 bedrooms, in-room safe, free WiFi](https://images.trvl-media.com/lodging/100000000/99980000/99979800/99979748/8055c429.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Malecon Guesthouse River City, 1 km from Puerto Santa Ana CA $20 CA $35 total Oct 3 - Oct 4 [](https://www.expedia.ca/Guayaquil-Hotels-Malecon-Guesthouse.h99979748.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/6000000/5090000/5081300/5081291/fba8dafc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/6000000/5090000/5081300/5081291/6d158b88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/6000000/5090000/5081300/5081291/7194b01a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/6000000/5090000/5081300/5081291/137c415f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Fontana Hotel Downtown Guayaquil, 1.6 km from Puerto Santa Ana 8.0/10 Very good (108) "Room was excellent, service was excellent, Safe, easy check in-check out" CA $63 CA $63 total Oct 5 - Oct 6 [](https://www.expedia.ca/Guayaquil-Hotels-La-Fontana-Hotel.h5081291.Hotel-Information) ![Outdoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/10000000/9700000/9694600/9694596/bdd76180.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee shop](https://images.trvl-media.com/lodging/10000000/9700000/9694600/9694596/73dc04a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/10000000/9700000/9694600/9694596/63e79c6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/10000000/9700000/9694600/9694596/cd1e8709.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cedros Inn Boutique Hotel Urdesa, 3.3 km from Puerto Santa Ana 8.4/10 Very good (78) "The staff went above and beyond to accommodate any special needs that we had. The place itself is clean and very beautiful. Great location, near many restaurants (and Chabad). 10/10 recommend booking your stay here. " CA $94 CA $105 total Oct 3 - Oct 4 [](https://www.expedia.ca/Guayaquil-Hotels-Cedros-Inn-Boutique-Hotel.h9694596.Hotel-Information) ![55-inch Smart TV with cable channels, TV, heated floors](https://images.trvl-media.com/lodging/95000000/94850000/94847000/94846964/a1c44ede.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room](https://images.trvl-media.com/lodging/95000000/94850000/94847000/94846964/9db0dfb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Room, Multiple Beds, Ensuite](https://images.trvl-media.com/lodging/95000000/94850000/94847000/94846964/1e4fb887.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/95000000/94850000/94847000/94846964/159d621b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Royalty Inn Simón Bolívar, 3.1 km from Puerto Santa Ana 8.6/10 Excellent (10) "Good for a single night stay , close to the airport and mall " CA $60 CA $90 total Oct 3 - Oct 4 [](https://www.expedia.ca/Guayaquil-Hotels-The-Royalty-Inn.h94846964.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/84000000/83920000/83919600/83919535/6a3f2cec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Twin Room, 2 Double Beds | Room amenity](https://images.trvl-media.com/lodging/84000000/83920000/83919600/83919535/84846b7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/84000000/83920000/83919600/83919535/764976b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/84000000/83920000/83919600/83919535/9f3eb4dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hostal California Inn 1.5 km from Puerto Santa Ana 8.6/10 Excellent (8) CA $43 CA $45 total Oct 13 - Oct 14 [](https://www.expedia.ca/Guayaquil-Hotels-Hostal-California-Inn.h83919535.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/102000000/101150000/101143800/101143744/0cf5013f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/102000000/101150000/101143800/101143744/c3cfefde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Honeymoon Double Room](https://images.trvl-media.com/lodging/102000000/101150000/101143800/101143744/803a66d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily continental breakfast (USD 3.50 per person)](https://images.trvl-media.com/lodging/102000000/101150000/101143800/101143744/6e6b0eb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HOTEL PERLA CENTRAL MALECON Downtown Guayaquil, 1.3 km from Puerto Santa Ana 7.6/10 Good (18) "Balcony view was very cool " CA $44 CA $44 total Oct 3 - Oct 4 [](https://www.expedia.ca/Guayaquil-Hotels-HOTEL-PERLA-CENTRAL-MALECON.h101143744.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/100000000/99240000/99230200/99230164/0892ed8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99240000/99230200/99230164/04ee1fe9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/100000000/99240000/99230200/99230164/7a998940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Twin Room | Bathroom](https://images.trvl-media.com/lodging/100000000/99240000/99230200/99230164/741c6108.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hostal Bicentenario Downtown Guayaquil, 1.5 km from Puerto Santa Ana 4.8/10 (3) "The gentleman that checked me and my family in was amazing. He helped me get my car parked in the designated parking area, got my wife hot water to wash our baby's bottles, printed up copies of receipts I needed for a U.S. Consulate interview and was a very nice and helpful to myself and my family." CA $50 CA $50 total Oct 12 - Oct 13 [](https://www.expedia.ca/Guayaquil-Hotels-Hostal-Bicentenario.h99230164.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/10000000/9550000/9542500/9542499/8325814e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/10000000/9550000/9542500/9542499/2abd3f02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/10000000/9550000/9542500/9542499/e319d286.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Double Room | Terrace/patio](https://images.trvl-media.com/lodging/10000000/9550000/9542500/9542499/8de7a8c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Iguanazu Bed & Breakfast 5.4 km from Puerto Santa Ana 9.2/10 Wonderful (46) "Swimming pool" CA $125 CA $143 total Oct 5 - Oct 6 [](https://www.expedia.ca/Guayaquil-Hotels-Iguanazu-Bed-Breakfast.h9542499.Hotel-Information) ![Deluxe Loft | Living area](https://images.trvl-media.com/lodging/97000000/96820000/96812600/96812586/bf18bfd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/97000000/96820000/96812600/96812586/c643cdd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, espresso maker, rice cooker](https://images.trvl-media.com/lodging/97000000/96820000/96812600/96812586/e27f0508.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Design Studio](https://images.trvl-media.com/lodging/97000000/96820000/96812600/96812586/f5aa049d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### PRAGA APARTMENTS Urdesa, 3.4 km from Puerto Santa Ana 9.2/10 Wonderful (12) "Great place to stay at " CA $41 CA $64 total Oct 5 - Oct 6 [](https://www.expedia.ca/Guayaquil-Hotels-PRAGA-APARTMENTS.h96812586.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/114000000/113770000/113765400/113765303/e7a717d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/114000000/113770000/113765400/113765303/28f7fd75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/114000000/113770000/113765400/113765303/4b92a37e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Soundproofing, free WiFi, bed sheets](https://images.trvl-media.com/lodging/114000000/113770000/113765400/113765303/663b517a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Río Guayas by Art Hotels Ecuador Las Peñas, 0.6 km from Puerto Santa Ana 10/10 Exceptional (1) "I absolutely loved my stay at Hotel Rio Guayas! The staff was incredibly kind, attentive, and made me feel truly welcome. One of the highlights was the stunning river view from the restaurant absolutely unforgettable. The hotel feels luxurious, with beautiful artwork and elegant decor throughout. Everything was spotless and comfortable. I highly recommend this place and would love to stay again! For Sureeee" CA $332 CA $369 total Oct 13 - Oct 14 [](https://www.expedia.ca/Guayaquil-Hotels-Hotel-Rio-Guayas.h113765303.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/108000000/107570000/107563000/107562960/842791f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/108000000/107570000/107563000/107562960/f2023d3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathroom](https://images.trvl-media.com/lodging/108000000/107570000/107563000/107562960/6d15e007.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Game room](https://images.trvl-media.com/lodging/108000000/107570000/107563000/107562960/f99a8b5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tropical Inn 4.5 km from Puerto Santa Ana 8.0/10 Very good (12) "for the price was good" CA $35 CA $35 total Oct 3 - Oct 4 [](https://www.expedia.ca/Guayaquil-Hotels-Tropical-Inn.h107562960.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-16&endDate=2025-10-17®ionId=6338310&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FPuerto-Santa-Ana-Guayaquil-Hotels.0-n6338310-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FPuerto-Santa-Ana-Guayaquil-Hotels.0-n6338310-0.Travel-Guide-Filter-Hotels) ## Where to stay in Puerto Santa Ana Find the best Puerto Santa Ana areas and neighborhoods for the activities you enjoy most. [Learn more about Puerto Santa Ana](https://www.expedia.ca/Guayaquil-Puerto-Santa-Ana.dx6338310) - Downtown Guayaquil - Ecuador - Kennedy - Urdesa - Garzota [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=6337572) ![Downtown Guayaquil map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:jfkLr%7BsfNws%40cOiEsJhA%7Bd%40vAcO%7EAoHsCi%40%7EMwf%40rWlJ%7Ch%40tO%7DXdgB&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=mdSkwd7I6AuoItRBFZtkeIEIKM8=) ### Downtown Guayaquil Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Central Market and Sports Federation of Guayas while you're in town. [See properties](https://www.expedia.ca/Hotel-Search?regionId=6337572) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976397513) ![Ecuador map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7E%60xLhvrfNgL%7DB%60BgFt%40DnAbAh%40ITPS%60%40pB%60BZYl%40Rg%40%5C%3FvB&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=ZL6Y2Y-aQNNjRqGxywjQPqX6b5A=) ### Ecuador Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976397513) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248633981744623) ![Kennedy map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:d%7CbLxnufNu%40YkJUz%40oGdLwWrh%40kf%40fE%7BBjHaBhpAoBv_%40t%40%60WhAsHp%5BhZaJzEfNQfDqCpAcNdL_RdH_FzFwSkE%7Dc%40cEiFiA%7BKo%40mYnI%7BUd%40yKbBmHBoB%60BmAN%7DAkAa%40_IeAiAqBU_A%7E%40c%40%60EwAbD%3F%7EFuCv%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=3oJajMvpc2e_dbI95d4cVf6dpLo=) ### Kennedy Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or Policentro while you're exploring the area. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248633981744623) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248633981744847) ![Urdesa map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7CcfLntwfNeTaRaHrMyHdAeB%7DD_BfBiCgPii%40dBg%5CiKbDad%40%7EMb%40rDsDfCoMtHfJ%7CE%7DAlEX%7EI_CdTY%7EImAjWiG%60%5EhDvg%40zJn%40nEi%40%60IeGlUmMxAkFbI_NxDEzH_ELkOmA%7DA%7EI&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=e-dmhG4bSTWpTqZi2Hum5Yb-EtM=) ### Urdesa Urdesa is well-liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to San Marino Mall or Policentro. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248633981744847) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248633981707957) ![Garzota map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:vibLlntfNsp%40ieBhGcFfF%7C%40%7Ee%40nQvFnAtHKlEnc%40cB%7EDbUhKiI%60Eod%40%7EX&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=F9IRf7cL8OreID4a_3-O8CerGHo=) ### Garzota The restaurants and shopping are a few reasons travelers visit Garzota. Though there aren't many top sights in the neighborhood, you can visit Mall del Sol Shopping Center and Plaza del Sol, a few notable attractions nearby. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248633981707957) ## Top Puerto Santa Ana Hotel Reviews ![Radisson Hotel Guayaquil](//images.trvl-media.com/lodging/20000000/19220000/19213600/19213532/d700f6bc_y.jpg) ### Radisson Hotel Guayaquil 10/10 Excellent "The best" [](https://expedia.ca/Guayaquil-Hotels-Radisson-Guayaquil.h19213532.Hotel-Information) ![Wyndham Guayaquil Puerto Santa Ana](//images.trvl-media.com/lodging/7000000/6320000/6312500/6312483/79b2b000_y.jpg) ### Wyndham Guayaquil Puerto Santa Ana 10/10 Excellent "Excelente hotel, valió cada centavo" [](https://expedia.ca/Guayaquil-Hotels-Wyndham-Guayaquil.h6312483.Hotel-Information) ![Ibis Styles El Malecon Guayaquil](//images.trvl-media.com/lodging/94000000/93850000/93845100/93845075/15fd17ab_y.jpg) ### Ibis Styles El Malecon Guayaquil 10/10 Excellent "Great location and great hotel " [](https://expedia.ca/Guayaquil-Hotels-Ibis-Styles-El-Malecon-Guayaquil.h93845075.Hotel-Information) ![Holiday Inn Guayaquil Airport by IHG](//images.trvl-media.com/lodging/6000000/5960000/5959100/5959068/15d3bf82_y.jpg) ### Holiday Inn Guayaquil Airport by IHG 10/10 Excellent "Excellent hotel with superb food and service. Shuttle service to and from airport a big plus. " [](https://expedia.ca/Guayaquil-Hotels-Holiday-Inn-Guayaquil-Airport.h5959068.Hotel-Information) ![Oro Verde Guayaquil](//images.trvl-media.com/lodging/1000000/30000/23700/23682/104d895f_y.jpg) ### Oro Verde Guayaquil 10/10 Excellent "The hotel was everything offered and more, the staff is extraordinary, from the outside security, front desk receptionists, servers throughout all the restaurants, housekeepers and more, these people know what it is to host. I’m planing my next trip to Ecuador and be certain that I won’t need to search for any other hotel, Oro Verde is it for me!!!" [](https://expedia.ca/Guayaquil-Hotels-Oro-Verde-Guayaquil.h23682.Hotel-Information) ![River View suites Puerto Santa Ana gye](//images.trvl-media.com/lodging/23000000/22660000/22652600/22652575/b3ec1eca_y.jpg) ### River View suites Puerto Santa Ana gye 10/10 Excellent "The staff were soo nice with me and my family !! I really enjoy my stay :)" [](https://expedia.ca/Guayaquil-Hotels-River-View-Suites-Puerto-Santa-Ana-Gye.h22652575.Hotel-Information) ![TRYP by Wyndham Guayaquil Airport](//images.trvl-media.com/lodging/5000000/4440000/4436100/4436047/a69cdc33_y.jpg) ### TRYP by Wyndham Guayaquil Airport 10/10 Excellent "Great hotel that never disappoints. The staff are all very friendly and welcoming and keep the hotel in great shape. The close proximity to the Mall del Sol allows us to pass time walking and shopping in our free time. The courtesy shuttle to the airport makes getting to/from our flights very easy." [](https://expedia.ca/Guayaquil-Hotels-TRYP-By-Wyndham-Guayaquil.h4436047.Hotel-Information) ![Wyndham Garden Guayaquil](//images.trvl-media.com/lodging/2000000/1280000/1273600/1273513/a22c50d5_y.jpg) ### Wyndham Garden Guayaquil 10/10 Excellent "Great service! Highly recommend " [](https://expedia.ca/Guayaquil-Hotels-Wyndham-Garden-Guayaquil.h1273513.Hotel-Information) ![Unipark by Oro Verde Hotels](//images.trvl-media.com/lodging/1000000/10000/4400/4375/0c30e684_y.jpg) ### Unipark by Oro Verde Hotels 10/10 Excellent "I enjoyed much my staying in this hotel." [](https://expedia.ca/Guayaquil-Hotels-Unipark-By-Oro-Verde-Hotels.h4375.Hotel-Information) ## Frequently asked questions ### What is the best area to stay in Puerto Santa Ana? > Tarqui is the best area to stay in Puerto Santa Ana for travellers looking to immerse themselves in the vibrant culture of Ecuador. This lively neighbourhood is a hub of activity, offering a blend of modern amenities and local charm. With its proximity to the scenic Guayas River, visitors can enjoy leisurely strolls along the waterfront, as well as access to delightful restaurants and cafes that showcase the region's culinary delights. > > > > For couples seeking a romantic escape, Tarqui provides a picturesque setting with its beautiful views and lively atmosphere. Sharing a meal at one of the many riverside eateries while watching the sunset can create unforgettable moments. The area's welcoming vibe and friendly locals only add to the experience, making it a great choice for couples looking to connect with each other and the local culture. > > > > Families will also find Tarqui appealing, as it offers plenty of options for entertainment and relaxation. Nearby parks and playgrounds provide spaces for children to play, while parents can enjoy exploring local markets or indulging in delicious street food. The variety of family-friendly activities ensures that everyone can create lasting memories together. ### When is the best time to go to Puerto Santa Ana? > The most popular time to visit Puerto Santa Ana is December, as the city comes alive with festive celebrations and warm, welcoming temperatures averaging around 26°C. This period is great for those who enjoy outdoor activities, such as exploring the vibrant riverside promenades and indulging in local culinary delights at open-air cafes. > > > > During the peak season from December to February, tourist activity is at its highest, with visitors flocking to enjoy the sunny weather and lively atmosphere. This is an ideal time for sightseeing, as you can easily explore the nearby attractions, from historic sites to contemporary art installations, all while basking in the pleasant, tropical climate. > > > > For couples and families alike, the festive spirit in December creates a magical backdrop for making cherished memories. The Christmas lights and decorations transform the city, and there are often cultural events, markets, and concerts that add to the experience. You can take leisurely strolls along the waterfront or relax in one of the city's beautiful parks, soaking in the vibrant surroundings. > > > > If you're looking for a more budget-friendly option, consider visiting in March. This month typically sees fewer tourists, allowing for a more tranquil experience while still enjoying the pleasant weather. You'll find that prices for accommodation and activities are often lower, providing excellent value without compromising on quality. ### Where can I find the best nightlife in Puerto Santa Ana? > Puerto Santa Ana, a charming riverside neighbourhood in Guayas, Ecuador, offers a delightful blend of relaxation and nightlife. > > > > The waterfront area is particularly lively, with a variety of bars and restaurants lining the banks of the Guayas River. Here, you can enjoy a vibrant atmosphere while sipping on cocktails or sampling local cuisine. The promenade is a popular spot for both locals and visitors, especially as the sun sets, creating a great backdrop for an evening out. > > > > For those seeking a more energetic nightlife experience, the nearby Las Peñas district is well-known for its vibrant bars and live music venues. This historic area is often filled with both tourists and locals, making it a great place to mingle and enjoy the nightlife. ### Can I cancel my hotel reservation on Expedia? > You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Puerto Santa Ana. ### How can I save on a Puerto Santa Ana hotel booking with Expedia? > Before booking your Puerto Santa Ana hotel, remember to join Expedia's free travel rewards program. Just sign up and sign in to access our lowest Member Prices as well as members-only perks. You could also enjoy savings by bundling together your hotel and flights on Expedia. ### How much is the nightly rate at a Puerto Santa Ana hotel? > Prices for hotels in Puerto Santa Ana often vary, but you can find a great deal on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [Buijo Histórico Hotels](https://www.expedia.ca/Buijo-Historico-Guayaquil-Hotels.0-n553248635976385128-0.Travel-Guide-Filter-Hotels) - [Chongón Hotels](https://www.expedia.ca/Chongon-Guayaquil-Hotels.0-n553248635976386577-0.Travel-Guide-Filter-Hotels) - [Daular Hotels](https://www.expedia.ca/Daular-Hotels.d553248635975864884.Travel-Guide-Hotels) - [Delia Hotels](https://www.expedia.ca/Delia-Guayaquil-Hotels.0-n553248635975855772-0.Travel-Guide-Filter-Hotels) - [Guayas Hotels](https://www.expedia.ca/Destinations-In-Guayas.d6239779.Hotel-Destinations) - [Lgbt Friendly Hotels in Downtown Guayaquil](https://www.expedia.ca/Downtown-Guayaquil-Guayaquil-Hotels-LGBT-Friendly-Hotel.0-n6337572-0-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - [Downtown Guayaquil Hotels](https://www.expedia.ca/Downtown-Guayaquil-Guayaquil-Hotels.0-n6337572-0.Travel-Guide-Filter-Hotels) - 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[Hotels in Urbanizacion Villa del Rey](https://expedia.ca/Urbanizacion-Villa-Del-Rey-Guayaquil-Hotels.0-n553248635976397967-0.Travel-Guide-Filter-Hotels) - [Hotels in Guayacanes](https://expedia.ca/Guayacanes-Guayaquil-Hotels.0-n553248635976384402-0.Travel-Guide-Filter-Hotels) - [Hotels in Parroquia Sucre](https://expedia.ca/Parroquia-Sucre-Guayaquil-Hotels.0-n553248635976389557-0.Travel-Guide-Filter-Hotels) - [Hotels in Sauce](https://expedia.ca/Sauce-Guayaquil-Hotels.0-n553248635975870044-0.Travel-Guide-Filter-Hotels) - [Hotels in Nueva Esperanza](https://expedia.ca/Nueva-Esperanza-Guayaquil-Hotels.0-n553248635976400709-0.Travel-Guide-Filter-Hotels) ### Hotels near popular Guayaquil Attractions - [Hotels near Malecon 2000](https://expedia.ca/Malecon-2000-Hotels.0-l6112432-0.Travel-Guide-Filter-Hotels) - [Hotels near Mall del Sol Shopping Center](https://expedia.ca/Mall-Del-Sol-Shopping-Center-Hotels.0-l6160670-0.Travel-Guide-Filter-Hotels) ### More Accommodation Types in Puerto Santa Ana - [Hostels in Guayaquil](https://expedia.ca/Guayaquil-Hostels.d1414-aaHostels.Travel-Guide-Accommodation) ### Hotels Close to Nearby Airports - [Hotels near Jose Joaquin de Olmedo Intl. 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