Title: 10 Best Hotels in Puerto Santa Ana, Guayaquil for 2026 | Expedia.ca [Puerto Santa Ana Travel Guide](https://expedia.ca/Guayaquil-Puerto-Santa-Ana.dx6338310)[Vacation Rentals in Guayaquil](https://expedia.ca/Guayaquil-Vacation-Rentals.d1414.Travel-Guide-VacationRentals)[Flights to Guayaquil](https://expedia.ca/Cheap-Flights-To-Guayaquil.d1414.Travel-Guide-Flights)[Things to do in Guayaquil](https://expedia.ca/Things-To-Do-In-Guayaquil.d1414.Travel-Guide-Activities)[Puerto Santa Ana Car Rentals](https://expedia.ca/Car-Rentals-In-Puerto-Santa-Ana.d6338310.Car-Rental-Guide)[Puerto Santa Ana Vacations](https://expedia.ca/Puerto-Santa-Ana.d6338310.Destination-Travel-Guides) ![Vista panorámica de las favelas de cerro santa ana, guayaquil, ecuador](https://images.trvl-media.com/place/6338310/7d2e991e-9428-4fdb-b585-549f29a51fa9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6338310/7d2e991e-9428-4fdb-b585-549f29a51fa9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 27 - Jan 28](https://www.expedia.ca/Hotel-Search?regionId=6338310&startDate=2026-01-27&endDate=2026-01-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 28 - Jan 29](https://www.expedia.ca/Hotel-Search?regionId=6338310&startDate=2026-01-28&endDate=2026-01-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=6338310&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6338310&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Puerto Santa Ana hotels ![Outdoor pool](https://images.trvl-media.com/lodging/23000000/22660000/22652600/22652575/b3ec1eca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/23000000/22660000/22652600/22652575/e4fb9cbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/23000000/22660000/22652600/22652575/a69fa43d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/23000000/22660000/22652600/22652575/6e6c8de6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### River View suites Puerto Santa Ana gye [](https://www.expedia.ca/Guayaquil-Hotels-River-View-Suites-Puerto-Santa-Ana-Gye.h22652575.Hotel-Information) Puerto Santa Ana 8.8/10 Excellent (46 reviews) "Nice place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aaliyah CA $110 CA $111 total Jan 30 - Jan 31 [](https://www.expedia.ca/Guayaquil-Hotels-River-View-Suites-Puerto-Santa-Ana-Gye.h22652575.Hotel-Information) ![Outdoor spa tub](https://images.trvl-media.com/lodging/33000000/32050000/32048100/32048032/04063cb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Suite, 1 Bedroom, Ensuite, Ground Floor | Private kitchen](https://images.trvl-media.com/lodging/33000000/32050000/32048100/32048032/f1ade29c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Apartment, 2 Bedrooms, River View, Ground Floor (2 Bedrooms with 3 Beds)](https://images.trvl-media.com/lodging/33000000/32050000/32048100/32048032/bb76d4b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/33000000/32050000/32048100/32048032/2cfaa3df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury Suites Riverfront GYE [](https://www.expedia.ca/Guayaquil-Hotels-Luxury-Suites-Riverfront-GYE.h32048032.Hotel-Information) Puerto Santa Ana 9.4/10 Exceptional (104 reviews) "The property was very clean and well maintained. Lots of security. The building is on the riverfront with many excellent restaurants within a few steps. Vibrant night life which was unfortunately very noisy when trying to sleep. Within walking distance to many attractions." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carolyn CA $143 CA $145 total Feb 8 - Feb 9 [](https://www.expedia.ca/Guayaquil-Hotels-Luxury-Suites-Riverfront-GYE.h32048032.Hotel-Information) ![2 bars/lounges, lobby lounge](https://images.trvl-media.com/lodging/7000000/6320000/6312500/6312483/007eb40d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; international cuisine](https://images.trvl-media.com/lodging/7000000/6320000/6312500/6312483/c2a9584b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/7000000/6320000/6312500/6312483/5192a920.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6320000/6312500/6312483/0ba4528e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Guayaquil Puerto Santa Ana [](https://www.expedia.ca/Guayaquil-Hotels-Wyndham-Guayaquil.h6312483.Hotel-Information) Puerto Santa Ana 9.2/10 Wonderful (1,011 reviews) "Clean rooms,great staff and very good food" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Abel Patricio CA $144 CA $162 total Feb 27 - Feb 28 [](https://www.expedia.ca/Guayaquil-Hotels-Wyndham-Guayaquil.h6312483.Hotel-Information) ![Junior Suite, 1 Double Bed, Kitchenette](https://images.trvl-media.com/lodging/16000000/15830000/15824400/15824334/e31d844c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/16000000/15830000/15824400/15824334/001711ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/16000000/15830000/15824400/15824334/a27d1c14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15830000/15824400/15824334/c5e333f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Francisco Apart Hotel [](https://www.expedia.ca/Guayaquil-Hotels-San-Francisco-Apart-Hotel.h15824334.Hotel-Information) La Atarazana, 1.4 km from Puerto Santa Ana 6.2/10 (23 reviews) "Receptionist was very helpful finding us delivery food on arrival." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William CA $47 CA $48 total Jan 30 - Jan 31 [](https://www.expedia.ca/Guayaquil-Hotels-San-Francisco-Apart-Hotel.h15824334.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/13000000/12260000/12254300/12254205/74e2f730.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, 1 Queen Bed](https://images.trvl-media.com/lodging/13000000/12260000/12254300/12254205/81fd579b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/13000000/12260000/12254300/12254205/181e2972.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Billiards](https://images.trvl-media.com/lodging/13000000/12260000/12254300/12254205/37338a8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Presidente Internacional [](https://www.expedia.ca/Guayaquil-Hotels-Hotel-Presidente-Internacional.h12254205.Hotel-Information) 1.6 km from Puerto Santa Ana 6.0/10 (27 reviews) "La ubicación es excelente. Cerca de todo " ![Colombia](https://a.travel-assets.com/egds/marks/flags/co.svg) Myriam [](https://www.expedia.ca/Guayaquil-Hotels-Hotel-Presidente-Internacional.h12254205.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/6000000/5090000/5081300/5081291/b3c96bc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/6000000/5090000/5081300/5081291/fba8dafc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/6000000/5090000/5081300/5081291/7194b01a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/6000000/5090000/5081300/5081291/6d158b88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Fontana Hotel [](https://www.expedia.ca/Guayaquil-Hotels-La-Fontana-Hotel.h5081291.Hotel-Information) Downtown Guayaquil, 1.6 km from Puerto Santa Ana 8.0/10 Very good (110 reviews) "Room was excellent, service was excellent, Safe, easy check in-check out" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Abraham [](https://www.expedia.ca/Guayaquil-Hotels-La-Fontana-Hotel.h5081291.Hotel-Information) ![Standard Double Room](https://images.trvl-media.com/lodging/100000000/99240000/99230200/99230164/4799647f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99240000/99230200/99230164/04ee1fe9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Quadruple Room | Bathroom](https://images.trvl-media.com/lodging/100000000/99240000/99230200/99230164/f2f45713.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/100000000/99240000/99230200/99230164/7a998940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hostal Bicentenario [](https://www.expedia.ca/Guayaquil-Hotels-Hostal-Bicentenario.h99230164.Hotel-Information) Downtown Guayaquil, 1.5 km from Puerto Santa Ana 6.0/10 (4 reviews) "The gentleman that checked me and my family in was amazing. He helped me get my car parked in the designated parking area, got my wife hot water to wash our baby's bottles, printed up copies of receipts I needed for a U.S. Consulate interview and was a very nice and helpful to myself and my family." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matthew [](https://www.expedia.ca/Guayaquil-Hotels-Hostal-Bicentenario.h99230164.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/84000000/83920000/83919600/83919535/6a3f2cec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![42-inch LED TV with cable channels, TV](https://images.trvl-media.com/lodging/84000000/83920000/83919600/83919535/ca8d631f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cooked-to-order breakfast on weekdays (USD 3.00 per person)](https://images.trvl-media.com/lodging/84000000/83920000/83919600/83919535/w1650h2440x0y0-e4b6bf85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Twin Room, 2 Double Beds | Room amenity](https://images.trvl-media.com/lodging/84000000/83920000/83919600/83919535/84846b7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hostal California Inn [](https://www.expedia.ca/Guayaquil-Hotels-Hostal-California-Inn.h83919535.Hotel-Information) 1.5 km from Puerto Santa Ana 8.6/10 Excellent (8 reviews) "Me encantó, es muy cómoda, la habitación super amplia y limpia Si duda volveré " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Anita [](https://www.expedia.ca/Guayaquil-Hotels-Hostal-California-Inn.h83919535.Hotel-Information) ![Outdoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/10000000/9700000/9694600/9694596/bdd76180.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/10000000/9700000/9694600/9694596/cd1e8709.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee shop](https://images.trvl-media.com/lodging/10000000/9700000/9694600/9694596/36e6a92f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/10000000/9700000/9694600/9694596/c397d5fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cedros Inn Boutique Hotel [](https://www.expedia.ca/Guayaquil-Hotels-Cedros-Inn-Boutique-Hotel.h9694596.Hotel-Information) Urdesa, 3.3 km from Puerto Santa Ana 8.6/10 Excellent (87 reviews) "Its a small and beatiful hotel, good location, nice and modern with excelent service. its a very good choice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) LIBARDO CA $85 CA $95 total Jan 28 - Jan 29 [](https://www.expedia.ca/Guayaquil-Hotels-Cedros-Inn-Boutique-Hotel.h9694596.Hotel-Information) ![Honeymoon Double Room](https://images.trvl-media.com/lodging/102000000/101150000/101143800/101143744/df985073.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily continental breakfast (USD 3.50 per person)](https://images.trvl-media.com/lodging/102000000/101150000/101143800/101143744/c02c00df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/102000000/101150000/101143800/101143744/9b7220bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/102000000/101150000/101143800/101143744/18ac1f6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HOTEL PERLA CENTRAL MALECON [](https://www.expedia.ca/Guayaquil-Hotels-HOTEL-PERLA-CENTRAL-MALECON.h101143744.Hotel-Information) Downtown Guayaquil, 1.3 km from Puerto Santa Ana 7.6/10 Good (18 reviews) "Balcony view was very cool " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julio CA $43 CA $43 total Jan 28 - Jan 29 [](https://www.expedia.ca/Guayaquil-Hotels-HOTEL-PERLA-CENTRAL-MALECON.h101143744.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/108000000/107570000/107563000/107562960/842791f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Single Room](https://images.trvl-media.com/lodging/108000000/107570000/107563000/107562960/bfddac3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/108000000/107570000/107563000/107562960/d9518297.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathroom](https://images.trvl-media.com/lodging/108000000/107570000/107563000/107562960/6d15e007.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tropical Inn [](https://www.expedia.ca/Guayaquil-Hotels-Tropical-Inn.h107562960.Hotel-Information) 4.5 km from Puerto Santa Ana 8.2/10 Very good (16 reviews) "for the price was good" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rosa [](https://www.expedia.ca/Guayaquil-Hotels-Tropical-Inn.h107562960.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/114000000/113770000/113765400/113765303/02d3f2d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Building design](https://images.trvl-media.com/lodging/114000000/113770000/113765400/113765303/aafff4e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/114000000/113770000/113765400/113765303/8d165df2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/114000000/113770000/113765400/113765303/fe038750.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Río Guayas by Art Hotels Ecuador [](https://www.expedia.ca/Guayaquil-Hotels-Hotel-Rio-Guayas.h113765303.Hotel-Information) Las Peñas, 0.6 km from Puerto Santa Ana 10/10 Exceptional (3 reviews) "The staff was very friendly and helpful. The hotel is new and modern, it is a good place to relax and work. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard CA $329 CA $368 total Jan 28 - Jan 29 [](https://www.expedia.ca/Guayaquil-Hotels-Hotel-Rio-Guayas.h113765303.Hotel-Information) ![Down comforters, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/13000000/12080000/12071400/12071303/cbd9e9a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/13000000/12080000/12071400/12071303/0f347336.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/13000000/12080000/12071400/12071303/7d880319.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/13000000/12080000/12071400/12071303/6b95e60b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Las Peñas [](https://www.expedia.ca/Guayaquil-Hotels-Hotel-Las-Penas.h12071303.Hotel-Information) Rocafuerte, 1.8 km from Puerto Santa Ana 8.4/10 Very good (104 reviews) "The air conditioning was great and the location was very good." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rommel CA $50 CA $52 total Jan 28 - Jan 29 [](https://www.expedia.ca/Guayaquil-Hotels-Hotel-Las-Penas.h12071303.Hotel-Information) ![Comfort Apartment, Kitchenette](https://images.trvl-media.com/lodging/115000000/114970000/114965400/114965387/e8be61a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Apartment, Kitchenette | Living area](https://images.trvl-media.com/lodging/115000000/114970000/114965400/114965387/ca79cfec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Apartment, Kitchenette | Private kitchen](https://images.trvl-media.com/lodging/115000000/114970000/114965400/114965387/772ab89e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Apartment, Kitchenette | Private kitchen](https://images.trvl-media.com/lodging/115000000/114970000/114965400/114965387/81f76e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Guayacan Apart Hotel [](https://www.expedia.ca/Guayaquil-Hotels-Guayacan-Apart-Hotel.h114965387.Hotel-Information) Downtown Guayaquil, 1.6 km from Puerto Santa Ana CA $55 CA $55 total Jan 30 - Jan 31 [](https://www.expedia.ca/Guayaquil-Hotels-Guayacan-Apart-Hotel.h114965387.Hotel-Information) ![Superior Double Room, 2 Single Beds](https://images.trvl-media.com/lodging/71000000/70590000/70585400/70585385/71b2444a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/71000000/70590000/70585400/70585385/b8060a30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Building design](https://images.trvl-media.com/lodging/71000000/70590000/70585400/70585385/4bd804bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/71000000/70590000/70585400/70585385/b3b565bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel GH Sander [](https://www.expedia.ca/Guayaquil-Hotels-Hotel-Sander.h70585385.Hotel-Information) Rocafuerte, 2.1 km from Puerto Santa Ana 8.6/10 Excellent (14 reviews) "great property. i would definitely come back again every time i come to guayaquil" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) George [](https://www.expedia.ca/Guayaquil-Hotels-Hotel-Sander.h70585385.Hotel-Information) ![Comfort Double Room](https://images.trvl-media.com/lodging/71000000/70590000/70585300/70585298/f72daf3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Limited parking](https://images.trvl-media.com/lodging/71000000/70590000/70585300/70585298/d5dd2c2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/71000000/70590000/70585300/70585298/558f15f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/71000000/70590000/70585300/70585298/9d558325.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel GH Alexander [](https://www.expedia.ca/Guayaquil-Hotels-Hotel-Alexander.h70585298.Hotel-Information) Rocafuerte, 2.1 km from Puerto Santa Ana 8.4/10 Very good (37 reviews) "Great value hot water clean friendly staff on site restaurant " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Monty [](https://www.expedia.ca/Guayaquil-Hotels-Hotel-Alexander.h70585298.Hotel-Information) ![Suite, Jetted Tub](https://images.trvl-media.com/lodging/16000000/15290000/15283400/15283367/a1125a0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/16000000/15290000/15283400/15283367/00aa7cbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/16000000/15290000/15283400/15283367/f410eab7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast (USD 3 per person)](https://images.trvl-media.com/lodging/16000000/15290000/15283400/15283367/19ea2f26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Varadero Internacional [](https://www.expedia.ca/Guayaquil-Hotels-Hotel-Varadero-Internacional.h15283367.Hotel-Information) Downtown Guayaquil, 1.7 km from Puerto Santa Ana 8.0/10 Very good (66 reviews) "Overall a good place to stay and close to most destinations." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daniel CA $37 CA $38 total Jan 31 - Feb 1 [](https://www.expedia.ca/Guayaquil-Hotels-Hotel-Varadero-Internacional.h15283367.Hotel-Information) ![Deluxe Studio Suite, Jetted Tub](https://images.trvl-media.com/lodging/93000000/92510000/92506600/92506511/939e8452.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/93000000/92510000/92506600/92506511/ba11c7b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/93000000/92510000/92506600/92506511/9c0b3d69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/93000000/92510000/92506600/92506511/0f33b121.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Sada [](https://www.expedia.ca/Guayaquil-Hotels-Hotel-Sada.h92506511.Hotel-Information) 1.5 km from Puerto Santa Ana 9.6/10 Exceptional (10 reviews) "La habitación impermeable y el personal excelente " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) JoseEliseo CA $49 CA $51 total Jan 28 - Jan 29 [](https://www.expedia.ca/Guayaquil-Hotels-Hotel-Sada.h92506511.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/30000000/29930000/29925900/29925872/80b7df2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Habitación cuádruple ejecutiva, dormitorio mixto, baño compartido, vistas a la ciudad (1)](https://images.trvl-media.com/lodging/30000000/29930000/29925900/29925872/2cf6a81f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/30000000/29930000/29925900/29925872/0e724d40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/30000000/29930000/29925900/29925872/8162a6a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villa Celeste - VC [](https://www.expedia.ca/Guayaquil-Hotels-Villa-Celeste-VC.h29925872.Hotel-Information) 4.9 km from Puerto Santa Ana 7.4/10 Good (13 reviews) "It is a good place, they respect your privacity and has a good communication with tourist places " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Moises Reque [](https://www.expedia.ca/Guayaquil-Hotels-Villa-Celeste-VC.h29925872.Hotel-Information) ![Ecotours](https://images.trvl-media.com/lodging/102000000/101760000/101750500/101750483/ca8ca9e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Twin Room, 2 Double Beds](https://images.trvl-media.com/lodging/102000000/101760000/101750500/101750483/16926df1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![45-inch Smart TV with digital channels, Netflix, streaming services](https://images.trvl-media.com/lodging/102000000/101760000/101750500/101750483/95188a3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/102000000/101760000/101750500/101750483/47dac461.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fortune Hotel [](https://www.expedia.ca/Guayaquil-Hotels-Fortune-Hotel.h101750483.Hotel-Information) River City, 1 km from Puerto Santa Ana 8.0/10 Very good (7 reviews) "Very bad Hotel. Not using Expedia again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bryan CA $62 CA $63 total Jan 28 - Jan 29 [](https://www.expedia.ca/Guayaquil-Hotels-Fortune-Hotel.h101750483.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-10&endDate=2026-02-11®ionId=6338310&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in Puerto Santa Ana Find the best Puerto Santa Ana areas and neighborhoods for the activities you enjoy most. [Learn more about Puerto Santa Ana](https://www.expedia.ca/Guayaquil-Puerto-Santa-Ana.dx6338310) - Ecuador - Downtown Guayaquil - Bolívar - Kennedy - Simón Bolívar [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976397513) ![Ecuador map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7E%60xLhvrfNgL%7DB%60BeFt%40BnAbAh%40ITPS%60%40pB%60BZYl%40Rg%40%5C%3FvB&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=ITAe6nXctcoLe9r_9tpkYiy1Tjw=) ### Ecuador Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976397513) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=6337572) ![Downtown Guayaquil map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:jfkLr%7BsfNws%40cOiEsJhA%7Bd%40vAcO%7EAoHqCi%40%7CMwf%40tWlJ%7Ch%40tO_YdgB&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=efYuk0Ril1wmcsuwYNvCseyS7mU=) ### Downtown Guayaquil Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like San Francisco Square and Central Market while you're in town. [See properties](https://www.expedia.ca/Hotel-Search?regionId=6337572) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=916425151487365120) ![Bolívar map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:jdmLtcsfNgm%40gMjCuSjp%40fEoFt%5B&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=asSonBXw-8et3K4FrN6CN5UpvUQ=) ### Bolívar While Bolívar isn't home to many top sights, Malecon Mall and San Francisco Square are some notable places to visit nearby. [See properties](https://www.expedia.ca/Hotel-Search?regionId=916425151487365120) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248633981744623) ![Kennedy map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:d%7CbLxnufNu%40YkJUz%40oGdLwWrh%40kf%40fE%7BBjHaBhpAoBv_%40t%40bWhAuHp%5BjZaJxEfNQfDqCpAcNdL_RfH_FxFwSkE%7Dc%40aEiFkA%7BKo%40kYnI%7DUd%40yKbBmHBoB%60BmAN%7DAkAa%40_IeAiAqBU_A%7E%40c%40%60EwAbD%3F%7EFuCv%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=XWwvskPj7fazk3NWYmm490jAt1Q=) ### Kennedy Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248633981744623) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976384862) ![Simón Bolívar map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%60%7BcLjqsfNaO%7BFsHgFdBqEsDm%5EYW%3FaA%5COrHiAjFKnDXfF%7EAxRtIhf%40zVc%5El%40sF%7E%40_HzCiD%7EDk%40HmEbE&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=qpnNaBPGUClPrWkhGP6-aHRquqw=) ### Simón Bolívar If you're spending some time in Simón Bolívar, Mall del Sol Shopping Center and Plaza del Sol are top sights worth seeing. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976384862) ## Top Puerto Santa Ana Hotel Reviews ![Oro Verde Guayaquil](https://images.trvl-media.com/lodging/1000000/30000/23700/23682/104d895f_y.jpg) ### Oro Verde Guayaquil 10/10 Excellent "Yes" [](https://expedia.ca/Guayaquil-Hotels-Oro-Verde-Guayaquil.h23682.Hotel-Information) ![Wyndham Garden Guayaquil](https://images.trvl-media.com/lodging/2000000/1280000/1273600/1273513/a22c50d5_y.jpg) ### Wyndham Garden Guayaquil 10/10 Excellent "The room was comfortable, the staff was friendly and efficient, the neighborhood felt safe because of the extra security everywhere, and it was a quick easy walk to the mall." [](https://expedia.ca/Guayaquil-Hotels-Wyndham-Garden-Guayaquil.h1273513.Hotel-Information) ![Grand Hotel Guayaquil, an Ascend Collection Hotel](https://images.trvl-media.com/lodging/7000000/6760000/6751000/6750908/1d447ff4_y.jpg) ### Grand Hotel Guayaquil, an Ascend Collection Hotel 10/10 Excellent "Everything was perfect " [](https://expedia.ca/Guayaquil-Hotels-Grand-Hotel-Guayaquil.h6750908.Hotel-Information) ![DC Suites Aeropuerto](https://images.trvl-media.com/lodging/18000000/17340000/17331400/17331318/2a010657_y.jpg) ### DC Suites Aeropuerto 10/10 Excellent "Wonderful lady at the front desk. Rooms are clean and lovely. Bathroom is immaculate. Close to many local restaurants and a mall. " [](https://expedia.ca/Guayaquil-Hotels-DC-Suites-Aeropuerto.h17331318.Hotel-Information) ![Holiday Inn Guayaquil Airport by IHG](https://images.trvl-media.com/lodging/6000000/5960000/5959100/5959068/15d3bf82_y.jpg) ### Holiday Inn Guayaquil Airport by IHG 10/10 Excellent "Excellent volveria sin Pensarlo " [](https://expedia.ca/Guayaquil-Hotels-Holiday-Inn-Guayaquil-Airport.h5959068.Hotel-Information) ![Hilton Colon Guayaquil](https://images.trvl-media.com/lodging/1000000/70000/69100/69054/de7e624e_y.jpg) ### Hilton Colon Guayaquil 10/10 Excellent "Yes" [](https://expedia.ca/Guayaquil-Hotels-Hilton-Colon-Guayaquil.h69054.Hotel-Information) ![TRYP by Wyndham Guayaquil Airport](https://images.trvl-media.com/lodging/5000000/4440000/4436100/4436047/26f25154_y.jpg) ### TRYP by Wyndham Guayaquil Airport 10/10 Excellent "The hotel is very good, the service is excellent, I highly recommend it, one of the best hotels. " [](https://expedia.ca/Guayaquil-Hotels-TRYP-By-Wyndham-Guayaquil.h4436047.Hotel-Information) ![Hotel Puerto Pacifico Guayaquil Airport](https://images.trvl-media.com/lodging/49000000/48230000/48220700/48220680/188ae291_y.jpg) ### Hotel Puerto Pacifico Guayaquil Airport 10/10 Excellent "We're very close to the airport. A great place for a layover stay." [](https://expedia.ca/Guayaquil-Hotels-Hotel-Puerto-Pacifico.h48220680.Hotel-Information) ![Unipark by Oro Verde Hotels](https://images.trvl-media.com/lodging/1000000/10000/4400/4375/0c30e684_y.jpg) ### Unipark by Oro Verde Hotels 10/10 Excellent "Customer service, amenities, restaurant service. Professional team. Clean room, location. " [](https://expedia.ca/Guayaquil-Hotels-Unipark-By-Oro-Verde-Hotels.h4375.Hotel-Information) ## Frequently asked questions ### What is the best area to stay in Puerto Santa Ana? > For couples seeking a romantic escape, Tarqui provides a picturesque setting with its beautiful views and lively atmosphere. Sharing a meal at one of the many riverside eateries while watching the sunset can create unforgettable moments. The area's welcoming vibe and friendly locals only add to the experience, making it a great choice for couples looking to connect with each other and the local culture. > > > Families will also find Tarqui appealing, as it offers plenty of options for entertainment and relaxation. Nearby parks and playgrounds provide spaces for children to play, while parents can enjoy exploring local markets or indulging in delicious street food. The variety of family-friendly activities ensures that everyone can create lasting memories together. ### When is the best time to go to Puerto Santa Ana? > During the peak season from December to February, tourist activity is at its highest, with visitors flocking to enjoy the sunny weather and lively atmosphere. This is an ideal time for sightseeing, as you can easily explore the nearby attractions, from historic sites to contemporary art installations, all while basking in the pleasant, tropical climate. > > > For couples and families alike, the festive spirit in December creates a magical backdrop for making cherished memories. The Christmas lights and decorations transform the city, and there are often cultural events, markets, and concerts that add to the experience. You can take leisurely strolls along the waterfront or relax in one of the city's beautiful parks, soaking in the vibrant surroundings. > > > If you're looking for a more budget-friendly option, consider visiting in March. This month typically sees fewer tourists, allowing for a more tranquil experience while still enjoying the pleasant weather. You'll find that prices for accommodation and activities are often lower, providing excellent value without compromising on quality. ### Where can I find the best nightlife in Puerto Santa Ana? > The waterfront area is particularly lively, with a variety of bars and restaurants lining the banks of the Guayas River. Here, you can enjoy a vibrant atmosphere while sipping on cocktails or sampling local cuisine. The promenade is a popular spot for both locals and visitors, especially as the sun sets, creating a great backdrop for an evening out. > > > For those seeking a more energetic nightlife experience, the nearby Las Peñas district is well-known for its vibrant bars and live music venues. This historic area is often filled with both tourists and locals, making it a great place to mingle and enjoy the nightlife. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Puerto Santa Ana hotel booking with Expedia? ### How much is the nightly rate at a Puerto Santa Ana hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [Buijo Histórico Hotels ](https://www.expedia.ca/Buijo-Historico-Guayaquil-Hotels.0-n553248635976385128-0.Travel-Guide-Filter-Hotels) - [Chongón Hotels ](https://www.expedia.ca/Chongon-Guayaquil-Hotels.0-n553248635976386577-0.Travel-Guide-Filter-Hotels) - [Daular Hotels ](https://www.expedia.ca/Daular-Hotels.d553248635975864884.Travel-Guide-Hotels) - [Delia Hotels ](https://www.expedia.ca/Delia-Guayaquil-Hotels.0-n553248635975855772-0.Travel-Guide-Filter-Hotels) - [Guayas Hotels ](https://www.expedia.ca/Destinations-In-Guayas.d6239779.Hotel-Destinations) - [Lgbt Friendly Hotels in Downtown Guayaquil ](https://www.expedia.ca/Downtown-Guayaquil-Guayaquil-Hotels-LGBT-Friendly-Hotel.0-n6337572-0-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - 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