Title: 10 Best Hotels in Puerto Santa Ana, Guayaquil for 2025 | Expedia.ca [Puerto Santa Ana Travel Guide](https://expedia.ca/Guayaquil-Puerto-Santa-Ana.dx6338310)[Vacation Rentals in Guayaquil](https://expedia.ca/Guayaquil-Vacation-Rentals.d1414.Travel-Guide-VacationRentals)[Flights to Guayaquil](https://expedia.ca/Cheap-Flights-To-Guayaquil.d1414.Travel-Guide-Flights)[Things to do in Guayaquil](https://expedia.ca/Things-To-Do-In-Guayaquil.d1414.Travel-Guide-Activities)[Puerto Santa Ana Car Rentals](https://expedia.ca/Car-Rentals-In-Puerto-Santa-Ana.d6338310.Car-Rental-Guide)[Puerto Santa Ana Vacations](https://expedia.ca/Puerto-Santa-Ana.d6338310.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Hotels in Puerto Santa Ana, Guayaquil ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Puerto Santa Ana Apart hotel [](https://www.expedia.ca/Hotel-Search?destination=Puerto+Santa+Ana%2C+Guayaquil%2C+Guayas%2C+Ecuador®ionId=6338310&latLong=-2.177141%2C-79.876532&adults=2&startDate=2025-10-26&d1=2025-10-26&endDate=2025-10-28&d2=2025-10-28&lodging=APART_HOTEL) Spa [](https://www.expedia.ca/Hotel-Search?destination=Puerto+Santa+Ana%2C+Guayaquil%2C+Guayas%2C+Ecuador®ionId=6338310&latLong=-2.177141%2C-79.876532&adults=2&startDate=2025-10-26&d1=2025-10-26&endDate=2025-10-28&d2=2025-10-28&amenities=SPA_ON_SITE) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Puerto+Santa+Ana%2C+Guayaquil%2C+Guayas%2C+Ecuador®ionId=6338310&latLong=-2.177141%2C-79.876532&adults=2&startDate=2025-10-26&d1=2025-10-26&endDate=2025-10-28&d2=2025-10-28&lodging=APARTMENT) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Puerto+Santa+Ana%2C+Guayaquil%2C+Guayas%2C+Ecuador®ionId=6338310&latLong=-2.177141%2C-79.876532&adults=2&startDate=2025-10-26&d1=2025-10-26&endDate=2025-10-28&d2=2025-10-28&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=Puerto+Santa+Ana%2C+Guayaquil%2C+Guayas%2C+Ecuador®ionId=6338310&latLong=-2.177141%2C-79.876532&adults=2&startDate=2025-10-26&d1=2025-10-26&endDate=2025-10-28&d2=2025-10-28&amenities=POOL) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Puerto+Santa+Ana%2C+Guayaquil%2C+Guayas%2C+Ecuador®ionId=6338310&latLong=-2.177141%2C-79.876532&adults=2&startDate=2025-10-26&d1=2025-10-26&endDate=2025-10-28&d2=2025-10-28&amenities=HOT_TUB) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Puerto+Santa+Ana%2C+Guayaquil%2C+Guayas%2C+Ecuador®ionId=6338310&latLong=-2.177141%2C-79.876532&adults=2&startDate=2025-10-26&d1=2025-10-26&endDate=2025-10-28&d2=2025-10-28&amenities=PETS) Condo [](https://www.expedia.ca/Hotel-Search?destination=Puerto+Santa+Ana%2C+Guayaquil%2C+Guayas%2C+Ecuador®ionId=6338310&latLong=-2.177141%2C-79.876532&adults=2&startDate=2025-10-26&d1=2025-10-26&endDate=2025-10-28&d2=2025-10-28&lodging=CONDO) ## Check prices for these dates Tonight [Oct 12 - Oct 13](https://www.expedia.ca/Hotel-Search?regionId=6338310&startDate=2025-10-12&endDate=2025-10-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 13 - Oct 14](https://www.expedia.ca/Hotel-Search?regionId=6338310&startDate=2025-10-13&endDate=2025-10-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6338310&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6338310&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Puerto Santa Ana hotels and places to stay ![Presidential Suite, 1 King Bed, Jetted Tub, River View](https://images.trvl-media.com/lodging/7000000/6320000/6312500/6312483/79b2b000.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6320000/6312500/6312483/664af8f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/7000000/6320000/6312500/6312483/bf4ba68b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/7000000/6320000/6312500/6312483/69ea8661.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Guayaquil Puerto Santa Ana Puerto Santa Ana 9.2/10 Wonderful (1003) "Very nice hotel " CA $154 CA $173 total Nov 4 - Nov 5 [](https://www.expedia.ca/Guayaquil-Hotels-Wyndham-Guayaquil.h6312483.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/23000000/22660000/22652600/22652575/b3ec1eca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/23000000/22660000/22652600/22652575/e4fb9cbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Suite, 1 Bedroom](https://images.trvl-media.com/lodging/23000000/22660000/22652600/22652575/ea95563d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Suite, 1 Bedroom | Living room](https://images.trvl-media.com/lodging/23000000/22660000/22652600/22652575/ca36f487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### River View suites Puerto Santa Ana gye Puerto Santa Ana 8.4/10 Very good (38) "The staff were soo nice with me and my family !! I really enjoy my stay :)" CA $112 CA $114 total Oct 13 - Oct 14 [](https://www.expedia.ca/Guayaquil-Hotels-River-View-Suites-Puerto-Santa-Ana-Gye.h22652575.Hotel-Information) ![43-inch flat-screen TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/33000000/32050000/32048100/32048032/42319f76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/33000000/32050000/32048100/32048032/6c4f3ade.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor spa tub](https://images.trvl-media.com/lodging/33000000/32050000/32048100/32048032/04063cb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Apartment, 2 Bedrooms, Kitchen, Hill View (2 Bedrooms with 3 Beds) | Private kitchen](https://images.trvl-media.com/lodging/33000000/32050000/32048100/32048032/e88f5dd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury Suites Riverfront GYE Puerto Santa Ana 9.4/10 Exceptional (98) "Everything, it was incredible. I went with my family and they had a great time." [](https://www.expedia.ca/Guayaquil-Hotels-Luxury-Suites-Riverfront-GYE.h32048032.Hotel-Information) ![Rooftop bar, alfresco dining, open daily](https://images.trvl-media.com/lodging/2000000/1280000/1273600/1273513/a22c50d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1273600/1273513/996932e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1280000/1273600/1273513/3fe5a6c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/2000000/1280000/1273600/1273513/dd666b4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Garden Guayaquil Simón Bolívar, 2.8 km from Puerto Santa Ana 9.0/10 Wonderful (1008) "great staff easy access and parking, nice location " CA $118 CA $132 total Oct 19 - Oct 20 [](https://www.expedia.ca/Guayaquil-Hotels-Wyndham-Garden-Guayaquil.h1273513.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/6000000/5960000/5959100/5959068/15d3bf82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/6000000/5960000/5959100/5959068/d1da0946.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City view](https://images.trvl-media.com/lodging/6000000/5960000/5959100/5959068/985058ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/6000000/5960000/5959100/5959068/2607cc6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Guayaquil Airport by IHG 3.7 km from Puerto Santa Ana 9.4/10 Exceptional (1011) "This was an absolutely fabulous hotel and stay from our arrival and pick up to the staff at the hotel to the restaurant wonderful!" CA $128 CA $144 total Nov 3 - Nov 4 [](https://www.expedia.ca/Guayaquil-Hotels-Holiday-Inn-Guayaquil-Airport.h5959068.Hotel-Information) ![2 restaurants, breakfast, lunch, dinner served; Regional cuisine](https://images.trvl-media.com/lodging/1000000/560000/556000/556000/97a1664b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/560000/556000/556000/9272e9d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/560000/556000/556000/3a4230bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/560000/556000/556000/47299b68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sheraton Guayaquil Hotel Simón Bolívar, 2.9 km from Puerto Santa Ana 9.0/10 Wonderful (587) "The Front Desk Andrea was amazing and very kind. " CA $245 CA $273 total Oct 17 - Oct 18 [](https://www.expedia.ca/Guayaquil-Hotels-Sheraton-Guayaquil-Hotel.h556000.Hotel-Information) ![Children's activities](https://images.trvl-media.com/lodging/1000000/30000/23700/23682/104d895f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/23700/23682/5208cc59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/30000/23700/23682/14b51792.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Single Beds](https://images.trvl-media.com/lodging/1000000/30000/23700/23682/4267a74d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Oro Verde Guayaquil Downtown Guayaquil, 2.1 km from Puerto Santa Ana 9.4/10 Exceptional (1010) "Wonderful people,, great hotel . Very clean and comfortable stayed." CA $125 CA $141 total Oct 19 - Oct 20 [](https://www.expedia.ca/Guayaquil-Hotels-Oro-Verde-Guayaquil.h23682.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2750000/2745100/2745088/e22d8e0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking, City View](https://images.trvl-media.com/lodging/3000000/2750000/2745100/2745088/2bc408bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking, City View](https://images.trvl-media.com/lodging/3000000/2750000/2745100/2745088/d43fc9b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2750000/2745100/2745088/efe3ae94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Guayaquil Kennedy, 2.5 km from Puerto Santa Ana 8.8/10 Excellent (1005) "Great stay " CA $95 CA $107 total Oct 25 - Oct 26 [](https://www.expedia.ca/Guayaquil-Hotels-Courtyard-By-Marriott-Guayaquil.h2745088.Hotel-Information) ![Outdoor pool, open 8:00 AM to 9:00 PM, sun loungers](https://images.trvl-media.com/lodging/7000000/6760000/6751000/6750908/1d447ff4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee shop](https://images.trvl-media.com/lodging/7000000/6760000/6751000/6750908/6754254c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/7000000/6760000/6751000/6750908/940597ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6760000/6751000/6750908/4beadb23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Hotel Guayaquil, an Ascend Collection Hotel Rocafuerte, 2.2 km from Puerto Santa Ana 9.2/10 Wonderful (964) "Great place to Stay.!" CA $95 CA $107 total Nov 11 - Nov 12 [](https://www.expedia.ca/Guayaquil-Hotels-Grand-Hotel-Guayaquil.h6750908.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/4400/4375/0c30e684.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/4400/4375/3055cce5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/10000/4400/4375/c5093448.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/10000/4400/4375/bfa2a5dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Unipark by Oro Verde Hotels Rocafuerte, 2 km from Puerto Santa Ana 9.2/10 Wonderful (1002) "I enjoyed much my staying in this hotel." CA $97 CA $110 total Nov 4 - Nov 5 [](https://www.expedia.ca/Guayaquil-Hotels-Unipark-By-Oro-Verde-Hotels.h4375.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/20000000/19220000/19213600/19213532/d700f6bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/20000000/19220000/19213600/19213532/a654a5dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed, Non Smoking | View from room](https://images.trvl-media.com/lodging/20000000/19220000/19213600/19213532/e4300ade.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/20000000/19220000/19213600/19213532/a4fd92ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Hotel Guayaquil Kennedy, 2.9 km from Puerto Santa Ana 9.2/10 Wonderful (617) "Excellent staff." CA $113 CA $128 total Nov 1 - Nov 2 [](https://www.expedia.ca/Guayaquil-Hotels-Radisson-Guayaquil.h19213532.Hotel-Information) ![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/5000000/4440000/4436100/4436047/w3840h2557x0y3-5bee1b7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City view](https://images.trvl-media.com/lodging/5000000/4440000/4436100/4436047/cd0caacf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4440000/4436100/4436047/d18989f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4440000/4436100/4436047/4938f0cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TRYP by Wyndham Guayaquil Airport Simón Bolívar, 2.8 km from Puerto Santa Ana 9.0/10 Wonderful (1008) "Covenient, many options for dinning on premises. " CA $146 CA $165 total Nov 4 - Nov 5 [](https://www.expedia.ca/Guayaquil-Hotels-TRYP-By-Wyndham-Guayaquil.h4436047.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/20000000/19400000/19391900/19391858/2b961da2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/20000000/19400000/19391900/19391858/54545bba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Studio Suite | Terrace/patio](https://images.trvl-media.com/lodging/20000000/19400000/19391900/19391858/4c177673.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, 1 Queen Bed](https://images.trvl-media.com/lodging/20000000/19400000/19391900/19391858/798ca00b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Patrimonial by Greenfield Downtown Guayaquil, 1.4 km from Puerto Santa Ana 8.6/10 Excellent (131) "Excellent location and close to the airport." [](https://www.expedia.ca/Guayaquil-Hotels-Hotel-Patrimonial-By-Greenfield.h19391858.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/18000000/17340000/17331400/17331318/2a010657.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily continental breakfast (USD 5 per person)](https://images.trvl-media.com/lodging/18000000/17340000/17331400/17331318/c384b453.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/18000000/17340000/17331400/17331318/d29e2b28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/18000000/17340000/17331400/17331318/ef22dd38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DC Suites Aeropuerto Simón Bolívar, 3 km from Puerto Santa Ana 9.0/10 Wonderful (562) "Stayed for one night. Clean bathroom, easy to check in and very close to the airport. " [](https://www.expedia.ca/Guayaquil-Hotels-DC-Suites-Aeropuerto.h17331318.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/69100/69054/de7e624e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas](https://images.trvl-media.com/lodging/1000000/70000/69100/69054/8531ce07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/69100/69054/2aea4f00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/70000/69100/69054/58ce83fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Colon Guayaquil Kennedy, 3.2 km from Puerto Santa Ana 8.6/10 Excellent (778) "Well located. Safe. Pool and spa were excellent. " CA $136 CA $153 total Nov 3 - Nov 4 [](https://www.expedia.ca/Guayaquil-Hotels-Hilton-Colon-Guayaquil.h69054.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/94000000/93850000/93845100/93845075/22f53454.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (USD 11.99 per person)](https://images.trvl-media.com/lodging/94000000/93850000/93845100/93845075/d786af65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 2 Single Beds](https://images.trvl-media.com/lodging/94000000/93850000/93845100/93845075/bb3fa3c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/94000000/93850000/93845100/93845075/169cd786.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ibis Styles El Malecon Guayaquil Downtown Guayaquil, 1.6 km from Puerto Santa Ana 9.4/10 Exceptional (254) "Great location and great hotel " CA $84 CA $95 total Oct 17 - Oct 18 [](https://www.expedia.ca/Guayaquil-Hotels-Ibis-Styles-El-Malecon-Guayaquil.h93845075.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074261/0dae506e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074261/0845a13d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074261/bac7db86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily continental breakfast (USD 8 per person)](https://images.trvl-media.com/lodging/6000000/5080000/5074300/5074261/4565d086.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel GH Galeria Downtown Guayaquil, 2.1 km from Puerto Santa Ana 8.4/10 Very good (387) "Location " [](https://www.expedia.ca/Guayaquil-Hotels-Hotel-Galeria-Man-Ging.h5074261.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2220000/2211800/2211791/2f768d35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/3000000/2220000/2211800/2211791/78005c02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/3000000/2220000/2211800/2211791/6dcc9954.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/3000000/2220000/2211800/2211791/fbc24025.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Palace Guayaquil Rocafuerte, 1.9 km from Puerto Santa Ana 9.2/10 Wonderful (903) "Good place to stay " CA $88 CA $99 total Oct 17 - Oct 18 [](https://www.expedia.ca/Guayaquil-Hotels-Hotel-Palace-Guayaquil.h2211791.Hotel-Information) ![In-room safe, blackout drapes, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/110000000/109390000/109388300/109388206/42bd7516.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/110000000/109390000/109388300/109388206/w3840h2561x0y3-aa9d061b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/110000000/109390000/109388300/109388206/4fdf411d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![LCD TV, fireplace](https://images.trvl-media.com/lodging/110000000/109390000/109388300/109388206/w3837h2561x3y4-3184c225.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Doubletree By Hilton Guayaquil Rocafuerte, 1.8 km from Puerto Santa Ana 9.0/10 Wonderful (59) "The staff is amazing and the hotel is so beautiful." CA $96 CA $108 total Nov 2 - Nov 3 [](https://www.expedia.ca/Guayaquil-Hotels-Doubletree-By-Hilton-Guayaquil.h109388206.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/43000000/42410000/42407000/42406978/1bc3e847.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/43000000/42410000/42407000/42406978/8f1a8238.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/43000000/42410000/42407000/42406978/e7da0a3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/43000000/42410000/42407000/42406978/bfc806b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxva Hotel Boutique Urdesa, 3.5 km from Puerto Santa Ana 9.4/10 Exceptional (166) "Breakfast was ok and the staff is wonderful!" CA $89 CA $89 total Oct 26 - Oct 27 [](https://www.expedia.ca/Guayaquil-Hotels-Luxva-Hotel-Boutique.h42406978.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-26&endDate=2025-10-27®ionId=6338310&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FPuerto-Santa-Ana-Guayaquil-Hotels.0-n6338310-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FPuerto-Santa-Ana-Guayaquil-Hotels.0-n6338310-0.Travel-Guide-Filter-Hotels) ## Where to stay in Puerto Santa Ana Find the best Puerto Santa Ana areas and neighborhoods for the activities you enjoy most. [Learn more about Puerto Santa Ana](https://www.expedia.ca/Guayaquil-Puerto-Santa-Ana.dx6338310) - Downtown Guayaquil - Ecuador - Kennedy - Urdesa - Simón Bolívar [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=6337572) ![Downtown Guayaquil map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:jfkLr%7BsfNws%40cOiEsJhA%7Bd%40vAcO%7EAoHqCi%40%7CMwf%40tWlJ%7Ch%40tO_YdgB&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=efYuk0Ril1wmcsuwYNvCseyS7mU=) ### Downtown Guayaquil Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Central Market and Sports Federation of Guayas while you're in town. [See properties](https://www.expedia.ca/Hotel-Search?regionId=6337572) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976397513) ![Ecuador map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7E%60xLhvrfNgL%7DB%60BeFt%40BnAbAh%40ITPS%60%40pB%60BZYl%40Rg%40%5C%3FvB&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=ITAe6nXctcoLe9r_9tpkYiy1Tjw=) ### Ecuador Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976397513) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248633981744623) ![Kennedy map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:d%7CbLxnufNu%40YkJUz%40oGdLwWrh%40kf%40fE%7BBjHaBhpAoBv_%40t%40bWhAuHp%5BjZaJxEfNQfDqCpAcNdL_RfH_FxFwSkE%7Dc%40aEiFkA%7BKo%40kYnI%7DUd%40yKbBmHBoB%60BmAN%7DAkAa%40_IeAiAqBU_A%7E%40c%40%60EwAbD%3F%7EFuCv%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=XWwvskPj7fazk3NWYmm490jAt1Q=) ### Kennedy Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or Policentro while you're exploring the area. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248633981744623) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248633981744847) ![Urdesa map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7CcfLntwfNeTaRaHtMyHbAeB%7DD_BfBiCgPii%40dBg%5CiKbDad%40%7EMb%40rDsDfCoMtHfJ%7CE%7DAlEX%7EI_CdTY%7EImAjWiG%60%5EhDvg%40zJp%40nEk%40%60IeGlUmMxAkFbI_NxDEzH_ELkOmA%7DA%7EI&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=SIVSialjYPTUNX-z_yOYk5Am1Ro=) ### Urdesa Urdesa is well-liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to San Marino Mall or Policentro. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248633981744847) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976384862) ![Simón Bolívar map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%60%7BcLjqsfNaO%7BFsHgFdBqEsDm%5EYW%3FaA%5COrHiAjFKnDXfF%7EAxRtIhf%40zVc%5El%40sF%7E%40_HzCiD%7EDk%40HmEbE&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=qpnNaBPGUClPrWkhGP6-aHRquqw=) ### Simón Bolívar If you're spending some time in Simón Bolívar, Mall del Sol Shopping Center and Plaza del Sol are top sights worth seeing. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976384862) ## Top Puerto Santa Ana Hotel Reviews ![Hilton Colon Guayaquil](//images.trvl-media.com/lodging/1000000/70000/69100/69054/de7e624e_y.jpg) ### Hilton Colon Guayaquil 10/10 Excellent "Clean room " [](https://expedia.ca/Guayaquil-Hotels-Hilton-Colon-Guayaquil.h69054.Hotel-Information) ![Grand Hotel Guayaquil, an Ascend Collection Hotel](//images.trvl-media.com/lodging/7000000/6760000/6751000/6750908/1d447ff4_y.jpg) ### Grand Hotel Guayaquil, an Ascend Collection Hotel 10/10 Excellent "I love it " [](https://expedia.ca/Guayaquil-Hotels-Grand-Hotel-Guayaquil.h6750908.Hotel-Information) ![Unipark by Oro Verde Hotels](//images.trvl-media.com/lodging/1000000/10000/4400/4375/0c30e684_y.jpg) ### Unipark by Oro Verde Hotels 10/10 Excellent "Excellent" [](https://expedia.ca/Guayaquil-Hotels-Unipark-By-Oro-Verde-Hotels.h4375.Hotel-Information) ![Holiday Inn Guayaquil Airport by IHG](//images.trvl-media.com/lodging/6000000/5960000/5959100/5959068/15d3bf82_y.jpg) ### Holiday Inn Guayaquil Airport by IHG 10/10 Excellent "Clean room, good food for breakfast and friendly staff " [](https://expedia.ca/Guayaquil-Hotels-Holiday-Inn-Guayaquil-Airport.h5959068.Hotel-Information) ![Sheraton Guayaquil Hotel](//images.trvl-media.com/lodging/1000000/560000/556000/556000/97a1664b_y.jpg) ### Sheraton Guayaquil Hotel 10/10 Excellent "The Front Desk Andrea was amazing and very kind. " [](https://expedia.ca/Guayaquil-Hotels-Sheraton-Guayaquil-Hotel.h556000.Hotel-Information) ![TRYP by Wyndham Guayaquil Airport](//images.trvl-media.com/lodging/5000000/4440000/4436100/4436047/a69cdc33_y.jpg) ### TRYP by Wyndham Guayaquil Airport 10/10 Excellent "The hotel is clean, spotless, recommended." [](https://expedia.ca/Guayaquil-Hotels-TRYP-By-Wyndham-Guayaquil.h4436047.Hotel-Information) ![Oro Verde Guayaquil](//images.trvl-media.com/lodging/1000000/30000/23700/23682/104d895f_y.jpg) ### Oro Verde Guayaquil 10/10 Excellent "just like it, like the breakfast, staff and the rooms and other facilities." [](https://expedia.ca/Guayaquil-Hotels-Oro-Verde-Guayaquil.h23682.Hotel-Information) ![Radisson Hotel Guayaquil](//images.trvl-media.com/lodging/20000000/19220000/19213600/19213532/d700f6bc_y.jpg) ### Radisson Hotel Guayaquil 10/10 Excellent "The best" [](https://expedia.ca/Guayaquil-Hotels-Radisson-Guayaquil.h19213532.Hotel-Information) ![Wyndham Guayaquil Puerto Santa Ana](//images.trvl-media.com/lodging/7000000/6320000/6312500/6312483/79b2b000_y.jpg) ### Wyndham Guayaquil Puerto Santa Ana 10/10 Excellent "Excelente hotel, valió cada centavo" [](https://expedia.ca/Guayaquil-Hotels-Wyndham-Guayaquil.h6312483.Hotel-Information) ## Frequently asked questions ### What is the best area to stay in Puerto Santa Ana? > Tarqui is the best area to stay in Puerto Santa Ana for travellers looking to immerse themselves in the vibrant culture of Ecuador. This lively neighbourhood is a hub of activity, offering a blend of modern amenities and local charm. With its proximity to the scenic Guayas River, visitors can enjoy leisurely strolls along the waterfront, as well as access to delightful restaurants and cafes that showcase the region's culinary delights. > > > > For couples seeking a romantic escape, Tarqui provides a picturesque setting with its beautiful views and lively atmosphere. Sharing a meal at one of the many riverside eateries while watching the sunset can create unforgettable moments. The area's welcoming vibe and friendly locals only add to the experience, making it a great choice for couples looking to connect with each other and the local culture. > > > > Families will also find Tarqui appealing, as it offers plenty of options for entertainment and relaxation. Nearby parks and playgrounds provide spaces for children to play, while parents can enjoy exploring local markets or indulging in delicious street food. The variety of family-friendly activities ensures that everyone can create lasting memories together. ### When is the best time to go to Puerto Santa Ana? > The most popular time to visit Puerto Santa Ana is December, as the city comes alive with festive celebrations and warm, welcoming temperatures averaging around 26°C. This period is great for those who enjoy outdoor activities, such as exploring the vibrant riverside promenades and indulging in local culinary delights at open-air cafes. > > > > During the peak season from December to February, tourist activity is at its highest, with visitors flocking to enjoy the sunny weather and lively atmosphere. This is an ideal time for sightseeing, as you can easily explore the nearby attractions, from historic sites to contemporary art installations, all while basking in the pleasant, tropical climate. > > > > For couples and families alike, the festive spirit in December creates a magical backdrop for making cherished memories. The Christmas lights and decorations transform the city, and there are often cultural events, markets, and concerts that add to the experience. You can take leisurely strolls along the waterfront or relax in one of the city's beautiful parks, soaking in the vibrant surroundings. > > > > If you're looking for a more budget-friendly option, consider visiting in March. This month typically sees fewer tourists, allowing for a more tranquil experience while still enjoying the pleasant weather. You'll find that prices for accommodation and activities are often lower, providing excellent value without compromising on quality. ### Where can I find the best nightlife in Puerto Santa Ana? > Puerto Santa Ana, a charming riverside neighbourhood in Guayas, Ecuador, offers a delightful blend of relaxation and nightlife. > > > > The waterfront area is particularly lively, with a variety of bars and restaurants lining the banks of the Guayas River. Here, you can enjoy a vibrant atmosphere while sipping on cocktails or sampling local cuisine. The promenade is a popular spot for both locals and visitors, especially as the sun sets, creating a great backdrop for an evening out. > > > > For those seeking a more energetic nightlife experience, the nearby Las Peñas district is well-known for its vibrant bars and live music venues. This historic area is often filled with both tourists and locals, making it a great place to mingle and enjoy the nightlife. ### Can I cancel my hotel reservation on Expedia? > You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Puerto Santa Ana. ### How can I save on a Puerto Santa Ana hotel booking with Expedia? > Before booking your Puerto Santa Ana hotel, remember to join Expedia's free travel rewards program. Just sign up and sign in to access our lowest Member Prices as well as members-only perks. You could also enjoy savings by bundling together your hotel and flights on Expedia. ### How much is the nightly rate at a Puerto Santa Ana hotel? > Prices for hotels in Puerto Santa Ana often vary, but you can find a great deal on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. 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Airport](https://expedia.ca/Jose-Joaquin-De-Olmedo-Intl-Airport-Hotels.0-aGYE-0.Travel-Guide-Filter-Hotels) ### Explore more hotels - [Unipark by Oro Verde Hotels](https://expedia.ca/Guayaquil-Hotels-Unipark-By-Oro-Verde-Hotels.h4375.Hotel-Information) - [Grand Hotel Guayaquil, an Ascend Collection Hotel](https://expedia.ca/Guayaquil-Hotels-Grand-Hotel-Guayaquil.h6750908.Hotel-Information) - [Ibis Styles El Malecon Guayaquil](https://expedia.ca/Guayaquil-Hotels-Ibis-Styles-El-Malecon-Guayaquil.h93845075.Hotel-Information) - [TRYP by Wyndham Guayaquil Airport](https://expedia.ca/Guayaquil-Hotels-TRYP-By-Wyndham-Guayaquil.h4436047.Hotel-Information) - [Hotel Puerto Pacifico Guayaquil Airport](https://expedia.ca/Guayaquil-Hotels-Hotel-Puerto-Pacifico.h48220680.Hotel-Information) - [Doubletree By Hilton Guayaquil](https://expedia.ca/Guayaquil-Hotels-Doubletree-By-Hilton-Guayaquil.h109388206.Hotel-Information) - [Radisson Hotel Guayaquil](https://expedia.ca/Guayaquil-Hotels-Radisson-Guayaquil.h19213532.Hotel-Information) - [DC Suites Aeropuerto](https://expedia.ca/Guayaquil-Hotels-DC-Suites-Aeropuerto.h17331318.Hotel-Information) - [Hotel Patrimonial by Greenfield](https://expedia.ca/Guayaquil-Hotels-Hotel-Patrimonial-By-Greenfield.h19391858.Hotel-Information) - [Hotel Palace Guayaquil](https://expedia.ca/Guayaquil-Hotels-Hotel-Palace-Guayaquil.h2211791.Hotel-Information) - [Hotel Ramada](https://expedia.ca/Guayaquil-Hotels-Hotel-Ramada.h17245.Hotel-Information) [See a list of all hotels in Guayaquil](https://expedia.ca/All-Guayaquil-Hotels.d1414.Travel-Guide-City-All-Hotels) ### Expedia's Latest Trends Hotels - [Hotels in Clearwater](https://expedia.ca/Clearwater-Hotels.d6033.Travel-Guide-Hotels) - [Hotels in Erickson](https://expedia.ca/Erickson-Hotels.d3000480575.Travel-Guide-Hotels) - [Pan Pacific Toronto](https://expedia.ca/Toronto-Hotels-Pan-Pacific-Toronto.h19145.Hotel-Information) - [ATH Airport Hotels](https://expedia.ca/Eleftherios-Venizelos-Airport-Hotels.0-aATH-0.Travel-Guide-Filter-Hotels) - [Econo Lodge & Suites Saint John](https://expedia.ca/Saint-John-Hotels-Econo-Lodge-Suites-Saint-John.h475279.Hotel-Information) - [Hotel Indigo Napa Valley by IHG](https://expedia.ca/Napa-Hotels-Hotel-Indigo-Napa-Valley.h10942.Hotel-Information) - [Hotels in Niagara Falls](https://expedia.ca/Niagara-Falls-Hotels.d6023515.Travel-Guide-Hotels) Flights - [Flights to Sweden](https://expedia.ca/Destinations-In-Sweden.d173.Flight-Destinations) - [Cheap Flights from Toronto (YYZ) to Bakersfield (BFL)](https://expedia.ca/lp/flights/yyz/bfl/toronto-to-bakersfield) - [Cheap Flights from Vancouver (YVR) to Culiacan (CUL)](https://expedia.ca/lp/flights/yvr/cul/vancouver-to-culiacan) - [Cheap Flights from Toronto (YYZ) to London (LHR)](https://expedia.ca/lp/flights/yyz/lhr/toronto-to-london) - [Cheap Flights from Buffalo (BUF) to Baton Rouge (BTR)](https://expedia.ca/lp/flights/buf/btr/buffalo-to-baton-rouge) - [Cheap Flights from Ottawa (YOW) to Nantucket (ACK)](https://expedia.ca/lp/flights/yow/ack/ottawa-to-nantucket) - [Cheap Flights from Montreal (YUL) to David (DAV)](https://expedia.ca/lp/flights/yul/dav/montreal-to-david) - [Cheap Flights from Belgrade (BEG) to Toronto (YYZ)](https://expedia.ca/lp/flights/beg/yyz/belgrade-to-toronto) - [Flights to Canada](https://expedia.ca/Destinations-In-Canada.d31.Flight-Destinations) - [Cheap Flights from Toronto (YYZ) to Valencia (VLC)](https://expedia.ca/lp/flights/yyz/vlc/toronto-to-valencia) - [Corsair](https://expedia.ca/Corsair-Flights.cSS.Travel-Guide-Airlines) - [Cheap Flights from Delhi (DEL) to Toronto (YYZ)](https://expedia.ca/lp/flights/del/yyz/delhi-to-toronto) - [Cheap Flights from Kitchener (YKF) to Lethbridge (YQL)](https://expedia.ca/lp/flights/ykf/yql/kitchener-to-lethbridge) Cars - [Enterprise Car Rentals In Vancouver](https://expedia.ca/Enterprise-Car-Rentals-In-Vancouver.d178315-c15.Car-Rental-Guide-Suppliers) - [Alamo Rent A Car Car Rentals In Los Angeles Intl](https://expedia.ca/Alamo-Rent-A-Car-Car-Rentals-In-Los-Angeles-Intl.d5783884-c6.Car-Rental-Guide-Suppliers) - [Car rental Granadilla de Abona Airport (TFS)](https://expedia.ca/Car-Rentals-In-Tenerife-South.d5457492.Car-Rental-Guide) - [Car rentals in Calgary](https://expedia.ca/Car-Rentals-In-Calgary.d178245.Car-Rental-Guide) Activities - [Things to do in Winnipeg](https://expedia.ca/Things-To-Do-In-Winnipeg.d6141041.Travel-Guide-Activities) - [Things to do in Kamloops](https://expedia.ca/Things-To-Do-In-Kamloops.d3979.Travel-Guide-Activities) - [Things to do in Belize](https://expedia.ca/Things-To-Do-In-Belize.d18.Travel-Guide-Activities) Packages - [Parkwood Estate](https://expedia.ca/Parkwood-Estate-ONeill.d631603965420437504.Vacation-Attraction) - [Zabriskie Point](https://expedia.ca/Zabriskie-Point-Death-Valley.d553248621532641733.Vacation-Attraction) General - [Visit British Columbia](https://expedia.ca/British-Columbia.dx11117)