Title: 10 Best Hotels in Puerto Santa Ana, Guayaquil for 2026 | Expedia.ca

[Puerto Santa Ana Travel Guide](https://expedia.ca/Guayaquil-Puerto-Santa-Ana.dx6338310)[Vacation Rentals in Guayaquil](https://expedia.ca/Guayaquil-Vacation-Rentals.d1414.Travel-Guide-VacationRentals)[Flights to Guayaquil](https://expedia.ca/Cheap-Flights-To-Guayaquil.d1414.Travel-Guide-Flights)[Things to do in Guayaquil](https://expedia.ca/Things-To-Do-In-Guayaquil.d1414.Travel-Guide-Activities)[Puerto Santa Ana Car Rentals](https://expedia.ca/Car-Rentals-In-Puerto-Santa-Ana.d6338310.Car-Rental-Guide)[Puerto Santa Ana Vacations](https://expedia.ca/Puerto-Santa-Ana.d6338310.Destination-Travel-Guides)

![Vista panorámica de las favelas de cerro santa ana, guayaquil, ecuador](https://images.trvl-media.com/place/6338310/7d2e991e-9428-4fdb-b585-549f29a51fa9.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Hotels in Puerto Santa Ana, Guayaquil 

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## Go beyond your typical stay in Puerto Santa Ana

Spa

[](https://www.expedia.ca/Hotel-Search?destination=Puerto+Santa+Ana%2C+Guayaquil%2C+Guayas%2C+Ecuador&regionId=6338310&latLong=-2.177141%2C-79.876532&adults=2&startDate=2025-12-26&d1=2025-12-26&endDate=2025-12-28&d2=2025-12-28&amenities=SPA_ON_SITE)

Family friendly

[](https://www.expedia.ca/Hotel-Search?destination=Puerto+Santa+Ana%2C+Guayaquil%2C+Guayas%2C+Ecuador&regionId=6338310&latLong=-2.177141%2C-79.876532&adults=2&startDate=2025-12-26&d1=2025-12-26&endDate=2025-12-28&d2=2025-12-28&travelerType=family_friendly)

Apart hotel

[](https://www.expedia.ca/Hotel-Search?destination=Puerto+Santa+Ana%2C+Guayaquil%2C+Guayas%2C+Ecuador&regionId=6338310&latLong=-2.177141%2C-79.876532&adults=2&startDate=2025-12-26&d1=2025-12-26&endDate=2025-12-28&d2=2025-12-28&lodging=APART_HOTEL)

Pool

[](https://www.expedia.ca/Hotel-Search?destination=Puerto+Santa+Ana%2C+Guayaquil%2C+Guayas%2C+Ecuador&regionId=6338310&latLong=-2.177141%2C-79.876532&adults=2&startDate=2025-12-26&d1=2025-12-26&endDate=2025-12-28&d2=2025-12-28&amenities=POOL)

Apart­ment

[](https://www.expedia.ca/Hotel-Search?destination=Puerto+Santa+Ana%2C+Guayaquil%2C+Guayas%2C+Ecuador&regionId=6338310&latLong=-2.177141%2C-79.876532&adults=2&startDate=2025-12-26&d1=2025-12-26&endDate=2025-12-28&d2=2025-12-28&lodging=APARTMENT)

Hot tub

[](https://www.expedia.ca/Hotel-Search?destination=Puerto+Santa+Ana%2C+Guayaquil%2C+Guayas%2C+Ecuador&regionId=6338310&latLong=-2.177141%2C-79.876532&adults=2&startDate=2025-12-26&d1=2025-12-26&endDate=2025-12-28&d2=2025-12-28&amenities=HOT_TUB)

Pet friendly

[](https://www.expedia.ca/Hotel-Search?destination=Puerto+Santa+Ana%2C+Guayaquil%2C+Guayas%2C+Ecuador&regionId=6338310&latLong=-2.177141%2C-79.876532&adults=2&startDate=2025-12-26&d1=2025-12-26&endDate=2025-12-28&d2=2025-12-28&amenities=PETS)

Condo

[](https://www.expedia.ca/Hotel-Search?destination=Puerto+Santa+Ana%2C+Guayaquil%2C+Guayas%2C+Ecuador&regionId=6338310&latLong=-2.177141%2C-79.876532&adults=2&startDate=2025-12-26&d1=2025-12-26&endDate=2025-12-28&d2=2025-12-28&lodging=CONDO)

## Check prices for these dates

Tonight

[Dec 12 - Dec 13](https://www.expedia.ca/Hotel-Search?regionId=6338310&startDate=2025-12-12&endDate=2025-12-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Dec 13 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6338310&startDate=2025-12-13&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6338310&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6338310&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Our top choices for Puerto Santa Ana hotels

![Outdoor pool](https://images.trvl-media.com/lodging/23000000/22660000/22652600/22652575/b3ec1eca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Suite, 1 Bedroom | Living room](https://images.trvl-media.com/lodging/23000000/22660000/22652600/22652575/ca36f487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/23000000/22660000/22652600/22652575/1ace7a1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Suite, 1 Bedroom](https://images.trvl-media.com/lodging/23000000/22660000/22652600/22652575/ea95563d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### River View suites Puerto Santa Ana gye

[](https://www.expedia.ca/Guayaquil-Hotels-River-View-Suites-Puerto-Santa-Ana-Gye.h22652575.Hotel-Information)

Puerto Santa Ana

8.6/10

Excellent

(42)

"The staff were soo nice with me and my family !! I really enjoy my stay :)"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Maria

CA $99

CA $101 total

Dec 17 - Dec 18

[](https://www.expedia.ca/Guayaquil-Hotels-River-View-Suites-Puerto-Santa-Ana-Gye.h22652575.Hotel-Information)

![43-inch flat-screen TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/33000000/32050000/32048100/32048032/42319f76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Apartment, 2 Bedrooms, Kitchen, Hill View (2 Bedrooms with 3 Beds) | Living area](https://images.trvl-media.com/lodging/33000000/32050000/32048100/32048032/332f0478.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/33000000/32050000/32048100/32048032/6c4f3ade.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Apartment, 2 Bedrooms, Kitchen, Hill View (2 Bedrooms with 3 Beds) | Private kitchen](https://images.trvl-media.com/lodging/33000000/32050000/32048100/32048032/e88f5dd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Luxury Suites Riverfront GYE

[](https://www.expedia.ca/Guayaquil-Hotels-Luxury-Suites-Riverfront-GYE.h32048032.Hotel-Information)

Puerto Santa Ana

9.4/10

Exceptional

(100)

"The apartment was in a great location and very clean and well maintained."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rolando

CA $152

CA $154 total

Dec 22 - Dec 23

[](https://www.expedia.ca/Guayaquil-Hotels-Luxury-Suites-Riverfront-GYE.h32048032.Hotel-Information)

![Presidential Suite, 1 King Bed, Jetted Tub, River View](https://images.trvl-media.com/lodging/7000000/6320000/6312500/6312483/79b2b000.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Presidential Suite, 1 King Bed, Jetted Tub, River View](https://images.trvl-media.com/lodging/7000000/6320000/6312500/6312483/8315afb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/7000000/6320000/6312500/6312483/69ea8661.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/7000000/6320000/6312500/6312483/664af8f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Wyndham Guayaquil Puerto Santa Ana

[](https://www.expedia.ca/Guayaquil-Hotels-Wyndham-Guayaquil.h6312483.Hotel-Information)

Puerto Santa Ana

9.2/10

Wonderful

(1000)

"The hotel and service were great!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rolando

CA $152

CA $171 total

Dec 13 - Dec 14

[](https://www.expedia.ca/Guayaquil-Hotels-Wyndham-Guayaquil.h6312483.Hotel-Information)

![Living area](https://images.trvl-media.com/lodging/122000000/121980000/121970100/121970069/ac2e3f76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic Double Room, Courtyard View](https://images.trvl-media.com/lodging/122000000/121980000/121970100/121970069/9abd4c58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/122000000/121980000/121970100/121970069/e319e850.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Oven, stovetop, cookware/dishes/utensils](https://images.trvl-media.com/lodging/122000000/121980000/121970100/121970069/3290d5a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pachamac House

[](https://www.expedia.ca/Guayaquil-Hotels-Pachamac-House.h121970069.Hotel-Information)

2.9 km from Puerto Santa Ana

CA $27

CA $27 total

Dec 14 - Dec 15

[](https://www.expedia.ca/Guayaquil-Hotels-Pachamac-House.h121970069.Hotel-Information)

![In-room safe, free WiFi](https://images.trvl-media.com/lodging/100000000/99980000/99979800/99979748/9195a1a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, free WiFi](https://images.trvl-media.com/lodging/100000000/99980000/99979800/99979748/771f37a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Economy Double Room](https://images.trvl-media.com/lodging/100000000/99980000/99979800/99979748/96f63d6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, free WiFi](https://images.trvl-media.com/lodging/100000000/99980000/99979800/99979748/8055c429.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Malecon Guesthouse

[](https://www.expedia.ca/Guayaquil-Hotels-Malecon-Guesthouse.h99979748.Hotel-Information)

1 km from Puerto Santa Ana

CA $19

CA $34 total

Dec 14 - Dec 15

[](https://www.expedia.ca/Guayaquil-Hotels-Malecon-Guesthouse.h99979748.Hotel-Information)

![Habitación cuádruple ejecutiva, dormitorio mixto, baño compartido, vistas a la ciudad (1) | View from room](https://images.trvl-media.com/lodging/30000000/29930000/29925900/29925872/a609cc8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/30000000/29930000/29925900/29925872/0c0314f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Staircase](https://images.trvl-media.com/lodging/30000000/29930000/29925900/29925872/bc7d9393.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/30000000/29930000/29925900/29925872/80b7df2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Villa Celeste - VC

[](https://www.expedia.ca/Guayaquil-Hotels-Villa-Celeste-VC.h29925872.Hotel-Information)

4.9 km from Puerto Santa Ana

7.2/10

Good

(12)

"It is a good place, they respect your privacity and has a good communication with tourist places "

![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg)

Moises Reque

CA $22

CA $22 total

Dec 13 - Dec 14

[](https://www.expedia.ca/Guayaquil-Hotels-Villa-Celeste-VC.h29925872.Hotel-Information)

![Premium bedding, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/19000000/18730000/18723200/18723150/004860f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/19000000/18730000/18723200/18723150/08d5e5eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily full breakfast](https://images.trvl-media.com/lodging/19000000/18730000/18723200/18723150/1d60ec28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/19000000/18730000/18723200/18723150/53356324.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel La Ria Durán

[](https://www.expedia.ca/Guayaquil-Hotels-Hotel-La-Ria-Duran.h18723150.Hotel-Information)

3.3 km from Puerto Santa Ana

7.2/10

Good

(19)

"Muy buena experiencia"

![Ecuador](https://a.travel-assets.com/egds/marks/flags/ec.svg)

HERNAN

CA $66

CA $66 total

Dec 13 - Dec 14

[](https://www.expedia.ca/Guayaquil-Hotels-Hotel-La-Ria-Duran.h18723150.Hotel-Information)

![Restaurant](https://images.trvl-media.com/lodging/114000000/113770000/113765400/113765303/e7a717d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/114000000/113770000/113765400/113765303/28f7fd75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/114000000/113770000/113765400/113765303/4b92a37e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/114000000/113770000/113765400/113765303/02d3f2d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Río Guayas by Art Hotels Ecuador 

[](https://www.expedia.ca/Guayaquil-Hotels-Hotel-Rio-Guayas.h113765303.Hotel-Information)

Las Peñas, 0.6 km from Puerto Santa Ana

10/10

Exceptional

(2)

"The staff was very friendly and helpful. The hotel is new and modern, it is a good place to relax and work. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Richard

CA $354

CA $395 total

Dec 19 - Dec 20

[](https://www.expedia.ca/Guayaquil-Hotels-Hotel-Rio-Guayas.h113765303.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/102000000/101760000/101750500/101750483/dc579336.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Ecotours](https://images.trvl-media.com/lodging/102000000/101760000/101750500/101750483/ca8ca9e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/102000000/101760000/101750500/101750483/47dac461.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![45-inch Smart TV with digital channels, Netflix, streaming services](https://images.trvl-media.com/lodging/102000000/101760000/101750500/101750483/95188a3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fortune Hotel 

[](https://www.expedia.ca/Guayaquil-Hotels-Fortune-Hotel.h101750483.Hotel-Information)

1 km from Puerto Santa Ana

8.0/10

Very good

(7)

"Very bad Hotel. Not using Expedia again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Bryan

CA $60

CA $62 total

Jan 1 - Jan 2, 2026

[](https://www.expedia.ca/Guayaquil-Hotels-Fortune-Hotel.h101750483.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/46000000/45180000/45173500/45173420/b6d5e5bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Double Room, 1 King Bed, Private Bathroom](https://images.trvl-media.com/lodging/46000000/45180000/45173500/45173420/496d3338.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/46000000/45180000/45173500/45173420/53f362a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/46000000/45180000/45173500/45173420/eeaef3a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hostal Macaw

[](https://www.expedia.ca/Guayaquil-Hotels-Hostal-Macaw.h45173420.Hotel-Information)

Kennedy, 2.9 km from Puerto Santa Ana

10/10

Exceptional

(9)

"Wonderful hosts and felt like home "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tina

CA $96

CA $98 total

Dec 13 - Dec 14

[](https://www.expedia.ca/Guayaquil-Hotels-Hostal-Macaw.h45173420.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/84000000/83920000/83919600/83919535/6a3f2cec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/84000000/83920000/83919600/83919535/9f3eb4dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Twin Room, 2 Double Beds | Room amenity](https://images.trvl-media.com/lodging/84000000/83920000/83919600/83919535/84846b7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/84000000/83920000/83919600/83919535/764976b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hostal California Inn

[](https://www.expedia.ca/Guayaquil-Hotels-Hostal-California-Inn.h83919535.Hotel-Information)

1.5 km from Puerto Santa Ana

8.6/10

Excellent

(8)

"Me encantó, es muy cómoda, la habitación super amplia y limpia Si duda volveré "

![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg)

Anita

[](https://www.expedia.ca/Guayaquil-Hotels-Hostal-California-Inn.h83919535.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/18000000/17170000/17163300/17163266/afc4e9f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Signature Room, 1 King Bed, Garden View | Garden view](https://images.trvl-media.com/lodging/18000000/17170000/17163300/17163266/d5606279.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business centre](https://images.trvl-media.com/lodging/18000000/17170000/17163300/17163266/e05bbd94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/18000000/17170000/17163300/17163266/572c82cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel del Parque

[](https://www.expedia.ca/Guayaquil-Hotels-Hotel-Del-Parque.h17163266.Hotel-Information)

3.6 km from Puerto Santa Ana

9.8/10

Exceptional

(106)

"I love"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Maria

CA $591

CA $650 total

Dec 29 - Dec 30

[](https://www.expedia.ca/Guayaquil-Hotels-Hotel-Del-Parque.h17163266.Hotel-Information)

![Executive Suite, Kitchenette, City View | Private kitchen](https://images.trvl-media.com/lodging/105000000/104820000/104814100/104814029/74e7651f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room | Bathroom](https://images.trvl-media.com/lodging/105000000/104820000/104814100/104814029/ed09222f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Suite, Kitchenette, City View | Private kitchen](https://images.trvl-media.com/lodging/105000000/104820000/104814100/104814029/51248e19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Suite, Kitchenette, City View](https://images.trvl-media.com/lodging/105000000/104820000/104814100/104814029/47c22f24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Suitesecu Rentals Guayaquil

[](https://www.expedia.ca/Guayaquil-Hotels-Suitesecu-Guayaquil.h104814029.Hotel-Information)

Simón Bolívar, 3.2 km from Puerto Santa Ana

9.2/10

Wonderful

(7)

"You can walk to the airport."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Digna

CA $37

CA $46 total

Dec 22 - Dec 23

[](https://www.expedia.ca/Guayaquil-Hotels-Suitesecu-Guayaquil.h104814029.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/102000000/101150000/101143800/101143744/0cf5013f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/102000000/101150000/101143800/101143744/5dd09d73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/102000000/101150000/101143800/101143744/c3cfefde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Honeymoon Double Room](https://images.trvl-media.com/lodging/102000000/101150000/101143800/101143744/803a66d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### HOTEL PERLA CENTRAL MALECON

[](https://www.expedia.ca/Guayaquil-Hotels-HOTEL-PERLA-CENTRAL-MALECON.h101143744.Hotel-Information)

Downtown Guayaquil, 1.3 km from Puerto Santa Ana

7.6/10

Good

(18)

"Balcony view was very cool "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Julio

CA $39

CA $39 total

Dec 17 - Dec 18

[](https://www.expedia.ca/Guayaquil-Hotels-HOTEL-PERLA-CENTRAL-MALECON.h101143744.Hotel-Information)

![Lobby lounge](https://images.trvl-media.com/lodging/13000000/12080000/12070900/12070859/536a4fbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/13000000/12080000/12070900/12070859/f2386846.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/13000000/12080000/12070900/12070859/d9e37e94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Double Room](https://images.trvl-media.com/lodging/13000000/12080000/12070900/12070859/5d981eec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Mansión del Río

[](https://www.expedia.ca/Guayaquil-Hotels-Mansion-Del-Rio.h12070859.Hotel-Information)

Las Peñas, 0.6 km from Puerto Santa Ana

8.8/10

Excellent

(133)

"Older but beautiful building. Very nice rooms. Good location. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Matthew

CA $82

CA $91 total

Dec 14 - Dec 15

[](https://www.expedia.ca/Guayaquil-Hotels-Mansion-Del-Rio.h12070859.Hotel-Information)

![Front of property - evening/night](https://images.trvl-media.com/lodging/4000000/3090000/3081200/3081144/fee31467.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Quadruple Room](https://images.trvl-media.com/lodging/4000000/3090000/3081200/3081144/fc65cf90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/4000000/3090000/3081200/3081144/2605ae41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast and lunch served](https://images.trvl-media.com/lodging/4000000/3090000/3081200/3081144/cf3efa1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Guayaquil Hostel Suites Madrid

[](https://www.expedia.ca/Guayaquil-Hotels-Guayaquil-Hostel-Suites-Madrid.h3081144.Hotel-Information)

1.7 km from Puerto Santa Ana

7.2/10

Good

(32)

"noisy and dark but friendly staff central location"

![Germany](https://a.travel-assets.com/egds/marks/flags/de.svg)

Anonymous traveller

CA $51

CA $52 total

Dec 13 - Dec 14

[](https://www.expedia.ca/Guayaquil-Hotels-Guayaquil-Hostel-Suites-Madrid.h3081144.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/36000000/35800000/35793600/35793535/379c4268.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Double Room, 1 Double Bed](https://images.trvl-media.com/lodging/36000000/35800000/35793600/35793535/34bc6762.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/36000000/35800000/35793600/35793535/da2517f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Double Room, 1 Double Bed | Bathroom](https://images.trvl-media.com/lodging/36000000/35800000/35793600/35793535/0b7b0a53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Veranda

[](https://www.expedia.ca/Guayaquil-Hotels-Casa-Veranda.h35793535.Hotel-Information)

12.9 km from Puerto Santa Ana

[](https://www.expedia.ca/Guayaquil-Hotels-Casa-Veranda.h35793535.Hotel-Information)

![Basic Twin Room | Living area](https://images.trvl-media.com/lodging/115000000/114970000/114965400/114965387/efa83929.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Apartment, Kitchenette | Private kitchen](https://images.trvl-media.com/lodging/115000000/114970000/114965400/114965387/81f76e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Apartment, Kitchenette | Private kitchen](https://images.trvl-media.com/lodging/115000000/114970000/114965400/114965387/772ab89e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Apartment, Kitchenette](https://images.trvl-media.com/lodging/115000000/114970000/114965400/114965387/e8be61a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Guayacan Apart Hotel 

[](https://www.expedia.ca/Guayaquil-Hotels-Guayacan-Apart-Hotel.h114965387.Hotel-Information)

Downtown Guayaquil, 1.6 km from Puerto Santa Ana

CA $55

CA $55 total

Dec 13 - Dec 14

[](https://www.expedia.ca/Guayaquil-Hotels-Guayacan-Apart-Hotel.h114965387.Hotel-Information)

![Classic Apartment | Living area](https://images.trvl-media.com/lodging/104000000/103430000/103420200/103420124/e8d359c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![32-inch Smart TV with digital channels, first-run movies](https://images.trvl-media.com/lodging/104000000/103430000/103420200/103420124/a4a5b5c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic Apartment](https://images.trvl-media.com/lodging/104000000/103430000/103420200/103420124/71d2028c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![32-inch Smart TV with digital channels, first-run movies](https://images.trvl-media.com/lodging/104000000/103430000/103420200/103420124/1b5f7a98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Departamentos en la Garzota

[](https://www.expedia.ca/Guayaquil-Hotels-Departamentos-En-La-Garzota.h103420124.Hotel-Information)

Garzota, 4 km from Puerto Santa Ana

CA $40

CA $43 total

Jan 8 - Jan 9, 2026

[](https://www.expedia.ca/Guayaquil-Hotels-Departamentos-En-La-Garzota.h103420124.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/98000000/97050000/97047000/97046910/183a5dd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Gym](https://images.trvl-media.com/lodging/98000000/97050000/97047000/97046910/b3093940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Presidential Suite](https://images.trvl-media.com/lodging/98000000/97050000/97047000/97046910/5c29f022.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Suite](https://images.trvl-media.com/lodging/98000000/97050000/97047000/97046910/10202e14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Cityzen Guayaquil

[](https://www.expedia.ca/Guayaquil-Hotels-Hotel-Cityzen-Guayaquil.h97046910.Hotel-Information)

1.6 km from Puerto Santa Ana

9.0/10

Wonderful

(37)

"Was nice "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Joe

[](https://www.expedia.ca/Guayaquil-Hotels-Hotel-Cityzen-Guayaquil.h97046910.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-26&endDate=2025-12-27&regionId=6338310&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Where to stay in Puerto Santa Ana

Find the best Puerto Santa Ana areas and neighborhoods for the activities you enjoy most. [Learn more about Puerto Santa Ana](https://www.expedia.ca/Guayaquil-Puerto-Santa-Ana.dx6338310)

- Ecuador
- Downtown Guayaquil
- Urdesa
- Kennedy
- Garzota

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=553248635976397513)

![Ecuador map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7E%60xLhvrfNgL%7DB%60BeFt%40BnAbAh%40ITPS%60%40pB%60BZYl%40Rg%40%5C%3FvB&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=ITAe6nXctcoLe9r_9tpkYiy1Tjw=)

### Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur. 

[See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976397513)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=6337572)

![Downtown Guayaquil map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:jfkLr%7BsfNws%40cOiEsJhA%7Bd%40vAcO%7EAoHqCi%40%7CMwf%40tWlJ%7Ch%40tO_YdgB&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=efYuk0Ril1wmcsuwYNvCseyS7mU=)

### Downtown Guayaquil

Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like San Francisco Square and Central Market while you're in town. 

[See properties](https://www.expedia.ca/Hotel-Search?regionId=6337572)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=553248633981744847)

![Urdesa map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7CcfLntwfNeTaRaHtMyHbAeB%7DD_BfBiCgPii%40dBg%5CiKbDad%40%7EMb%40rDsDfCoMtHfJ%7CE%7DAlEX%7EI_CdTY%7EImAjWiG%60%5EhDvg%40zJp%40nEk%40%60IeGlUmMxAkFbI_NxDEzH_ELkOmA%7DA%7EI&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=SIVSialjYPTUNX-z_yOYk5Am1Ro=)

### Urdesa

Urdesa is well-liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to San Marino Mall or Alban Borja Commercial Center. 

[See properties](https://www.expedia.ca/Hotel-Search?regionId=553248633981744847)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=553248633981744623)

![Kennedy map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:d%7CbLxnufNu%40YkJUz%40oGdLwWrh%40kf%40fE%7BBjHaBhpAoBv_%40t%40bWhAuHp%5BjZaJxEfNQfDqCpAcNdL_RfH_FxFwSkE%7Dc%40aEiFkA%7BKo%40kYnI%7DUd%40yKbBmHBoB%60BmAN%7DAkAa%40_IeAiAqBU_A%7E%40c%40%60EwAbD%3F%7EFuCv%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=XWwvskPj7fazk3NWYmm490jAt1Q=)

### Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area. 

[See properties](https://www.expedia.ca/Hotel-Search?regionId=553248633981744623)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=553248633981707957)

![Garzota map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:vibLlntfNsp%40geBhGeFfF%7C%40%7Ee%40nQvFnAtHKlEnc%40cB%7EDbUhKiI%60Eod%40%7EX&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=06PGKKK6dkbS8hNUnTi_u0dnDlI=)

### Garzota

The restaurants and shopping are a few reasons travelers visit Garzota. Though there aren't many top sights in the neighborhood, you can visit Mall del Sol Shopping Center and Plaza del Sol, a few notable attractions nearby. 

[See properties](https://www.expedia.ca/Hotel-Search?regionId=553248633981707957)

## Top Puerto Santa Ana Hotel Reviews

![Holiday Inn Guayaquil Airport by IHG](https://images.trvl-media.com/lodging/6000000/5960000/5959100/5959068/15d3bf82_y.jpg)

### Holiday Inn Guayaquil Airport by IHG

10/10 Excellent

"I arrived at 12:15am and they had the shuttle I requested ready. I go upgraded to a suite which was very nice. "

[](https://expedia.ca/Guayaquil-Hotels-Holiday-Inn-Guayaquil-Airport.h5959068.Hotel-Information)

![Hilton Colon Guayaquil](https://images.trvl-media.com/lodging/1000000/70000/69100/69054/de7e624e_y.jpg)

### Hilton Colon Guayaquil

10/10 Excellent

"Great room"

[](https://expedia.ca/Guayaquil-Hotels-Hilton-Colon-Guayaquil.h69054.Hotel-Information)

![Sheraton Guayaquil Hotel](https://images.trvl-media.com/lodging/1000000/560000/556000/556000/97a1664b_y.jpg)

### Sheraton Guayaquil Hotel

10/10 Excellent

"Employees at the Sheraton were the best, and they made the stay better"

[](https://expedia.ca/Guayaquil-Hotels-Sheraton-Guayaquil-Hotel.h556000.Hotel-Information)

![Unipark by Oro Verde Hotels](https://images.trvl-media.com/lodging/1000000/10000/4400/4375/0c30e684_y.jpg)

### Unipark by Oro Verde Hotels

10/10 Excellent

"Everything "

[](https://expedia.ca/Guayaquil-Hotels-Unipark-By-Oro-Verde-Hotels.h4375.Hotel-Information)

![Wyndham Garden Guayaquil](https://images.trvl-media.com/lodging/2000000/1280000/1273600/1273513/a22c50d5_y.jpg)

### Wyndham Garden Guayaquil

10/10 Excellent

"Wonder "

[](https://expedia.ca/Guayaquil-Hotels-Wyndham-Garden-Guayaquil.h1273513.Hotel-Information)

![Courtyard by Marriott Guayaquil](https://images.trvl-media.com/lodging/3000000/2750000/2745100/2745088/e22d8e0e_y.jpg)

### Courtyard by Marriott Guayaquil

10/10 Excellent

"Excellent"

[](https://expedia.ca/Guayaquil-Hotels-Courtyard-By-Marriott-Guayaquil.h2745088.Hotel-Information)

![Wyndham Guayaquil Puerto Santa Ana](https://images.trvl-media.com/lodging/7000000/6320000/6312500/6312483/79b2b000_y.jpg)

### Wyndham Guayaquil Puerto Santa Ana

10/10 Excellent

"The hotel and service were great!"

[](https://expedia.ca/Guayaquil-Hotels-Wyndham-Guayaquil.h6312483.Hotel-Information)

![Oro Verde Guayaquil](https://images.trvl-media.com/lodging/1000000/30000/23700/23682/104d895f_y.jpg)

### Oro Verde Guayaquil

10/10 Excellent

"Excellent service, the staff are super helpful and friendly."

[](https://expedia.ca/Guayaquil-Hotels-Oro-Verde-Guayaquil.h23682.Hotel-Information)

![Radisson Hotel Guayaquil](https://images.trvl-media.com/lodging/20000000/19220000/19213600/19213532/d700f6bc_y.jpg)

### Radisson Hotel Guayaquil

10/10 Excellent

"Good service "

[](https://expedia.ca/Guayaquil-Hotels-Radisson-Guayaquil.h19213532.Hotel-Information)

## Frequently asked questions

### What is the best area to stay in Puerto Santa Ana?

> For couples seeking a romantic escape, Tarqui provides a picturesque setting with its beautiful views and lively atmosphere. Sharing a meal at one of the many riverside eateries while watching the sunset can create unforgettable moments. The area's welcoming vibe and friendly locals only add to the experience, making it a great choice for couples looking to connect with each other and the local culture.
> 
>   
> Families will also find Tarqui appealing, as it offers plenty of options for entertainment and relaxation. Nearby parks and playgrounds provide spaces for children to play, while parents can enjoy exploring local markets or indulging in delicious street food. The variety of family-friendly activities ensures that everyone can create lasting memories together.

### When is the best time to go to Puerto Santa Ana?

> During the peak season from December to February, tourist activity is at its highest, with visitors flocking to enjoy the sunny weather and lively atmosphere. This is an ideal time for sightseeing, as you can easily explore the nearby attractions, from historic sites to contemporary art installations, all while basking in the pleasant, tropical climate.
> 
>   
> For couples and families alike, the festive spirit in December creates a magical backdrop for making cherished memories. The Christmas lights and decorations transform the city, and there are often cultural events, markets, and concerts that add to the experience. You can take leisurely strolls along the waterfront or relax in one of the city's beautiful parks, soaking in the vibrant surroundings.
> 
>   
> If you're looking for a more budget-friendly option, consider visiting in March. This month typically sees fewer tourists, allowing for a more tranquil experience while still enjoying the pleasant weather. You'll find that prices for accommodation and activities are often lower, providing excellent value without compromising on quality.

### Where can I find the best nightlife in Puerto Santa Ana?

> The waterfront area is particularly lively, with a variety of bars and restaurants lining the banks of the Guayas River. Here, you can enjoy a vibrant atmosphere while sipping on cocktails or sampling local cuisine. The promenade is a popular spot for both locals and visitors, especially as the sun sets, creating a great backdrop for an evening out.
> 
>   
> For those seeking a more energetic nightlife experience, the nearby Las Peñas district is well-known for its vibrant bars and live music venues. This historic area is often filled with both tourists and locals, making it a great place to mingle and enjoy the nightlife.

### Can I cancel my hotel reservation on Expedia?

### How can I save on a Puerto Santa Ana hotel booking with Expedia?

### How much is the nightly rate at a Puerto Santa Ana hotel?

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- [Las Peñas Hotels ](https://www.expedia.ca/Las-Penas-Guayaquil-Hotels.0-n6160677-0.Travel-Guide-Filter-Hotels)
- [Hotels near Malecon 2000 ](https://www.expedia.ca/Malecon-2000-Hotels.0-l6112432-0.Travel-Guide-Filter-Hotels)
- [Hotels near Mall del Sol Shopping Center ](https://www.expedia.ca/Mall-Del-Sol-Shopping-Center-Hotels.0-l6160670-0.Travel-Guide-Filter-Hotels)
- [Milagro Hotels ](https://www.expedia.ca/Milagro-Hotels.d6340360.Travel-Guide-Hotels)
- [Miraflores Hotels ](https://www.expedia.ca/Miraflores-Guayaquil-Hotels.0-n553248635976395346-0.Travel-Guide-Filter-Hotels)
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- [San Eduardo Hotels ](https://www.expedia.ca/San-Eduardo-Hotels.d553248635976391803.Travel-Guide-Hotels)
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- [Tarqui Hotels ](https://www.expedia.ca/Tarqui-Guayaquil-Hotels.0-n553248635976385120-0.Travel-Guide-Filter-Hotels)
- [Urbanizacion Villa del Rey Hotels ](https://www.expedia.ca/Urbanizacion-Villa-Del-Rey-Guayaquil-Hotels.0-n553248635976397967-0.Travel-Guide-Filter-Hotels)
- [Urdesa Hotels ](https://www.expedia.ca/Urdesa-Guayaquil-Hotels.0-n553248633981744847-0.Travel-Guide-Filter-Hotels)

- [Flights to Guayaquil ](https://www.expedia.ca/Cheap-Flights-To-Guayaquil.d6337570.Travel-Guide-Flights)
- [Flights to Jose Joaquin de Olmedo Intl. ](https://www.expedia.ca/Cheap-Flights-To-Jose-Joaquin-De-Olmedo-Intl.d4544839.Travel-Guide-Flights)
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- [Flights from Thunder Bay (YQT) to Guayaquil (GYE) ](https://www.expedia.ca/lp/flights/yqt/gye/thunder-bay-to-guayaquil)
- [Flights from Toronto (YTZ) to Guayaquil (GYE) ](https://www.expedia.ca/lp/flights/ytz/gye/toronto-to-guayaquil)
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- [Antonio Neumane Park ](https://www.expedia.ca/Antonio-Neumane-Park-Kennedy.d6331057.Vacation-Attraction)
- [Visit Garzota ](https://www.expedia.ca/Guayaquil-Garzota.dx553248633981707957)
- [Visit Guayaquil ](https://www.expedia.ca/Guayaquil.dx6337570)
- [Urdesa Vacations ](https://www.expedia.ca/Urdesa.d553248633981744847.Destination-Travel-Guides)

- [Car rental Guayaquil ](https://www.expedia.ca/Car-Rentals-In-Guayaquil.d6337570.Car-Rental-Guide)
- [Rental cars Jose Joaquin de Olmedo Intl. airport ](https://www.expedia.ca/Car-Rentals-In-Jose-Joaquin-De-Olmedo-Intl.d4544839.Car-Rental-Guide)
- [Car rentals near Kennedy ](https://www.expedia.ca/Car-Rentals-In-Kennedy.d553248633981744623.Car-Rental-Guide)
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- [Luxury Car Rentals in Guayaquil ](https://www.expedia.ca/Luxury-Car-Rentals-In-Guayaquil.d6337570-tLuxury.Car-Rental-Guide-Class)

- [Guayaquil Vacation Rentals ](https://www.expedia.ca/Guayaquil-Vacation-Rentals.d6337570.Travel-Guide-VacationRentals)

- [Things to do in Guayaquil ](https://www.expedia.ca/Things-To-Do-In-Guayaquil.d6337570.Travel-Guide-Activities)