Title: Lignumvitae Key Botanical State Park Vacation Home Rentals from CA $715: Search Top Private Vacation Homes for Rent | Expedia.ca [Lignumvitae Key Botanical State Park Travel Guide](https://expedia.ca/Lignumvitae-Key-Botanical-State-Park.dx553248621532652349)[Hotels in Lignumvitae Key Botanical State Park](https://expedia.ca/Lignumvitae-Key-Botanical-State-Park-Hotels.d553248621532652349.Travel-Guide-Hotels)[Vacation Rentals in Lignumvitae Key Botanical State Park](https://expedia.ca/Lignumvitae-Key-Botanical-State-Park-Vacation-Rentals.d553248621532652349.Travel-Guide-VacationRentals)[Flights to Lignumvitae Key Botanical State Park](https://expedia.ca/Cheap-Flights-To-Lignumvitae-Key-Botanical-State-Park.d553248621532652349.Travel-Guide-Flights)[Lignumvitae Key Botanical State Park Car Rentals](https://expedia.ca/Car-Rentals-In-Lignumvitae-Key-Botanical-State-Park.d553248621532652349.Car-Rental-Guide)[Lignumvitae Key Botanical State Park Vacation Packages](https://expedia.ca/Lignumvitae-Key-Botanical-State-Park.d553248621532652349.Destination-Travel-Guides) ![3/4 of a mile paddle from islamorada. There are still ruins and one grave with historic markers from the early settlements of Indians, spanish and american ship wreckers. The island is accessible by paddling or boat.](https://images.trvl-media.com/place/10768/cc086a75-d19c-4609-99ea-434de5d33788.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by RVOutlawz ![](https://images.trvl-media.com/place/10768/cc086a75-d19c-4609-99ea-434de5d33788.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=553248621532652349&startDate=2026-02-13&endDate=2026-02-15&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Mar 27 - Mar 29](https://www.expedia.ca/Hotel-Search?regionId=553248621532652349&startDate=2026-03-27&endDate=2026-03-29&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Apr 24 - Apr 26](https://www.expedia.ca/Hotel-Search?regionId=553248621532652349&startDate=2026-04-24&endDate=2026-04-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [May 22 - May 24](https://www.expedia.ca/Hotel-Search?regionId=553248621532652349&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Lignumvitae Key Botanical State Park vacation homes ![Smart TV](https://images.trvl-media.com/lodging/100000000/99970000/99961500/99961430/006a1068.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/100000000/99970000/99961500/99961430/b3fdbd21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/100000000/99970000/99961500/99961430/301698a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/100000000/99970000/99961500/99961430/95c54ed2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming Home in Key Largo [](https://www.expedia.ca/Key-Largo-Hotels-Charming-Home-In-Key-Largo.h99961430.Hotel-Information) Key Largo 9.8/10 Exceptional (30 reviews) "Great location. Very clean very nice, stay there again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark B. CA $299 CA $735 total includes taxes & fees Feb 12 - Feb 13 [](https://www.expedia.ca/Key-Largo-Hotels-Charming-Home-In-Key-Largo.h99961430.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/40000000/39860000/39854400/39854350/119dae30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/40000000/39860000/39854400/39854350/2824ed80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/40000000/39860000/39854400/39854350/ba3ae0e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/40000000/39860000/39854400/39854350/5c177f3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waterfront Pool, Beach, Dock, Kayaks [](https://www.expedia.ca/Key-Largo-Hotels-Waterfront-Pool.h39854350.Hotel-Information) Key Largo 9.8/10 Exceptional (80 reviews) "Had a great time property was exactly as described. Would stay again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael S. CA $352 CA $751 total includes taxes & fees Feb 3 - Feb 4 [](https://www.expedia.ca/Key-Largo-Hotels-Waterfront-Pool.h39854350.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/25000000/24210000/24204500/24204423/32bcd8a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/25000000/24210000/24204500/24204423/033a0c45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/25000000/24210000/24204500/24204423/49f2540a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/25000000/24210000/24204500/24204423/22ec185f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Largo [](https://www.expedia.ca/Key-Largo-Hotels-Relax-And-Enjoy-Beautiful-Key-Largo-Townhome.h24204423.Hotel-Information) Key Largo 9.0/10 Wonderful (129 reviews) "Very nice updated home in a nice community with views to the lagoon. Would definitely stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Priscilla G. CA $325 CA $739 total includes taxes & fees Jan 27 - Jan 28 [](https://www.expedia.ca/Key-Largo-Hotels-Relax-And-Enjoy-Beautiful-Key-Largo-Townhome.h24204423.Hotel-Information) ![Beach towels](https://images.trvl-media.com/lodging/91000000/90180000/90174100/90174063/8b761761.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/91000000/90180000/90174100/90174063/421c20bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/91000000/90180000/90174100/90174063/7d3c5406.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/91000000/90180000/90174100/90174063/c885e15a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### New Tiny Home- Paddle Boards, Kayaks, Pool, Marina [](https://www.expedia.ca/Key-Largo-Hotels-New-Tiny-Home-Paddle-Boards.h90174063.Hotel-Information) Key Largo 9.6/10 Exceptional (88 reviews) "Great location! Super quiet and relaxing area! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Devin H. CA $324 CA $715 total includes taxes & fees Feb 26 - Feb 27 [](https://www.expedia.ca/Key-Largo-Hotels-New-Tiny-Home-Paddle-Boards.h90174063.Hotel-Information) ![1 bedroom, bed sheets](https://images.trvl-media.com/lodging/106000000/105570000/105563400/105563360/9ed9fba1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/106000000/105570000/105563400/105563360/954a928d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/106000000/105570000/105563400/105563360/03022632.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/106000000/105570000/105563400/105563360/c0919969.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Premium Floating Bugalow by Stay Ombi in the Keys with Stunning Ocean Views. [](https://www.expedia.ca/Key-Largo-Hotels-Premium-Floating-Bugalow-By-Stay-Ombi-In-The-Keys-With-Stunning-Ocean-Views.h105563360.Hotel-Information) Key Largo Village CA $1,794 CA $2,152 total includes taxes & fees Jan 27 - Jan 28 [](https://www.expedia.ca/Key-Largo-Hotels-Premium-Floating-Bugalow-By-Stay-Ombi-In-The-Keys-With-Stunning-Ocean-Views.h105563360.Hotel-Information) ![Beach nearby, sun loungers, beach towels](https://images.trvl-media.com/lodging/28000000/27450000/27442300/27442290/d90cad76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/28000000/27450000/27442300/27442290/69ad98a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/28000000/27450000/27442300/27442290/cdc89db9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27450000/27442300/27442290/784806b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### LICENSED MANAGER - MODERN 2/2 COCONUT PALM VILLA - OCEANFRONT BEACH RESORT! [](https://www.expedia.ca/Key-Largo-Hotels-LICENSED-MANAGER-MODERN-22-COCONUT-PALM-VILLA-OCEANFRONT-BEACH-RESORT.h27442290.Hotel-Information) Key Largo 9.4/10 Exceptional (62 reviews) "Easy clean condo " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephen G. CA $455 CA $1,011 total includes taxes & fees Jan 31 - Feb 1 [](https://www.expedia.ca/Key-Largo-Hotels-LICENSED-MANAGER-MODERN-22-COCONUT-PALM-VILLA-OCEANFRONT-BEACH-RESORT.h27442290.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/121000000/120630000/120624700/120624610/396e03e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/121000000/120630000/120624700/120624610/3bdab314.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/120630000/120624700/120624610/0915fdf4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/121000000/120630000/120624700/120624610/w1078h802x1y198-a3a83b11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NEW ! Lagoon-front townhouse with Marina! Day Dreams Key Largo. [](https://www.expedia.ca/Key-Largo-Hotels-Marvelous-2-Bedroom-House-With-AC-In-Key-Largo.h120624610.Hotel-Information) Key Largo 10/10 Exceptional (46 reviews) "Good location. Lagoon and pool right outside door. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra C. CA $370 CA $813 total includes taxes & fees Jan 27 - Jan 28 [](https://www.expedia.ca/Key-Largo-Hotels-Marvelous-2-Bedroom-House-With-AC-In-Key-Largo.h120624610.Hotel-Information) ![On the beach, sun loungers, beach towels](https://images.trvl-media.com/lodging/35000000/34150000/34143300/34143275/ee01b3bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, travel crib, free WiFi](https://images.trvl-media.com/lodging/35000000/34150000/34143300/34143275/237e34eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, a heated pool](https://images.trvl-media.com/lodging/35000000/34150000/34143300/34143275/cdbcc55f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/35000000/34150000/34143300/34143275/b96653e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NEW! CASA PALMA OCEANSIDE -GOLF CART, 2 KING SUITES, POOL, BEACH, PICKLE, KAYAKS [](https://www.expedia.ca/Key-Largo-Hotels-Casa-Palma-Live-THE-Lavish-Keys-Life-Vibrant.h34143275.Hotel-Information) Key Largo 9.8/10 Exceptional (170 reviews) "Loved this place and will stay again if we go back to the Keys. Gated community with golf cart to go to the pier with great community resources, grills and sitting areas. Favorite part was the lagoon in the middle of the community not far from the screened in back porch. Full of fish you can swim with and calm beach area that is clean and nice with shade when you need it. We didn’t want to leave this place. Highly recommend!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chandler G. CA $609 CA $1,250 total includes taxes & fees Jan 29 - Jan 30 [](https://www.expedia.ca/Key-Largo-Hotels-Casa-Palma-Live-THE-Lavish-Keys-Life-Vibrant.h34143275.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/68000000/67390000/67389700/67389654/bc33b00f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/68000000/67390000/67389700/67389654/b484f538.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/68000000/67390000/67389700/67389654/782de557.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/68000000/67390000/67389700/67389654/3d66974c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Overlooking Saltwater Lagoon Free Kayaks Renovated [](https://www.expedia.ca/Key-Largo-Hotels-Overlooking-Saltwater-Lagoon-Free-Kayaks-Renovated.h67389654.Hotel-Information) Key Largo 9.6/10 Exceptional (46 reviews) "Absolutely perfect trip. The house was clean and had everything we needed. Its a great location too!" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Jill D. CA $589 CA $1,335 total includes taxes & fees Feb 10 - Feb 11 [](https://www.expedia.ca/Key-Largo-Hotels-Overlooking-Saltwater-Lagoon-Free-Kayaks-Renovated.h67389654.Hotel-Information) ![On the beach, sun loungers, beach towels](https://images.trvl-media.com/lodging/35000000/34150000/34140800/34140748/2ef98d02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books, music library, video library](https://images.trvl-media.com/lodging/35000000/34150000/34140800/34140748/8cebb21d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/35000000/34150000/34140800/34140748/5d0da2ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/35000000/34150000/34140800/34140748/e5f0537a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NEW! CASA AZUL OCEANSIDE - GOLF CART, 2 KING SUITES, POOL, BEACH, PICKLE, KAYAKS [](https://www.expedia.ca/Key-Largo-Hotels-Casa-Azul-THE-Salt-Life-Meets-Luxury-Chic-With-Beachy-Vibes-Free-Golf-Cart.h34140748.Hotel-Information) Key Largo 9.8/10 Exceptional (194 reviews) "Very relaxing vacation " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Teresa M. CA $541 CA $1,164 total includes taxes & fees Jan 27 - Jan 28 [](https://www.expedia.ca/Key-Largo-Hotels-Casa-Azul-THE-Salt-Life-Meets-Luxury-Chic-With-Beachy-Vibes-Free-Golf-Cart.h34140748.Hotel-Information) ![A heated pool](https://images.trvl-media.com/lodging/73000000/72660000/72653600/72653526/78bddc27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, travel crib, free WiFi](https://images.trvl-media.com/lodging/73000000/72660000/72653600/72653526/2d0fd435.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, foosball](https://images.trvl-media.com/lodging/73000000/72660000/72653600/72653526/aaa95a27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/73000000/72660000/72653600/72653526/3c06d12a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beautiful Oceanside Mariner\`s 3 Bedroom Townhome [](https://www.expedia.ca/Key-Largo-Hotels-Beautiful-Oceanside-Mariners-3-Bedroom-Townhome.h72653526.Hotel-Information) Rock Harbor 10/10 Exceptional (90 reviews) "Great place, great hosts. We'll probably be backThank you" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Curt B. CA $477 CA $973 total includes taxes & fees Feb 4 - Feb 5 [](https://www.expedia.ca/Key-Largo-Hotels-Beautiful-Oceanside-Mariners-3-Bedroom-Townhome.h72653526.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/69000000/68910000/68907000/68906944/w1123h750x106y0-d60943bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/69000000/68910000/68907000/68906944/w1124h750x105y0-bf46509c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach nearby, beach towels](https://images.trvl-media.com/lodging/69000000/68910000/68907000/68906944/7c43b63d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/69000000/68910000/68907000/68906944/w1123h750x106y0-b71fa06d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villa 5053 on Duck Key Boat Slip Available - 2BD 2.5BA [](https://www.expedia.ca/Marathon-Hotels-Townhouse-On-Duck-Key.h68906944.Hotel-Information) Duck Key 9.6/10 Exceptional (46 reviews) "Clean property! Great views! Great communication with owner! Perfect location- close to marathon and key west! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) candi b. CA $574 CA $1,119 total includes taxes & fees Feb 3 - Feb 4 [](https://www.expedia.ca/Marathon-Hotels-Townhouse-On-Duck-Key.h68906944.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/33000000/32650000/32643200/32643137/53c2716d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, jetted tub, hair dryer, towels](https://images.trvl-media.com/lodging/33000000/32650000/32643200/32643137/cb040538.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/33000000/32650000/32643200/32643137/deb34f23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/33000000/32650000/32643200/32643137/dcd685ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Grand Lodge Right On The Water at Largo Resort [](https://www.expedia.ca/Key-Largo-Hotels-The-Grand-Lodge-Right-On-The-Water-At-Largo-Resort-By-Rentyl-Resorts.h32643137.Hotel-Information) Key Largo 9.6/10 Exceptional (4 reviews) "would stay again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jonathan G. CA $2,259 CA $2,953 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Key-Largo-Hotels-The-Grand-Lodge-Right-On-The-Water-At-Largo-Resort-By-Rentyl-Resorts.h32643137.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/83000000/82780000/82770600/82770543/24ea9ac4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/83000000/82780000/82770600/82770543/4f449761.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, offices](https://images.trvl-media.com/lodging/83000000/82780000/82770600/82770543/dc9a487d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach](https://images.trvl-media.com/lodging/83000000/82780000/82770600/82770543/6004bd91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tiny Villa, Big Ocean Views| Breathtaking Sunsets [](https://www.expedia.ca/Marathon-Hotels-Tiny-Villa.h82770543.Hotel-Information) Duck Key 10/10 Exceptional (14 reviews) "Beautiful views. Very nice accommodations. Wonderfull location!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) michael h. CA $344 CA $782 total includes taxes & fees Jan 27 - Jan 28 [](https://www.expedia.ca/Marathon-Hotels-Tiny-Villa.h82770543.Hotel-Information) ![TV](https://images.trvl-media.com/lodging/62000000/61110000/61104000/61103908/c3bc15b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/62000000/61110000/61104000/61103908/c0162c20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/62000000/61110000/61104000/61103908/6791a968.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/62000000/61110000/61104000/61103908/c083fec1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villa 5020 on Duck Key Boat Slip Available - 2BD 2.5BA [](https://www.expedia.ca/Marathon-Hotels-Condo-In-Duck-Key.h61103908.Hotel-Information) Duck Key 8.4/10 Very good (10 reviews) "Unit was very clean and had everything we needed" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vanessa L. CA $382 CA $875 total includes taxes & fees Jan 29 - Jan 30 [](https://www.expedia.ca/Marathon-Hotels-Condo-In-Duck-Key.h61103908.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/70000000/69770000/69765400/69765375/ebe4d5b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/70000000/69770000/69765400/69765375/4b4a1c4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/70000000/69770000/69765400/69765375/4c3b42d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/70000000/69770000/69765400/69765375/9feccd51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villa 5023 on Duck Key Boat Slip Available - 2BD 1.5BA [](https://www.expedia.ca/Marathon-Hotels-Villa-On-Duck-Key.h69765375.Hotel-Information) Duck Key 9.4/10 Exceptional (32 reviews) "A short weekend getaway was made perfect in this villa. The location is idyllic; especially the balcony overlooking the bay with a perfect sunset view. The home was well-appointed, simple yet all the necessities were covered. Communication with the property manager was excellent. Definitely will book again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Natasha A. CA $374 CA $865 total includes taxes & fees Jan 27 - Jan 28 [](https://www.expedia.ca/Marathon-Hotels-Villa-On-Duck-Key.h69765375.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/118000000/117810000/117803800/117803749/d4871fe1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/118000000/117810000/117803800/117803749/102b5073.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/118000000/117810000/117803800/117803749/ad5f6fbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, oven, stovetop, dishwasher](https://images.trvl-media.com/lodging/118000000/117810000/117803800/117803749/110664ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 2-bedroom townhome in pleasant gated community located in Key Largo [](https://www.expedia.ca/Key-Largo-Hotels-2-Bedroom-Townhome-In-Pleasant-Gated-Community-Located-In-Key-Largo.h117803749.Hotel-Information) Key Largo CA $448 CA $826 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Key-Largo-Hotels-2-Bedroom-Townhome-In-Pleasant-Gated-Community-Located-In-Key-Largo.h117803749.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/92000000/91220000/91218300/91218247/a0c8fd9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/92000000/91220000/91218300/91218247/3ed7dcd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/92000000/91220000/91218300/91218247/174d9f13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/92000000/91220000/91218300/91218247/0c7fe866.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tropical House By The Shore at Largo Resort [](https://www.expedia.ca/Key-Largo-Hotels-Tropical-House-By-The-Shore-At-Largo-Resort-By-Rentyl-Resorts.h91218247.Hotel-Information) Key Largo CA $1,095 CA $1,489 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Key-Largo-Hotels-Tropical-House-By-The-Shore-At-Largo-Resort-By-Rentyl-Resorts.h91218247.Hotel-Information) ![1 bedroom, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/35000000/34550000/34548900/34548876/472b31db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/35000000/34550000/34548900/34548876/b4f9ab10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/35000000/34550000/34548900/34548876/6781facc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels](https://images.trvl-media.com/lodging/35000000/34550000/34548900/34548876/eeb33358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Serene Bungalow in Paradise at Largo Resort [](https://www.expedia.ca/Key-Largo-Hotels-Serene-Bungalow-In-Paradise-At-Largo-Resort-By-Rentyl-Resorts.h34548876.Hotel-Information) Key Largo 10/10 Exceptional (2 reviews) " We regret that we only booked for one night. We will definitely return for a longer stay. Everything about Key Largo Resort was perfect! The setting, the location, the accommodations, everything! Thank you for an amazing experience! We will be back! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly V. CA $588 CA $844 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Key-Largo-Hotels-Serene-Bungalow-In-Paradise-At-Largo-Resort-By-Rentyl-Resorts.h34548876.Hotel-Information) ![A heated pool](https://images.trvl-media.com/lodging/33000000/32180000/32179700/32179681/4c8b67b3_edited_416f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/33000000/32180000/32179700/32179681/9da6d310_edited_0408.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/33000000/32180000/32179700/32179681/3b8e5bf8_edited_7abc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sun loungers, beach towels](https://images.trvl-media.com/lodging/33000000/32180000/32179700/32179681/9ce2d3fd_edited_d426.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spacious 4BR/3BA • 8 Beds • Mariner’s Club Community • Perfect for Large Groups [](https://www.expedia.ca/Key-Largo-Hotels-Spacious-4BR3BA-8-Beds-Mariners-Club-Community-Perfect-For-Large-Groups.h32179681.Hotel-Information) Rock Harbor 10/10 Exceptional (71 reviews) "Well organized, clean, beds and pillows were very comfortable, quit and very relaxing.If you are looking for a place to stay while diving, I would highly recommend staying here." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tracy M. CA $808 CA $1,827 total includes taxes & fees Feb 12 - Feb 13 [](https://www.expedia.ca/Key-Largo-Hotels-Spacious-4BR3BA-8-Beds-Mariners-Club-Community-Perfect-For-Large-Groups.h32179681.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-09&endDate=2026-02-10®ionId=553248621532652349&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find vacation rentals that suit your style Aparthotels [](https://www.expedia.ca/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America®ionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2026-04-26&d1=2026-04-26&endDate=2026-04-29&d2=2026-04-29&lodging=APART_HOTEL) Apartments [](https://www.expedia.ca/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America®ionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2026-04-26&d1=2026-04-26&endDate=2026-04-29&d2=2026-04-29&lodging=APARTMENT) Villas [](https://www.expedia.ca/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America®ionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2026-04-26&d1=2026-04-26&endDate=2026-04-29&d2=2026-04-29&lodging=VILLA) Condos [](https://www.expedia.ca/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America®ionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2026-04-26&d1=2026-04-26&endDate=2026-04-29&d2=2026-04-29&lodging=CONDO) Cottages [](https://www.expedia.ca/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America®ionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2026-04-26&d1=2026-04-26&endDate=2026-04-29&d2=2026-04-29&lodging=COTTAGE) Private vacation homes [](https://www.expedia.ca/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America®ionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2026-04-26&d1=2026-04-26&endDate=2026-04-29&d2=2026-04-29&lodging=VACATION_HOME) Houseboats [](https://www.expedia.ca/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America®ionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2026-04-26&d1=2026-04-26&endDate=2026-04-29&d2=2026-04-29&lodging=HOUSE_BOAT) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLignumvitae-Key-Botanical-State-Park-Private-Vacation-Homes.d553248621532652349-aaPrivateVacationHomes.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLignumvitae-Key-Botanical-State-Park-Private-Vacation-Homes.d553248621532652349-aaPrivateVacationHomes.Travel-Guide-Accommodation) ## Top Lignumvitae Key Botanical State Park Hotel Reviews ![Lime Tree Bay Resort](https://images.trvl-media.com/lodging/1000000/890000/882300/882254/6f2246e8_y.jpg) ### Lime Tree Bay Resort 10/10 Excellent "We stay one night but it was great. It was very clean and it had the space we need it. The front desk staff were friendly and welcoming. This is the 4th time we stay at The Lime Tree Bay Resort." [](https://expedia.ca/Long-Key-Hotels-Lime-Tree-Bay-Resort.h882254.Hotel-Information) ![Chesapeake Beach Resort](https://images.trvl-media.com/lodging/1000000/10000/4200/4170/689f4306_y.jpg) ### Chesapeake Beach Resort 10/10 Excellent "Staff was very nice. Nice to use the complimentary clear bottom kayaks. Breakfast was good, Didi made a great omelette!" [](https://expedia.ca/Islamorada-Hotels-Chesapeake-Beach-Resort.h4170.Hotel-Information) ![Marina Del Mar Resort and Marina](https://images.trvl-media.com/lodging/1000000/10000/5200/5114/d42f8885_y.jpg) ### Marina Del Mar Resort and Marina 10/10 Excellent "Super clean room. Staff was great and very helpful. Beautiful view. Walking distance from restaurant." [](https://expedia.ca/Key-Largo-Hotels-Marina-Del-Mar-Resort-And-Marina.h5114.Hotel-Information) ![Drift Hotel](https://images.trvl-media.com/lodging/14000000/13210000/13209600/13209518/f3e504e7_y.jpg) ### Drift Hotel 10/10 Excellent "Amazing experience and amenities. " [](https://expedia.ca/Key-Largo-Hotels-Drift-Hotel.h13209518.Hotel-Information) ![Ocean Pointe Suites at Key Largo](https://images.trvl-media.com/lodging/1000000/10000/5600/5502/c6c81bd5_y.jpg) ### Ocean Pointe Suites at Key Largo 10/10 Excellent "Amazing" [](https://expedia.ca/Tavernier-Hotels-Ocean-Pointe-Suites-At-Key-Largo.h5502.Hotel-Information) ![Cheeca Lodge & Spa](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/617c0723_y.jpg) ### Cheeca Lodge & Spa 10/10 Excellent "This palce is awesome. Clean rooms. 2 large pools with a view. Covered garage spot. " [](https://expedia.ca/Islamorada-Hotels-Cheeca-Lodge-Spa.h5780.Hotel-Information) ![Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort](https://images.trvl-media.com/lodging/1000000/20000/11900/11864/d10a018b_y.jpg) ### Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort 10/10 Excellent "Great place" [](https://expedia.ca/Islamorada-Hotels-Three-Waters-Resort-And-Marina.h11864.Hotel-Information) ![The Pelican Key Largo Cottages](https://images.trvl-media.com/lodging/7000000/6840000/6839400/6839376/f35b06df_y.jpg) ### The Pelican Key Largo Cottages 10/10 Excellent "The property was a little bit hard to find, but the check-in experience was great, very friendly staff. The property is a set of quaint old cottages, a throwback to the 50s; Hemmingway and Bogart could’ve stayed here. The rooms were very clean, and updated for a budget motel. The boat ramp and Gulf view were absolutely beautiful. I’m sad I did not get to use the free kayaks." [](https://expedia.ca/Key-Largo-Hotels-The-Pelican-Key-Largo-Cottages.h6839376.Hotel-Information) ![Islander Resort](https://images.trvl-media.com/lodging/1000000/480000/475500/475438/5adae4af_y.jpg) ### Islander Resort 10/10 Excellent "This place is great. A must stay. Everyone is so friendly. Place is spotless clean" [](https://expedia.ca/Islamorada-Hotels-Islander-Resort.h475438.Hotel-Information) ## Find out more about Lignumvitae Key Botanical State Park ## Lignumvitae Key Botanical State Park Vacation Homes information | Number of reviews | 1,004 | | ----------------- | ------------------ | | Accommodation | 676 Vacation Homes | | Lowest Price | CA $715 | | Highest Price | CA $2,953 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [Hotels near Bud n' Mary's Dive Center ](https://www.expedia.ca/Bud-N-Marys-Dive-Center-Hotels.0-l6069243-0.Travel-Guide-Filter-Hotels) - [B&B in Coopertown ](https://www.expedia.ca/Coopertown-Bed-And-Breakfast.d6177715-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Guest Houses in Coopertown ](https://www.expedia.ca/Coopertown-Guest-Houses.d6177715-aaGuestHouses.Travel-Guide-Accommodation) - [B&B in Elliott Key ](https://www.expedia.ca/Elliott-Key-Bed-And-Breakfast.d553248621532652848-aaBedAndBreakfast.Travel-Guide-Accommodation) - 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