Title: Book the Best BUSINESS Hotels in Panhandle Plains in 2026 | Expedia.ca [Panhandle Plains Travel Guide](https://expedia.ca/Panhandle-Plains.dx6058805)[Hotels in Panhandle Plains](https://expedia.ca/Panhandle-Plains-Hotels.d6058805.Travel-Guide-Hotels)[Vacation Rentals in Panhandle Plains](https://expedia.ca/Panhandle-Plains-Vacation-Rentals.d6058805.Travel-Guide-VacationRentals)[Flights to Panhandle Plains](https://expedia.ca/Cheap-Flights-To-Panhandle-Plains.d6058805.Travel-Guide-Flights)[Panhandle Plains Car Rentals](https://expedia.ca/Car-Rentals-In-Panhandle-Plains.d6058805.Car-Rental-Guide)[Panhandle Plains Vacation Packages](https://expedia.ca/Panhandle-Plains.d6058805.Destination-Travel-Guides) ![Lubbock which includes a windmill and tranquil scenes](https://images.trvl-media.com/place/6131013/17de49c6-a1c8-47d1-b6c1-9dad01a3e5c3.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Courtesy of Visit Lubbock ![](https://images.trvl-media.com/place/6131013/17de49c6-a1c8-47d1-b6c1-9dad01a3e5c3.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Panhandle Plains Business Hotels Tonight [Feb 4 - Feb 5](https://www.expedia.ca/Hotel-Search?regionId=6058805&startDate=2026-02-04&endDate=2026-02-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Feb 5 - Feb 6](https://www.expedia.ca/Hotel-Search?regionId=6058805&startDate=2026-02-05&endDate=2026-02-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6058805&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=6058805&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Panhandle Plains business-friendly hotels ![Lobby](https://images.trvl-media.com/lodging/2000000/1070000/1068900/1068876/7a9aad1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1070000/1068900/1068876/e0486787.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/2000000/1070000/1068900/1068876/97078764.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/2000000/1070000/1068900/1068876/885f0b6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Red River Inn [](https://www.expedia.ca/Childress-Hotels-Best-Western-Plus-Red-River-Inn.h1068876.Hotel-Information) Clarendon 9.4/10 Exceptional (979 reviews) "Staff was friendly, room was clean, breakfast was fresh and tasty" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Russell CA $183 CA $207 total includes taxes & fees Feb 6 - Feb 7 [](https://www.expedia.ca/Childress-Hotels-Best-Western-Plus-Red-River-Inn.h1068876.Hotel-Information) ![37-inch LCD TV with cable channels, TV, iPod dock](https://images.trvl-media.com/lodging/5000000/4280000/4270900/4270804/afe1eae2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/5000000/4280000/4270900/4270804/1946cd63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4280000/4270900/4270804/5b0048f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/5000000/4280000/4270900/4270804/405c342e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Amarillo West by IHG [](https://www.expedia.ca/Amarillo-Hotels-Holiday-Inn-Express-Hotel-Suites-Amarillo-West.h4270804.Hotel-Information) Amarillo 9.4/10 Exceptional (2,083 reviews) "The stay was perfect and the breakfast was great!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Frankie CA $142 CA $163 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Amarillo-Hotels-Holiday-Inn-Express-Hotel-Suites-Amarillo-West.h4270804.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/17000000/16280000/16272200/16272130/a6ba0dcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/17000000/16280000/16272200/16272130/00d31cc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/17000000/16280000/16272200/16272130/0a64570a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/17000000/16280000/16272200/16272130/f3837c6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites by Hilton Amarillo Downtown [](https://www.expedia.ca/Amarillo-Hotels-Embassy-Suites-Amarillo-Downtown.h16272130.Hotel-Information) Downtown Amarillo 9.0/10 Wonderful (1,022 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Becky CA $154 CA $179 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Amarillo-Hotels-Embassy-Suites-Amarillo-Downtown.h16272130.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/13000000/12660000/12650300/12650217/36d9c88a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/13000000/12660000/12650300/12650217/15a7a92f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/13000000/12660000/12650300/12650217/00e330b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, desk, blackout drapes](https://images.trvl-media.com/lodging/13000000/12660000/12650300/12650217/2f7d44b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Snyder [](https://www.expedia.ca/Sweetwater-Hotels-Comfort-Inn-Suites.h12650217.Hotel-Information) Snyder 9.2/10 Wonderful (567 reviews) "NIce staff, room was fine, breakfast good." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lynn CA $114 CA $131 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Sweetwater-Hotels-Comfort-Inn-Suites.h12650217.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/45000000/44380000/44370600/44370546/9ed9fb8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/45000000/44380000/44370600/44370546/99357c1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, free WiFi](https://images.trvl-media.com/lodging/45000000/44380000/44370600/44370546/16855c6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 6:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/45000000/44380000/44370600/44370546/f8cb3c8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Amarillo-West [](https://www.expedia.ca/Amarillo-Hotels-Hyatt-Place-Amarillo-West.h44370546.Hotel-Information) Amarillo 9.2/10 Wonderful (1,394 reviews) "Courteous and welcoming staff, very clean rooms, comfortable beds!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jodi CA $120 CA $141 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Amarillo-Hotels-Hyatt-Place-Amarillo-West.h44370546.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/5000000/4530000/4525900/4525899/w5754h3835x5y5-dac409e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/5000000/4530000/4525900/4525899/w5755h3835x5y5-3f5b4528.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Non Smoking](https://images.trvl-media.com/lodging/5000000/4530000/4525900/4525899/w5760h3835x0y5-04c9934a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/5000000/4530000/4525900/4525899/w5755h3835x5y5-9bbc7bfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Vernon [](https://www.expedia.ca/Childress-Hotels-Hampton-Inn-Vernon.h4525899.Hotel-Information) Vernon 9.4/10 Exceptional (752 reviews) "Clean room and great breakfast. Enjoyed the stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ALI CA $225 CA $258 total includes taxes & fees Feb 26 - Feb 27 [](https://www.expedia.ca/Childress-Hotels-Hampton-Inn-Vernon.h4525899.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1190000/1184000/1183905/0abb04c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1190000/1184000/1183905/4a9a0279.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1190000/1184000/1183905/43f91e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1190000/1184000/1183905/cdb90461.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Amarillo I-40 West, TX [](https://www.expedia.ca/Amarillo-Hotels-Country-Inn-Suites-By-Radisson.h1183905.Hotel-Information) Amarillo 9.0/10 Wonderful (2,470 reviews) "Room, amenities and service was great! The breakfast was delicious different things each day, the place was calm and quiet, the pool and spa was super nice despite the weather was great having the opportunity to play and relax in the pool." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jorge S CA $94 CA $108 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Amarillo-Hotels-Country-Inn-Suites-By-Radisson.h1183905.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/14000000/13350000/13340500/13340452/e2b5d045.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/14000000/13350000/13340500/13340452/dae19d74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/14000000/13350000/13340500/13340452/3c23f4e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/14000000/13350000/13340500/13340452/c191d5b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Pampa [](https://www.expedia.ca/Pampa-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Pampa.h13340452.Hotel-Information) Pampa 9.0/10 Wonderful (480 reviews) "Yes the room was clean and the staff was very friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gloria CA $115 CA $132 total includes taxes & fees Feb 7 - Feb 8 [](https://www.expedia.ca/Pampa-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Pampa.h13340452.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/30000/27500/27413/cd04a6c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/27500/27413/253acd8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/27500/27413/f63fa790.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/27500/27413/2aa9ddc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Dalhart [](https://www.expedia.ca/Dalhart-Hotels-Days-Inn-By-Wyndham-Dalhart.h27413.Hotel-Information) Dalhart 8.0/10 Very good (786 reviews) "Clean room and friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike CA $135 CA $153 total includes taxes & fees Feb 8 - Feb 9 [](https://www.expedia.ca/Dalhart-Hotels-Days-Inn-By-Wyndham-Dalhart.h27413.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/10000000/9790000/9784700/9784700/f7c2391f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Non Smoking (Mobility,Hearing,Tub w/Grab Bars)](https://images.trvl-media.com/lodging/10000000/9790000/9784700/9784700/c684b7d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed, Non Smoking](https://images.trvl-media.com/lodging/10000000/9790000/9784700/9784700/9e00856a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9790000/9784700/9784700/w2982h2000x18y0-a2c1c24b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Sweetwater [](https://www.expedia.ca/Sweetwater-Hotels-Microtel-Inn-And-Suites-By-Wyndham-Sweetwater.h9784700.Hotel-Information) Sweetwater 9.0/10 Wonderful (893 reviews) "Great amenities, staff was great room was amazing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deona CA $140 CA $161 total includes taxes & fees Feb 7 - Feb 8 [](https://www.expedia.ca/Sweetwater-Hotels-Microtel-Inn-And-Suites-By-Wyndham-Sweetwater.h9784700.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-19&endDate=2026-02-20®ionId=6058805&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Panhandle Plains Hotel Reviews ![Holiday Inn Express & Suites Amarillo West by IHG](https://images.trvl-media.com/lodging/5000000/4280000/4270900/4270804/02449019_y.jpg) ### Holiday Inn Express & Suites Amarillo West by IHG 10/10 Excellent "The room was clean and the staff was friendly." [](https://expedia.ca/Amarillo-Hotels-Holiday-Inn-Express-Hotel-Suites-Amarillo-West.h4270804.Hotel-Information) ![Embassy Suites Lubbock](https://images.trvl-media.com/lodging/1000000/850000/845600/845513/808ef5f2_y.jpg) ### Embassy Suites Lubbock 10/10 Excellent "The room was very clean. Staff was courteous." [](https://expedia.ca/Lubbock-Hotels-Embassy-Suites-Lubbock.h845513.Hotel-Information) ![Country Inn & Suites by Radisson, Amarillo I-40 West, TX](https://images.trvl-media.com/lodging/2000000/1190000/1184000/1183905/0abb04c2_y.jpg) ### Country Inn & Suites by Radisson, Amarillo I-40 West, TX 10/10 Excellent "Staff was great Room was very clean. The air conditioner / heater made hirrible noises all night long. " [](https://expedia.ca/Amarillo-Hotels-Country-Inn-Suites-By-Radisson.h1183905.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Lubbock Southwest](https://images.trvl-media.com/lodging/13000000/12840000/12835700/12835622/fffe6e17_y.jpg) ### La Quinta Inn & Suites by Wyndham Lubbock Southwest 10/10 Excellent "We had a clean spacious room with comfortable beds and pillows and the staff was friendly and helpful. The location was convenient, safe, and quiet. What more do you need?" [](https://expedia.ca/Lubbock-Hotels-Arbor-Hotel-And-Conference-Center.h12835622.Hotel-Information) ![Best Western Lubbock West Inn & Suites](https://images.trvl-media.com/lodging/13000000/12550000/12543900/12543806/85c263d8_y.jpg) ### Best Western Lubbock West Inn & Suites 10/10 Excellent "Everything is great, breakfast is great " [](https://expedia.ca/Lubbock-Hotels-Arbor-Inn-And-Suites.h12543806.Hotel-Information) ![Overton Hotel and Conference Center](https://images.trvl-media.com/lodging/3000000/2620000/2614900/2614816/5dee5023_y.jpg) ### Overton Hotel and Conference Center 10/10 Excellent "Room was clean, it was in a great location. Staff was helpful and on point. " [](https://expedia.ca/Lubbock-Hotels-Overton-Hotel-And-Conference-Center.h2614816.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Lubbock North](https://images.trvl-media.com/lodging/2000000/1550000/1546000/1545954/692e27e5_y.jpg) ### La Quinta Inn & Suites by Wyndham Lubbock North 10/10 Excellent "Clean room. Courteous staff." [](https://expedia.ca/Lubbock-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Lubbock-North.h1545954.Hotel-Information) ![MCM Elegante Suites Abilene](https://images.trvl-media.com/lodging/1000000/10000/1900/1837/6730caae_y.jpg) ### MCM Elegante Suites Abilene 10/10 Excellent "Staff was great, the bed was comfy. " [](https://expedia.ca/Abilene-Hotels-MCM-Elegante-Suites-Abilene.h1837.Hotel-Information) ![Wingate by Wyndham Lubbock near Texas Tech Univ. Medical Ctr](https://images.trvl-media.com/lodging/18000000/17190000/17180300/17180281/3d2a5d18_y.jpg) ### Wingate by Wyndham Lubbock near Texas Tech Univ. Medical Ctr 10/10 Excellent "Very very nice " [](https://expedia.ca/Lubbock-Hotels-Wingate-By-Wyndham-Lubbock-Near-Texas-Tech-Univ-Medical-Ctr.h17180281.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Panhandle Plains cost? ### What are the best business-friendly hotels in Panhandle Plains? ### How many business-friendly hotels are there in Panhandle Plains? ### What are the best cheap business-friendly hotels in Panhandle Plains? ### What are the top business-friendly motels in Panhandle Plains? ### Are there any family-friendly hotels in Panhandle Plains that are also business friendly? ### Why book your business-friendly hotel in Panhandle Plains with Expedia? ### How can I find cheap business-friendly hotels in Panhandle Plains? ### What is there to do in Panhandle Plains near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Luxury Hotels in Barrio ](https://www.expedia.ca/Barrio-Amarillo-Hotels-Luxury-Hotel.0-n897259818119798784-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - 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