Title: Eastern Panama Vacation Packages & Trips 2025/2026 from CA $1,038 | Expedia.ca [Eastern Panama Travel Guide](https://expedia.ca/Eastern-Panama.dx6246114)[Hotels in Eastern Panama](https://expedia.ca/Eastern-Panama-Hotels.d6246114.Travel-Guide-Hotels)[Vacation Rentals in Eastern Panama](https://expedia.ca/Eastern-Panama-Vacation-Rentals.d6246114.Travel-Guide-VacationRentals)[Flights to Eastern Panama](https://expedia.ca/Cheap-Flights-To-Eastern-Panama.d6246114.Travel-Guide-Flights)[Things to do in Eastern Panama](https://expedia.ca/Things-To-Do-In-Eastern-Panama.d6246114.Travel-Guide-Activities)[Eastern Panama Car Rentals](https://expedia.ca/Car-Rentals-In-Eastern-Panama.d6246114.Car-Rental-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Eastern Panama Vacation Packages ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence ### Better together Save up to CA $1,096 when you book a flight and hotel together\* ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package ### Rest easy Plan, book, and manage your trip all in one place ### Your Eastern Panama Vacation Leave all the planning to us with an Eastern Panama vacation package. With everything organized before you jet off, all you need to do is sit back, chill out and experience this destination's many wonders. Where to start your journey? In the most popular cities, of course. [Isla Tigre](https://www.expedia.ca/Isla-Tigre.d3000379099.Destination-Travel-Guides) and [Palenque](https://www.expedia.ca/Palenque.d553248623282267036.Destination-Travel-Guides) are two great places to kick off your itinerary during your trip to Eastern Panama. When it's time to stop daydreaming and start doing, Expedia will help turn your Eastern Panama vacation into reality. ## Top Eastern Panama Vacation Deals Price found within the past 48 hours. Click for updated prices. ![Mahogany Suites](https://images.trvl-media.com/lodging/119000000/118410000/118402400/118402387/ac780514_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Mahogany Suites CA $1,038 per person Dec 13 - Dec 19 found 1 day ago Roundtrip flight included Toronto (YTO) to Panama City (PTY) No reviews [](https://expedia.ca/go/package/search/FlightHotel/2025-12-13/2025-12-19/?FromAirport=YTO&Destination=PTY&NumRoom=1&NumAdult=2&NumChild=0&hotelId=118402387&paandie=true&dealMarker=Hb1gkFN3cYA42nf4d1jO0jsJC8syve1VXAFd4Q5uudCQkavjqbSpcJNnPZ_NNvda) ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo CA $1,488 per person Dec 13 - Dec 20 found 1 day ago Roundtrip flight included Toronto (YTO) to Panama City (PTY) 9/10 Wonderful! (997 reviews) The service was excellent, the staff very friendly and attentive at all times. The food was varied. The hotel was very clean. Highly recommended!!! Reviewed on Oct 5, 2025 [](https://expedia.ca/go/package/search/FlightHotel/2025-12-13/2025-12-20/?FromAirport=YTO&Destination=PTY&NumRoom=1&NumAdult=2&NumChild=0&hotelId=15683502&paandie=true&dealMarker=73w_BNPqGYLQRy9HgIHmhw6FZjfxiGHUV64pJhEj8DJla-RC-d148hS8h4ImIP_n) ![Central Hotel Bocas del Toro](https://images.trvl-media.com/lodging/115000000/114670000/114666400/114666306/6a7feca7_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Bocas del Toro CA $2,140 per person Nov 19 - Nov 24 found 1 day ago Roundtrip flight included Toronto (YTO) to Panama City (PTY) No reviews [](https://expedia.ca/go/package/search/FlightHotel/2025-11-19/2025-11-24/?FromAirport=YTO&Destination=PTY&NumRoom=1&NumAdult=2&NumChild=0&hotelId=114666306&paandie=true&dealMarker=f7ItZE713fY5k-vqiJsZn90PFcUwmP6JuOaixTYQe_y8DKqLXg_XLoZsFIlyVQnv) ![Casa Mallet by Wynwood House](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/dfb3f761_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Casa Mallet by Wynwood House Casco Viejo CA $2,164 per person Dec 13 - Dec 20 found 1 day ago Roundtrip flight included Toronto (YTO) to Panama City (PTY) 9.8/10 Exceptional! (21 reviews) It was very relaxing to stay at the historical and cutely renovated apartment. Great aesthetic. Lively apartment, very well decorated! Right the middle of everything in the beautiful town of Casco Veijo. Vibrant lanes, boutique stores, cafes and restaurants near by. We had an amazing time staying for 2 nights at this apartment. Reviewed on Jul 23, 2025 [](https://expedia.ca/go/package/search/FlightHotel/2025-12-13/2025-12-20/?FromAirport=YTO&Destination=PTY&NumRoom=1&NumAdult=2&NumChild=0&hotelId=99778891&paandie=true&dealMarker=PXT2cuIFffQ92HFdjR3tBBKTwY9z-692nVDPo71NlNpKPJFqeXYqA_BXMD73MmxN) ![Villa Botero By Casa Mojito B&B](https://images.trvl-media.com/lodging/12000000/11930000/11927200/11927153/393d35f8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Villa Botero By Casa Mojito B&B CA $1,180 per person Dec 13 - Dec 19 found 1 day ago Roundtrip flight included Toronto (YTO) to Panama City (PTY) 9.8/10 Exceptional! (60 reviews) Host was excellent. Great communication and very helpful. The rooms were nice and great value. Reviewed on Apr 18, 2025 [](https://expedia.ca/go/package/search/FlightHotel/2025-12-13/2025-12-19/?FromAirport=YTO&Destination=PTY&NumRoom=1&NumAdult=2&NumChild=0&hotelId=11927153&paandie=true&dealMarker=zz_ZjLfCw11XuQxasd3z6xRUmu_60099QMQFTmaxpEvpVnWN-Wsz-nxLdGk5x9dr) ## Ready to book your vacation to Eastern Panama? Choose your dates ## Eastern Panama Hotel Deals ![ San Blas Paradise Private Cabins on Shipwreck Island - meals included](https://images.trvl-media.com/lodging/38000000/37810000/37804600/37804534/7a4cf19e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### San Blas Paradise Private Cabins on Shipwreck Island - meals included Perro Island, Narganá, Guna Yala CA $237 CA $261 total Oct 11 - Oct 12 includes taxes & fees [](https://expedia.ca/Hotel-Search?startDate=11%2F10%2F2025&endDate=12%2F10%2F2025&selected=37804534&PinnedHotelID=37804534&HadPinnedHotel=true®ionId=6246114) ![Private Ocean-Front Cabin with private bathroom on San Blas Island](https://images.trvl-media.com/lodging/38000000/37770000/37767000/37766985/ede84b95_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Private Ocean-Front Cabin with private bathroom on San Blas Island Diablo Island, Narganá, Guna Yala CA $264 CA $290 total Oct 11 - Oct 12 includes taxes & fees [](https://expedia.ca/Hotel-Search?startDate=11%2F10%2F2025&endDate=12%2F10%2F2025&selected=37766985&PinnedHotelID=37766985&HadPinnedHotel=true®ionId=6246114) ![Ciel y Miel ](https://images.trvl-media.com/lodging/97000000/96740000/96735000/96734959/7979d8c3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Ciel y Miel Caillle Principale, Cacique, Provincia de Colón CA $654 CA $719 total Oct 11 - Oct 12 includes taxes & fees 10/10 Exceptional! (9 reviews) "All was good" Reviewed on Jul 14, 2025 [](https://expedia.ca/Hotel-Search?startDate=11%2F10%2F2025&endDate=12%2F10%2F2025&selected=96734959&PinnedHotelID=96734959&HadPinnedHotel=true®ionId=6246114) [See all 176 properties in Eastern Panama](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=11%2F10%2F2025&endDate=12%2F10%2F2025®ionId=6246114) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ## Frequently asked questions ### Can I cancel my flight booking to Eastern Panama due to COVID-19? > Our [Customer Service Portal](https://www.expedia.ca/service/?langId=1033) is where you can find useful information about canceling or changing your flight due to COVID-19. Before booking your tickets, it's wise to scroll through the terms and conditions of your airfare too. ### What's the best way to find cheap flights to Eastern Panama that have flexible change policies? > It's as easy as counting to three with Expedia. Firstly, enter your travel details and press "Search." Second step: Check the "No change fee" box under the "Flexible change policies" heading to the left of your screen. Step 3. Nab a cheap and flexible flight to Eastern Panama. ### What are some of the general tips for travelers to Eastern Panama during the COVID-19 outbreak? > COVID-19 has resulted in significant changes to the way we travel. If you plan to jet off to Eastern Panama, these tips will help you navigate the "new normal:" > > - Before you lock in a flight, find out if any travel restrictions apply — in both your destination and origin. Keep informed with the latest updates by checking government and travel websites. > - When you go through airport screening, keep your face mask on. You will be asked to lower it briefly to verify your identity. Passengers who refuse to wear a face mask may face civil penalties and may also be escorted from the building. > - Rather than handing a TSA agent your boarding pass, position it directly on the reader yourself. Once that's done, hold it up for inspection. > - TSA now allows passengers to take one container of hand sanitizer, up to 12 oz (350 ml) in size, in carry-on bags. This will need to be removed from your bag and presented for screening. > - To minimize handling during screening, place items such as your phone, keys and wallet into your carry-on instead of the bins. > - Transport all food items in a clear plastic bag and also place them in a screening bin. Keeping food separate from your carry-on means it's less likely a TSA employee will need to open and touch your bag for inspection. ### Which airlines fly to Eastern Panama? > Copa Airlines is a well-known airline servicing Eastern Panama. Search for airfares to Tocumen Intl. Airport (PTY) and you'll have 3173 Copa Airlines flights every month to choose from. ### How can I find cheap tickets to Eastern Panama? > You'll always find a fabulous deal with Expedia, but our "flexible dates" feature makes it that much easier. Enter your preferred travel date, then click on the flexible dates box above to see prices for nearby days. was the cheapest price for a flight to Eastern Panama in the last seven days. ### How much is a flight to Eastern Panama? > There were lots of low-cost fares for the taking in the last seven days, with the cost of a round-trip flight to Eastern Panama varying between and . Many lucky travelers locked in one-way flights from () for only . ### What are the most popular airports to fly into in Eastern Panama? > The main gateway to Eastern Panama, roughly 3507 flights land at Tocumen Intl. Airport (PTY) each month. Track down a top deal, book your seat and get ready to enjoy the best of this amazing region. ### When is the cheapest time to fly to Eastern Panama? > Jetting off on a Tuesday, followed by a Monday, is generally the best way to land the cheapest fare. Steer clear of the weekend if you can, because Saturday is typically the most expensive day. Spend the dollars you saved having a good time in Eastern Panama instead! ### How much is a plane ticket to Eastern Panama? > Prices varied from to over the last seven days. When you're ready to book, we'll be ready to help you pick up the best deal to Eastern Panama. ### Which airlines with flights to Eastern Panama employ COVID-19 cleanliness policies? > In order to minimize contact between passengers and cabin crew during the COVID-19 outbreak, the majority of airlines have taken social distancing and other measures to the skies. Just a few of these are: > > - Copa Airlines - this airline is known for conducting passenger temperature checks and electrostatic cleaning. > - United Airlines - this airline is known for providing passenger masks and cleaning with disinfectant. > - American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant. ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAMgAQAAAADzCzvFAAAFOElEQVR4Xu3bTW7kNhBAYRle9DJH0FF0NPbRdJQ+Qpa9MMy4fsiiKNlAIZggaL+3ibpc5OedpjOYpf4HLfPgTwSSCiQVSCqQVCCpQFKBpAJJBZIKJBVIKpBUIKlAUoGkAkkFkgokFUgqkFQgqUBSgaQCSQWSCiQVSCqQVAPysUytMr0vf9VPHwxbb7XubetrVOrfvtMrcTMICAiItcoUBARkQkp8qo5UO77Vp/yn36jIzRZi1DveBQICAiKBxKgHAuK72s2Q6xsv6luaH+yBTIGALCAgHsgUiO8uX1+xqyPy6V2+dWv62q/1Ic8gIAsIiAeygIAs/w6p843a/eDqVgUBAQHxQCoIiJZBoo74jX58ysb6270NYxCQChKBeCAaCEidkWOr7erx/kL/fjRV4maQi9FUiZtBLkZTJW4GuRhNlbgZ5GI0VeJmkIvRVImbQS5GUyVuHpDv0uM/fcVW5KdAKsg3gUQgFeSbQKJXRvSfMulx/dvkMRktcmO842t92Mh7yqe1ffJAQDwQCyQCAQGp8vb2fzbsxx35lHe8piPf0vxXkde+/naL/EmgH2xLh08gIBUEBKQFAvIhG7G7LPrleR55Oopf5W4/3uqzr5a2CgICAtICsUpbBQE5InG8tu/Ty/D21pHW74yD8h/d6oGAgFggIAvILlOQM6I9+2Fv02Wr2M5un1Z5vretp/wqepdvSSAVRNZA2haIH5dlq9jObp9Web63LRA/LstWsZ3dPq3yfG9bIH5clq1iO7t9WuX53rb+j0itD7txfMcf8613QfQdv9nc/yTQAxm3QEBsDgKigYxbvxjRNv3J19vbR29t2RJXu/Wzd9vaZdqHPRANRNv0JyB92APRQLRNfwLSh70XR8bj0vj29vRG39KD+o7Xg75R2mkQEJAKAmIHfaO00yAgulvsaW9X6TdlfaFv9Wlvb/9VAvHv08fXftwlgYCAgLgBAgKiDYinL3S/UQvE3bs9bfLDZVntRkeW4WDvPAJxAsRuBJGleQAC4oFE59GrIL57k+NaPx4j7+jqV2wfudsDWUCk040gICAgEogjmz0/5LnY8y6IjN5t683G49ankYocAwHRQCoICAiIdUSOr2qtNPcpX54diYYb28Hjb6dL8VhBPBAQEBBdiscK4v0y5MNufesvdB0Ve9rth6s83+3Z05H0KZ/84DGQSEcSCMgUSKQjCQRk6lWREp/i7a3v+H5ct+K1712OeiCnGy9GPZDTjRejHsjpxotRD+R048WoB3K68WLUAzndeDHqzUjs+lS+dVd/x/fV4//hjm/du/wq8tsdf2EQEBAQEBCQ75G5d0P0y7Omx5fJHQ/e4r4IpIIMux7IFEgFGXY9kKmXRC7yGxXR4w95kj8J6Dte/yTgI21vW+9+gQUCchEICIgEAqI3jq3DaJMb+0jdzY49ZODubstrXKqBgIDIAAREt46BgHzIbjTsfsrJm4x6caNWbLGPfnrHl/gEYoGAVBAQEKvYYh/9FkT/gtlvXGd3SN3r5LUPcgwEZA7kHAjIHMjQh/xYv2L3rdr/Gnr8Il7iDAgIiExBzrttC0QCkSnIcFx7ytvbkfiK3U9rOvJKjEFAQIZ05JUYg4CADOnIKzF+XSRypJq7tfGPiAYC0ibxCDIHAtIm8Qgy93uQY6tM7/a8yTteRro1fsXufe+CgIC0QCrIMRCQPxdIKpBUIKlAUoGkAkkFkgokFUgqkFQgqUBSgaQCSQWSCiQVSCqQVCCpQFKBpAJJBZIKJBVIKpBUIKlAUr0O8g8T6HZUKDwkuQAAAABJRU5ErkJggg==)