Title: Eastern Panama Vacation Home Rentals from CA $95: Search Top Private Vacation Homes for Rent | Expedia.ca

[Eastern Panama Travel Guide](https://expedia.ca/Eastern-Panama.dx6246114)[Hotels in Eastern Panama](https://expedia.ca/Eastern-Panama-Hotels.d6246114.Travel-Guide-Hotels)[Vacation Rentals in Eastern Panama](https://expedia.ca/Eastern-Panama-Vacation-Rentals.d6246114.Travel-Guide-VacationRentals)[Flights to Eastern Panama](https://expedia.ca/Cheap-Flights-To-Eastern-Panama.d6246114.Travel-Guide-Flights)[Things to do in Eastern Panama](https://expedia.ca/Things-To-Do-In-Eastern-Panama.d6246114.Travel-Guide-Activities)[Eastern Panama Car Rentals](https://expedia.ca/Car-Rentals-In-Eastern-Panama.d6246114.Car-Rental-Guide)[Eastern Panama Vacation Packages](https://expedia.ca/Eastern-Panama.d6246114.Destination-Travel-Guides)

![50 Shades of blue. Sailing through the San Blas Islands in Panama lets you experience  a pure paradise and crystal clear water. You can buy fresh fish and other seefood drirectly from local fishermen. If you want you can also play Robinson Crusoe on islands with literally only one palm tree. 
#BVSBlue](https://images.trvl-media.com/place/6246376/42fe0cae-c805-47d5-a705-ee119c68d58c.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Nico Barner

# Eastern Panama Vacation Rentals

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## Check prices for these dates

In two weeks

[Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2025-12-26&endDate=2025-12-28&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2026-02-06&endDate=2026-02-08&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[Mar 6 - Mar 8](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2026-03-06&endDate=2026-03-08&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Apr 3 - Apr 5](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2026-04-03&endDate=2026-04-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Eastern Panama vacation homes

![Exterior](https://images.trvl-media.com/lodging/104000000/103640000/103636800/103636720/1649bd69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, oven, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/104000000/103640000/103636800/103636720/53270734.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, oven, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/104000000/103640000/103636800/103636720/95f8bd50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/104000000/103640000/103636800/103636720/4fd01df8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Colón Province

[](https://www.expedia.ca/Cativa-Hotels-Cabana-La-Punta-Op-Het-Strand.h103636720.Hotel-Information)

CA $179

CA $236 total

includes taxes & fees

Dec 12 - Dec 13

[](https://www.expedia.ca/Cativa-Hotels-Cabana-La-Punta-Op-Het-Strand.h103636720.Hotel-Information)

![Marina](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/de84a70a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/9f704818.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/fef7062f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/a6aae70d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Garrote

[](https://www.expedia.ca/Puerto-Lindo-Hotels-Despierta-Sobre-El-Mar.h108562093.Hotel-Information)

6.0/10

(1)

CA $103

CA $148 total

includes taxes & fees

Dec 13 - Dec 14

[](https://www.expedia.ca/Puerto-Lindo-Hotels-Despierta-Sobre-El-Mar.h108562093.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/105000000/104140000/104131500/104131479/9162bab0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/105000000/104140000/104131500/104131479/a93f8aa8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/105000000/104140000/104131500/104131479/ff987ea3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/105000000/104140000/104131500/104131479/c4fb5930.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Palenque

[](https://www.expedia.ca/Caribbean-Paradise-Beachfront-Getaway.h104131479.Hotel-Information)

[](https://www.expedia.ca/Caribbean-Paradise-Beachfront-Getaway.h104131479.Hotel-Information)

![Beach](https://images.trvl-media.com/lodging/34000000/33020000/33018800/33018721/fa337c68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach](https://images.trvl-media.com/lodging/34000000/33020000/33018800/33018721/d35d5d23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![](https://images.trvl-media.com/lodging/34000000/33020000/33018800/33018721/d70c8750.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach](https://images.trvl-media.com/lodging/34000000/33020000/33018800/33018721/93d05a41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Panama , Betania

[](https://www.expedia.ca/San-Blas-Islands-Hotels-Private-Cabin-In-San-Blas.h33018721.Hotel-Information)

CA $365

CA $403 total

includes taxes & fees

Dec 12 - Dec 13

[](https://www.expedia.ca/San-Blas-Islands-Hotels-Private-Cabin-In-San-Blas.h33018721.Hotel-Information)

![Beach](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/95ace113.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/551ebe2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/30f0b989.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/14bad027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Colón Province

[](https://www.expedia.ca/Isla-Grande-Hotels-Deluxe-Beachfront-4-Bedroom-House-In-Colon-Province.h120061071.Hotel-Information)

CA $467

CA $532 total

includes taxes & fees

Dec 12 - Dec 13

[](https://www.expedia.ca/Isla-Grande-Hotels-Deluxe-Beachfront-4-Bedroom-House-In-Colon-Province.h120061071.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/46000000/45030000/45022900/45022806/743536b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/46000000/45030000/45022900/45022806/d2331d06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/46000000/45030000/45022900/45022806/810fb7dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, stovetop, cookware/dishes/utensils](https://images.trvl-media.com/lodging/46000000/45030000/45022900/45022806/38938e50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Colon

[](https://www.expedia.ca/Bouvet-Island-Hotels-Vrbo-Property.h45022806.Hotel-Information)

10/10

Exceptional

(1)

"Great. Please take care of the cat"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

KENNETH E.

CA $47

CA $95 total

includes taxes & fees

Dec 15 - Dec 16

[](https://www.expedia.ca/Bouvet-Island-Hotels-Vrbo-Property.h45022806.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/100000000/99590000/99581700/99581614/w1024h571x0y56-41b74f14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/100000000/99590000/99581700/99581614/w1024h457x0y112-fb2f99a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/100000000/99590000/99581700/99581614/w1024h570x0y57-de949b20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/100000000/99590000/99581700/99581614/w1024h571x0y56-3a60d486.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Panamá

[](https://www.expedia.ca/Caimitillo-Hotels-Hummingbird-HouseCasa-De-Colibri.h99581614.Hotel-Information)

CA $407

CA $520 total

includes taxes & fees

Dec 13 - Dec 14

[](https://www.expedia.ca/Caimitillo-Hotels-Hummingbird-HouseCasa-De-Colibri.h99581614.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/108000000/107130000/107121900/107121885/3c7390e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/108000000/107130000/107121900/107121885/1918a65d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/108000000/107130000/107121900/107121885/b19a70c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/108000000/107130000/107121900/107121885/18d63fca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Panamá

[](https://www.expedia.ca/24-De-Diciembre-Hotels-Hacienda-La-Perezosa-In-Cerro-Azul.h107121885.Hotel-Information)

CA $1,103

CA $1,372 total

includes taxes & fees

Dec 16 - Dec 17

[](https://www.expedia.ca/24-De-Diciembre-Hotels-Hacienda-La-Perezosa-In-Cerro-Azul.h107121885.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-25&endDate=2025-12-26&regionId=6246114&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

## Find vacation rentals that suit your style

Apartments

[](https://www.expedia.ca/Hotel-Search?destination=Eastern+Panama%2C+Panama&regionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-03-11&d1=2026-03-11&endDate=2026-03-14&d2=2026-03-14&lodging=APARTMENT)

Cabins

[](https://www.expedia.ca/Hotel-Search?destination=Eastern+Panama%2C+Panama&regionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-03-11&d1=2026-03-11&endDate=2026-03-14&d2=2026-03-14&lodging=CABIN)

Cottages

[](https://www.expedia.ca/Hotel-Search?destination=Eastern+Panama%2C+Panama&regionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-03-11&d1=2026-03-11&endDate=2026-03-14&d2=2026-03-14&lodging=COTTAGE)

Villas

[](https://www.expedia.ca/Hotel-Search?destination=Eastern+Panama%2C+Panama&regionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-03-11&d1=2026-03-11&endDate=2026-03-14&d2=2026-03-14&lodging=VILLA)

Condos

[](https://www.expedia.ca/Hotel-Search?destination=Eastern+Panama%2C+Panama&regionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-03-11&d1=2026-03-11&endDate=2026-03-14&d2=2026-03-14&lodging=CONDO)

Private vacation homes

[](https://www.expedia.ca/Hotel-Search?destination=Eastern+Panama%2C+Panama&regionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-03-11&d1=2026-03-11&endDate=2026-03-14&d2=2026-03-14&lodging=VACATION_HOME)

Houseboats

[](https://www.expedia.ca/Hotel-Search?destination=Eastern+Panama%2C+Panama&regionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-03-11&d1=2026-03-11&endDate=2026-03-14&d2=2026-03-14&lodging=HOUSE_BOAT)

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## Top Eastern Panama Hotel Reviews

![Ranchos de Chalia](https://images.trvl-media.com/lodging/106000000/105450000/105444000/105443903/5fee50e0_y.jpg)

### Ranchos de Chalia

10/10 Excellent

"Beautiful tranquility in nature, amazing staff"

[](https://expedia.ca/Puerto-Lindo-Hotels-Ranchos-De-Chalia.h105443903.Hotel-Information)

![HOTEL ISLA GRANDE ](https://images.trvl-media.com/lodging/120000000/119950000/119947200/119947185/9e6abf31_y.jpg)

### HOTEL ISLA GRANDE 

6/10 Okay

"Although I gave this hotel a medium rating I enjoyed myself. This is a rough almost close to camping hotel. I must have not seen the message about bringing soap wash clothes, hand towel, tissue actually everything. The water does not get cold and there was a party set up just outside the window lasting until 5 am. There are no amenities however the caribbean ocean is just outside the door. "

[](https://expedia.ca/Isla-Grande-Hotels-HOTEL-ISLA-GRANDE.h119947185.Hotel-Information)

![Hotel Cocotal](https://images.trvl-media.com/lodging/117000000/116790000/116790000/116789972/c828cfe9_y.jpg)

### Hotel Cocotal

10/10 Excellent

"It was old, quaint interesting, would recommend "

[](https://expedia.ca/La-Guaira-Hotels-Hotel-Cocotal.h116789972.Hotel-Information)

![Ordovician Beach Resort](https://images.trvl-media.com/lodging/104000000/103770000/103761600/103761591/4a052041_y.jpg)

### Ordovician Beach Resort

10/10 Excellent

"Amazing piece of Caribbean paradise! The staff went above and beyond to make us feel special."

[](https://expedia.ca/Ordovician-Beach-Resort.h103761591.Hotel-Information)

![Private Over the Water Cabin on San Blas Island](https://images.trvl-media.com/lodging/38000000/37720000/37715900/37715808/f17df0ed_y.jpg)

### Private Over the Water Cabin on San Blas Island

10/10 Excellent

"Very nice. And I liked the food "

[](https://expedia.ca/San-Blas-Islands-Hotels-Cabins-Over-The-Water-Wailidup-Island.h37715808.Hotel-Information)

![Ciel y Miel ](https://images.trvl-media.com/lodging/97000000/96740000/96735000/96734959/7979d8c3_y.jpg)

### Ciel y Miel 

10/10 Excellent

"All was good "

[](https://expedia.ca/Cacique-Hotels-Ciel-Y-Miel.h96734959.Hotel-Information)

![Discovery Gunayar](https://images.trvl-media.com/lodging/43000000/42120000/42113000/42112965/2cf1cd34_y.jpg)

### Discovery Gunayar

6/10 Okay

"Please fix my Expedia mobile app. It hasn’t worked for several days. The error message says the problem is at Expedia’s end. I have reported this issue by phone but nothing is being done."

[](https://expedia.ca/San-Blas-Islands-Hotels-Aridup-Island.h42112965.Hotel-Information)

## Find out more about Eastern Panama

## Eastern Panama Vacation Homes information

| Number of reviews | 1                 |
| ----------------- | ----------------- |
| Accommodation     | 35 Vacation Homes |
| Lowest Price      | CA $95            |
| Highest Price     | CA $1,372         |