Title: Book the Best Eastern Panama LUXURY Hotels - Upscale Hotels in Eastern Panama | Expedia.ca

 

[Eastern Panama Travel Guide](https://expedia.ca/Eastern-Panama.dx6246114)[Hotels in Eastern Panama](https://expedia.ca/Eastern-Panama-Hotels.d6246114.Travel-Guide-Hotels)[Vacation Rentals in Eastern Panama](https://expedia.ca/Eastern-Panama-Vacation-Rentals.d6246114.Travel-Guide-VacationRentals)[Flights to Eastern Panama](https://expedia.ca/Cheap-Flights-To-Eastern-Panama.d6246114.Travel-Guide-Flights)[Things to do in Eastern Panama](https://expedia.ca/Things-To-Do-In-Eastern-Panama.d6246114.Travel-Guide-Activities)[Eastern Panama Car Rentals](https://expedia.ca/Car-Rentals-In-Eastern-Panama.d6246114.Car-Rental-Guide)[Eastern Panama Vacation Packages](https://expedia.ca/Eastern-Panama.d6246114.Destination-Travel-Guides)

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# Find luxury hotels in Eastern Panama

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## Check availability on Eastern Panama Luxury Hotels

Tonight

[Nov 4 - Nov 5](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2025-11-04&endDate=2025-11-05&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Tomorrow

[Nov 5 - Nov 6](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2025-11-05&endDate=2025-11-06&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

This weekend

[Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2025-11-07&endDate=2025-11-09&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Next weekend

[Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2025-11-14&endDate=2025-11-16&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

## Top Eastern Panama Luxury Hotels

## Top Eastern Panama Hotel Reviews