Title: Book the Best BUSINESS Hotels in Eastern Panama in 2026 | Expedia.ca

[Eastern Panama Travel Guide](https://expedia.ca/Eastern-Panama.dx6246114)[Hotels in Eastern Panama](https://expedia.ca/Eastern-Panama-Hotels.d6246114.Travel-Guide-Hotels)[Vacation Rentals in Eastern Panama](https://expedia.ca/Eastern-Panama-Vacation-Rentals.d6246114.Travel-Guide-VacationRentals)[Flights to Eastern Panama](https://expedia.ca/Cheap-Flights-To-Eastern-Panama.d6246114.Travel-Guide-Flights)[Eastern Panama Car Rentals](https://expedia.ca/Car-Rentals-In-Eastern-Panama.d6246114.Car-Rental-Guide)[Eastern Panama Vacation Packages](https://expedia.ca/Eastern-Panama.d6246114.Destination-Travel-Guides)

![50 Shades of blue. Sailing through the San Blas Islands in Panama lets you experience  a pure paradise and crystal clear water. You can buy fresh fish and other seefood drirectly from local fishermen. If you want you can also play Robinson Crusoe on islands with literally only one palm tree. 
#BVSBlue](https://images.trvl-media.com/place/6246376/42fe0cae-c805-47d5-a705-ee119c68d58c.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Nico Barner

![](https://images.trvl-media.com/place/6246376/42fe0cae-c805-47d5-a705-ee119c68d58c.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check availability on Eastern Panama Business Hotels

Tonight

[Feb 5 - Feb 6](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2026-02-05&endDate=2026-02-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

Tomorrow

[Feb 6 - Feb 7](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2026-02-06&endDate=2026-02-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

This weekend

[Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

Next weekend

[Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

## Our top choices for Eastern Panama business-friendly hotels

![Luxury Suite](https://images.trvl-media.com/lodging/104000000/103770000/103761600/103761591/9a39b281.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/104000000/103770000/103761600/103761591/4a052041.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Suite](https://images.trvl-media.com/lodging/104000000/103770000/103761600/103761591/013d70fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Suite](https://images.trvl-media.com/lodging/104000000/103770000/103761600/103761591/c9b59f2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Ordovician Beach Resort

[](https://www.expedia.ca/Ordovician-Beach-Resort.h103761591.Hotel-Information)

Isla Grande

10/10

Exceptional

(7 reviews)

"The best service in Panama!!! We truly felt cared for in every detail — the team is attentive, warm, and genuinely professional. The food was outstanding: the chef is exceptional! Every dish reflected passion, quality, and pride. This hotel is located on a beautiful Caribbean island, surrounded by untouched nature, turquoise waters, and a truly magical atmosphere. What made it even more special was the silence and privacy — only the sound of the waves and the singing of birds!) A wonderful...

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Yevhen

CA $628

CA $697 total

includes taxes & fees

Feb 18 - Feb 19

[](https://www.expedia.ca/Ordovician-Beach-Resort.h103761591.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-19&endDate=2026-02-20&regionId=6246114&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true)

## Top Eastern Panama Hotel Reviews