Title: Panacea Vacation Packages & Trips 2026 from CA $1,644 | Expedia.ca [Panacea Travel Guide](https://expedia.ca/Panacea.dx3000431554)[Hotels in Panacea](https://expedia.ca/Panacea-Hotels.d3000431554.Travel-Guide-Hotels)[Vacation Rentals in Panacea](https://expedia.ca/Panacea-Vacation-Rentals.d3000431554.Travel-Guide-VacationRentals)[Panacea Car Rentals](https://expedia.ca/Car-Rentals-In-Panacea.d3000431554.Car-Rental-Guide) ![](https://images.trvl-media.com/place/3000431554/ef7510fd-7401-44b7-8add-0b033672a2ae.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Panacea Vacation Packages ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to CA $1,096 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place #### Your Panacea Vacation When you book a vacation package to Panacea, you can relax and enjoy your getaway knowing that all your travel plans have been worked out ahead of time. Discover the wonders of this city while based in a neighborhood like Ochlockonee Bay, which is great for nature. Up for some sightseeing? A trip to Panacea isn't complete without visiting [Mashes Sand Beach](https://www.expedia.ca/Mashes-Sand-Beach-Panacea.d553248635983994375.Vacation-Attraction), [Ochlockonee River State Park](https://www.expedia.ca/Ochlockonee-River-State-Park-Sopchoppy.d553248621532653556.Vacation-Attraction) and other popular attractions. Check out Expedia's wide range of travel options and start organizing your ideal vacation to Panacea now. ## Top Panacea Vacation Deals Price found within the past 48 hours. Click for updated prices. ![Staybridge Suites Tallahassee by IHG](https://images.trvl-media.com/lodging/2000000/1650000/1640200/1640108/98126d72_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Staybridge Suites Tallahassee by IHG CA $1,644 per person Apr 13 - Apr 20 found 1 day ago Roundtrip non-stop flight included Toronto (YTO) to Tallahassee (TLH) 9/10 Wonderful! (1,002 reviews) Room perfect and loved the outside courtyard@ Reviewed on Feb 2, 2026 ![La Familia Stay Inn](https://images.trvl-media.com/lodging/103000000/102480000/102479300/102479251/88cd6201_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### La Familia Stay Inn CA $2,611 per person Apr 13 - Apr 20 found 1 day ago Roundtrip non-stop flight included Toronto (YTO) to Tallahassee (TLH) 5.4/10 (20 reviews) Room was clean and staff was super nice. Really enjoyed my stay. Reviewed on Dec 16, 2025 ![DoubleTree by Hilton Hotel Tallahassee](https://images.trvl-media.com/lodging/1000000/30000/25100/25028/ce295c89_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### DoubleTree by Hilton Hotel Tallahassee Capitol Hill CA $1,889 per person Mar 25 - Mar 29 found 18 hours ago Roundtrip non-stop flight included Toronto (YTO) to Tallahassee (TLH) 7.4/10 Good! (1,004 reviews) Our double queen room was very cozy and the bed very comfortable. Staff members text us to see if we needed anything very kind staff. Had to ask for a garage pass to leave the garage. This was new for me. Reviewed on Feb 5, 2026 ![The Capitol Inn Tallahassee](https://images.trvl-media.com/lodging/101000000/100050000/100048000/100047935/9c6c9127_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Capitol Inn Tallahassee Midtown CA $2,414 per person Apr 13 - Apr 20 found 1 day ago Roundtrip non-stop flight included Toronto (YTO) to Tallahassee (TLH) 9.6/10 Exceptional! (153 reviews) This is a quaint inn- but the self check in is slightly complicated Reviewed on Jan 28, 2026 ![Hampton Inn & Suites Tallahassee Capitol - University](https://images.trvl-media.com/lodging/21000000/20870000/20869100/20869033/0961ece8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hampton Inn & Suites Tallahassee Capitol - University Railroad Square Art District CA $1,691 per person Apr 18 - Apr 25 found 21 hours ago Roundtrip non-stop flight included Vancouver (YVR) to Tallahassee (TLH) 9.2/10 Wonderful! (1,001 reviews) Clean room, friendly staff Reviewed on Feb 1, 2026 ## Ready to book your vacation to Panacea? Choose your dates ## Panacea Hotel Deals ![5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch](https://images.trvl-media.com/lodging/75000000/74830000/74824400/74824331/169d337b_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### 5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch Panacea FL 9.8/10 Exceptional! (80 reviews) The sunrise from this porch is breath taking. The house is well equipped and the the porch is simply amazing. Host was quick to respond and we will be renting this home again! Reviewed on Dec 19, 2025 [Get rates](https://expedia.ca/Hotel-Search?startDate=23%2F02%2F2026&endDate=24%2F02%2F2026&selected=74824331&PinnedHotelID=74824331&HadPinnedHotel=true®ionId=3000431554) [](https://expedia.ca/Hotel-Search?startDate=23%2F02%2F2026&endDate=24%2F02%2F2026&selected=74824331&PinnedHotelID=74824331&HadPinnedHotel=true®ionId=3000431554) ![7 Bedroom Beach House with POOL!! Gulf Front and Bay Front](https://images.trvl-media.com/lodging/20000000/19010000/19008300/19008298/df15e6fc_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### 7 Bedroom Beach House with POOL!! Gulf Front and Bay Front Alligator Point FL CA $957 CA $2,678 total Feb 10 - Feb 11 includes taxes & fees 10/10 Exceptional! (101 reviews) Our family had a great time. There was plenty of space for everyone to be alone when they needed it, but absolutely plenty of space to come together. Kitchen was fully stocked with all of the pots/pans/utensils needed. The house is right on the water with convenient access. The front yard was perfect ... Reviewed on Nov 10, 2025 [](https://expedia.ca/Hotel-Search?startDate=10%2F02%2F2026&endDate=11%2F02%2F2026&selected=19008298&PinnedHotelID=19008298&HadPinnedHotel=true®ionId=3000431554) ![The Panacea Motel](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/f641ddea_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Panacea Motel 1545 Coastal Hwy Panacea FL 9/10 Wonderful! (143 reviews) Room was clean and comfortable. We stayed during a record cold snap and the room stayed warm. Reviewed on Feb 6, 2026 [Get rates](https://expedia.ca/Hotel-Search?startDate=23%2F02%2F2026&endDate=24%2F02%2F2026&selected=95071987&PinnedHotelID=95071987&HadPinnedHotel=true®ionId=3000431554) [](https://expedia.ca/Hotel-Search?startDate=23%2F02%2F2026&endDate=24%2F02%2F2026&selected=95071987&PinnedHotelID=95071987&HadPinnedHotel=true®ionId=3000431554) [See all 509 properties in Panacea](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=10%2F02%2F2026&endDate=11%2F02%2F2026®ionId=3000431554) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ### Discover the most popular places to visit in Panacea #### USS Mohawk CGC Veterans Memorial Reef You can find out about the history of Panacea with a visit to USS Mohawk CGC Veterans Memorial Reef. Wander around the natural setting in this relaxing area, or simply enjoy its seafood restaurants. [](https://expedia.ca/USS-Mohawk-CGC-Veterans-Memorial-Reef-Panacea.d553248621561885546.Vacation-Attraction) ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app