Title: Book The Best Hotels in Panacea, FL for 2026 from CA $125 - Fully Refundable Options - Expedia.ca [Panacea Travel Guide](https://expedia.ca/Panacea.dx3000431554)[Vacation Rentals in Panacea](https://expedia.ca/Panacea-Vacation-Rentals.d3000431554.Travel-Guide-VacationRentals)[Panacea Car Rentals](https://expedia.ca/Car-Rentals-In-Panacea.d3000431554.Car-Rental-Guide)[Panacea Vacation Packages](https://expedia.ca/Panacea.d3000431554.Destination-Travel-Guides) ![Beautiful sunsets](https://images.trvl-media.com/place/3000431554/0e4e63ac-d470-468e-97e9-e5b3587cec19/sunset-beach-walk-waves-dog-friendly-coastline-pier-pilings.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Barbara Brogdon ![](https://images.trvl-media.com/place/3000431554/0e4e63ac-d470-468e-97e9-e5b3587cec19/sunset-beach-walk-waves-dog-friendly-coastline-pier-pilings.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Panacea Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2026-02-04&d1=2026-02-04&endDate=2026-02-06&d2=2026-02-06&amenities=PETS) Ocean view [](https://www.expedia.ca/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2026-02-04&d1=2026-02-04&endDate=2026-02-06&d2=2026-02-06&amenities=OCEAN_VIEW) Pool [](https://www.expedia.ca/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2026-02-04&d1=2026-02-04&endDate=2026-02-06&d2=2026-02-06&amenities=POOL) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2026-02-04&d1=2026-02-04&endDate=2026-02-06&d2=2026-02-06&travelerType=family_friendly) Cottage [](https://www.expedia.ca/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2026-02-04&d1=2026-02-04&endDate=2026-02-06&d2=2026-02-06&lodging=COTTAGE) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2026-02-04&d1=2026-02-04&endDate=2026-02-06&d2=2026-02-06&lodging=APARTMENT) Condo [](https://www.expedia.ca/Hotel-Search?destination=Panacea%2C+Florida%2C+United+States+of+America®ionId=3000431554&latLong=30.02912%2C-84.398613&adults=2&startDate=2026-02-04&d1=2026-02-04&endDate=2026-02-06&d2=2026-02-06&lodging=CONDO) ## Check prices for these dates Tonight [Jan 21 - Jan 22](https://www.expedia.ca/Hotel-Search?regionId=3000431554&startDate=2026-01-21&endDate=2026-01-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 22 - Jan 23](https://www.expedia.ca/Hotel-Search?regionId=3000431554&startDate=2026-01-22&endDate=2026-01-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=3000431554&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=3000431554&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Panacea hotels ![Comfort Studio | Terrace/patio](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/7ddc9d09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Cottage | Private kitchen](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/b404a7b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Cottage | Private kitchen](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/df64fc22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/f641ddea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Panacea Motel [](https://www.expedia.ca/Panacea-Hotels-The-Panacea-Motel.h95071987.Hotel-Information) Panacea 9.0/10 Wonderful (142 reviews) "The room was clean. the ac was great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elliot CA $148 CA $165 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Panacea-Hotels-The-Panacea-Motel.h95071987.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/122000000/121770000/121767100/121767092/a22e2ae9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/122000000/121770000/121767100/121767092/551331a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/122000000/121770000/121767100/121767092/d1920fdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/122000000/121770000/121767100/121767092/6048f183.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Old Carrabelle Hotel [](https://www.expedia.ca/Carrabelle-Hotels-The-Old-Carrabelle-Hotel.h121767092.Hotel-Information) Carrabelle 9.0/10 Wonderful (2 reviews) "Clean room, older property but had old Florida charm." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deirdre CA $118 CA $131 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Carrabelle-Hotels-The-Old-Carrabelle-Hotel.h121767092.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/6000000/5420000/5411800/5411745/3e99d756.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/6000000/5420000/5411800/5411745/aa318832.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/6000000/5420000/5411800/5411745/5b60f16d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/6000000/5420000/5411800/5411745/83d33573.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lodge at Wakulla Springs [](https://www.expedia.ca/Tallahassee-Hotels-The-Lodge-At-Wakulla-Springs.h5411745.Hotel-Information) Crawfordville 9.4/10 Exceptional (1,007 reviews) "Great old Florida Lodge Beautiful grounds and springs" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ed [](https://www.expedia.ca/Tallahassee-Hotels-The-Lodge-At-Wakulla-Springs.h5411745.Hotel-Information) ![Daily cooked-to-order breakfast for a fee](https://images.trvl-media.com/lodging/24000000/23970000/23962800/23962755/9a81e303.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/24000000/23970000/23962800/23962755/a49c599c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/24000000/23970000/23962800/23962755/b57f7efd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/24000000/23970000/23962800/23962755/d6fe4fb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### St James Bay Golf & Pickleball Resort [](https://www.expedia.ca/Carrabelle-Hotels-St-James-Bay-Golf-Club.h23962755.Hotel-Information) Carrabelle 9.0/10 Wonderful (375 reviews) "Great size room and good food" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Edi CA $220 CA $243 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Carrabelle-Hotels-St-James-Bay-Golf-Club.h23962755.Hotel-Information) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/46000000/45040000/45034100/45034076/c81957b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, free toiletries, towels, soap](https://images.trvl-media.com/lodging/46000000/45040000/45034100/45034076/a2c8b110.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/46000000/45040000/45034100/45034076/9928e089.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/46000000/45040000/45034100/45034076/5a6de88c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Franklin Inn [](https://www.expedia.ca/Carrabelle-Hotels-Franklin-Inn.h45034076.Hotel-Information) Carrabelle 7.8/10 Good (457 reviews) "JJ was great great location clean room comfortable bed and good value. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Crystal CA $113 CA $125 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Carrabelle-Hotels-Franklin-Inn.h45034076.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/104000000/103250000/103241100/103241082/049ab2fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/104000000/103250000/103241100/103241082/b073fdcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/104000000/103250000/103241100/103241082/b5016fe6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Game room](https://images.trvl-media.com/lodging/104000000/103250000/103241100/103241082/413778f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Moorings Hotel and Marina [](https://www.expedia.ca/Carrabelle-Hotels-The-Moorings-Hotel-And-Marina.h103241082.Hotel-Information) Carrabelle 8.4/10 Very good (39 reviews) "Hotel was really nice and convenient to everything we wanted to do in the area. Very quiet and peaceful. Bed was a little uncomfortable, but that's a personal preference thing and I won't fault them for that. Really nice staff and easy check in and check out. Would definitely return!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cheryl CA $181 CA $201 total includes taxes & fees Jan 29 - Jan 30 [](https://www.expedia.ca/Carrabelle-Hotels-The-Moorings-Hotel-And-Marina.h103241082.Hotel-Information) ![Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave](https://images.trvl-media.com/lodging/2000000/1740000/1730200/1730125/a52a90f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1740000/1730200/1730125/25adabe5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1740000/1730200/1730125/ab700b1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/2000000/1740000/1730200/1730125/859a993c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Wakulla Inn & Suites [](https://www.expedia.ca/Tallahassee-Hotels-Best-Western-Wakulla-Inn-Suites.h1730125.Hotel-Information) Crawfordville 8.8/10 Excellent (951 reviews) "Breakfast last was super nice and helpful. Room was clean and comfortable. Only issue was when we returned after the day out room service cleaned the room but left out room door open. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Wendy CA $154 CA $172 total includes taxes & fees Feb 3 - Feb 4 [](https://www.expedia.ca/Tallahassee-Hotels-Best-Western-Wakulla-Inn-Suites.h1730125.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1540000/1533000/1532906/93dee934.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/2000000/1540000/1533000/1532906/4f65d9b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/2000000/1540000/1533000/1532906/4b7008a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1540000/1533000/1532906/w1910h1085x0y0-4ad0d4a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wildwood Inn [](https://www.expedia.ca/Crawfordville-Hotels-Wildwood-Inn.h1532906.Hotel-Information) Crawfordville 8.6/10 Excellent (1,001 reviews) "Enjoyed our stay and would definitely stay again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Corey CA $151 CA $174 total includes taxes & fees Feb 4 - Feb 5 [](https://www.expedia.ca/Crawfordville-Hotels-Wildwood-Inn.h1532906.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-04&endDate=2026-02-05®ionId=3000431554&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FPanacea-Hotels.d3000431554.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FPanacea-Hotels.d3000431554.Travel-Guide-Hotels) ## Learn more about Panacea Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails. [See all hotels in Panacea](https://www.expedia.ca/Hotel-Search?startDate=2026-02-04&endDate=2026-02-05&adults=2®ionId=3000431554) ![Sunset over a lake at Panacea, northern Florida, USA | NONE |](https://images.trvl-media.com/place/3000431554/82102cb8-9bdc-4f33-be26-bab6063d4ccd.jpg?impolicy=fcrop&w=267&h=399&p=1&q=high) ### Stay near popular Panacea attractions [](https://expedia.ca/Alligator-Point-Beach-Hotels.0-l553248635983992302-0.Travel-Guide-Filter-Hotels) #### Alligator Point Beach Why not spend a lazy afternoon at Alligator Point Beach during your trip to Alligator Point? [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635983992302) [](https://expedia.ca/Bald-Point-State-Park-Hotels.0-l553248621532654045-0.Travel-Guide-Filter-Hotels) #### Bald Point State Park You can take time to visit Bald Point State Park during your travels to Alligator Point. Stroll along the beaches in this relaxing area, or seek out the fishing spots. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532654045) [](https://expedia.ca/Mashes-Sand-Beach-Hotels.0-l553248635983994375-0.Travel-Guide-Filter-Hotels) #### Mashes Sand Beach Why not spend a lazy afternoon at Mashes Sand Beach during your trip to Panacea? Amble around this relaxing area's beaches, or seek out the fishing spots. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635983994375) [](https://expedia.ca/USS-Mohawk-CGC-Veterans-Memorial-Reef-Hotels.0-l553248621561885546-0.Travel-Guide-Filter-Hotels) #### USS Mohawk CGC Veterans Memorial Reef You can find out about the history of Panacea with a visit to USS Mohawk CGC Veterans Memorial Reef. Wander around the natural setting in this relaxing area, or simply enjoy its seafood restaurants. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621561885546) ## More cheap stays in Panacea ![Franklin Inn](https://images.trvl-media.com/lodging/46000000/45040000/45034100/45034076/4470f88b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Franklin Inn 1589 US-98 Carrabelle FL CA $113 CA $125 total Jan 22 - Jan 23 includes taxes & fees 7.8/10 Good! (457 reviews) [](https://expedia.ca/Carrabelle-Hotels-Franklin-Inn.h45034076.Hotel-Information) ![The Panacea Motel](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/f641ddea_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Panacea Motel 1545 Coastal Hwy Panacea FL CA $148 CA $165 total Jan 22 - Jan 23 includes taxes & fees 9/10 Wonderful! (142 reviews) [](https://expedia.ca/Panacea-Hotels-The-Panacea-Motel.h95071987.Hotel-Information) ![Best Western Wakulla Inn & Suites](https://images.trvl-media.com/lodging/2000000/1740000/1730200/1730125/9ff25f41_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Wakulla Inn & Suites 3292 Coastal Hwy 98 Crawfordville FL CA $154 CA $172 total Feb 3 - Feb 4 includes taxes & fees 8.6/10 Excellent! (950 reviews) [](https://expedia.ca/Tallahassee-Hotels-Best-Western-Wakulla-Inn-Suites.h1730125.Hotel-Information) ![The Moorings Hotel and Marina ](https://images.trvl-media.com/lodging/104000000/103250000/103241100/103241082/f34571a2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Moorings Hotel and Marina 1000 Hwy 98 Carrabelle FL CA $181 CA $201 total Jan 29 - Jan 30 includes taxes & fees 8.4/10 Very Good! (39 reviews) [](https://expedia.ca/Carrabelle-Hotels-The-Moorings-Hotel-And-Marina.h103241082.Hotel-Information) ![Canal-front home at Shell Point. Relax. Fish. Explore. Swim. Amazing Sunsets!](https://images.trvl-media.com/lodging/122000000/121250000/121245500/121245426/1c35e8cb_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Canal-front home at Shell Point. Relax. Fish. Explore. Swim. Amazing Sunsets! Crawfordville FL CA $214 CA $486 total Jan 25 - Jan 26 includes taxes & fees 10/10 Exceptional! (4 reviews) [](https://expedia.ca/Crawfordville-Hotels-Shell-Point-Canal-Front-Home-Come-Enjoy-A-Carefree-Comfortable-Stay-In-Paradise.h121245426.Hotel-Information) ![Pet friendly Kayak with the manatees](https://images.trvl-media.com/lodging/109000000/108410000/108408700/108408667/dad3a8f0_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pet friendly Kayak with the manatees Crawfordville FL [Get rates](https://expedia.ca/Hotel-Search?startDate=04%2F02%2F2026&endDate=05%2F02%2F2026&selected=108408667&PinnedHotelID=108408667&HadPinnedHotel=true®ionId=3000431554) 9.8/10 Exceptional! (47 reviews) [](https://expedia.ca/Crawfordville-Hotels-Charming-3-Bedroom-House-With-AC-And-WiFi-In-Crawfordville.h108408667.Hotel-Information) ## Hotels in Panacea with star-rating ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 44 properties [](https://expedia.ca/3Star-Panacea-Hotels.s30-0-d3000431554.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 60 properties [](https://expedia.ca/2Star-Panacea-Hotels.s20-0-d3000431554.Travel-Guide-Filter-Hotels) ## Find out more about Panacea ### Top reasons to visit Panacea - **Scenic Beaches:** Panacea boasts beautiful, inviting beaches perfect for relaxation and fun in the sun. - **Outdoor Adventures:** Enjoy recreational activities in nearby national and state parks, ideal for nature lovers. - **Charming Neighborhoods:** Explore family-friendly areas with friendly locals that enhance the coastal experience. - **Diverse Accommodations:** Find a range of pet-friendly lodging options, from cozy guesthouses to comfortable motels. - **Ideal Base for Exploration:** Panacea's central location makes it a great starting point for discovering nearby attractions. ### Find great hotels near Panacea Discover the charm of Panacea, Florida, where a variety of lodging options await you. Whether you’re looking for a cozy guesthouse or a comfortable motel, you’ll find pet-friendly accommodations that cater to your adventure and business needs. Explore top hotels and vacation homes that provide a welcoming atmosphere, ensuring a memorable stay in this picturesque coastal town. - **[Hyatt House Tallahassee Capitol – University: ](https://www.expedia.ca/Tallahassee-Hotels-Hyatt-House-Tallahassee-Capitol-Univer.h58811398.Hotel-Information)** This 3-star hotel offers a welcoming atmosphere tailored for both family and business travellers. Located 46.7km from Panacea, it features a range of amenities that include a Business Centre and accessible meeting rooms, making it perfect for professionals on the go. Families will appreciate the thoughtful touches such as cribs for infants and safety window guards for children. Additionally, the hotel is pet-friendly, allowing you to bring your furry companions along for the adventure. With its blend of comfort and practicality, it's an excellent choice for a well-rounded vacation experience. - **[Best Western Wakulla Inn & Suites: ](https://www.expedia.ca/Tallahassee-Hotels-Best-Western-Wakulla-Inn-Suites.h1730125.Hotel-Information)** Situated only 9.7km from Panacea, this hotel is ideal for those seeking adventure alongside business amenities. With a 24-hour Business Centre and multiple meeting rooms, it caters to corporate needs while also providing a playground for outdoor enthusiasts. Guests can embark on nearby adventures like hiking, snorkeling, or sailing. Whether you're winding down after a day of meetings or seeking thrills in nature, the Best Western Wakulla Inn & Suites offers a perfect blend of professional and recreational opportunities. - **[Magnuson Hotel Wildwood Inn: ](https://www.expedia.ca/Crawfordville-Hotels-Wildwood-Inn.h1532906.Hotel-Information)** Located 11.3km from Panacea, this 3-star hotel combines adventure, business facilities, and a pet-friendly environment. Its business amenities include accessible meeting rooms and a Business Centre, making it a suitable option for travelling professionals. Guests can indulge in various outdoor activities such as mountain biking, fishing, and sailing nearby. The hotel also welcomes pets, which makes it a great choice for those who want to bring their four-legged friends along. It's a versatile option for visitors looking for both work and play. ### Where to stay in Panacea Panacea, Florida, offers a delightful blend of serene beaches and outdoor adventures, making it an ideal spot for a relaxing getaway. Just a short stroll from the coast, you'll find charming neighborhoods with a family-friendly atmosphere and friendly locals. Explore the stunning shoreline, indulge in romantic escapes, and soak up the coastal vibe that defines this picturesque region. With its central location, Panacea serves as a perfect base for discovering nearby attractions and creating unforgettable memories. - **[Alligator Point: ](https://www.expedia.ca/Alligator-Point-Hotels.d553248635975849030.Travel-Guide-Hotels)** Nestled along the Gulf Coast, Alligator Point is a charming village near Panacea known for its tranquil beaches and outdoor experiences. The village offers a serene atmosphere, especially from May to July when visitor numbers peak. Here, you can indulge in activities such as golfing, or relax at the local resorts. The nearby beach and national state park provide stunning scenery, while the wetlands serve as a habitat for diverse wildlife, making it perfect for nature enthusiasts and photographers alike. - **[Saint Teresa: ](https://www.expedia.ca/Saint-Teresa-Hotels.d3000432006.Travel-Guide-Hotels)** Located just a stone's throw away from Panacea, Saint Teresa is a delightful village that attracts visitors seeking a peaceful retreat. With peak travel times in March and June to July, this area is well-loved for its beautiful beaches and outdoor recreational opportunities. Golfing enthusiasts will find several courses nearby, while the surrounding national state park and wetlands offer ample chances for exploration and relaxation. Saint Teresa is an ideal spot to enjoy the natural beauty of Florida’s coast. - **[Ochlockonee Bay: ](https://www.expedia.ca/Ochlockonee-Bay-Hotels.d553248635975855809.Travel-Guide-Hotels)** Ochlockonee Bay, another picturesque village near Panacea, is a haven for those who crave adventure and scenic views. Travellers flock here from May to July, drawn by its outdoor activities and stunning landscapes. The village features a range of recreational areas and resorts, perfect for unwinding after a day of exploration. With its proximity to beautiful beaches and the national state park, Ochlockonee Bay offers a unique blend of relaxation and adventure, making it a must-visit on your Florida getaway. ### Things to do in and around Panacea Panacea, Florida, offers a delightful getaway for those seeking beach and outdoor adventures amidst beautiful scenery. Visitors can explore various attractions, including recreational areas and educational spots, while enjoying the comforts of local resorts. Whether you're looking to relax by the beach or engage in outdoor activities, Panacea provides a perfect blend of leisure and exploration, making it an ideal destination for a memorable vacation. **Shopping** In Panacea, the local shopping includes the [Flea Market Tallahassee](https://www.expedia.ca/Flea-Market-Tallahassee-Hotels.0-l553248621587242546-0.Travel-Guide-Filter-Hotels), 40.2km away, offering a vibrant atmosphere. If you're up for a drive, check out the [Tallahassee Downtown Market](https://www.expedia.ca/Tallahassee-Downtown-Market-Hotels.0-l553248621533122360-0.Travel-Guide-Filter-Hotels) and [Governor's Square Mall](https://www.expedia.ca/Governors-Square-Mall-Hotels.0-l6127864-0.Travel-Guide-Filter-Hotels), both 46.7km away, for a mix of entertainment and unique finds. **Recreation** Experience the [St. James Bay Golf Club](https://www.expedia.ca/St-James-Bay-Golf-Club-Hotels.0-l553248621532653555-0.Travel-Guide-Filter-Hotels), where you can enjoy a round of golf amidst beautiful landscapes just 20.9km from Panacea. For relaxation, Woolley Park and Morrison Hammock Scenic Area, both nearby, offer serene environments perfect for unwinding and connecting with nature. **Adventure** The [Tallahassee-Saint Marks Historic Railroad Trail State Park](https://www.expedia.ca/Tallahassee-Saint-Marks-Historic-Railroad-Trail-State-Park-Hotels.0-l553248621563220102-0.Travel-Guide-Filter-Hotels), located 43.5km from Panacea, invites you to hike through picturesque landscapes. Similarly, the [Tallahassee-St. Marks Historic Railroad State Trail](https://www.expedia.ca/Tallahassee-St-Marks-Historic-Railroad-State-Trail-Hotels.0-l553248621532654100-0.Travel-Guide-Filter-Hotels), 46.7km away, offers stunning scenery. Experience the serene beauty of the [Saint Marks Trail](https://www.expedia.ca/Saint-Marks-Trail-Hotels.0-l553248621532654052-0.Travel-Guide-Filter-Hotels), situated 45.1km from Panacea. **Nightlife** In Panacea, [Theatre Tallahassee](https://www.expedia.ca/Theatre-Tallahassee-Hotels.0-l553248621561885522-0.Travel-Guide-Filter-Hotels) is a captivating destination for nightlife. Located 49.9km away, it offers a blend of culture and entertainment, perfect for a romantic evening or a family outing. Enjoy a memorable performance in a welcoming atmosphere that highlights the local arts scene. \*Distances are measured in a straight line; actual driving distances may vary depending on the route. ### Booking tips and Expedia advantages for Panacea To save money during your visit to Panacea, Florida, consider travelling in July or between December and January when prices are lower. Aim to book your stay for a Monday, as it offers the best rates compared to Fridays. Use Expedia's search tool to find budget-friendly accommodations by arranging prices from lowest to highest. Additionally, consider booking a package that combines your hotel with flights and activities for further savings. Take advantage of the area's free activities and explore local sights on foot or via affordable public transport to keep costs down. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in Panacea are July and December to January, where the prices are slightly lower. This is in comparison to May and September to October, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Panacea is Monday. The most expensive day to stay in Panacea is Friday. - **Find cheap hotels on Expedia:** Utilize Expedia's search tool to refine your options based on your budget, preferred location, and desired type of accommodation. To find the best prices and deals, simply arrange the price filter from lowest to highest. - **Consider bundling your trip:** You can save money by combining your Panacea hotel reservation with your flights and activities through an Expedia package. ### Find the best attractions in Panacea Panacea, Florida, is an ideal destination for beach lovers and outdoor enthusiasts seeking scenic beauty. Visitors can explore local attractions such as Panacea Park and enjoy the nearby national and state parks, as well as stunning islands. With its inviting beaches and natural landscapes, Panacea offers a perfect getaway for those looking to unwind in nature and experience the great outdoors. - **[Alligator Point Beach: ](https://www.expedia.ca/Alligator-Point-Beach-Hotels.0-l553248635983992302-0.Travel-Guide-Filter-Hotels)** Experience the laid-back beach vibes at Alligator Point Beach, where you can relax on soft sands, swim in crystal-clear waters, and enjoy stunning sunsets over the Gulf of Mexico. - **[Bald Point State Park: ](https://www.expedia.ca/Bald-Point-State-Park-Hotels.0-l553248621532654045-0.Travel-Guide-Filter-Hotels)** Embrace adventure and breathtaking scenery at Bald Point State Park. Explore winding trails, spot diverse wildlife, and take in panoramic views of the coastline, perfect for hiking and birdwatching enthusiasts. - **[USS Mohawk CGC Veterans Memorial Reef: ](https://www.expedia.ca/USS-Mohawk-CGC-Veterans-Memorial-Reef-Hotels.0-l553248621561885546-0.Travel-Guide-Filter-Hotels)** Dive into history at the USS Mohawk CGC Veterans Memorial Reef. This unique underwater site honours veterans while offering an incredible opportunity for snorkelling and diving among vibrant marine life. ### Best time to go to Panacea The best time to visit Panacea can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Panacea falls in July and August. August has average visitor numbers and mostly sunny weather. The coolest average temperature in Panacea falls in January, visitor numbers are average and weather is mostly sunny with light rain. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | ---------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------- | | January | 53.6°F (12.0°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | February | 57.6°F (14.2°C) | Light Rain | Mostly Sunny | Average | Average | | March | 62.4°F (16.9°C) | Light Rain | Mostly Sunny | Average | Average | | April | 68.2°F (20.1°C) | Light Rain | Mostly Sunny | Moderately High | Average | | May | 74.8°F (23.8°C) | Light Rain | Mostly Sunny | Average | Slightly High | | June | 80.4°F (26.9°C) | Moderate Rain | Mostly Sunny | Moderately High | Average | | July | 81.7°F (27.6°C) | Moderate Rain | Mostly Sunny | Moderately High | Slightly Low | | August | 81.7°F (27.6°C) | Moderate Rain | Mostly Sunny | Average | Average | | September | 78.4°F (25.8°C) | Light Rain | Mostly Sunny | Average | Slightly High | | October | 71.1°F (21.7°C) | Light Rain | Mostly Sunny | Moderately Low | Slightly High | | November | 61.9°F (16.6°C) | Light Rain | Mostly Sunny | Moderately Low | Average | | December | 57.6°F (14.2°C) | Light Rain | Mostly Sunny | Moderately Low | Slightly Low | ### The nearest major airports for your trip to Panacea If you're planning a visit to Panacea, Florida, the nearest major airport is Tallahassee International Airport ([TLH](https://www.expedia.ca/Tallahassee-Intl-Airport-Hotels.0-aTLH-0.Travel-Guide-Filter-Hotels)), situated 41.8km away. For accommodation, consider the [DoubleTree by Hilton Hotel Tallahassee](https://www.expedia.ca/Tallahassee-Hotels-DoubleTree-By-Hilton-Hotel-Tallahassee.h25028.Hotel-Information) and [Hotel Duval](https://www.expedia.ca/Tallahassee-Hotels-Hotel-Duval.h9568.Hotel-Information), both 8.0km from TLH, offering convenient airport shuttle services. Another option is the Hotel Indigo Tallahassee - Collegetown, located 6.4km from the airport. All these hotels provide easy access to the airport, ensuring a seamless travel experience during your stay in Panacea. ## Recent reviews of Panacea hotels ![The Panacea Motel](https://images.trvl-media.com/lodging/96000000/95080000/95072000/95071987/f641ddea_y.jpg) ### The Panacea Motel 5/5 Excellent "The room was clean. the ac was great" A verified traveller stayed at The Panacea Motel Posted 5 days ago [](https://expedia.ca/Panacea-Hotels-The-Panacea-Motel.h95071987.Hotel-Information) ![Happy Shack BEACH & BAY! Kayak, paddle boards, tiki hut, firepit, grille, wifi](https://images.trvl-media.com/lodging/27000000/26600000/26599500/26599452/09f71ac2_y.jpg) ### Happy Shack BEACH & BAY! Kayak, paddle boards, tiki hut, firepit, grille, wifi 5/5 Excellent "Excellent amenities. Stunning location. Clean. Great place to chill and enjoy nature. Can't wait to return." A verified traveller stayed at Happy Shack BEACH & BAY! Kayak, paddle boards, tiki hut, firepit, grille, wifi Posted 6 days ago [](https://expedia.ca/Panacea-Hotels-Happy-Shack-BEACH-BAY-Kayak.h26599452.Hotel-Information) ![Oceanfront on a Private Beach-Hot Tub-Beautifully Remodeled-Dog Friendly Beach](https://images.trvl-media.com/lodging/99000000/98480000/98476700/98476634/9da6b804_y.jpg) ### Oceanfront on a Private Beach-Hot Tub-Beautifully Remodeled-Dog Friendly Beach 5/5 Excellent "Melynda is an amazing host. Melynda's home is what all other vacation rentals should aspire to become. The house is spotless and well stocked. The amenities are amazing. The beds are comfortable and you will miss the shower when you get home. The location is fantastic. The neighbor is very kind. The beach is quiet. We walked for miles every day and collected huge shells. Our dogs loved the walks and the dolphins put on quite a show. The sunrises and sunsets are phenomenal and I hope everyone can experience a foggy day while at Alligator point...pure magic. We cooked from scratch meals every day and had literally everything we needed. We look forward to returning to this home. Melynda goes above and beyond to care for her guests and her home. " A verified traveller stayed at Oceanfront on a Private Beach-Hot Tub-Beautifully Remodeled-Dog Friendly Beach Posted 8 days ago [](https://expedia.ca/Panacea-Hotels-Oceanfront-Private-Beach-Beautifully-Decorated-Remodeled-On-121-Acres.h98476634.Hotel-Information) ![PRIVATE LUXURY BEACHFRONT HOME!](https://images.trvl-media.com/lodging/56000000/55370000/55361200/55361115/c761bdff_y.jpg) ### PRIVATE LUXURY BEACHFRONT HOME! 5/5 Excellent "This property had great spaces" A verified traveller stayed at PRIVATE LUXURY BEACHFRONT HOME! Posted 12 days ago [](https://expedia.ca/Panacea-Hotels-NEW-5-Bedroom-5-Bathroom-Beachfront-Home-With-Views-From-Every-Room.h55361115.Hotel-Information) ![ Charming Alligator Point "Old Florida” Beach Cottage ](https://images.trvl-media.com/lodging/35000000/34590000/34581200/34581134/2c943c28_y.jpg) ### Charming Alligator Point "Old Florida” Beach Cottage 5/5 Excellent "The cottage is perfectly clean and furnished with many cozy touches as well as beautiful art. Wendy is one of the most friendly and welcoming hosts of any place where we've visited. What we enjoy the most about the house is the location in a quiet, non-crowded area away from traffic, with only the birds and sea life surrounding us. The view of sunrise and sunset from the screened porch is beyond compare!" A verified traveller stayed at Charming Alligator Point "Old Florida” Beach Cottage Posted 2 weeks ago [](https://expedia.ca/Panacea-Hotels-Charming-Alligator-Point-Old-Florida-Beach-Cottage.h34581134.Hotel-Information) ![Ochlockonee Bay Waterfront Home 200 ft pier 1st floor over looking the bay](https://images.trvl-media.com/lodging/107000000/106380000/106377800/106377762/82e3e83b_y.jpg) ### Ochlockonee Bay Waterfront Home 200 ft pier 1st floor over looking the bay 5/5 Excellent "Vert nice house, very clean and confortable , perfect for relax and fish on the dock, amazing fish, really nice host....ty nancy " A verified traveller stayed at Ochlockonee Bay Waterfront Home 200 ft pier 1st floor over looking the bay Posted 3 weeks ago [](https://expedia.ca/Panacea-Hotels-Waterfront-Home-200-Ft-Pier1st-Floor.h106377762.Hotel-Information) ![The Best Beach-Front House “Get-A-Way” in Florida](https://images.trvl-media.com/lodging/69000000/68410000/68408000/68407918/0a19b2c0_y.jpg) ### The Best Beach-Front House “Get-A-Way” in Florida 5/5 Excellent "Everything we needed!" A verified traveller stayed at The Best Beach-Front House “Get-A-Way” in Florida Posted 3 weeks ago [](https://expedia.ca/Panacea-Hotels-The-Best-Beach-Front-House-Get-A-Way-In-Florida.h68407918.Hotel-Information) ![NEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property!](https://images.trvl-media.com/lodging/119000000/118720000/118717600/118717563/eedfea7d_y.jpg) ### NEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property! 5/5 Excellent "Location is perfect! Woke up to a beautiful sunrise every morning. " A verified traveller stayed at NEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property! Posted 3 weeks ago [](https://expedia.ca/Panacea-Hotels-Spacious-4BR45BA-Bald-Point-Beach-Home-Perfect-For-Families-Groups.h118717563.Hotel-Information) !["Shifting Sands" Private Beach Front 3 Bd, 2 Bath, sleeps 8 ](https://images.trvl-media.com/lodging/64000000/63080000/63079600/63079590/63c77c39_y.jpg) ### "Shifting Sands" Private Beach Front 3 Bd, 2 Bath, sleeps 8 5/5 Excellent "Wow- the view from this house is glorious! Everything about it is just beautiful. My little 84 year old mom had the time of her life and my brothers and her grandchildren are so grateful.Thank you." A verified traveller stayed at "Shifting Sands" Private Beach Front 3 Bd, 2 Bath, sleeps 8 Posted 1 month ago [](https://expedia.ca/Panacea-Hotels-Shifting-Sands-Private-Beach-Front-3-Bd.h63079590.Hotel-Information) ## Frequently asked questions ### What are the best budget hotels in Panacea? ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Panacea hotel booking with Expedia? ### How much is the nightly rate at a Panacea hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - More ways to book - [2 Star Hotels in Carrabelle ](https://www.expedia.ca/2Star-Carrabelle-Hotels.s20-0-d86458.Travel-Guide-Filter-Hotels) - [Farmstay in Alligator Point ](https://www.expedia.ca/Alligator-Point-Agritourism.d553248635975849030-aaAgritourism.Travel-Guide-Accommodation) - [Beach Hotel Hotels in Alligator Point ](https://www.expedia.ca/Alligator-Point-Hotels-Beach-Hotel.0-0-d553248635975849030-tBeachHotel.Travel-Guide-Filter-Hotels) - 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