Title: Visit Lake Nona Medical City: Best of Lake Nona Medical City, Orlando Travel 2026 | Expedia Tourism - Expedia.ca [Hotels in Lake Nona Medical City](https://expedia.ca/Lake-Nona-Medical-City-Orlando-Hotels.0-n6197057-0.Travel-Guide-Filter-Hotels)[Flights to Orlando](https://expedia.ca/Cheap-Flights-To-Orlando.d178294.Travel-Guide-Flights)[Things to do in Orlando](https://expedia.ca/Things-To-Do-In-Orlando.d178294.Travel-Guide-Activities)[Lake Nona Medical City Car Rentals](https://expedia.ca/Car-Rentals-In-Lake-Nona-Medical-City.d6197057.Car-Rental-Guide)[Lake Nona Medical City Vacations](https://expedia.ca/Lake-Nona-Medical-City.d6197057.Destination-Travel-Guides) # Lake Nona Medical City ## Orlando ## Visit Lake Nona Medical City Things to do Hotels Where to stay [Orlando travel guide](https://expedia.ca/Orlando.dx178294) --- ### Popular places to visit ![Walt Disney World® Resort](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/555000/555500-walt-disney-worldr-resort.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Walt Disney World® Resort 4.5/5(226 reviews) Walt Disney World® Resort is part of Orlando. It makes up part of bustling metropolis that is home to 240,000 inhabitants. Walt Disney World® Resort is approximately 15 miles (24 kilometers) from Orlando’s city center. If you are flying in, Walt Disney World® Resort is approximately 15 miles (24 kilometers) from Orlando International Airport. [](https://expedia.ca/Walt-Disney-World-Resort-Orlando.d6034120.Vacation-Attraction) ![Universal Studios Florida](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/492000/492960-universal-studios-orlando.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Universal Studios Florida 4.5/5(988 reviews) Movie sets and thrill rides combine to create this internationally acclaimed theme park. [](https://expedia.ca/Universal-Studios-Florida-Florida-Center.d6049239.Vacation-Attraction) ![Universal Studios Orlando which includes street scenes, a city and rides](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22562-Universal-Studios-Orlando.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Universal Orlando Resort 4.5/5(399 reviews) Make your Florida vacation one to remember with a stay at this hotel and theme park complex. [](https://expedia.ca/Universal-Orlando-Resort-Florida-Center.d6347698.Vacation-Attraction) ![Disney Springs™](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/438000/438595-Disney-Springsr.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Disney Springs™ 4.5/5(1,107 reviews) You can search for that perfect souvenir when you visit Disney Springs™, a favorite shopping spot in Lake Buena Vista. Experience the acclaimed theater scene and entertainment choices in this family-friendly area. [](https://expedia.ca/Disney-SpringsTM-Orlando.d502131.Vacation-Attraction) ![Magic Kingdom® Park showing rides](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/35000/35707-Magic-Kingdom.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Magic Kingdom® Park 4.5/5(916 reviews) One of the most famous theme parks in the world offers a land of fun and fantasy at the foot of a fairytale castle. [](https://expedia.ca/Magic-Kingdom-Park-Bay-Lake.d6123797.Vacation-Attraction) ![Orange County Convention Center](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/52000/52188-Orange-County-Convention-Centre.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Orange County Convention Center 4.5/5(124 reviews) Florida's principal convention center is a large and stunning glass and metal building that hosts national and international trade shows and public events. [](https://expedia.ca/Orange-County-Convention-Center-International-Drive-District.d6034972.Vacation-Attraction) ### Things to do ![Aquatica Orlando](https://mediaim.expedia.com/localexpert/407892/33b09fce-abbf-446b-bce5-738d4c15128d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Aquatica Orlando CA $73 per traveller **84%** of travellers recommend [](https://expedia.ca/things-to-do/aquatica-orlando.a407892.activity-details) ![Main Court](https://mediaim.expedia.com/localexpert/3828671/4b88bad2-0c7e-40af-9458-02ab4e7c72f6.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### 90 Minute Open Jump at a Trampoline Park in Kissimmee CA $32 per adult [](https://expedia.ca/things-to-do/90-minute-open-jump-at-a-trampoline-park-in-kissimmee.a3828671.activity-details) ![Orlando: Dune Buggy Tour](https://mediaim.expedia.com/localexpert/4525768/6b1d5b22-06df-4e22-abfb-7a7b43569d2d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Orlando: Dune Buggy Tour CA $127 per adult **96%** of travellers recommend [](https://expedia.ca/things-to-do/orlando-dune-buggy-tour.a4525768.activity-details) ![MCO Orlando International Airport: Plaza Premium Lounge](https://mediaim.expedia.com/localexpert/4290803/ae71df18-bc47-44fd-937b-6c6c70274d78.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### MCO Orlando International Airport: Plaza Premium Lounge CA $85 per adult [](https://expedia.ca/things-to-do/mco-orlando-international-airport-plaza-premium-lounge.a4290803.activity-details) ![Free splash pad next to the sandy beach at St. Cloud Lakefront Park, the Sand Hill Crane Capital of the World!](https://mediaim.expedia.com/localexpert/48489231/ab482ddc-26ba-4d13-8506-68a4338264a9.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Epic 2-Hour Kissimmee E-Bike Adventure Awaits with Toho Bikes! CA $55 per adult **100%** of travellers recommend [](https://expedia.ca/things-to-do/epic-2-hour-kissimmee-e-bike-adventure-awaits-with-toho-bikes.a48489231.activity-details) ![2-Hour Clear Kayak & Clear Paddleboar](https://mediaim.expedia.com/localexpert/695430/64b46cb0-51fa-464b-9231-a525d0c80253.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### 2-Hour Clear Kayak and Paddleboard(SUP) Rental in Orlando CA $62 per adult **100%** of travellers recommend [](https://expedia.ca/things-to-do/2-hour-clear-kayak-and-paddleboardsup-rental-in-orlando.a695430.activity-details) [See all activities in Orlando](https://expedia.ca/Things-To-Do-In-Orlando.d178294.Travel-Guide-Activities) --- ## Lake Nona Medical City Hotel Deals ![DoubleTree by Hilton Hotel Orlando at SeaWorld](https://images.trvl-media.com/lodging/1000000/20000/18900/18874/69019073_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### DoubleTree by Hilton Hotel Orlando at SeaWorld 10100 International Drive Orlando FL CA $90 CA $141 total Dec 22 - Dec 23 includes taxes & fees Book a stay at this family-friendly resort in Orlando. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the breakfast and the pool in our ... 7.4/10 Good! (6,230 reviews) Great location friendly staff Reviewed on Dec 9, 2025 [](https://expedia.ca/Hotel-Search?startDate=22%2F12%2F2025&endDate=23%2F12%2F2025&selected=18874&PinnedHotelID=18874&HadPinnedHotel=true®ionId=6197057) ![Universal's Cabana Bay Beach Resort](https://images.trvl-media.com/lodging/6000000/5970000/5963300/5963292/63940f45_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Universal's Cabana Bay Beach Resort 6550 Adventure Way Orlando FL CA $183 CA $206 total Dec 16 - Dec 17 includes taxes & fees Book a stay at this family-friendly hotel in Orlando. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff in ... 8.8/10 Excellent! (5,744 reviews) Excelentes servicio with the room staff; a very good environment with good entertainment. Reviewed on Dec 14, 2025 [](https://expedia.ca/Hotel-Search?startDate=16%2F12%2F2025&endDate=17%2F12%2F2025&selected=5963292&PinnedHotelID=5963292&HadPinnedHotel=true®ionId=6197057) ![Rosen Inn at Pointe Orlando](https://images.trvl-media.com/lodging/1000000/10000/8900/8892/8068a653_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Rosen Inn at Pointe Orlando 9000 International Drive Orlando FL CA $90 CA $102 total Dec 16 - Dec 17 includes taxes & fees Book a stay at this family-friendly hotel in Orlando. Enjoy free WiFi, 3 outdoor pools, and 2 coffee shops/cafes. Our guests praise the pool and the helpful ... 8.4/10 Very Good! (5,403 reviews) Clean room but smelled wet. Very nice check in staff. Love staying at this hotel. Reviewed on Dec 14, 2025 [](https://expedia.ca/Hotel-Search?startDate=16%2F12%2F2025&endDate=17%2F12%2F2025&selected=8892&PinnedHotelID=8892&HadPinnedHotel=true®ionId=6197057) ![DoubleTree by Hilton at the Entrance to Universal Orlando](https://images.trvl-media.com/lodging/1000000/10000/5400/5398/4997b5df_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### DoubleTree by Hilton at the Entrance to Universal Orlando 5780 Major Blvd Orlando FL CA $135 CA $152 total Dec 17 - Dec 18 includes taxes & fees Book a stay at this family-friendly hotel in Orlando. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff in ... 8.4/10 Very Good! (6,880 reviews) Amazing staff, very helpful. Reviewed on Dec 12, 2025 [](https://expedia.ca/Hotel-Search?startDate=17%2F12%2F2025&endDate=18%2F12%2F2025&selected=5398&PinnedHotelID=5398&HadPinnedHotel=true®ionId=6197057) ![Wyndham I-Drive Avanti Resort & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/4000/3916/55b45a9e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Wyndham I-Drive Avanti Resort & Conference Center 6515 International Drive Orlando FL CA $86 CA $124 total Dec 17 - Dec 18 includes taxes & fees Book a stay at this business-friendly hotel in Orlando. Enjoy free WiFi, free parking, and private pools. Our guests praise the pool and the clean rooms in our ... 7.2/10 Good! (3,899 reviews) Great, fast and good for the price ! Reviewed on Dec 9, 2025 [](https://expedia.ca/Hotel-Search?startDate=17%2F12%2F2025&endDate=18%2F12%2F2025&selected=3916&PinnedHotelID=3916&HadPinnedHotel=true®ionId=6197057) ![Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando](https://images.trvl-media.com/lodging/1000000/30000/23200/23110/ade3b60d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando 8800 Vistana Centre Dr Orlando FL CA $153 CA $172 total Jan 5 - Jan 6, 2026 includes taxes & fees Book a stay at this family-friendly hotel in Orlando. Enjoy free WiFi, 6 outdoor pools, and 3 restaurants. Our guests praise the pool and the helpful staff in ... 9.2/10 Wonderful! (4,068 reviews) Beautiful resort Reviewed on Dec 9, 2025 [](https://expedia.ca/Hotel-Search?startDate=05%2F01%2F2026&endDate=06%2F01%2F2026&selected=23110&PinnedHotelID=23110&HadPinnedHotel=true®ionId=6197057) [See all 27,650 properties in Lake Nona Medical City](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=16%2F12%2F2025&endDate=17%2F12%2F2025®ionId=6197057) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Lake Nona Medical City hotel availability [Tonight ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=2025-12-15&endDate=2025-12-16)[Dec 15 - Dec 16](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=2025-12-15&endDate=2025-12-16) [Tomorrow night ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=2025-12-16&endDate=2025-12-17)[Dec 16 - Dec 17](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=2025-12-16&endDate=2025-12-17) [This weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=19%2F12%2F2025&endDate=21%2F12%2F2025)[Dec 19 - Dec 21](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=19%2F12%2F2025&endDate=21%2F12%2F2025) [Next weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=26%2F12%2F2025&endDate=28%2F12%2F2025)[Dec 26 - Dec 28](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=26%2F12%2F2025&endDate=28%2F12%2F2025) --- ### Other neighbourhoods around Lake Nona Medical City ![Default Image](https://mediaim.expedia.com/destination/2/118e2bcc2c57d221f91d26ed090668ba.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Lake Nona Mixed-use planned community near Orlando International Airport, Lake Nona offers golf at the prestigious Golf & Country Club and a glimpse into the future with its biomedical research hub, Lake Nona Medical City. [](https://expedia.ca/Orlando-Lake-Nona.dx6209488) ![Default Image](https://mediaim.expedia.com/destination/2/63b613370a0c99115aa319c73749c410.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Airport North While Airport North might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Ventura Country Club and Hoffner Plaza Shopping Center. [](https://expedia.ca/Orlando-Airport-North.dx553248635976479214) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Belle Isle Belle Isle is popular for its ample dining options, and you might make a stop by Lake Conway, a top place to visit in the area. [](https://expedia.ca/Orlando-Belle-Isle.dx6361044) ![Default Image](https://mediaim.expedia.com/destination/2/94317eedf8c28c3b2a9fd4e45c6579aa.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Hunters Creek You'll enjoy the restaurants and shopping in Hunters Creek. You might want to make time for a stop at Shingle Creek Regional Park or Hunters Creek Golf Club. [](https://expedia.ca/Orlando-Hunters-Creek.dx6177981) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### South Semoran If you're looking for some top things to see and do in South Semoran and surrounding area, you can visit Ventura Country Club and Hoffner Plaza Shopping Center. [](https://expedia.ca/Orlando-South-Semoran.dx553248635976473903) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Williamsburg 5/5(16 area reviews) The restaurants, shopping, and golf courses are just a few things travelers enjoy about Williamsburg. If you want to experience more of the area, check out Aquatica or Shingle Creek Golf Course. [](https://expedia.ca/Orlando-Williamsburg.dx6151795) --- --- - [Stays](?pwaLob=wizard-hotel-pwa-v2) - [Packages](?pwaLob=wizard-package-pwa) - [Flights](?pwaLob=wizard-flight-pwa) - [Things to do](?pwaLob=wizard-lx-pwa) - [Cruises](?pwaLob=wizard-cruise-pwa) - [Cars](?pwaLob=wizard-car-pwa) # Lake Nona Medical City ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app