Title: Visit Lake Nona Medical City: Best of Lake Nona Medical City, Orlando Travel 2026 | Expedia Tourism - Expedia.ca [Hotels in Lake Nona Medical City](https://expedia.ca/Lake-Nona-Medical-City-Orlando-Hotels.0-n6197057-0.Travel-Guide-Filter-Hotels)[Flights to Orlando](https://expedia.ca/Cheap-Flights-To-Orlando.d178294.Travel-Guide-Flights)[Things to do in Orlando](https://expedia.ca/Things-To-Do-In-Orlando.d178294.Travel-Guide-Activities)[Lake Nona Medical City Car Rentals](https://expedia.ca/Car-Rentals-In-Lake-Nona-Medical-City.d6197057.Car-Rental-Guide)[Lake Nona Medical City Vacations](https://expedia.ca/Lake-Nona-Medical-City.d6197057.Destination-Travel-Guides) # Lake Nona Medical City ## Orlando ## Visit Lake Nona Medical City Things to do Hotels Where to stay [Orlando travel guide](https://expedia.ca/Orlando.dx178294) --- ### Popular places to visit ![Walt Disney World® Resort](https://images.trvl-media.com/place/6034120/a6e2fb5b-4859-4b13-8673-5364decc02ec.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Walt Disney World® Resort Walt Disney World® Resort is part of Orlando. It makes up part of bustling metropolis that is home to 240,000 inhabitants. Walt Disney World® Resort is approximately 15 miles (24 kilometers) from Orlando’s city center. If you are flying in, Walt Disney World® Resort is approximately 15 miles (24 kilometers) from Orlando International Airport. [](https://expedia.ca/Walt-Disney-World-Resort-Orlando.d6034120.Vacation-Attraction) ![Universal Studios Florida™](https://images.trvl-media.com/place/6049239/81061cd5-1210-4715-a806-d6865f85e0b2.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Universal Studios Florida Movie sets and thrill rides combine to create this internationally acclaimed theme park. [](https://expedia.ca/Universal-Studios-Florida-Florida-Center.d6049239.Vacation-Attraction) ![Universal Studios Orlando which includes street scenes, a city and rides](https://images.trvl-media.com/place/6049239/75d545e9-4a50-4b21-9fd2-665c3f6b014f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Universal Orlando Resort Make your Florida vacation one to remember with a stay at this hotel and theme park complex. [](https://expedia.ca/Universal-Orlando-Resort-Florida-Center.d6347698.Vacation-Attraction) ![Disney Springs® showing a river or creek, a bridge and a sunset](https://images.trvl-media.com/place/502131/67928671-2a47-49aa-9f5b-bb7b815d8ef4.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Disney Springs™ You can search for that perfect souvenir when you visit Disney Springs™, a favorite shopping spot in Lake Buena Vista. Experience the entertainment choices and acclaimed theater scene in this family-friendly area. [](https://expedia.ca/Disney-SpringsTM-Orlando.d502131.Vacation-Attraction) ![Magic Kingdom® Park showing rides](https://images.trvl-media.com/place/6123797/f10815f5-a2a4-401b-bc5f-d73d18b3dc59.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Magic Kingdom® Park One of the most famous theme parks in the world offers a land of fun and fantasy at the foot of a fairytale castle. [](https://expedia.ca/Magic-Kingdom-Park-Bay-Lake.d6123797.Vacation-Attraction) ![Orange County Convention Center showing modern architecture and theater scenes](https://images.trvl-media.com/place/6034972/4d1aece6-6b29-439a-9cc1-4491599eb1c4.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Orange County Convention Center Florida's principal convention center is a large and stunning glass and metal building that hosts national and international trade shows and public events. [](https://expedia.ca/Orange-County-Convention-Center-International-Drive-District.d6034972.Vacation-Attraction) ### Things to do ![Universal Orlando Resort Theme Park Tickets](https://mediaim.expedia.com/localexpert/449578/292355e4-a5b6-4251-bddb-ccea0177846f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Universal Orlando Resort Theme Park Tickets (US & Canada) CA $209 per adult **86%** of travellers recommend [](https://expedia.ca/things-to-do/universal-orlando-resort-theme-park-tickets-us-canada.a449578.activity-details) ![Aquatica Orlando](https://mediaim.expedia.com/localexpert/407892/33b09fce-abbf-446b-bce5-738d4c15128d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Aquatica Orlando CA $73 per traveller **84%** of travellers recommend [](https://expedia.ca/things-to-do/aquatica-orlando.a407892.activity-details) ![Florida: 90 Minute Everglades Cruise](https://mediaim.expedia.com/localexpert/47891876/33dc2687-1323-4f4f-83b1-a21a4a724609.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Florida: 90 Minute Everglades Cruise CA $76 per adult **100%** of travellers recommend [](https://expedia.ca/things-to-do/florida-90-minute-everglades-cruise.a47891876.activity-details) ![Main Court](https://mediaim.expedia.com/localexpert/3828671/4b88bad2-0c7e-40af-9458-02ab4e7c72f6.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### 90 Minute Open Jump at a Trampoline Park in Kissimmee CA $31 per adult [](https://expedia.ca/things-to-do/90-minute-open-jump-at-a-trampoline-park-in-kissimmee.a3828671.activity-details) ![Orlando: Dune Buggy Tour](https://mediaim.expedia.com/localexpert/4525768/6b1d5b22-06df-4e22-abfb-7a7b43569d2d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Orlando: Dune Buggy Tour CA $125 per adult **96%** of travellers recommend [](https://expedia.ca/things-to-do/orlando-dune-buggy-tour.a4525768.activity-details) ![MCO Orlando International Airport: Plaza Premium Lounge](https://mediaim.expedia.com/localexpert/4290803/ae71df18-bc47-44fd-937b-6c6c70274d78.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### MCO Orlando International Airport: Plaza Premium Lounge CA $85 per adult [](https://expedia.ca/things-to-do/mco-orlando-international-airport-plaza-premium-lounge.a4290803.activity-details) [See all activities in Orlando](https://expedia.ca/Things-To-Do-In-Orlando.d178294.Travel-Guide-Activities) --- ## Lake Nona Medical City Hotel Deals ![Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando](https://images.trvl-media.com/lodging/1000000/30000/23200/23110/ade3b60d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando 8800 Vistana Centre Dr Orlando FL CA $157 CA $177 total Feb 25 - Feb 26 includes taxes & fees Book a stay at this family-friendly hotel in Orlando. Enjoy free WiFi, 6 outdoor pools, and 3 restaurants. Our guests praise the pool and the helpful staff in ... 9.2/10 Wonderful! (4,489 reviews) The condo was clean. The staff was friendly. The beds were comfortable and the coffee bar was great. Thank you so much. Reviewed on Feb 2, 2026 [](https://expedia.ca/Hotel-Search?startDate=25%2F02%2F2026&endDate=26%2F02%2F2026&selected=23110&PinnedHotelID=23110&HadPinnedHotel=true®ionId=6197057) ![Rosen Inn at Pointe Orlando](https://images.trvl-media.com/lodging/1000000/10000/8900/8892/8068a653_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Rosen Inn at Pointe Orlando 9000 International Drive Orlando FL CA $101 CA $114 total Feb 21 - Feb 22 includes taxes & fees Book a stay at this family-friendly hotel in Orlando. Enjoy free WiFi, 3 outdoor pools, and 2 coffee shops/cafes. Our guests praise the pool and the helpful ... 8.4/10 Very Good! (5,659 reviews) Everything was fine except they now charge for parking. I've stayed at this location 3 times total. Reviewed on Feb 3, 2026 [](https://expedia.ca/Hotel-Search?startDate=21%2F02%2F2026&endDate=22%2F02%2F2026&selected=8892&PinnedHotelID=8892&HadPinnedHotel=true®ionId=6197057) ![DoubleTree by Hilton Hotel Orlando at SeaWorld](https://images.trvl-media.com/lodging/1000000/20000/18900/18874/69019073_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### DoubleTree by Hilton Hotel Orlando at SeaWorld 10100 International Drive Orlando FL CA $100 CA $151 total Mar 8 - Mar 9 includes taxes & fees Book a stay at this family-friendly resort in Orlando. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the breakfast and the pool in our ... 7.4/10 Good! (6,525 reviews) Staff was courteous. Only issue is the room is older and had a musty smell. Mayb an upgrade to the rooms will be better didn’t match the ascetic of the lobby which looked newly renovated. Hotel was convenient close to parks and convention center. Easy to get ubers etc. The shuttle bus service wasn't ... Reviewed on Feb 3, 2026 [](https://expedia.ca/Hotel-Search?startDate=08%2F03%2F2026&endDate=09%2F03%2F2026&selected=18874&PinnedHotelID=18874&HadPinnedHotel=true®ionId=6197057) ![Universal's Cabana Bay Beach Resort](https://images.trvl-media.com/lodging/6000000/5970000/5963300/5963292/63940f45_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Universal's Cabana Bay Beach Resort 6550 Adventure Way Orlando FL CA $186 CA $209 total Feb 10 - Feb 11 includes taxes & fees Book a stay at this family-friendly hotel in Orlando. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff in ... 8.8/10 Excellent! (6,247 reviews) Clear. Customer service. Transportation convenience Reviewed on Feb 3, 2026 [](https://expedia.ca/Hotel-Search?startDate=10%2F02%2F2026&endDate=11%2F02%2F2026&selected=5963292&PinnedHotelID=5963292&HadPinnedHotel=true®ionId=6197057) ![Orlando International Drive North Hotel](https://images.trvl-media.com/lodging/1000000/50000/41500/41493/d062739a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Orlando International Drive North Hotel 5859 American Way Orlando FL CA $101 CA $137 total Feb 12 - Feb 13 includes taxes & fees Book a stay at this business-friendly hotel in Orlando. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ... 7.2/10 Good! (2,781 reviews) Staff were super friendly, especially the man at the front desk! Room was clean, no smell. Highly recommend. Reviewed on Feb 2, 2026 [](https://expedia.ca/Hotel-Search?startDate=12%2F02%2F2026&endDate=13%2F02%2F2026&selected=41493&PinnedHotelID=41493&HadPinnedHotel=true®ionId=6197057) ![Wyndham I-Drive Avanti Resort & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/4000/3916/55b45a9e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Wyndham I-Drive Avanti Resort & Conference Center 6515 International Drive Orlando FL CA $103 CA $144 total Feb 8 - Feb 9 includes taxes & fees Book a stay at this business-friendly hotel in Orlando. Enjoy free WiFi, free parking, and private pools. Our guests praise the pool and the clean rooms in our ... 7.2/10 Good! (4,154 reviews) Staff was very good Reviewed on Feb 3, 2026 [](https://expedia.ca/Hotel-Search?startDate=08%2F02%2F2026&endDate=09%2F02%2F2026&selected=3916&PinnedHotelID=3916&HadPinnedHotel=true®ionId=6197057) [See all 27,606 properties in Lake Nona Medical City](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=06%2F02%2F2026&endDate=07%2F02%2F2026®ionId=6197057) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Lake Nona Medical City hotel availability [Tonight ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=2026-02-05&endDate=2026-02-06)[Feb 5 - Feb 6](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=2026-02-05&endDate=2026-02-06) [Tomorrow night ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=2026-02-06&endDate=2026-02-07)[Feb 6 - Feb 7](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=2026-02-06&endDate=2026-02-07) [This weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=06%2F02%2F2026&endDate=08%2F02%2F2026)[Feb 6 - Feb 8](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=06%2F02%2F2026&endDate=08%2F02%2F2026) [Next weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026)[Feb 13 - Feb 15](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026) --- ### Other neighbourhoods around Lake Nona Medical City ![Two chairs sitting in a park by a lake in Laurete Park in Lake Nona, Orlando, FL on a beautiful sunny day.](https://images.trvl-media.com/place/6209488/e6ddeb2f-1926-4eed-96af-b0a6f81ea247.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Lake Nona Mixed-use planned community near Orlando International Airport, Lake Nona offers golf at the prestigious Golf & Country Club and a glimpse into the future with its biomedical research hub, Lake Nona Medical City. [](https://expedia.ca/Orlando-Lake-Nona.dx6209488) ![Orlando, FL cityscape](https://images.trvl-media.com/place/553248635976479214/127918f1-fd89-4181-ba41-abb9d0d0169a.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Airport North While Airport North might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Ventura Country Club and Rio Pinar Country Club. [](https://expedia.ca/Orlando-Airport-North.dx553248635976479214) ![Orlando, Florida, USA Skyline](https://images.trvl-media.com/place/6177981/ede06224-d01a-4675-babe-b7d164b3bedf.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Hunters Creek You'll enjoy the restaurants and shopping in Hunters Creek. You might want to make time for a stop at Shingle Creek Regional Park or Hunters Creek Golf Club. [](https://expedia.ca/Orlando-Hunters-Creek.dx6177981) ![Panoramic aerial view of Lake Eola and surrounding buildings, Orlando - Florida](https://images.trvl-media.com/place/553248635976472820/09332cf4-66e2-40dc-95ba-a7a550f666e1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### South Semoran If you're looking for some top things to see and do in South Semoran and surrounding area, you can visit Ventura Country Club and Hoffner Plaza Shopping Center. [](https://expedia.ca/Orlando-South-Semoran.dx553248635976473903) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Williamsburg 5/5(16 area reviews) The restaurants, shopping, and golf courses are just a few things travelers enjoy about Williamsburg. If you want to experience more of the area, check out Aquatica or Shingle Creek Golf Course. [](https://expedia.ca/Orlando-Williamsburg.dx6151795) ![Orlando morning](https://images.trvl-media.com/place/553248635976469850/55ead01e-0edb-47fc-bbde-41a77955d7b1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Oak Ridge Oak Ridge is noteworthy for its theme parks, and you can make a stop at top attractions like Cross Country Creek and Central Park Plaza Shopping Center. [](https://expedia.ca/Orlando-Oak-Ridge.dx6361036) --- --- - [Stays](?pwaLob=wizard-hotel-pwa-v2) - [Packages](?pwaLob=wizard-package-pwa) - [Flights](?pwaLob=wizard-flight-pwa) - [Things to do](?pwaLob=wizard-lx-pwa) - [Cruises](?pwaLob=wizard-cruise-pwa) - [Cars](?pwaLob=wizard-car-pwa) # Lake Nona Medical City ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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