Title: Visit Lake Nona Medical City: Best of Lake Nona Medical City, Orlando Travel 2026 | Expedia Tourism - Expedia.ca [Hotels in Lake Nona Medical City](https://expedia.ca/Lake-Nona-Medical-City-Orlando-Hotels.0-n6197057-0.Travel-Guide-Filter-Hotels)[Flights to Orlando](https://expedia.ca/Cheap-Flights-To-Orlando.d178294.Travel-Guide-Flights)[Things to do in Orlando](https://expedia.ca/Things-To-Do-In-Orlando.d178294.Travel-Guide-Activities)[Lake Nona Medical City Car Rentals](https://expedia.ca/Car-Rentals-In-Lake-Nona-Medical-City.d6197057.Car-Rental-Guide)[Lake Nona Medical City Vacations](https://expedia.ca/Lake-Nona-Medical-City.d6197057.Destination-Travel-Guides) # Lake Nona Medical City ## Orlando ## Visit Lake Nona Medical City Things to do Hotels Where to stay [Orlando travel guide](https://expedia.ca/Orlando.dx178294) --- ### Popular places to visit ![Walt Disney World® Resort](https://images.trvl-media.com/place/6034120/a6e2fb5b-4859-4b13-8673-5364decc02ec.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Walt Disney World® Resort 4.5/5(226 reviews) Walt Disney World® Resort is part of Orlando. It makes up part of bustling metropolis that is home to 240,000 inhabitants. Walt Disney World® Resort is approximately 15 miles (24 kilometers) from Orlando’s city center. If you are flying in, Walt Disney World® Resort is approximately 15 miles (24 kilometers) from Orlando International Airport. [](https://expedia.ca/Walt-Disney-World-Resort-Orlando.d6034120.Vacation-Attraction) ![Universal Studios Florida™](https://images.trvl-media.com/place/6049239/81061cd5-1210-4715-a806-d6865f85e0b2.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Universal Studios Florida 4.5/5(988 reviews) Movie sets and thrill rides combine to create this internationally acclaimed theme park. [](https://expedia.ca/Universal-Studios-Florida-Florida-Center.d6049239.Vacation-Attraction) ![Universal Studios Orlando which includes street scenes, a city and rides](https://images.trvl-media.com/place/6049239/75d545e9-4a50-4b21-9fd2-665c3f6b014f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Universal Orlando Resort 4.5/5(399 reviews) Make your Florida vacation one to remember with a stay at this hotel and theme park complex. [](https://expedia.ca/Universal-Orlando-Resort-Florida-Center.d6347698.Vacation-Attraction) ![Disney Springs® showing a river or creek, a bridge and a sunset](https://images.trvl-media.com/place/502131/67928671-2a47-49aa-9f5b-bb7b815d8ef4.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Disney Springs™ 4.5/5(1,107 reviews) You can search for that perfect souvenir when you visit Disney Springs™, a favorite shopping spot in Lake Buena Vista. Experience the entertainment choices and acclaimed theater scene in this family-friendly area. [](https://expedia.ca/Disney-SpringsTM-Orlando.d502131.Vacation-Attraction) ![Magic Kingdom® Park showing rides](https://images.trvl-media.com/place/6123797/f10815f5-a2a4-401b-bc5f-d73d18b3dc59.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Magic Kingdom® Park 4.5/5(916 reviews) One of the most famous theme parks in the world offers a land of fun and fantasy at the foot of a fairytale castle. [](https://expedia.ca/Magic-Kingdom-Park-Bay-Lake.d6123797.Vacation-Attraction) ![Orange County Convention Center showing modern architecture and theater scenes](https://images.trvl-media.com/place/6034972/4d1aece6-6b29-439a-9cc1-4491599eb1c4.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Orange County Convention Center 4.5/5(124 reviews) Florida's principal convention center is a large and stunning glass and metal building that hosts national and international trade shows and public events. [](https://expedia.ca/Orange-County-Convention-Center-International-Drive-District.d6034972.Vacation-Attraction) ### Things to do ![Aquatica Orlando](https://mediaim.expedia.com/localexpert/407892/33b09fce-abbf-446b-bce5-738d4c15128d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Aquatica Orlando CA $73 per traveller **84%** of travellers recommend [](https://expedia.ca/things-to-do/aquatica-orlando.a407892.activity-details) ![Florida: 90 Minute Everglades Cruise](https://mediaim.expedia.com/localexpert/47891876/33dc2687-1323-4f4f-83b1-a21a4a724609.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Florida: 90 Minute Everglades Cruise CA $76 per adult **100%** of travellers recommend [](https://expedia.ca/things-to-do/florida-90-minute-everglades-cruise.a47891876.activity-details) ![Main Court](https://mediaim.expedia.com/localexpert/3828671/4b88bad2-0c7e-40af-9458-02ab4e7c72f6.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### 90 Minute Open Jump at a Trampoline Park in Kissimmee CA $31 per adult [](https://expedia.ca/things-to-do/90-minute-open-jump-at-a-trampoline-park-in-kissimmee.a3828671.activity-details) ![Orlando: Dune Buggy Tour](https://mediaim.expedia.com/localexpert/4525768/6b1d5b22-06df-4e22-abfb-7a7b43569d2d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Orlando: Dune Buggy Tour CA $125 per adult **96%** of travellers recommend [](https://expedia.ca/things-to-do/orlando-dune-buggy-tour.a4525768.activity-details) ![MCO Orlando International Airport: Plaza Premium Lounge](https://mediaim.expedia.com/localexpert/4290803/ae71df18-bc47-44fd-937b-6c6c70274d78.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### MCO Orlando International Airport: Plaza Premium Lounge CA $85 per adult [](https://expedia.ca/things-to-do/mco-orlando-international-airport-plaza-premium-lounge.a4290803.activity-details) ![2-Hour Clear Kayak & Clear Paddleboar](https://mediaim.expedia.com/localexpert/695430/64b46cb0-51fa-464b-9231-a525d0c80253.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### 2-Hour Clear Kayak and Paddleboard(SUP) Rental in Orlando CA $62 per adult **100%** of travellers recommend [](https://expedia.ca/things-to-do/2-hour-clear-kayak-and-paddleboardsup-rental-in-orlando.a695430.activity-details) [See all activities in Orlando](https://expedia.ca/Things-To-Do-In-Orlando.d178294.Travel-Guide-Activities) --- ## Lake Nona Medical City Hotel Deals ![Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando](https://images.trvl-media.com/lodging/1000000/30000/23200/23110/ade3b60d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando 8800 Vistana Centre Dr Orlando FL CA $156 CA $176 total Feb 23 - Feb 24 includes taxes & fees Book a stay at this family-friendly hotel in Orlando. Enjoy free WiFi, 6 outdoor pools, and 3 restaurants. Our guests praise the pool and the helpful staff in ... 9.2/10 Wonderful! (4,432 reviews) We only stayed one night but villa was huge clean and very nice Reviewed on Jan 27, 2026 [](https://expedia.ca/Hotel-Search?startDate=23%2F02%2F2026&endDate=24%2F02%2F2026&selected=23110&PinnedHotelID=23110&HadPinnedHotel=true®ionId=6197057) ![Hyatt Regency Orlando International Airport](https://images.trvl-media.com/lodging/1000000/10000/2800/2754/acaa1e8b_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hyatt Regency Orlando International Airport 9300 Jeff Fuqua Boulevard Orlando FL CA $487 CA $548 total Feb 22 - Feb 23 includes taxes & fees Book a stay at this business-friendly hotel in Orlando. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ... 9.4/10 Exceptional! (3,944 reviews) Clean spacious room, comfortable bed. Super convenient to get to security. Reviewed on Jan 27, 2026 [](https://expedia.ca/Hotel-Search?startDate=22%2F02%2F2026&endDate=23%2F02%2F2026&selected=2754&PinnedHotelID=2754&HadPinnedHotel=true®ionId=6197057) ![DoubleTree by Hilton at the Entrance to Universal Orlando](https://images.trvl-media.com/lodging/1000000/10000/5400/5398/4997b5df_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### DoubleTree by Hilton at the Entrance to Universal Orlando 5780 Major Blvd Orlando FL CA $132 CA $149 total Feb 23 - Feb 24 includes taxes & fees Book a stay at this family-friendly hotel in Orlando. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff in ... 8.4/10 Very Good! (6,964 reviews) Location was perfect if you want to go to Universal Studios/Islands of Adventure. The room was clean and cozy. Front desk was courteous and friendly. Our stay overall was great with the exception of the elevators being down on our final day and having to take the service elevators other than that, ... Reviewed on Jan 26, 2026 [](https://expedia.ca/Hotel-Search?startDate=23%2F02%2F2026&endDate=24%2F02%2F2026&selected=5398&PinnedHotelID=5398&HadPinnedHotel=true®ionId=6197057) ![Universal's Cabana Bay Beach Resort](https://images.trvl-media.com/lodging/6000000/5970000/5963300/5963292/63940f45_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Universal's Cabana Bay Beach Resort 6550 Adventure Way Orlando FL CA $181 CA $204 total Feb 3 - Feb 4 includes taxes & fees Book a stay at this family-friendly hotel in Orlando. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff in ... 8.8/10 Excellent! (6,160 reviews) The room was clean but it felt like the box spring on one bed was broken. Reviewed on Jan 24, 2026 [](https://expedia.ca/Hotel-Search?startDate=03%2F02%2F2026&endDate=04%2F02%2F2026&selected=5963292&PinnedHotelID=5963292&HadPinnedHotel=true®ionId=6197057) ![Rosen Inn at Pointe Orlando](https://images.trvl-media.com/lodging/1000000/10000/8900/8892/8068a653_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Rosen Inn at Pointe Orlando 9000 International Drive Orlando FL CA $103 CA $116 total Feb 21 - Feb 22 includes taxes & fees Book a stay at this family-friendly hotel in Orlando. Enjoy free WiFi, 3 outdoor pools, and 2 coffee shops/cafes. Our guests praise the pool and the helpful ... 8.4/10 Very Good! (5,608 reviews) Zero complaints. I will go back Reviewed on Jan 23, 2026 [](https://expedia.ca/Hotel-Search?startDate=21%2F02%2F2026&endDate=22%2F02%2F2026&selected=8892&PinnedHotelID=8892&HadPinnedHotel=true®ionId=6197057) ![Universal's Endless Summer Resort - Dockside Inn and Suites](https://images.trvl-media.com/lodging/34000000/33780000/33770400/33770341/c8859517_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Universal's Endless Summer Resort - Dockside Inn and Suites 7125 Universal Boulevard Orlando FL Fully refundableReserve now, pay when you stay CA $154 CA $174 total Mar 1 - Mar 2 includes taxes & fees Book a stay at this family-friendly hotel in Orlando. Enjoy free WiFi, 2 outdoor pools, and 3 bars/lounges. Our guests praise the pool and the restaurant in ... 9/10 Wonderful! (5,086 reviews) Quick check-in and earlier than expected! Should have shuttles to & from airport! So close Reviewed on Jan 24, 2026 [](https://expedia.ca/Hotel-Search?startDate=01%2F03%2F2026&endDate=02%2F03%2F2026&selected=33770341&PinnedHotelID=33770341&HadPinnedHotel=true®ionId=6197057) [See all 27,600 properties in Lake Nona Medical City](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=30%2F01%2F2026&endDate=31%2F01%2F2026®ionId=6197057) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Lake Nona Medical City hotel availability [Tonight ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=2026-01-29&endDate=2026-01-30)[Jan 29 - Jan 30](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=2026-01-29&endDate=2026-01-30) [Tomorrow night ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=2026-01-30&endDate=2026-01-31)[Jan 30 - Jan 31](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=2026-01-30&endDate=2026-01-31) [This weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=30%2F01%2F2026&endDate=01%2F02%2F2026)[Jan 30 - Feb 1](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=30%2F01%2F2026&endDate=01%2F02%2F2026) [Next weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=06%2F02%2F2026&endDate=08%2F02%2F2026)[Feb 6 - Feb 8](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=06%2F02%2F2026&endDate=08%2F02%2F2026) --- ### Other neighbourhoods around Lake Nona Medical City ![Two chairs sitting in a park by a lake in Laurete Park in Lake Nona, Orlando, FL on a beautiful sunny day.](https://images.trvl-media.com/place/6209488/e6ddeb2f-1926-4eed-96af-b0a6f81ea247.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Lake Nona Mixed-use planned community near Orlando International Airport, Lake Nona offers golf at the prestigious Golf & Country Club and a glimpse into the future with its biomedical research hub, Lake Nona Medical City. [](https://expedia.ca/Orlando-Lake-Nona.dx6209488) ![Orlando, FL cityscape](https://images.trvl-media.com/place/553248635976479214/127918f1-fd89-4181-ba41-abb9d0d0169a.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Airport North While Airport North might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Ventura Country Club and Rio Pinar Country Club. [](https://expedia.ca/Orlando-Airport-North.dx553248635976479214) ![Orlando, Florida, USA Skyline](https://images.trvl-media.com/place/6177981/ede06224-d01a-4675-babe-b7d164b3bedf.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Hunters Creek You'll enjoy the restaurants and shopping in Hunters Creek. You might want to make time for a stop at Shingle Creek Regional Park or Hunters Creek Golf Club. [](https://expedia.ca/Orlando-Hunters-Creek.dx6177981) ![Panoramic aerial view of Lake Eola and surrounding buildings, Orlando - Florida](https://images.trvl-media.com/place/553248635976472820/09332cf4-66e2-40dc-95ba-a7a550f666e1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### South Semoran If you're looking for some top things to see and do in South Semoran and surrounding area, you can visit Ventura Country Club and Hoffner Plaza Shopping Center. [](https://expedia.ca/Orlando-South-Semoran.dx553248635976473903) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Williamsburg 5/5(16 area reviews) The restaurants, shopping, and golf courses are just a few things travelers enjoy about Williamsburg. If you want to experience more of the area, check out Aquatica or Shingle Creek Golf Course. [](https://expedia.ca/Orlando-Williamsburg.dx6151795) ![Orlando morning](https://images.trvl-media.com/place/553248635976469850/55ead01e-0edb-47fc-bbde-41a77955d7b1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Oak Ridge Oak Ridge is noteworthy for its theme parks, and you can make a stop at top attractions like Cross Country Creek and Central Park Plaza Shopping Center. [](https://expedia.ca/Orlando-Oak-Ridge.dx6361036) --- --- - [Stays](?pwaLob=wizard-hotel-pwa-v2) - [Packages](?pwaLob=wizard-package-pwa) - [Flights](?pwaLob=wizard-flight-pwa) - [Things to do](?pwaLob=wizard-lx-pwa) - [Cruises](?pwaLob=wizard-cruise-pwa) - [Cars](?pwaLob=wizard-car-pwa) # Lake Nona Medical City ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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